NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0609650104; PubMed=17372208 [NCBI, ExPASy, EBI, Israel, Japan]
Feng L., Wang W., Cheng J., Ren Y., Zhao G., Gao C., Tang Y., Liu X., Han W., Peng X., Liu R., Wang L.;
"Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir.";
Proc. Natl. Acad. Sci. U.S.A. 104:5602-5607(2007).

Comments

CATALYTIC ACTIVITY: D-mannitol 1-phosphate + NAD⁺ = D-fructose 6-phosphate + NADH.
SIMILARITY: Belongs to the mannitol dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000557; ABO67204.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_001125949.1; -.

3D structure databases

ModBase

A4IPF0.

Ontologies

GO:0008926;	Molecular function: mannitol-1-phosphate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00196; -; 1.
PBIL [Tree]

InterPro

IPR013328; DHase_multihelical.
IPR013118; Mannitol_DHase_C.
IPR000669; Mannitol_DHase_core.
IPR013131; Mannitol_DHase_N.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.

Pfam

PF01232; Mannitol_dh; 1.
PF08125; Mannitol_dh_C; 1.
Pfam graphical view of domain structure.

PRINTS

PR00084; MTLDHDRGNASE.

PROSITE

PS00974; MANNITOL_DHGENASE; 1.

BLOCKS

A4IPF0.

Genome annotation databases

GeneID

4966777; -.

GenomeReviews

CP000557_GR; GTNG_1844.

KEGG

gtn:GTNG_1844; -.

NMPDR

fig|420246.5.peg.1775; -.

CMR

A4IPF0; GTNG_1844.

Other

ProtoNet

A4IPF0.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; NAD; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 385`	`385`	`Mannitol-1-phosphate 5-dehydrogenase.`	`PRO_1000011800`
`NP_BIND`	`3 14`	`12`	`NAD (By similarity).`

Sequence information

Length: 385 AA [This is the length of the unprocessed precursor]

Molecular weight: 42313 Da [This is the MW of the unprocessed precursor]

CRC64: 7C168104B1AFA86D [This is a checksum on the sequence]

        10         20         30         40         50         60 
MRAVHFGAGN IGRGFIGSLL AASGYDVVFV DVNEQIVRLL KERGEYRVII AGERQEEQWV 

        70         80         90        100        110        120 
RGVSALNSQT ERDDVIEAIA SADLVTTAVG PHILPVIAPV IAAGLERRFT VHQKPLHVIA 

       130        140        150        160        170        180 
CENMIGGTET LKQHVVTHLS EAGRQLVEEC VGFLNCAVDR IVPNQTNDDP LAVTVEPFFE 

       190        200        210        220        230        240 
WAIETKNTIG AVPPIQGAHF VADLGPYIER KLFTVNTGHA LAAYLGYQKQ YRTVQEAMKD 

       250        260        270        280        290        300 
SGIRESVEQA LRESGAVLVK KHGWDEQEHR SYIETTIGRF TNPSLSDDIV RVARSPIRKL 

       310        320        330        340        350        360 
GPNDRLVAPA VQYYTLFERV PSGLVKGIAA LLLFDETGDA EATALQQTIE QSGVEGALVQ 

       370        380 
YAGLDNSHPL VVAVKEEYKK MQKEQ

A4IPF0 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools