Species code:	ANAPZ
Taxonomy:	Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; Anaplasmataceae; Anaplasma; phagocytophilum group (TaxID: 212042) [NEWT/ NCBI]
Description:	Anaplasma phagocytophilum (strain HZ) is an intracellular vector-borne pathogen that causes human ehrlichiosis. It depends on hematophagous ticks as a vector and wild mammals as a reservoir host. It is transmitted by Ixodes spp. A.phagocytophilum is the causative agent of human granulocytic anaplasmosis (HGA), formerly recognized as human granulocytic ehrlichiosis (HGE). HGA is indistinguishable from human monocytic ehrlichiosis (HME), caused by Ehrlichia chaffeensis. Prior to 1994, only ruminant and equine ehrlichiosis were known to be caused by A.phagocytophilum. This organism is one of the leading causes of ehrlichiosis in the world.
Properties:	Presence of flagella: No Interaction: Animal pathogen in Mammalia Number of membranes: 2 Number of inteins:0
Statistics:	Number of ANAPZ entries in the UniProt Knowledgebase: 1244 (142 in UniProtKB/Swiss-Prot + 1102 in UniProtKB/TrEMBL)

Genome structure:	Chromosome EMBL accession number CP000235 (circular; 1,471,282 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] PubMed=16482227; [ NCBI , EBI , Israel , Japan ] Dunning Hotopp J.C., Lin M., Madupu R., Crabtree J., Angiuoli S.V., Eisen J.A., Seshadri R., Ren Q., Wu M., Utterback T.R., Smith S., Lewis M., Khouri H., Zhang C., Niu H., Lin Q., Ohashi N., Zhi N., Nelson W.C., Brinkac L.M., Dodson R.J., Rosovitz M.J., Sundaram J.P., Daugherty S.C., Davidsen T., Durkin A.S., Gwinn M.L., Haft D.H., Selengut J.D., Sullivan S.A., Zafar N., Zhou L., Benahmed F., Forberger H., Halpin R., Mulligan S., Robinson J., White O., Rikihisa Y., Tettelin H. ; "Comparative genomics of emerging human ehrlichiosis agents."; PLoS Genet. 2:208-222(2006).
Web links:	CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Anaplasma&GLspecies=phagocytophilum&GLsupStrain=HZ Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid212042%5Borgn%5D GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Apha_HZ PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p336_Ana_phago  EBI Proteome Analysis page

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