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UniProtKB/Swiss-Prot entry A4YJV4


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HIS4_BRASO
Primary accession number A4YJV4
Secondary accession numbers None
Integrated into Swiss-Prot on February 5, 2008
Sequence was last modified on May 29, 2007 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 10)
Name and origin of the protein
Protein name 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Synonyms EC 5.3.1.16
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Gene name
Name: hisA
OrderedLocusNames: BRADO0215
From
Bradyrhizobium sp. (strain ORS278) [TaxID: 114615] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1139548; PubMed=17540897 [NCBI, ExPASy, EBI, Israel, Japan]
Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.-C., Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L., Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z., Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.-S., Saunders E., Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G., Emerich D., Vermeglio A., Medigue C., Sadowsky M.;
"Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia.";
Science 316:1307-1312(2007).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CU234118; CAL74180.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001202430.1; -.
3D structure databases
ModBase A4YJV4.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0003949; Molecular function: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity (inferred from electronic annotation from HAMAP).
GO:0000105; Biological process: histidine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01014; -; 1.
PBIL [Tree]
InterPro IPR006063; His4.
IPR006062; His_biosynth.
Graphical view of domain structure.
Pfam PF00977; His_biosynth; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00007; His4; 1.
Genome annotation databases
GeneID 5121086; -.
GenomeReviews CU234118_GR; BRADO0215.
KEGG bra:BRADO0215; -.
CMR A4YJV4; BRADO0215.
Other
ProtoNet A4YJV4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Cytoplasm; Histidine biosynthesis; Isomerase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   244  244     1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. PRO_1000063188
ACT_SITE   8     8        Proton acceptor (By similarity). 
ACT_SITE   129   129        Proton donor (By similarity). 
Sequence information
Length: 244 AA [This is the length of the unprocessed precursor] Molecular weight: 25576 Da [This is the MW of the unprocessed precursor] CRC64: 874F7904C7F22AA4 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MILFPAIDLK NGQCVRLEQG DMARATVFNL DPAAQAKSFA DQGFEYLHVV DLDGAFAGKP 

        70         80         90        100        110        120 
MNAQAVEAML KIVKMPVQLG GGIRDLKTVE AWLGKGITRV IIGTAAVRDP ELVKMAAKAF 

       130        140        150        160        170        180 
PGRVAVGLDA RDGKVAVEGW AETSEVTALD IAKRFEDAGV AAIIFTDIAR DGLLKGLNLD 

       190        200        210        220        230        240 
ATIALGDAIS IPVIASGGLA SIEDVKAMLT PRARKLEGAI AGRALYDGRL DPAEALALIR 


AISG 

A4YJV4 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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