Species code:	CHLFF
Taxonomy:	Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae; Chlamydophila (TaxID: 264202) [NEWT/ NCBI]
Description:	Chlamydophila felis is the causative agent of conjunctivitis in cats. Although conjunctivitis is the major clinical sign, there may also be mild sneezing and nasal discharge in some affected cats. Occasionally there is a mild fever which can result in lethargy and inappetence but, generally, affected cats remain bright and eat well. If left untreated, the conjunctivitis often persists for six to eight weeks or longer and cats may continue to shed the organism for many months. Chlamydophila felis also causes pneumonitis and has been found in the gastrointestinal tract and reproductive tract of cats and there is some speculation that it may be a cause of infertility in breeding queens. Chlamydophila infection is relatively common in cats and up to 30% of cases of chronic conjunctivitis may be caused by this organism. The bacterium requires direct contact between cats to spread. Although cats of all ages can be infected, disease is seen most commonly in young kittens (5 - 12 weeks old) with persistent or recurrent infection. Seroepidemiologic studies have shown that the bacterium is present in 1.7% of the general human population and 8.8% of veterinarians in small animal clinics in Japan. The infection in human is most likely acquired from infected cats but rarely causes any serious illness in humans. The genome of C.felis is made up of one circular chromosome and one plasmid pCfe1.
Properties:	Presence of flagella: No Interaction: Animal pathogen in Mammalia Number of membranes: 2 Number of inteins:0
Statistics:	Number of CHLFF entries in the UniProt Knowledgebase: 1013 (217 in UniProtKB/Swiss-Prot + 796 in UniProtKB/TrEMBL)

Genome structure:	• Chromosome EMBL accession number AP006861 (circular; 1,166,239 bp) (download entry) (download Genome Reviews). • Plasmid pCfe1 EMBL accession number AP006862 (circular; 7,552 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] PubMed=16766509; [ NCBI , EBI , Israel , Japan ] Azuma Y., Hirakawa H., Yamashita A., Cai Y., Rahman M.A., Suzuki H., Mitaku S., Toh H., Goto S., Murakami T., Sugi K., Hayashi H., Fukushi H., Hattori M., Kuhara S., Shirai M. ; "Genome sequence of the cat pathogen, Chlamydophila felis."; DNA Res. 13:15-23(2006).
Web links:	Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid264202%5Borgn%5D GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Cfel_FEC56 NMPDR: http://www.nmpdr.org/FIG/wiki/rest.cgi/NmpdrPlugin/SeedViewer?pattern=264202.3;page=SearchResult PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p370_Chl_felis  EBI Proteome Analysis page

• Genome Proximity Viewer: This program displays the genes that are found in the genomic environment of a selected locus.
  
  
• Perform a BLAST search against all proteins from this proteome
  
  
• Download a file by FTP containing all UniProt Knowledgebase entries of this proteome
  • in UniProt Knowledgebase format
  • in FASTA format
  
  
• Retrieve set of characterized or identified proteins for this proteome
  
  
• Retrieve set of proteins with 3D structure for this proteome