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HAMAP: Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT) complete proteome

General information

Species:  Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT)
Species code: HAMD5
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; aphid secondary symbionts; Candidatus Hamiltonella (TaxID: 572265) [NEWT/ NCBI]
Description: Hamiltonella defensa, is a maternally transmitted, defensive secondary endosymbiont found sporadically in sap-feeding insects, including aphids, psyllids, and whiteflies. Its closest free-living relatives include Yersinia and Serratia species. It cannot live outside its host but is not essential for host survivial, unlike Buchnera, another aphid endosymbiont. In pea aphids (Acyrthosiphon pisum), H. defensa can block larval development of the solitary endoparasitoid wasps Aphidius ervi and Aphidius eadyi, rescuing the aphid host. Protection is correlated with the presence of a temperate, lambda-like bacteriophage APSE, which infects H. defensa. The bacteriphage encodes various toxins thought to be important in protection. H. defensa and APSE can also be transmitted horizontally; protection by H. defensa has been shown to be transferable between distantly related aphid species. H. defensa probably relies on Buchnera, the required aphid endosymbiont for most essential amino acids and a few cofactors, as does the aphid host (adapted from PubMed 19451630).
Properties: Presence of flagella: not known
Human pathogen: No
Interaction: Animal endosymbiont in Aphids (obligate endosymbiont)
Number of membranes: 1?
Number of inteins: 1
Statistics: Number of HAMD5 entries in the UniProt Knowledgebase: 2045 (224 in UniProtKB/Swiss-Prot + 1821 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    5AT
Genome structure:
• Chromosome EMBL accession number CP001277 (circular; 2,110,331 bp) (download entry) (download Genome Reviews).
• Plasmid pHD5AT EMBL accession number CP001278 (circular; 59,032 bp) (download entry) (download Genome Reviews).
Reference(s):
[1] PubMed=19451630; [ NCBI , EBI , Israel , Japan ]
Degnan P.H., Yu Y., Sisneros N., Wing R.A., Moran N.A. ;
"Hamiltonella defensa, genome evolution of protective bacterial endosymbiont from pathogenic ancestors.";
Proc. Natl. Acad. Sci. U.S.A. 106:9063-9068(2009).
Web links:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=31259
Genome Atlas: http://www.cbs.dtu.dk/services/gwBrowser/precalc/project.php?pid=31259
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Cham_defensa5AT
 EBI Proteome Analysis page



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