Species code:	YERPN
Taxonomy:	Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Yersinia (TaxID: 377628) [NEWT/ NCBI]
Description:	Gram-negative straight rods, sometimes approaching a spherical shape. Y.pestis is always nonmotile. It is the causative agent of plague which is primarily a disease of wild rodents. Y.pestis is transmitted among wild rodents by fleas, in which the bacteria multiply and block the esophagus and the pharynx. The fleas regurgitate the bacteria when they take their next blood meal. Bacteria are transmitted subcutaneously to humans by the bite of infected fleas, but also by air, especially during pandemics of disease. Infective flea bites produce the typical bubonic form of plague in humans. Y.pestis is very closely related to the gastrointestinal pathogen Yersinia pseudotuberculosis, and it has been proposed that Y.pestis evolved from Y.pseudotuberculosis 1,500-20,000 years ago.
Properties:	Presence of flagella: No Interaction: Animal pathogen in Mammalia Number of membranes: 2 Number of inteins:0
Statistics:	Number of YERPN entries in the UniProt Knowledgebase: 3946 (699 in UniProtKB/Swiss-Prot + 3247 in UniProtKB/TrEMBL)

Genome structure:	• Chromosome EMBL accession number CP000305 (circular; 4,534,590 bp) (download entry) (download Genome Reviews). • Plasmid pMT EMBL accession number CP000306 (circular; 100,918 bp) (download entry) (download Genome Reviews). • Plasmid pPCP EMBL accession number CP000307 (circular; 10,778 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] PubMed=16740952; [ NCBI , EBI , Israel , Japan ] Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M., Worsham P., Chu M.C., Andersen G.L. ; "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516: evidence of gene reduction in an emerging pathogen."; J. Bacteriol. 188:4453-4463(2006).
Web links:	Official genome site(s): http://genome.jgi-psf.org/finished_microbes/yespn/yespn.home.html Other web sites: Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid377628%5Borgn%5D ERIC: http://www.ericbrc.org/portal/eric/yersiniapestisbiovarantiquanepal516 GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Ypes_NEPAL516 PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p16646_Yer_pesti  EBI Proteome Analysis page

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