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HAMAP: Rickettsia typhi complete proteome

General information

Species:  Rickettsia typhi
Species code: RICTY
Taxonomy: Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; Rickettsiaceae; Rickettsieae; Rickettsia; typhus group (TaxID: 785) [NEWT/ NCBI]
Description: Rickettsia typhi is the causative agent of murine typhus or endemic typhus. Infection with Rickettsia typhi causes headache, fever, myalgia and leads to multisystem disease, including infection of the brain, lung, liver, kidney and heart. In severe cases R.typhi can cause meningoencephalitis, interstitial pneumonia and disseminated vascular lesions. It can be transmitted to the mammalian host by the bite of an infected flea or louse but the most important mechanism of inoculation is through the feces of the vector. Although distributed worldwide, it is mostly present in warm coastal areas harbouring large rat populations.
Properties: Presence of flagella: No
Interaction: Animal pathogen in Mammalia (intracellular obligate)
Number of membranes: 2
Number of inteins:0
Statistics: Number of RICTY entries in the UniProt Knowledgebase: 837 (406 in UniProtKB/Swiss-Prot + 431 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    ATCC VR-144 / Wilmington
Genome structure:
Chromosome EMBL accession number AE017197 (circular; 1,111,496 bp) (download entry) (download Genome Reviews).
Reference(s):
[1] PubMed=15317790; [ NCBI , EBI , Israel , Japan ]
McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A., Hong C., Yu X.-J., Walker D.H., Weinstock G.M. ;
"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae.";
J. Bacteriol. 186:5842-5855(2004).
Web links:
Official genome site(s):
http://www.hgsc.bcm.tmc.edu/projects/microbial/Rtyphi/
Other web sites:
CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Rickettsia&GLspecies=typhi&GLstrain=Wilmington
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid257363%5Borgn%5D
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Rtyp_WILMINGTON
Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Rickettsia_typhi.html
PATRIC: http://patric.vbi.vt.edu/genome/overview.php?genomeId=2633
PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p10679_Ric_typhi
TIGR CMR: http://cmr.tigr.org/tigr-scripts/CMR/GenomePage.cgi?database=ntrt01
 EBI Proteome Analysis page
 UniProtKB/Swiss-Prot document



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