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UniProtKB/Swiss-Prot entry A8HZA8

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DDL_AZOC5
Primary accession number A8HZA8
Secondary accession numbers None
Integrated into Swiss-Prot on June 10, 2008
Sequence was last modified on December 4, 2007 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 9)
Name and origin of the protein
Protein name D-alanine--D-alanine ligase
Synonyms EC 6.3.2.4
D-alanylalanine synthetase
D-Ala-D-Ala ligase
Gene name
Name: ddl
OrderedLocusNames: AZC_4561
From
Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [TaxID: 438753] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Xanthobacteraceae; Azorhizobium.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.;
"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.";
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AP009384; BAF90559.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001527477.1; -.
3D structure databases
ModBase A8HZA8.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0008716; Molecular function: D-alanine-D-alanine ligase activity (inferred from electronic annotation from HAMAP).
GO:0009252; Biological process: peptidoglycan biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00047; -; 1.
PBIL [Tree]
InterPro IPR011761; ATP-grasp.
IPR013816; ATP_grasp_subdomain_2.
IPR000291; D-Ala_lig_Van_CS.
IPR005905; D_ala_D_ala.
IPR011095; Dala_Dala_lig_C.
IPR011127; Dala_Dala_lig_N.
IPR013817; Pre-ATP_grasp.
Graphical view of domain structure.
Gene3D G3DSA:3.30.470.20; ATP_grasp_subdomain_2; 1.
G3DSA:3.40.50.20; Pre-ATP_grasp; 1.
Pfam PF07478; Dala_Dala_lig_C; 1.
PF01820; Dala_Dala_lig_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01205; D_ala_D_alaTIGR; 1.
PROSITE PS50975; ATP_GRASP; 1.
PS00843; DALA_DALA_LIGASE_1; 1.
PS00844; DALA_DALA_LIGASE_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS A8HZA8.
Genome annotation databases
GeneID 5689654; -.
GenomeReviews AP009384_GR; AZC_4561.
CMR A8HZA8; AZC_4561.
Other
ProtoNet A8HZA8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Cell shape; Cell wall biogenesis/degradation; Complete proteome; Cytoplasm; Ligase; Magnesium; Manganese; Metal-binding; Nucleotide-binding; Peptidoglycan synthesis.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   306  306     D-alanine--D-alanine ligase. PRO_0000341057
DOMAIN   101   300  200     ATP-grasp. 
NP_BIND   128   182  55     ATP (By similarity). 
METAL   250   250        Magnesium or manganese 1 (By similarity). 
METAL   267   267        Magnesium or manganese 1 (By similarity). 
METAL   267   267        Magnesium or manganese 2 (By similarity). 
METAL   269   269        Magnesium or manganese 2 (By similarity). 
Sequence information
Length: 306 AA [This is the length of the unprocessed precursor] Molecular weight: 32913 Da [This is the MW of the unprocessed precursor] CRC64: 635CE58584325D3E [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAKHVAVLMG GWSPEREVSL RSGAGCAKAL EEVGYRVTRV DVDRDVAEVL ARLKPDVALN 

        70         80         90        100        110        120 
LLHGCPGEDG TIQGILEILR IPYSHSGVLA SALAMDKARA KVVMAAAGIP VPGGHLVTRA 

       130        140        150        160        170        180 
EAAKGHVLPP PYVLKPNTGG SSVGVFIVKE DQPHPPQELF RADWTFGESL MAEPFIKGLE 

       190        200        210        220        230        240 
LTCGVMGDRA LDVIEVEAVH GFYDYESKYA AGGSRHILPA RVLPQIYQQV RMLALEAHRA 

       250        260        270        280        290        300 
LGCRGISRAD FRYDDTLPDG KGLVCLEVNT QPGMTETSLV PDMAAHAGIS FGELVTWMVE 


DATLDR
A8HZA8 in FASTA format

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