[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Fulton B., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R.; Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: D-mannitol 1-phosphate + NAD⁺ = D-fructose 6-phosphate + NADH.
SIMILARITY: Belongs to the mannitol dehydrogenase family.

Copyright

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Cross-references

Sequence databases

EMBL

CP000783; ABU79064.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_001439900.1; -.

3D structure databases

ModBase

A7MNE5.

Ontologies

GO:0008926;	Molecular function: mannitol-1-phosphate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00196; -; 1.
PBIL [Tree]

InterPro

IPR013328; DHase_multihelical.
IPR013118; Mannitol_DHase_C.
IPR000669; Mannitol_DHase_core.
IPR013131; Mannitol_DHase_N.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.

Pfam

PF01232; Mannitol_dh; 1.
PF08125; Mannitol_dh_C; 1.
Pfam graphical view of domain structure.

PRINTS

PR00084; MTLDHDRGNASE.

PROSITE

PS00974; MANNITOL_DHGENASE; 1.

BLOCKS

A7MNE5.

Genome annotation databases

GeneID

5548780; -.

GenomeReviews

CP000783_GR; ESA_03878.

KEGG

esa:ESA_03878; -.

CMR

A7MNE5; ESA_03878.

Other

ProtoNet

A7MNE5.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; NAD; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 382`	`382`	`Mannitol-1-phosphate 5-dehydrogenase.`	`PRO_1000011797`
`NP_BIND`	`3 14`	`12`	`NAD (By similarity).`

Sequence information

Length: 382 AA [This is the length of the unprocessed precursor]

Molecular weight: 41147 Da [This is the MW of the unprocessed precursor]

CRC64: 422F867465D14896 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKALHFGAGN IGRGFIGKLL ADAGVGLTFA DVNQTVLDAL NARHSYQVRV VGEQEQIDTV 

        70         80         90        100        110        120 
SGVDAVNSTS EDVVTLIATV DLVTTAVGPV VLERIAPAIA KGLVLRKAQG NERPLNIIAC 

       130        140        150        160        170        180 
ENMVRGTSQL KTHVFNALEE GDKAWVESHI GFVDSAVDRI VPPSASAAHD PLEVTVETFS 

       190        200        210        220        230        240 
EWIVDKTQFK GELPTIAGME LTDNLMAFVE RKLFTLNTGH AITAYLGKQA GHQTIRDAIL 

       250        260        270        280        290        300 
DEKIRLVVRG AMEESGAVLI KRYGFDDAKH AAYIEKILSR FENPYLKDDV ERVGRQPLRK 

       310        320        330        340        350        360 
LSAGDRLIKP LLGTLEYGLP HQNLVLGIAA AMHFRSEDDP QAQELAQLIA DKGPQAALAQ 

       370        380 
ISGLDANSDV VASAVNAYNA TA

A7MNE5 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools