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UniProtKB/Swiss-Prot entry A8YV48

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name TRMFO_LACH4
Primary accession number A8YV48
Secondary accession numbers None
Integrated into Swiss-Prot on September 2, 2008
Sequence was last modified on January 15, 2008 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 10)
Name and origin of the protein
Protein name Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase trmFO
Synonyms EC 2.1.1.74
Folate-dependent tRNA (uracil-5-)-methyltransferase
Folate-dependent tRNA(M-5-U54)-methyltransferase
Gene name
Name: trmFO
OrderedLocusNames: lhv_1075
From
Lactobacillus helveticus (strain DPC 4571) [TaxID: 405566] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.01295-07; PubMed=17993529 [NCBI, ExPASy, EBI, Israel, Japan]
Callanan M., Kaleta P., O'Callaghan J., O'Sullivan O., Jordan K., McAuliffe O., Sangrador-Vegas A., Slattery L., Fitzgerald G.F., Beresford T., Ross R.P.;
"Genome sequence of Lactobacillus helveticus: an organism distinguished by selective gene loss and IS element expansion.";
J. Bacteriol. 190:727-735(2008).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000517; ABX27136.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001577427.1; -.
3D structure databases
ModBase A8YV48.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0050660; Molecular function: FAD binding (inferred from electronic annotation from HAMAP).
GO:0047151; Molecular function: methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity (inferred from electronic annotation from EC).
GO:0009021; Molecular function: tRNA (uracil-5-)-methyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0008033; Biological process: tRNA processing (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01037; -; 1.
PBIL [Tree]
InterPro IPR004417; Gid.
IPR002218; GIDA.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR11806; GIDA; 1.
Pfam PF01134; GIDA; 1.
Pfam graphical view of domain structure.
ProDom PD003738; GIDA; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00137; gid_trmFO; 1.
PROSITE PS01280; GIDA_1; FALSE_NEG.
PS01281; GIDA_2; 1.
Genome annotation databases
GeneID 5771781; -.
GenomeReviews CP000517_GR; lhv_1075.
KEGG lhe:lhv_1075; -.
CMR A8YV48; lhv_1075.
Other
ProtoNet A8YV48.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; FAD; Flavoprotein; Methyltransferase; Transferase; tRNA processing.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   407  407     Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase trmFO. PRO_0000346347
NP_BIND   9    14  6     FAD (By similarity). 
Sequence information
Length: 407 AA [This is the length of the unprocessed precursor] Molecular weight: 44505 Da [This is the MW of the unprocessed precursor] CRC64: F48EA9357797715A [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MPKNVTVIGA GLAGSEATWQ LAKRGIHVDL YEMRPQKETP AHETGEFAEL VCTNSMRSNQ 

        70         80         90        100        110        120 
LSNAVGLLKE EMRHLDSLIM KAADKTQVPA GGALAVDRDS FSKYVTDTLR GLDNVTVHEE 

       130        140        150        160        170        180 
EITEIPEDGI TIIATGPLTS DALAEQIQKF SGTDSLHFFD AAAPIVAADS IDMNIVYKKS 

       190        200        210        220        230        240 
RYDRGEAAYL NCPMNKEQYE NFTRELIKAE TAQLHGFEKN DVFEGCMPIE VMAARGAKTM 

       250        260        270        280        290        300 
LFGPLKPVGL EDPHTGETPY AVVQLRQDNA AASMYNIVGF QTHLKYGEQK RVFSMIPGLE 

       310        320        330        340        350        360 
NARFVRYGKM HRNTYMASPD VLTASYEAKK RPGLFFAGQM TGVEGYVESA GSGLVAGVNA 

       370        380        390        400 
AREALGEEPI AFPKDTALGS MANYVTTTSA KHFPPMNASL HFYLLGK
A8YV48 in FASTA format

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