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UniProtKB/Swiss-Prot entry A1K3T5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PYRC_AZOSB
Primary accession number A1K3T5
Secondary accession numbers None
Integrated into Swiss-Prot on March 18, 2008
Sequence was last modified on February 6, 2007 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 17)
Name and origin of the protein
Protein name Dihydroorotase
Synonyms DHOase
EC 3.5.2.3
Gene name
Name: pyrC
OrderedLocusNames: azo0873
From
Azoarcus sp. (strain BH72) [TaxID: 62928] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Rhodocyclales; Rhodocyclaceae; Azoarcus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nbt1243; PubMed=17057704 [NCBI, ExPASy, EBI, Israel, Japan]
Krause A., Ramakumar A., Bartels D., Battistoni F., Bekel T., Boch J., Boehm M., Friedrich F., Hurek T., Krause L., Linke B., McHardy A.C., Sarkar A., Schneiker S., Syed A.A., Thauer R., Vorhoelter F.-J., Weidner S., Puehler A., Reinhold-Hurek B., Kaiser O., Goesmann A.;
"Complete genome of the mutualistic, N2-fixing grass endophyte Azoarcus sp. strain BH72.";
Nat. Biotechnol. 24:1385-1391(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AM406670; CAL93490.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_932377.1; -.
3D structure databases
ModBase A1K3T5.
Ontologies
GO
GO:0004151; Molecular function: dihydroorotase activity (inferred from electronic annotation from HAMAP).
GO:0008270; Molecular function: zinc ion binding (inferred from electronic annotation from HAMAP).
GO:0006221; Biological process: pyrimidine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00219; -; 1.
PBIL [Tree]
InterPro IPR006680; Amidohydro_1.
IPR004721; DHOdimr.
IPR002195; Dihydroorotase_CS.
Graphical view of domain structure.
Pfam PF01979; Amidohydro_1; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF001237; DHOdimr; 1.
TIGRFAMs TIGR00856; pyrC_dimer; 1.
PROSITE PS00482; DIHYDROOROTASE_1; 1.
PS00483; DIHYDROOROTASE_2; 1.
BLOCKS A1K3T5.
Genome annotation databases
GeneID 4606619; -.
GenomeReviews AM406670_GR; azo0873.
KEGG azo:azo0873; -.
CMR A1K3T5; azo0873.
Other
ProtoNet A1K3T5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Hydrolase; Metal-binding; Pyrimidine biosynthesis; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   344  344     Dihydroorotase. PRO_0000325569
METAL   13    13        Zinc 1 (By similarity). 
METAL   15    15        Zinc 1 (By similarity). 
METAL   99    99        Zinc 1; via carbamate group (By similarity). 
METAL   99    99        Zinc 2; via carbamate group (By similarity). 
METAL   136   136        Zinc 2 (By similarity). 
METAL   174   174        Zinc 2 (By similarity). 
METAL   247   247        Zinc 1 (By similarity). 
MOD_RES   99    99        N6-carboxylysine (By similarity). 
Sequence information
Length: 344 AA [This is the length of the unprocessed precursor] Molecular weight: 37002 Da [This is the MW of the unprocessed precursor] CRC64: D7B70D3E29E5EDFA [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MQSITFTRPD DWHLHVRDGA ALAAVVPHTA ERFGRALIMP NLRPPVTTTA QALAYRDRIR 

        70         80         90        100        110        120 
AAVPAGLAFE PLMSLYLTDN TAPDEIERAR ASGAVIAAKL YPAGATTNSD AGVTAIDKIY 

       130        140        150        160        170        180 
PVLERMEACG LVLCVHGEVT GGEVDVFDRE RVFMEKILSP LVRRFPALKV VFEHITTAEA 

       190        200        210        220        230        240 
AQFVRAAGAN VAATVTAHHL LLNRNAIFAG GIRPHHYCLP VLKRETHRVA LVEAVTSGNP 

       250        260        270        280        290        300 
RFFLGTDSAP HARSTKEAAC GCAGCYTAHA GIELYAEVFD AAGALERLEA FASLNGPAFY 

       310        320        330        340 
GLAPNADKIT LVRESWSVPA GFPYLDDDPL VPLRAGESVG WRLA
A1K3T5 in FASTA format

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