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External resources - (No support from the ExPASy Team)Showing 10 records out of 10 total
DAS (Dense Alignment Surface) is based on low-stringency dot-plots of the query sequence against a set of library sequences - non-homologous membrane proteins - using a previously derived, special scoring matrix. The method provides a high precision hyrdophobicity profile for the query from which the location of the potential transmembrane segments can be obtained. The novelty of the DAS-TMfilter algorithm is a second prediction cycle to predict TM segments in the sequences of the TM-library.
Prediction of transmembranes helices and topology of proteins.
predicting coiled-coils in protein sequences
Prediction of transmembrane topology and signal peptides from the amino acid sequence of a protein.
PredictProtein integrates feature prediction for secondary structure, solvent accessibility, transmembrane helices, globular regions, coiled-coil regions, structural switch regions, B-values, disorder regions, intra-residue contacts, protein-protein and protein-DNA binding sites, sub-cellular localization, domain boundaries, beta-barrels, cysteine bonds, metal binding sites and disulphide bridges.
Classification and Secondary Structure Prediction of Membrane Proteins.
TMHMM is a membrane protein topology prediction method based on a hidden Markov model (HMM). It predicts transmembrane helices in proteins.
The TMpred program makes a prediction of membrane-spanning regions and their orientation. The algorithm is based on the statistical analysis of TMbase, a database of naturally occurring transmembrane proteins
UniProtKB/Swiss-Prot is the manually annotated component of UniProtKB. It contains manually-annotated (reviewed) records with information extracted from the literature and curator-evaluated computational analysis.
keywords: disease mutation, enzyme (catalytic activity), family database, functional annotation, gene nomenclature, glycosylation, influenza, pathway, physico-chemical property, post-translational modification (PTM), protein data bank (PDB), protein domain, protein family, protein function, protein nomenclature, protein sequence analysis (primary structure), protein variation (variant), quaternary structure, secondary structure, sequence alignment, sequence analysis, tertiary structure, topology prediction, transmembrane (trans-membrane)