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UniProtKB/Swiss-Prot entry A6KXU3

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DDL_BACV8
Primary accession number A6KXU3
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on July 24, 2007 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 14)
Name and origin of the protein
Protein name D-alanine--D-alanine ligase
Synonyms EC 6.3.2.4
D-alanylalanine synthetase
D-Ala-D-Ala ligase
Gene name
Name: ddl
OrderedLocusNames: BVU_0547
From
Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154) [TaxID: 435590] [HAMAP proteome]
Taxonomy Bacteria; Bacteroidetes; Bacteroidetes (class); Bacteroidales; Bacteroidaceae; Bacteroides.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1371/journal.pbio.0050156; PubMed=17579514 [NCBI, ExPASy, EBI, Israel, Japan]
Xu J., Mahowald M.A., Ley R.E., Lozupone C.A., Hamady M., Martens E.C., Henrissat B., Coutinho P.M., Minx P., Latreille P., Cordum H., Van Brunt A., Kim K., Fulton R.S., Fulton L.A., Clifton S.W., Wilson R.K., Knight R.D., Gordon J.I.;
"Evolution of symbiotic bacteria in the distal human intestine.";
PLoS Biol. 5:1574-1586(2007).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000139; ABR38257.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001297879.1; -.
3D structure databases
ModBase A6KXU3.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0008716; Molecular function: D-alanine-D-alanine ligase activity (inferred from electronic annotation from HAMAP).
GO:0009252; Biological process: peptidoglycan biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00047; -; 1.
PBIL [Tree]
InterPro IPR011761; ATP-grasp.
IPR000291; D-Ala_lig_Van_CS.
IPR005905; D_ala_D_ala.
IPR011095; Dala_Dala_lig_C.
IPR011127; Dala_Dala_lig_N.
Graphical view of domain structure.
Pfam PF07478; Dala_Dala_lig_C; 1.
PF01820; Dala_Dala_lig_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01205; D_ala_D_alaTIGR; 1.
PROSITE PS50975; ATP_GRASP; 1.
PS00843; DALA_DALA_LIGASE_1; 1.
PS00844; DALA_DALA_LIGASE_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS A6KXU3.
Genome annotation databases
GeneID 5301516; -.
GenomeReviews CP000139_GR; BVU_0547.
KEGG bvu:BVU_0547; -.
NMPDR fig|435590.6.peg.524; -.
CMR A6KXU3; BVU_0547.
Other
ProtoNet A6KXU3.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Cell shape; Cell wall biogenesis/degradation; Complete proteome; Cytoplasm; Ligase; Magnesium; Manganese; Metal-binding; Nucleotide-binding; Peptidoglycan synthesis.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   324  324     D-alanine--D-alanine ligase. PRO_1000030427
DOMAIN   121   321  201     ATP-grasp. 
NP_BIND   149   204  56     ATP (By similarity). 
METAL   275   275        Magnesium or manganese 1 (By similarity). 
METAL   288   288        Magnesium or manganese 1 (By similarity). 
METAL   288   288        Magnesium or manganese 2 (By similarity). 
METAL   290   290        Magnesium or manganese 2 (By similarity). 
Sequence information
Length: 324 AA [This is the length of the unprocessed precursor] Molecular weight: 36065 Da [This is the MW of the unprocessed precursor] CRC64: 36C9C8C02F858E54 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKRTIAIVAG GDSSELVVSL RSAQGLYSFI DKERYNLYIV EMEGHRWEVV LPDGSKTPID 

        70         80         90        100        110        120 
RNDFSFMENG EKKQFDFAYI TIHGTPGENG ILQGYFDLLG IPYSSCNVLV SAMTFNKFTC 

       130        140        150        160        170        180 
NQYLKGFGIR VAESLILRKG FEITDEEVIN KIGLPCFIKP NAGGSSFGVT KVKTKEDIQP 

       190        200        210        220        230        240 
AIEKAFEESD EVMIEAFMKG TEITCGCYKT SDKEVVFPIT EVVSANEFFD YGAKYNGESQ 

       250        260        270        280        290        300 
EITPARLPED TAERVRLLTS AIYDILGCSG LIRIDYIITE GEKVNLLEIN TTPGMTATSF 

       310        320 
IPQQVRAAGL DIKDVMTDII ENKF
A6KXU3 in FASTA format

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