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UniProtKB/Swiss-Prot entry A6VLU1

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ILVC_ACTSZ
Primary accession number A6VLU1
Secondary accession numbers None
Integrated into Swiss-Prot on February 26, 2008
Sequence was last modified on August 21, 2007 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 10)
Name and origin of the protein
Protein name Ketol-acid reductoisomerase
Synonyms EC 1.1.1.86
Acetohydroxy-acid isomeroreductase
Alpha-keto-beta-hydroxylacil reductoisomerase
Gene name
Name: ilvC
OrderedLocusNames: Asuc_0563
From
Actinobacillus succinogenes (strain ATCC 55618 / 130Z) [TaxID: 339671] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Actinobacillus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Lowry S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Vieille C., Richardson P.;
"Complete sequence of Actinobacillus succinogenes 130Z.";
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000746; ABR73938.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001343873.1; -.
3D structure databases
ModBase A6VLU1.
Ontologies
GO
GO:0004455; Molecular function: ketol-acid reductoisomerase activity (inferred from electronic annotation from HAMAP).
GO:0009097; Biological process: isoleucine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0009099; Biological process: valine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00435; -; 1.
PBIL [Tree]
InterPro IPR013023; AcH_isomrdctse.
IPR000506; AcH_isomrdctse_C.
IPR013328; DHase_multihelical.
IPR013116; IlvN.
IPR014359; KetolA_reductoisomerase_bac.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.
PANTHER PTHR21371; AcH_isomrdctse; 1.
Pfam PF01450; IlvC; 1.
PF07991; IlvN; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000116; IlvC_gammaproteo; 1.
TIGRFAMs TIGR00465; ilvC; 1.
BLOCKS A6VLU1.
Genome annotation databases
GeneID 5348214; -.
GenomeReviews CP000746_GR; Asuc_0563.
KEGG asu:Asuc_0563; -.
CMR A6VLU1; Asuc_0563.
Other
ProtoNet A6VLU1.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   493  493     Ketol-acid reductoisomerase. PRO_1000072318
ACT_SITE   132   132        Potential. 
Sequence information
Length: 493 AA [This is the length of the unprocessed precursor] Molecular weight: 54331 Da [This is the MW of the unprocessed precursor] CRC64: 30705DD722BC06D3 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSNYFNTLNL REKLDQLGRC RFMDRSEFSD GCNFLKGKKI VIVGCGAQGL NQGLNMRDSG 

        70         80         90        100        110        120 
LDISYALRKA AIEEKRPSFQ RATENGFKVG TYEELIPTAD LVINLTPDKQ HSKVVSDVMP 

       130        140        150        160        170        180 
LMKQGAAFGY SHGFNIVEVG EQIREDITVV MSAPKCPGTE VREEYKRGFG VPTLIAVHPA 

       190        200        210        220        230        240 
NDPKGEGMAI AKAWASATGG DRAGVLESSF VAEVKSDLMG EQTILCGMLQ AGSIVCYDKL 

       250        260        270        280        290        300 
IADGKDPAYA GKLIQYGWET ITEALKQGGI TLMMDRLSNA AKLRAFELSE QIKEKLGFLY 

       310        320        330        340        350        360 
LKHMDDIISG EFSRVMMEDW ANGDKDLLAW REATGKTAFE NAPKADGIKI SEQEYFDNGV 

       370        380        390        400        410        420 
LMVAMVKAGV EMAFDAMVAS GIYEESAYYE SLHELPLIAN TIARKRLYEM NVVISDTAEY 

       430        440        450        460        470        480 
GNYLFSNVAT PILAKEIIPA LQKGDLGEPT PAVDIDNVTL RDVNDEIRNH PVELIGLELR 

       490 
GYMTDMKRIS SQG
A6VLU1 in FASTA format

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