Species code:	SALTI
Taxonomy:	Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Salmonella (TaxID: 90370) [NEWT/ NCBI]
Description:	Gram-negative rod with peritrichous flagella. It is the aetiological agent of the typhoid fever, a serious disease of humans leading to 600'000 annual fatalities. Many S.enterica serovars actively invade the mucosal surface of the intestine but are normally contained in healthy individuals by the local immune defence mechanisms. However S.typhi has evolved the ability to spread to the deeper tissues of humans, including liver, spleen and bone marrow. Humans are the only known natural host of S.typhi, with S.typhi showing limited pathogenicity for most animals. S.typhi CT18 is an example of an emerging multiple drug resistant microorganism. Strain Ty2 has no plasmids.
Properties:	Presence of flagella: Yes Interaction: Animal pathogen in Mammalia Number of membranes: 2 Number of inteins:0
Statistics:	Number of SALTI entries in the UniProt Knowledgebase: 4718 (1324 in UniProtKB/Swiss-Prot + 3394 in UniProtKB/TrEMBL)

Genome structure:	• Chromosome EMBL accession number AL513382 (circular; 4,809,037 bp) (download entry) (download Genome Reviews). • Plasmid pHCM1 EMBL accession number AL513383 (circular; 218,160 bp) (download entry) (download Genome Reviews). • Plasmid pHCM2 EMBL accession number AL513384 (linear; 106,516 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] MEDLINE=21534947; PubMed=11677608; [ NCBI , EBI , Israel , Japan ] Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J., Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M., Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A., Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T., Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A., Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G. ; "Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18."; Nature 413:848-852(2001).
Web links:	Official genome site(s): http://www.sanger.ac.uk/Projects/S_typhi/ Other web sites: CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Salmonella&GLspecies=enterica&GLstrain=typhiCT18 Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?db=genomeprj&cmd=Retrieve&dopt=Overview&list_uids=236 ERIC: http://www.ericbrc.org/portal/eric/salmonellatyphict18 GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Sent_CT18 Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Salmonella_enterica.html PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p236_Sal_enter TIGR CMR: http://cmr.tigr.org/tigr-scripts/CMR/GenomePage.cgi?database=ntst03  EBI Proteome Analysis page

Genome structure:	Chromosome EMBL accession number AE014613 (circular; 4,791,961 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] MEDLINE=22531367; PubMed=12644504; [ NCBI , EBI , Israel , Japan ] Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R. ; "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18."; J. Bacteriol. 185:2330-2337(2003).
Web links:	Official genome site(s): http://www.genome.wisc.edu/sequencing/sty2.htm Other web sites: CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Salmonella&GLspecies=enterica&GLstrain=Ty2 Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=371 ERIC: http://www.ericbrc.org/portal/eric/salmonellatyphity2 GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Sent_TYPHI_TY2 PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p371_Sal_enter TIGR CMR: http://cmr.tigr.org/tigr-scripts/CMR/GenomePage.cgi?database=ntst04  EBI Proteome Analysis page

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