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UniProtKB/Swiss-Prot entry A7GKE0

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DDL_BACCN
Primary accession number A7GKE0
Secondary accession numbers None
Integrated into Swiss-Prot on May 20, 2008
Sequence was last modified on September 11, 2007 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 13)
Name and origin of the protein
Protein name D-alanine--D-alanine ligase
Synonyms EC 6.3.2.4
D-alanylalanine synthetase
D-Ala-D-Ala ligase
Gene name
Name: ddl
OrderedLocusNames: Bcer98_0232
From
Bacillus cereus subsp. cytotoxis (strain NVH 391-98) [TaxID: 315749] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus; Bacillus cereus group.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1016/j.cbi.2007.03.003; PubMed=17434157 [NCBI, ExPASy, EBI, Israel, Japan]
Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B., Dossat C., Land M.L., Broussolle V., Brillard J., Guinebretiere M.-H., Sanchis V., Nguen-the C., Lereclus D., Richardson P., Wincker P., Weissenbach J., Ehrlich S.D., Sorokin A.;
"Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity.";
Chem. Biol. Interact. 171:236-249(2008).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000764; ABS20598.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001373593.1; -.
3D structure databases
ModBase A7GKE0.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0008716; Molecular function: D-alanine-D-alanine ligase activity (inferred from electronic annotation from HAMAP).
GO:0009252; Biological process: peptidoglycan biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00047; -; 1.
PBIL [Tree]
InterPro IPR011761; ATP-grasp.
IPR013816; ATP_grasp_subdomain_2.
IPR000291; D-Ala_lig_Van_CS.
IPR005905; D_ala_D_ala.
IPR011095; Dala_Dala_lig_C.
IPR011127; Dala_Dala_lig_N.
IPR013817; Pre-ATP_grasp.
Graphical view of domain structure.
Gene3D G3DSA:3.30.470.20; ATP_grasp_subdomain_2; 2.
G3DSA:3.40.50.20; Pre-ATP_grasp; 1.
Pfam PF07478; Dala_Dala_lig_C; 1.
PF01820; Dala_Dala_lig_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01205; D_ala_D_alaTIGR; 1.
PROSITE PS50975; ATP_GRASP; 1.
PS00843; DALA_DALA_LIGASE_1; 1.
PS00844; DALA_DALA_LIGASE_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS A7GKE0.
Genome annotation databases
GeneID 5344614; -.
GenomeReviews CP000764_GR; Bcer98_0232.
KEGG bcy:Bcer98_0232; -.
CMR A7GKE0; Bcer98_0232.
Other
ProtoNet A7GKE0.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Cell shape; Cell wall biogenesis/degradation; Complete proteome; Cytoplasm; Ligase; Magnesium; Manganese; Metal-binding; Nucleotide-binding; Peptidoglycan synthesis.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   362  362     D-alanine--D-alanine ligase. PRO_1000074762
DOMAIN   141   346  206     ATP-grasp. 
NP_BIND   174   229  56     ATP (By similarity). 
METAL   300   300        Magnesium or manganese 1 (By similarity). 
METAL   313   313        Magnesium or manganese 1 (By similarity). 
METAL   313   313        Magnesium or manganese 2 (By similarity). 
METAL   315   315        Magnesium or manganese 2 (By similarity). 
Sequence information
Length: 362 AA [This is the length of the unprocessed precursor] Molecular weight: 40270 Da [This is the MW of the unprocessed precursor] CRC64: 3F49BC1B3A32569B [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTKIKLGLLY GGKSAEHQVS LQTALAAIKA LNQEKFEIHP IYITEQGQWM RGERIEGEVT 

        70         80         90        100        110        120 
SVQALQMSGE ANAISPVSLS TEIIPAPASK QEEAIDVIFP LLHGPNGEDG TVQGLLELMN 

       130        140        150        160        170        180 
IPYVGNGVLA SAAGMDKVVM KNIFAEAGLN QAKYTSFVRS VWEKNREEAY EKVEEALGYP 

       190        200        210        220        230        240 
CFVKPANLGS SVGINKCKDR EELEKAFEEA FQFDRKIIVE ENIIGREVEV GVLGNDDPKC 

       250        260        270        280        290        300 
SVVGEIVPKK EFYDYKSKYI DGDTALIIPA EITEEETATI QRDAIRAFQA LDGAGLTRAD 

       310        320        330        340        350        360 
FFLTKDGEVY INEVNTMPGF TPFSMFPLLW QHTGLSYPEL IEELIRLAIE RHKEKQKIKY 


TI
A7GKE0 in FASTA format

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