SWISS-PROT RELEASE 4.0
Announcing SWISS-PROT release 4.0
Release 4.0 of the SWISS-PROT data bank is now available. The total
number of sequence entries has grown from 4160 (in release 3.0) to 4387
and the total number of amino-acids from 969,641 to 1,036,010.
Release 4.0 has been updated using protein sequence data from release
11.0 of the P.I.R(1) protein data bank, as well as translation of
nucleic-acid sequence data from release 10.0 of the EMBL nucleotide data
library.
The DR line.
This release introduce an new type of data line, the DR line which is
used as a pointer on the existence of information relative to the
stored sequence in data collections external to SWISS-PROT.
For example: if the X-ray crystallographic atomic coordinate of a
sequence are stored in the Brookhaven Protein Data Bank (PDB) there now
is a DR line(s) pointing to the entry(s) in that data bank which
correspond to that sequence. All the sequences adapted from the PIR data
bank have a DR line pointing to the original PIR entry.
The general format of the DR line is the following:
DR DATA_BANK_IDENTIFIER; PRIMARY_IDENTIFIER; SECONDARY_IDENTIFIER.
Examples of complete DR lines are shown here:
DR PIR; KIPGA; RELEASE 11.0, DECEMBER 1986.
DR PDB; 2ADK; 30-SEP-83.
DR EMBL; X01704; GMNOD23.
In addition a new keyword: 3D-STRUCTURE has been added to all the
sequence entries which have a DR line pointing on the PDB structural
data bank.
Availability of SWISS-PROT.
- SWISS-PROT will soon be available, on-line, on the BIONET resource
computer.
- EMBL is distributing tapes of SWISS-PROT.
- American customers of PC/GENE can acquire SWISS-PROT from
IntelliGenetics on floppy media.
- European customers of PC/GENE will receive SWISS-PROT release 4.0
from GENOFIT.
The next release.
SWISS-PROT release 5.0 will be probably ready in the end of july or
beginning of august 1987, it will include new data from P.I.R release
12, a high number of translated EMBL sequences (more then 300 from
release 10.0 and 11.0) and sequences entered by the staff of Medical
Biochemistry Department of the University of Geneva. A great proportion
of all the sequences which are stored in SWISS-PROT and which were
sequenced at the DNA or RNA level will have DR lines pointing to the
primary accession number of the nucleotide sequence entry in EMBL.
Direct submission of data.
We accept and encourage direct submission of data to the SWISS-PROT data
bank. You can either send your sequence(s) on a number of different
computer media (tape, 360 Kb or 1.2Mb IBM PC floppy disks, 720 Kb 3'5
inch disks, most CP/M disk formats, SoftStrip) to our address in
Switzerland or send your sequence(s) by electronic mail to the following
adresses:
On BIONET: bairoch(@BIONET-20.ARPA)
On BITNET: bairoch@cgecmu51.bitnet
A. Bairoch / 10 June 1987.
Medical Biochemistry Department.
University of Geneva.
1, Rue Michel Servet
1211 Geneva 4
Switzerland.
____________________
(1) P.I.R (Protein Identification Resource) is supported by the
Division of Research Resources of the NIH and prepared by the staff
of the National Biomedical Research Foundation.
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