Species code:	NOVAD
Taxonomy:	Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales; Sphingomonadaceae; Novosphingobium (TaxID: 279238) [NEWT/ NCBI]
Description:	Novosphingobium (Sphingomonas) aromaticivorans strain DSM 12444 is an alpha Proteobacterium and is characterized as a Gram-negative, non-spore forming rod displaying a single polar flagellum when it is motile. It is yellow pigmented and obligately aerobic. Unlike typical gram-negative bacteria, it does not have lipopolysaccharide, but rather glycosphingolipid, which is usually a membrane component of eukaryotic cells. The thermoreversible gel formation and solution viscosity properties of these glycosphingolipids (sphingans) make them of technical interest and useful in applications for a wide range of food and pharmaceutical products. The role of sphingans has been proposed to be important in colonization of eukaryotic organisms including plants, marine organisms, and humans by Novosphingobium. N. aromaticivorans strains have been isolated from a wide variety of sources including soil, both marine and fresh waters, marine life, and from plants. Many of the first isolates assigned to this genus (S. paucimobilis) were derived from human clinical specimens or water samples taken from hospital environments and members of this species have been subsequently shown to behave as opportunistic pathogens. More recently, N. aromaticivorans has been linked to the death of coral reefs off the Florida coast. Although there is an emerging role of Novosphingobium species in disease, members of this genus are best known for their ability to degrade a wide variety of aromatic hydrocarbons.
Properties:	Presence of flagella: No Interaction: No Number of membranes: 2 Number of inteins:0
Statistics:	Number of NOVAD entries in the UniProt Knowledgebase: 3917 (277 in UniProtKB/Swiss-Prot + 3640 in UniProtKB/TrEMBL)

Genome structure:	• Chromosome EMBL accession number CP000248 (circular; 3,561,584 bp) (download entry) (download Genome Reviews). • Plasmid pNL2 EMBL accession number CP000677 (circular; 487,268 bp) (download entry) (download Genome Reviews). • Plasmid pNL1 EMBL accession number CP000676 (circular; 184,462 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Fredrickson J., Balkwill D., Romine M.F., Richardson P. ; "Complete sequence of Novosphingobium aromaticivorans DSM 12444."; Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases. [2] Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Han C., Thomson S., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Fredrickson J., Romine M.F., Richardson P. ; "Complete sequence of plasmid pNL2 of Novosphingobium aromaticivorans DSM 12444."; Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases. [3] Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Han C., Thomson S., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Fredrickson J., Romine M.F., Richardson P. ; "Complete sequence of plasmid pNL1 of Novosphingobium aromaticivorans DSM 12444."; Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
Web links:	Official genome site(s): http://genome.jgi-psf.org/finished_microbes/novar/novar.home.html Other web sites: CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Novosphingobium&GLspecies=aromaticivorans&GLstrain=DSM12444 Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid279238%5Borgn%5D GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Naro_DSM12444 PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p204_Nov_aroma  EBI Proteome Analysis page

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