Categories: genomics, (characterisation/annotation) -
Software type(s): website, CLI -
tool
The ChIP-Seq tools are used to analyze ChIP-seq data and other types of mass genome annotation data (MGA).The programs are: a feature correlation tool (ChIP-cor); a tag centering tool (ChIP-center); a signal peak detection tool (ChIP-peak and a partitioning tool (ChIP-part)
Categories: proteomics, (post-translational modification), genomics, (characterisation/annotation), systems biology, transcriptomics -
Software type(s): website, GUI -
tool
MARA models genome-wide expression data in terms of our genome-wide annotations of regulatory sites. For a given expression data-set it infers the key transcription regulators, their sample-dependent activities, and their genome-wide targets.
keywords:
Bayesian network,
ChIP-seq,
hidden markov model (HMM),
maximum likelihood,
network,
next generation sequencing (NGS),
promoter,
sequence analysis,
transcription factor binding site,
transcription module,
transcription regulation,
transcription start site annotation
Categories: genomics, (sequence alignment, similarity search), systems biology -
Software type(s): website, CLI, GUI -
tool
Phylogibbs is an algorithm for discovering regulatory sites in a collection of DNA sequences, including multiple alignments of orthologous sequences from related organisms.The algorithm uses a Gibbs sampling strategy, takes the phylogenetic relationships of the input sequences rigorously into account, and assigns realistic posterior probabilities to reported sites using a novel annealing+tracking strategy.
keywords:
alignment analysis,
Bayesian network,
ChIP-seq,
hidden markov model (HMM),
maximum likelihood,
model of evolution,
network,
next generation sequencing (NGS),
sequence alignment,
sequence analysis,
short sequence alignment,
transcription factor binding site,
transcription module,
transcription regulation
Categories: genomics, (characterisation/annotation) -
Software type(s): CLI -
tool
Software to analyse deep-sequencing (NGS) data and reconstruct haplotypes in a genetically heterogeneous sample
Categories: genomics, (characterisation/annotation), systems biology, transcriptomics -
Software type(s): website -
database
SwissRegulon is a database of genome-wide annotations of regulatory sites. It contains annotations for 17 prokaryotes and 3 eukaryotes. The database frontend offers an intuitive interface showing genomic information in a clear and comprehensible graphical form.
keywords:
ChIP-seq,
network,
next generation sequencing (NGS),
promoter,
sequence alignment,
sequence analysis,
short sequence alignment,
transcription factor binding site,
transcription module,
transcription regulation,
transcription start site annotation