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HAMAP: Helicobacter pylori (strain B38) complete proteome

General information

Species:  Helicobacter pylori (strain B38)
Species code: HELPB
Taxonomy: Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Helicobacteraceae; Helicobacter (TaxID: 592205) [NEWT/ NCBI]
Description: Micro-aerophilic, Gram-negative, slow-growing, spiral-shaped and flagellated organism. H.pylori is probably the most common cause of chronic bacterial infection of humans, present in almost half of the world population. The presence of the bacterium in the gastric mucosa is associated with chronic active gastritis and is implicated in more severe gastric diseases, including chronic atrophic gastritis, peptic ulceration and mucosa-associated lymphoid tissue lymphomas.
B38 was isolated from a gastric mucosa-associated lymphoid tissue; thus it is referred to as a MALT strain. The strain is mildly inflammatory.
Properties: Presence of flagella: Yes
Human pathogen: Yes
Interaction: Animal pathogen in Mammalia
Number of membranes: 2
Number of inteins:0
Statistics: Number of HELPB entries in the UniProt Knowledgebase: 1369 (2 in UniProtKB/Swiss-Prot + 1367 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    B38
Genome structure:
Chromosome EMBL accession number FM991728 (circular; 1,576,758 bp) (download entry) (download Genome Reviews).
Reference(s):
[1] Thiberge J.M., Boursaux-Eude C., Lehours L., Dillies D., Creno C., Coppee C., Rouy R., Lajus L., Ma M., Burucoa C., Vincent P., Ruskone-Foumestraux A., Courillon-Mallet A., Lamarque D., Megraud F., Medigue C., Bouchier C., Delchier C., Labigne A., Raymond J. ;
"From array-based hybridization of Helicobacter pylori isolates to complete genome sequence of an isolate associated with MALT lymphoma.";
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
Web links:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=39685
Genome Atlas: http://www.cbs.dtu.dk/services/gwBrowser/precalc/project.php?pid=39685
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Hpyl_B38
Unofficial: http://www.pasteur.fr/recherche/RAR/RAR2007/Upbm-en.html
 EBI Proteome Analysis page



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