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UniProtKB/Swiss-Prot entry A1R2A8

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PURA_ARTAT
Primary accession number A1R2A8
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on February 6, 2007 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 17)
Name and origin of the protein
Protein name Adenylosuccinate synthetase
Synonyms EC 6.3.4.4
IMP--aspartate ligase
AdSS
AMPSase
Gene name
Name: purA
OrderedLocusNames: AAur_0563
From
Arthrobacter aurescens (strain TC1) [TaxID: 290340] [HAMAP proteome]
Taxonomy Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Micrococcineae; Micrococcaceae; Arthrobacter.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1371/journal.pgen.0020214; PubMed=17194220 [NCBI, ExPASy, EBI, Israel, Japan]
Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B., Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J.;
"Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1.";
PLoS Genet. 2:2094-2106(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000474; ABM06751.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_946370.1; -.
3D structure databases
ModBase A1R2A8.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004019; Molecular function: adenylosuccinate synthase activity (inferred from electronic annotation from HAMAP).
GO:0005525; Molecular function: GTP binding (inferred from electronic annotation from HAMAP).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from HAMAP).
GO:0006164; Biological process: purine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00011; -; 1.
PBIL [Tree]
InterPro IPR001114; AdlSucc_Synth.
Graphical view of domain structure.
PANTHER PTHR11846; Asucc_synthtase; 1.
Pfam PF00709; Adenylsucc_synt; 1.
Pfam graphical view of domain structure.
ProDom PD001188; Asucc_synthtase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00788; Adenylsucc_synt; 1.
SMART graphical view of domain structure.
TIGRFAMs TIGR00184; purA; 1.
PROSITE PS01266; ADENYLOSUCCIN_SYN_1; 1.
PS00513; ADENYLOSUCCIN_SYN_2; 1.
ProtoNet A1R2A8.
Genome annotation databases
GeneID 4639161; -.
GenomeReviews CP000474_GR; AAur_0563.
KEGG aau:AAur_0563; -.
TIGR AAur_0563; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; GTP-binding; Ligase; Magnesium; Metal-binding; Nucleotide-binding; Purine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   429  429     Adenylosuccinate synthetase. PRO_1000000776
NP_BIND   12    18  7     GTP (Potential). 
ACT_SITE   139   139        By similarity. 
ACT_SITE   146   146        By similarity. 
METAL   13    13        Magnesium (By similarity). 
METAL   40    40        Magnesium; via carbonyl oxygen (By similarity). 
Sequence information
Length: 429 AA [This is the length of the unprocessed precursor] Molecular weight: 46646 Da [This is the MW of the unprocessed precursor] CRC64: 03BEEE52F12A8991 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MPAIVIVGAQ WGDEGKGKAT DLLGGRVDYV VKPNGGNNAG HTVVVGGEKY ELKLLPAGIL 

        70         80         90        100        110        120 
SPNAIPIIGN GCVVNLEALF QEIDGLEARG ADTSRLRVSA NAHLVAPYHQ VLDKVTERFL 

       130        140        150        160        170        180 
GSRAIGTTGR GIGPAYMDKV ARLGIRVQDV FDESILRQKV EGSLRQKNEL LVKVYNRRDI 

       190        200        210        220        230        240 
IADEIVEYFL SFAERLRPLV IDSTLELNNA LDEGKVVLME GGQATFLDVD HGTYPFVTSS 

       250        260        270        280        290        300 
NPTAGGASVG SGIGPTRISR SIGIIKAYTT RVGAGPFPTE LFDEMGVYLQ KTGGEFGVNT 

       310        320        330        340        350        360 
GRPRRCGWYD AVLARHASRV NGFTDYFVTK LDVLTGIEQI PVCVAYDVDG VRHDEMPMTQ 

       370        380        390        400        410        420 
TEFHHAVPIF EYFDGWTEDI TGARTLEDLP ENARNYVLAL EKLSGTRFSA IGVGPDRDQT 


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A1R2A8 in FASTA format

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