[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Miller W.G., Rubenfield M., Wang G., Rogosin A., Malek J., Parker C.T., Stanker L.H., Mandrell R.E.; Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate.
PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from HCO(3)(-): step 2/6 .
SIMILARITY: Belongs to the ATCase/OTCase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000361; ABV66536.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_001489205.1; -.

3D structure databases

ModBase

A8ERG2.

Ontologies

GO:0004070;	Molecular function: aspartate carbamoyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0006221;	Biological process: pyrimidine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00001; -; 1.
PBIL [Tree]

InterPro

IPR006130; Asp/Orn_carbamoyltranf.
IPR006132; Asp/Orn_carbamoyltranf_P_bd.
IPR006131; Asp_carbamoyltransf_Asp/Orn_bd.
IPR002082; Aspartate_carbamoyltransf_euk.
Graphical view of domain structure.

Pfam

PF00185; OTCace; 1.
PF02729; OTCace_N; 1.
Pfam graphical view of domain structure.

PRINTS

PR00100; AOTCASE.
PR00101; ATCASE.

TIGRFAMs

TIGR00670; asp_carb_tr; 1.

PROSITE

PS00097; CARBAMOYLTRANSFERASE; 1.

BLOCKS

A8ERG2.

Genome annotation databases

GeneID

5624951; -.

GenomeReviews

CP000361_GR; Abu_0261.

KEGG

abu:Abu_0261; -.

CMR

A8ERG2; Abu_0261.

Other

ProtoNet

A8ERG2.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Pyrimidine biosynthesis; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 295`	`295`		`Aspartate carbamoyltransferase.`	`PRO_1000057008`

Sequence information

Length: 295 AA [This is the length of the unprocessed precursor]

Molecular weight: 33236 Da [This is the MW of the unprocessed precursor]

CRC64: 0C623460192C91EB [This is a checksum on the sequence]

        10         20         30         40         50         60 
MQHLIRTSDF TKEEILDIFE DARGFLDFKP CEILKGKIIV TLFFENSTRT RSSFEIAAKR 

        70         80         90        100        110        120 
LGAEIVNLDV GTSSTKKGET MYDTVANINA MGPDAIVIRH SECGLPESLI GYVDCPIINA 

       130        140        150        160        170        180 
GDGRHSHPTQ ALLDLFTIYE HFNGQTEGKK IAIVGDVRNS RVAGSNRRLL PRFGIDVNLV 

       190        200        210        220        230        240 
APDCFKYEGN EFKQFNTIAE VIDDMDVVMS LRSQLERHNI TYFESLQEYA KDFCITPELM 

       250        260        270        280        290 
EGRDFLLLHP GPVNRNIDIS DEVLKDPRCK VLEQVRNGVA VRAAILKKLI LNNKN

A8ERG2 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools