ID   DNAE2_PSEMY             Reviewed;        1026 AA.
AC   A4XTN0;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   25-NOV-2008, entry version 12.
DE   RecName: Full=Error-prone DNA polymerase;
DE            EC=2.7.7.7;
GN   Name=dnaE2; OrderedLocusNames=Pmen_1934;
OS   Pseudomonas mendocina (strain ymp).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=399739;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Detter J.C.,
RA   Bruce D., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Mikhailova N., Hersman L., Dubois J., Maurice P.,
RA   Richardson P.;
RT   "Complete sequence of Pseudomonas mendocina ymp.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: DNA polymerase involved in damage-induced mutagenesis
CC       and translesion synthesis (TLS). It is not the major replicative
CC       DNA polymerase (By similarity).
CC   -!- CATALYTIC ACTIVITY: Deoxynucleoside triphosphate + DNA(n) =
CC       diphosphate + DNA(n+1).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Probable).
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-C family. DnaE2
CC       subfamily.
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DR   EMBL; CP000680; ABP84696.1; -; Genomic_DNA.
DR   RefSeq; YP_001187428.1; -.
DR   GeneID; 5110062; -.
DR   GenomeReviews; CP000680_GR; Pmen_1934.
DR   KEGG; pmy:Pmen_1934; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:HAMAP.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:HAMAP.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   GO; GO:0045020; P:error-prone DNA repair; IEA:HAMAP.
DR   HAMAP; MF_01902; -; 1.
DR   InterPro; IPR011708; DNA_pol3_alpha.
DR   InterPro; IPR004365; NA_bd_OB_tRNA-helicase.
DR   InterPro; IPR004013; PHP_C.
DR   InterPro; IPR003141; PHP_N.
DR   InterPro; IPR004805; PolC_alpha.
DR   Pfam; PF07733; DNA_pol3_alpha; 1.
DR   Pfam; PF02811; PHP; 1.
DR   Pfam; PF01336; tRNA_anti; 1.
DR   SMART; SM00481; POLIIIAc; 1.
DR   TIGRFAMs; TIGR00594; polc; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; DNA damage; DNA repair; DNA replication;
KW   DNA-directed DNA polymerase; Nucleotidyltransferase; Transferase.
FT   CHAIN         1   1026       Error-prone DNA polymerase.
FT                                /FTId=PRO_1000070593.
SQ   SEQUENCE   1026 AA;  115403 MW;  CAF82455F48121EC CRC64;
     MTPDYAELHC LSNFSFQRGA SSARELFERA ARLGYRALAI TDECTLAGIV RAWQAARETG
     LALIVGSEMP IEGGPKLVLL AEDLAGYQAL CRLITVARRR AEKGRYRLLR EDFDTPLAGL
     LAIWLAEPQA SDSEGAWLRQ RFADRLWLGI ELHRGADDAA RLRQLQALAA RLQIPALACG
     DVHMHARGRR ALQDCMTAIR QHLPVAEAGA WLFPNGERHL RRREELAELY PQELLDETLR
     VAARCHFELD QLKYQYPHEL VPAGHDASSW LRHRVEEGLR WRWPDGASTK VRTQVEHELQ
     LITELKYESY FLTVHDIVSW ARKQHILCQG RGSAANSTVC FALGITELNP DNSGSRLLFE
     RFLSRERNEP PDIDVDFEHE RREEVIQYVF RRYGRQRAAL TAVASTYHGA GALRDVAKAL
     GLPPDQVGAL ADCCGRWSDH MPDAERLREA GFDPDSPSLH RILTLAGELI GFPRHLSQHP
     GGFVISEHPL QTLVPVENAS MAERTVIQWD KDDLDLVGLL KVDILALGML SALRRCFALI
     ERYRGTRWTL ASLPQEDAAT YAMISRADTV GVFQIESRAQ MAMLPRLRPK TFYDLVIQVA
     IVRPGPIQGD MVHPYLRRRN DEEPVEYPSD ELRPVFARTL GVPLFQEQVM ELAMVAADYS
     PGEADELRRS MAAWKRHGGL EPHRQRLTSR MLEKGYTAEF TARIFRQIEG FGSYGFPESH
     AASFALLTYA SCWLKCHEPA AYACALVNSW PMGFYSPDQV LQDARRHGIE VRPADVRHSA
     WDCSLEPSDG EQPAIRLGLR LLRGFREEDA LRIEATRQAA PFTDVDDLCR RATLDARARE
     CLADAGALRG LAGNRYRARW AVAGVEPQLP LFAGHSSREE PVALPRPTVG EDLLTDYATF
     GTTLGPHPLA LLRERLRAKR CRSSHELCTV EHGRPVSVAG LVIGRQRPQT ASGVIFVTLE
     DEFGMVNVVV WHDLAERQRR VLLQSRLLRI DGHLESADGV RHVIAGRLTD LSPLLTGLDV
     KSRDFH
//