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UniProtKB/Swiss-Prot entry A1R7J5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DDL_ARTAT
Primary accession number A1R7J5
Secondary accession numbers None
Integrated into Swiss-Prot on June 10, 2008
Sequence was last modified on February 6, 2007 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 20)
Name and origin of the protein
Protein name D-alanine--D-alanine ligase
Synonyms EC 6.3.2.4
D-alanylalanine synthetase
D-Ala-D-Ala ligase
Gene name
Name: ddl
OrderedLocusNames: AAur_2481
From
Arthrobacter aurescens (strain TC1) [TaxID: 290340] [HAMAP proteome]
Taxonomy Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Micrococcineae; Micrococcaceae; Arthrobacter.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1371/journal.pgen.0020214; PubMed=17194220 [NCBI, ExPASy, EBI, Israel, Japan]
Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J.;
"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1.";
PLoS Genet. 2:2094-2106(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000474; ABM07506.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_948207.1; -.
3D structure databases
ModBase A1R7J5.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0008716; Molecular function: D-alanine-D-alanine ligase activity (inferred from electronic annotation from HAMAP).
GO:0009252; Biological process: peptidoglycan biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00047; -; 1.
PBIL [Tree]
InterPro IPR011761; ATP-grasp.
IPR013816; ATP_grasp_subdomain_2.
IPR000291; D-Ala_lig_Van_CS.
IPR005905; D_ala_D_ala.
IPR011095; Dala_Dala_lig_C.
IPR011127; Dala_Dala_lig_N.
IPR013817; Pre-ATP_grasp.
Graphical view of domain structure.
Gene3D G3DSA:3.30.470.20; ATP_grasp_subdomain_2; 1.
G3DSA:3.40.50.20; Pre-ATP_grasp; 1.
Pfam PF07478; Dala_Dala_lig_C; 1.
PF01820; Dala_Dala_lig_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01205; D_ala_D_alaTIGR; 1.
PROSITE PS50975; ATP_GRASP; 1.
PS00843; DALA_DALA_LIGASE_1; 1.
PS00844; DALA_DALA_LIGASE_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS A1R7J5.
Genome annotation databases
GeneID 4640348; -.
GenomeReviews CP000474_GR; AAur_2481.
KEGG aau:AAur_2481; -.
TIGR AAur_2481; -.
Other
ProtoNet A1R7J5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Cell shape; Cell wall biogenesis/degradation; Complete proteome; Cytoplasm; Ligase; Magnesium; Manganese; Metal-binding; Nucleotide-binding; Peptidoglycan synthesis.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   378  378     D-alanine--D-alanine ligase. PRO_0000341053
DOMAIN   157   368  212     ATP-grasp. 
NP_BIND   189   244  56     ATP (By similarity). 
METAL   322   322        Magnesium or manganese 1 (By similarity). 
METAL   335   335        Magnesium or manganese 1 (By similarity). 
METAL   335   335        Magnesium or manganese 2 (By similarity). 
METAL   337   337        Magnesium or manganese 2 (By similarity). 
Sequence information
Length: 378 AA [This is the length of the unprocessed precursor] Molecular weight: 39981 Da [This is the MW of the unprocessed precursor] CRC64: 912B80574B38828F [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MVTDHSTPVT GRPRVAILFG GRSSEHAVSC VTAAGVMGAI DKNKYEVIPI GIAKSGQWVL 

        70         80         90        100        110        120 
ASGDTSEWSL SSAALPEVAP SGRTVTLAEV GGEHQLIVTE PNAVPQELGS VDVVFPLLHG 

       130        140        150        160        170        180 
PWGEDGTIQG LLELSDTRYV GAGVLASAVG MDKHFMKVVF ESAGLSVGPY VAVTDREWST 

       190        200        210        220        230        240 
DAEAVRKRVD KLGFPVFVKP ARAGSSMGIS KVDSMEGLDA AIDEARRHDL KLVIEAGIVG 

       250        260        270        280        290        300 
REIECAVLQG RGTDAPRTSM PGEIAVAVGE HQFYDFAAKY VEDGAAALSC PADMPDEAIA 

       310        320        330        340        350        360 
RVRELAAVAF DAVGAEGLSR VDFFYTPAGE LIINEINTMP GFTPKSMYPQ MWAASGLAYG 

       370 
DLIDELIHLA LTRKTGLR
A1R7J5 in FASTA format

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