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HAMAP: Rickettsia akari (strain Hartford) complete proteome

General information

Species:  Rickettsia akari (strain Hartford)
Species code: RICAH
Taxonomy: Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group (TaxID: 293614) [NEWT/ NCBI]
Description: Rickettsia akari is the causative agent of rickettsialpox. The disease was first described in 1946 in residents of the borough of Queens, in New York. Small outbreaks of rickettsialpox occured in several U.S cities, including Boston and Cleveland. About half of the cases occured in New York. To date, most cases have occurred in large metropolitan areas of the northeastern United State. Recently cases of rickettsialpox have been reported in Ukraine and Croatia. Rickettsia akari is transmitted among house mice and to humans by the house mouse mite Liponyssoides sanguineus but isolations have also been made from Korean voles in an area where rickettsialpox has not been reported. The first symptom of rickettsialpox is a papule which appears at the site of the original bite. The papule develops a tiny, fluid-filled vesicle. The vesicle sloughs away, leaving a crusty black scab (eschar) in its place. In about a week, the patient develops a fever, chills, heavy sweating, headache, eye pain (especially when exposed to light), weakness, and achy muscles. The fever rises and falls over the course of about a weak. A bumpy rash spreads across the body.
Properties: Presence of flagella: No
Interaction: Animal pathogen in Mammalia (intracellular obligate)
Number of membranes: 2
Number of inteins:0
Statistics: Number of RICAH entries in the UniProt Knowledgebase: 1257 (234 in UniProtKB/Swiss-Prot + 1023 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    Hartford
Genome structure:
Chromosome EMBL accession number CP000847 (linear; 1,231,060 bp) (download entry) (download Genome Reviews).
Reference(s):
[1] Madan A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Dasch G., Eremeeva M. ;
"Complete genome sequence of Rickettsia akari.";
Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
Web links:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=12953
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Raka_Hartford
PATRIC: http://patric.vbi.vt.edu/genome/overview.php?genomeId=269
 EBI Proteome Analysis page



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