NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.;
"Complete sequence of Acidovorax avenae subsp. citrulli AAC00-1.";
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.

Comments

FUNCTION: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions (By similarity).
CATALYTIC ACTIVITY: NTP + H₂O = NDP + phosphate.
COFACTOR: Divalent cations (By similarity).
SUBUNIT: Homodimer (By similarity).
SIMILARITY: Belongs to the HAM1 NTPase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000512; ABM34129.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_971903.1; -.

3D structure databases

ModBase

A1TT41.

Ontologies

GO:0017111;	Molecular function: nucleoside-triphosphatase activity (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_01405; -; 1.
PBIL [Tree]

InterPro

IPR002637; Ham1p_like.
Graphical view of domain structure.

PANTHER

PTHR11067; Ham1p_like; 1.

Pfam

PF01725; Ham1p_like; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR00042; Ham1p_like; 1.

BLOCKS

A1TT41.

Genome annotation databases

GeneID

4668547; -.

GenomeReviews

CP000512_GR; Aave_3578.

KEGG

aav:Aave_3578; -.

CMR

A1TT41; Aave_3578.

Other

ProtoNet

A1TT41.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Hydrolase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 199`	`199`		`Nucleoside-triphosphatase.`	`PRO_1000068405`

Sequence information

Length: 199 AA [This is the length of the unprocessed precursor]

Molecular weight: 21504 Da [This is the MW of the unprocessed precursor]

CRC64: ACDC09B2EE46FD21 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKLVLASNNR GKLAELQSMF SPLGVELVRQ ADLGVGEADE PFHTFVENAL AKARFAAEHT 

        70         80         90        100        110        120 
GLPALADDAG LCVDAFGGQP GVQTAYYATR FGYEKGDANN VRALLEQMRG VASRRAAMVS 

       130        140        150        160        170        180 
TLVAVRSPDD PEPLIAVGRV VGEIATEPRG DGGFGFDPVM FIPEFGKTFA ELPVEVKNAH 

       190 
SHRGRSAQQM LALMRERWF

A1TT41 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools