[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Suzuki T., Tsuda Y., Kanou N., Inoue T., Kumazaki K., Nagano S., Hirai S., Tanaka K., Watanabe K.; "Bifidobacterium adolescentis complete genome sequence."; Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate.
PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from HCO(3)(-): step 2/6 .
SIMILARITY: Belongs to the ATCase/OTCase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AP009256; BAF39540.1; ALT_INIT; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_909622.1; -.

3D structure databases

ModBase

A1A1F7.

Ontologies

GO:0004070;	Molecular function: aspartate carbamoyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0006221;	Biological process: pyrimidine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00001; -; 1.
PBIL [Tree]

InterPro

IPR006130; Asp/Orn_carbamoyltranf.
IPR006132; Asp/Orn_carbamoyltranf_P_bd.
IPR006131; Asp_carbamoyltransf_Asp/Orn_bd.
IPR002082; Aspartate_carbamoyltransf_euk.
Graphical view of domain structure.

Pfam

PF00185; OTCace; 1.
PF02729; OTCace_N; 1.
Pfam graphical view of domain structure.

PRINTS

PR00100; AOTCASE.
PR00101; ATCASE.

TIGRFAMs

TIGR00670; asp_carb_tr; 1.

PROSITE

PS00097; CARBAMOYLTRANSFERASE; 1.

BLOCKS

A1A1F7.

Genome annotation databases

GeneID

4556605; -.

GenomeReviews

AP009256_GR; BAD_0759.

KEGG

bad:BAD_0759; -.

NMPDR

fig|1680.3.peg.1341; -.

CMR

A1A1F7; BAD_0759.

Other

ProtoNet

A1A1F7.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Pyrimidine biosynthesis; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 320`	`320`		`Aspartate carbamoyltransferase.`	`PRO_0000321075`

Sequence information

Length: 320 AA [This is the length of the unprocessed precursor]

Molecular weight: 35386 Da [This is the MW of the unprocessed precursor]

CRC64: F8A289FC738699AD [This is a checksum on the sequence]

        10         20         30         40         50         60 
MVGKSVITLD DLSIRQIQEM LHKAQYIDSH RKEVAHTCEG RVLATLFYEP STRTRLSFET 

        70         80         90        100        110        120 
AMLRLGGKVI GFAGAQLASV TKGETIADTL KTVSNYVDVV AIRHPKEGAA LVASRAASVP 

       130        140        150        160        170        180 
VINAGDGGHM HPTQTLADLA TLQSRFGRVT NLTVGLCGDL TFGRTVHSLI ETLCRFGNVN 

       190        200        210        220        230        240 
FVLISPDELK TPQYVLDRIN ATESCSYTEV KDLVSVIGDL DVLYMTRVQK ERFFNEDDYL 

       250        260        270        280        290        300 
RLRDTYILDE AKMAYAKKDM AVLHPLPRVN EIAVEVDDDP RAAYFEQVKN GMLMRMALES 

       310        320 
SVVGDELPGY EPLAAKEVEA

A1A1F7 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools