Species code:	PSEE4
Taxonomy:	Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas (TaxID: 384676) [NEWT/ NCBI]
Description:	P. entomophila is a bacterial strain isolated from a fruit fly from Guadeloupe. Upon ingestion it kills Drosophila melanogaster larvae and adults, as well as insects from other orders. Its persistence in the insect gut triggers a local and systemic immune response in the insect, making it a useful model for insect pathogenesis; indeed it is the first natural pathogen of D.melanogaster known. P. entomophila is unusual in that it does not have a type III or type IV secretion system, one of which is usually found in pathogens. The mode by which it kills is not clear, although the genome encodes several insecticidal toxins, a diffusible haemolytic activity, several lipases, a number of extracellular proteases and potential adhesions which cluster with type I or II secretion system proteins. It may also be able to produce hydrogen cyanide and novel secondary metabolites which could contribute to its lethality.
Properties:	Presence of flagella: Yes Interaction: Animal pathogen in Insecta Number of membranes: 2 Number of inteins:0
Statistics:	Number of PSEE4 entries in the UniProt Knowledgebase: 5126 (488 in UniProtKB/Swiss-Prot + 4638 in UniProtKB/TrEMBL)

Genome structure:	Chromosome EMBL accession number CT573326 (circular; 5,888,780 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] PubMed=16699499; [ NCBI , EBI , Israel , Japan ] Vodovar N., Vallenet D., Cruveiller S., Rouy Z., Barbe V., Acosta C., Cattolico L., Jubin C., Lajus A., Segurens B., Vacherie B., Wincker P., Weissenbach J., Lemaitre B., Medigue C., Boccard F. ; "Complete genome sequence of the entomopathogenic and metabolically versatile soil bacterium Pseudomonas entomophila."; Nat. Biotechnol. 24:673-679(2006).
Web links:	Official genome site(s): http://www.genoscope.cns.fr/spip/Pseudomonas-a-model-pathogen-for.html Other web sites: Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid384676%5Borgn%5D GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Pent_L48 PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p16800_Pse_entom  EBI Proteome Analysis page

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