NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., Nelson K.E.;
"Complete genome sequence of Campylobacter hominis ATCC BAA-381, a commensal isolated from the human gastrointestinal tract.";
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.

Comments

FUNCTION: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions (By similarity).
CATALYTIC ACTIVITY: NTP + H₂O = NDP + phosphate.
COFACTOR: Divalent cations (By similarity).
SUBUNIT: Homodimer (By similarity).
SIMILARITY: Belongs to the HAM1 NTPase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000776; ABS52222.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_001405631.1; -.

3D structure databases

ModBase

A7HZE0.

Ontologies

GO:0017111;	Molecular function: nucleoside-triphosphatase activity (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_01405; -; 1.
PBIL [Tree]

InterPro

IPR002637; Ham1p_like.
Graphical view of domain structure.

PANTHER

PTHR11067; Ham1p_like; 1.

Pfam

PF01725; Ham1p_like; 1.
Pfam graphical view of domain structure.

BLOCKS

A7HZE0.

Genome annotation databases

GeneID

5408577; -.

GenomeReviews

CP000776_GR; CHAB381_0009.

KEGG

cha:CHAB381_0009; -.

NMPDR

fig|360107.5.peg.9; -.

CMR

A7HZE0; CHAB381_0009.

Other

ProtoNet

A7HZE0.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Hydrolase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 206`	`206`		`Nucleoside-triphosphatase.`	`PRO_1000068412`

Sequence information

Length: 206 AA [This is the length of the unprocessed precursor]

Molecular weight: 23253 Da [This is the MW of the unprocessed precursor]

CRC64: B54A3E94DEBC7387 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKIILATSNK DKVKEIKAFY KNYEIYALNE IMQPFEIKET GSSFKENALI KVNAVYKKLE 

        70         80         90        100        110        120 
EMKLENEFMA LSDDSGICVD ILGGAPGIYS ARYSNDMVIH PTDESNRAKL ISKLHKKNVK 

       130        140        150        160        170        180 
TSPAHYTACI ALSCKSGNFT THGFMHGRVI DEERGNNGFG YDFMFIANGF SKTIGELDEN 

       190        200 
TKLKISHRSK GLFLMSKILK ILNRSF

A7HZE0 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools