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HAMAP: Clostridium thermocellum (strain ATCC 27405 / DSM 1237) complete proteome

General information

Species:  Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
Species code: CLOTH
Taxonomy: Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium (TaxID: 203119) [NEWT/ NCBI]
Description: Clostridium thermocellum is a Gram-positive, anaerobic, thermophilic plant cell wall degrading bacterium capable of converting cellulosic substrates into ethanol. Degradation of cellulose occurs extracellularly in a large complex called the cellulosome. This nanomachine contains about 20 catalytic components, and can attach to the surface of the host organism. The complex is built on a "scaffoldin" subunit onto which the catalytic subunits are added through interactions of the "cohesion" domains of the enzymes with the "dockerin" domains on the scaffold. The C.thermocellum cellulosome is the best-characterized cellulase complex and thus serves as a paradigm. Continuing research on the cellulosome and its producer will provide crucial information for better understanding the cellulolytic reaction, a key process in biomass conversion (adapted from http://genome.jgi-psf.org/draft_microbes/cloth/cloth.home.html).
Properties: Presence of flagella: not known
Human pathogen: No
Interaction: Plant saprophyte
Number of membranes: 1
Number of inteins: 14 in 14 different sequences
Statistics: Number of CLOTH entries in the UniProt Knowledgebase: 3102 (291 in UniProtKB/Swiss-Prot + 2811 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    ATCC 27405 / DSM 1237
Genome structure:
Chromosome EMBL accession number CP000568 (circular; 3,843,301 bp) (download entry) (download Genome Reviews).
Reference(s):
[1] Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Wu J.H.D., Newcomb M., Richardson P. ;
"Complete sequence of Clostridium thermocellum ATCC 27405.";
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
Web links:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid203119%5Borgn%5D
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Cthe_ATCC27405
Pathema: http://pathema.jcvi.org/tigr-scripts/Clostridium/shared/GenomePage.cgi?org=ntcm01
 EBI Proteome Analysis page



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