NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nbt1325; PubMed=17704766 [NCBI, ExPASy, EBI, Israel, Japan]
Chen X.H., Koumoutsi A., Scholz R., Eisenreich A., Schneider K., Heinemeyer I., Morgenstern B., Voss B., Hess W.R., Reva O., Junge H., Voigt B., Jungblut P.R., Vater J., Suessmuth R., Liesegang H., Strittmatter A., Gottschalk G., Borriss R.;
"Comparative analysis of the complete genome sequence of the plant growth-promoting bacterium Bacillus amyloliquefaciens FZB42.";
Nat. Biotechnol. 25:1007-1014(2007).

Comments

CATALYTIC ACTIVITY: D-mannitol 1-phosphate + NAD⁺ = D-fructose 6-phosphate + NADH.
SIMILARITY: Belongs to the mannitol dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000560; ABS72824.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_001420055.1; -.

3D structure databases

ModBase

A7Z1E8.

Ontologies

GO:0008926;	Molecular function: mannitol-1-phosphate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00196; -; 1.
PBIL [Tree]

InterPro

IPR013328; DHase_multihelical.
IPR013118; Mannitol_DHase_C.
IPR000669; Mannitol_DHase_core.
IPR013131; Mannitol_DHase_N.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.

Pfam

PF01232; Mannitol_dh; 1.
PF08125; Mannitol_dh_C; 1.
Pfam graphical view of domain structure.

PRINTS

PR00084; MTLDHDRGNASE.

PROSITE

PS00974; MANNITOL_DHGENASE; 1.

BLOCKS

A7Z1E8.

Genome annotation databases

GeneID

5459968; -.

GenomeReviews

CP000560_GR; RBAM_004250.

KEGG

bay:RBAM_004250; -.

CMR

A7Z1E8; RBAM_004250.

Other

ProtoNet

A7Z1E8.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; NAD; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 373`	`373`	`Mannitol-1-phosphate 5-dehydrogenase.`	`PRO_1000011794`
`NP_BIND`	`3 14`	`12`	`NAD (By similarity).`

Sequence information

Length: 373 AA [This is the length of the unprocessed precursor]

Molecular weight: 41164 Da [This is the MW of the unprocessed precursor]

CRC64: 50DF9BE1E9D5B33A [This is a checksum on the sequence]

        10         20         30         40         50         60 
MIALHFGAGN IGRGFIGALL HHSGYDVVFA DVNETMVSLL NEKKEYTVEL ADGGRQTEII 

        70         80         90        100        110        120 
GPVSAINSAV QEQKLYRLIN EAAIITTAVG PNVLRLIAPS IAEGLKRRTS SEPLNIIACE 

       130        140        150        160        170        180 
NMIGGSSFLK KAVFGHLTEA ERELVNRTVG FPDSAVDRIV PIQHHEDPLK VSVEPFFEWV 

       190        200        210        220        230        240 
IDRTGFAGGQ PVLKGALFTD DLTPFIERKL FTVNTGHAVT AYVGYQRGLK TVKEAIGHPE 

       250        260        270        280        290        300 
IRRVVYDALS ETGEYLVKAY GFKQSEHEQY MKKIIGRFEN EYITDDVTRV ARSPLRKLGA 

       310        320        330        340        350        360 
NDRLVGPAKK IKEPNALAEG IAAALRFDYQ DDPEAVELQK LIAEKGTSRV LQDICGIQLH 

       370 
EPLHGIVLKK LNQ

A7Z1E8 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools