ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry A3N1U6

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name MDH_ACTP2
Primary accession number A3N1U6
Secondary accession numbers None
Integrated into Swiss-Prot on July 10, 2007
Sequence was last modified on April 3, 2007 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 11)
Name and origin of the protein
Protein name Malate dehydrogenase
Synonym EC 1.1.1.37
Gene name
Name: mdh
OrderedLocusNames: APL_1296
From
Actinobacillus pleuropneumoniae serotype 5b (strain L20) [TaxID: 416269] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Actinobacillus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.01845-07; PubMed=18065534 [NCBI, ExPASy, EBI, Israel, Japan]
Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M., Nash J.H.E.;
"The complete genome sequence of Actinobacillus pleuropneumoniae L20 (serotype 5b).";
J. Bacteriol. 190:1495-1496(2008).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000569; ABN74382.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001053987.1; -.
3D structure databases
ModBase A3N1U6.
Ontologies
GO
GO:0030060; Molecular function: L-malate dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0006099; Biological process: tricarboxylic acid cycle (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01516; -; 1.
PBIL [Tree]
InterPro IPR001557; L-lactate/malate_DHase.
IPR001236; Lactate/malate_DHase.
IPR015955; Lactate_DHase/Glyco_Ohase_4_C.
IPR001252; Malate_DHase_AS.
IPR010097; Malate_DHase_NAD-dep_euk_g_bac.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.90.110.10; lact_mal_DH; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR11540:SF1; MDH_euk_g_bac; 1.
Pfam PF02866; Ldh_1_C; 1.
PF00056; Ldh_1_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000102; Lac_mal_DH; 1.
TIGRFAMs TIGR01772; MDH_euk_gproteo; 1.
PROSITE PS00068; MDH; FALSE_NEG.
BLOCKS A3N1U6.
Genome annotation databases
GeneID 4850462; -.
GenomeReviews CP000569_GR; APL_1296.
KEGG apl:APL_1296; -.
CMR A3N1U6; APL_1296.
Other
ProtoNet A3N1U6.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase; Tricarboxylic acid cycle.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   317  317     Malate dehydrogenase. PRO_0000294291
NP_BIND   7    13  7     NAD (By similarity). 
NP_BIND   117   119  3     NAD (By similarity). 
ACT_SITE   177   177        Proton acceptor (By similarity). 
BINDING   34    34        NAD (By similarity). 
BINDING   81    81        Substrate (By similarity). 
BINDING   87    87        Substrate (By similarity). 
BINDING   94    94        NAD (By similarity). 
BINDING   119   119        Substrate (By similarity). 
BINDING   153   153        Substrate (By similarity). 
BINDING   231   231        NAD (By similarity). 
Sequence information
Length: 317 AA [This is the length of the unprocessed precursor] Molecular weight: 33347 Da [This is the MW of the unprocessed precursor] CRC64: 0108DFF580351B35 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKVALLGAAG GIGQTLALLL KLRLPVGTDL ALYDISPVTP GIAVDISHIP TSVSAVGYSG 

        70         80         90        100        110        120 
EDPSEALKGA NLVIITAGVA RKPGMTRADL FNINADIVKN LVEKVAEVCP KACIGIVTNP 

       130        140        150        160        170        180 
VNTLVPIAAE VLRKAGVYDK RKLFGVTTLD VVRAKTFTSE LKEKHVETVK VPVIGGHSGP 

       190        200        210        220        230        240 
TILPLLSQAL SEGLPLSFTQ EEIEALTYRI QNAGTEVVEA KAGGGSATLS MAESGARFAV 

       250        260        270        280        290        300 
AVFKALLGED CVRYAYVESK EGSGYPEFFA HPVRFGLTGV EELLPIGKLS EYEQAKLGEL 

       310 
KPVLEADIAL GKNFVNP
A3N1U6 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ch flag SIB Switzerland Mirror sites: Australia Brazil Canada China Korea
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!