ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry A1JTY5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name MAO1_YERE8
Primary accession number A1JTY5
Secondary accession numbers None
Integrated into Swiss-Prot on February 5, 2008
Sequence was last modified on February 6, 2007 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 17)
Name and origin of the protein
Protein name NAD-dependent malic enzyme
Synonyms NAD-ME
EC 1.1.1.38
Gene name
Name: sfcA
OrderedLocusNames: YE2794
From
Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081) [TaxID: 393305] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Yersinia.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1371/journal.pgen.0020206; PubMed=17173484 [NCBI, ExPASy, EBI, Israel, Japan]
Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L., Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T., Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S., Sanders M., Whitehead S., Quail M.A., Dougan G., Parkhill J., Prentice M.B.;
"The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081.";
PLoS Genet. 2:2039-2051(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AM286415; CAL12827.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001006984.1; -.
3D structure databases
ModBase A1JTY5.
Ontologies
GO
GO:0016619; Molecular function: malate dehydrogenase (oxaloacetate-decarboxylating) activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01619; -; 1.
PBIL [Tree]
InterPro IPR015884; Malic_enzyme_CS.
IPR012301; Malic_N.
IPR012302; Malic_NAD_bd.
IPR001891; Malic_OxRdtase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF00390; malic; 1.
PF03949; Malic_M; 1.
Pfam graphical view of domain structure.
PRINTS PR00072; MALOXRDTASE.
PROSITE PS00331; MALIC_ENZYMES; 1.
BLOCKS A1JTY5.
Genome annotation databases
GeneID 4712450; -.
GenomeReviews AM286415_GR; YE2794.
KEGG yen:YE2794; -.
NMPDR fig|630.2.peg.2722; -.
CMR A1JTY5; YE2794.
Other
ProtoNet A1JTY5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Metal-binding; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   565  565     NAD-dependent malic enzyme. PRO_1000069552
ACT_SITE   104   104        Proton donor (By similarity). 
ACT_SITE   175   175        Proton acceptor (By similarity). 
METAL   246   246        Divalent metal cation (By similarity). 
METAL   247   247        Divalent metal cation (By similarity). 
METAL   270   270        Divalent metal cation (By similarity). 
BINDING   157   157        NAD (By similarity). 
BINDING   270   270        NAD (By similarity). 
BINDING   418   418        NAD (By similarity). 
SITE   270   270  1     Important for activity (By similarity). 
Sequence information
Length: 565 AA [This is the length of the unprocessed precursor] Molecular weight: 62672 Da [This is the MW of the unprocessed precursor] CRC64: 433B11E44E441B40 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MELEYESKRP LYIPYAGPIL LEFPLLNKGS AFTNDERSHF NLHGLLPEAV ETIEEQAERA 

        70         80         90        100        110        120 
YRQYQDFKND DDKHIYLRNI QDTNETLFYR LLEAHLSEMM PIIYTPTVGE ACEHFSDIYR 

       130        140        150        160        170        180 
RARGLFISYP NREHIDDMLQ NATKQNVKVI VVTDGERILG LGDQGIGGMG IPIGKLSLYT 

       190        200        210        220        230        240 
ACGGISPAYT LPVVLDVGTN NPQRLNDPLY MGWRHPRISG DEYYAFVDEF IQAVKRRWPN 

       250        260        270        280        290        300 
VLLQFEDFAQ NNATPLLNRY RDELCCFNDD IQGTAAVTLG SLIAASHAAG SQLRDQTVTF 

       310        320        330        340        350        360 
LGAGSAGCGI AEQIIAQMIS EGLSEEQARA RVFMVDRFGL LTDKLPNLLD FQSKLVQKSD 

       370        380        390        400        410        420 
ALQSWNLTSD SISLQDVVRN AKPTVLIGVS GQPGLFTEEL IREMHKHCAR PIVMPLSNPT 

       430        440        450        460        470        480 
SRVEARPEDI INWTDGAALV ATGSPFSPVS YKEKLYPIAQ CNNSYIFPGI GLGVLASGAK 

       490        500        510        520        530        540 
RVTDGMLMAA SRALAQCSPL AQNGEGALLP NIDDIQAVSK TIAMQVGKAA QLQGVAIVTS 

       550        560 
EEALAKAIEH NYWQPQYRTY KRTSF
A1JTY5 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ch flag SIB Switzerland Mirror sites: Australia Brazil Canada China Korea
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!