Home
About
What's new?
Contact
Support
SIB Groups
Find resources
Query all databases
- Query within a category:
genomics
phylogeny/evolution
proteomics
- Query a specific database:
ENZYME
GPSDB
HAMAP
miROrtho
MyHits
OMA
OpenFlu
OrthoDB
PROSITE
Protein Spotlight
Selectome
STRING
SWISS-2DPAGE
SWISS-MODEL Repository
SwissDock
SwissVar
UniProtKB
ViralZone
World-2DPAGE Repository
search
help
Visual Guidance
DNA
RNA
Protein
Cell
Organism
Population
Categories
proteomics
protein sequences and identification
mass spectrometry and 2-DE data
protein characterisation and function
families, patterns and profiles
post-translational modification
protein structure
protein-protein interaction
similarity search/alignment
genomics
sequence alignment
similarity search
characterisation/annotation
structural bioinformatics
systems biology
phylogeny/evolution
population genetics
transcriptomics
biophysics
imaging
IT infrastructure
drug design
Resources A..Z
Links/Documentation
Search for Resources
Advanced Search
Hide
Category
all
proteomics
genomics
structural bioinformatics
systems biology
phylogeny/evolution
population genetics
transcriptomics
biophysics
imaging
IT infrastructure
drug design
Keywords
Software Type
all
API
CLI
GUI
databases files
library
website
S I B Group
any
Bioinformatics Core Facility (M. Delorenzi)
Bioinformatics Systems Biology (C. von Mering)
CALIPHO (A. Bairoch - L. Lane)
Computational Biochemistry Research (G. Gonnet)
Computational Biology (N. Beerenwinkel)
Computational Biology (S. Bergmann)
Computational Cancer Genomics (P. Bucher)
Computational Evolutionary Genomics (E. Zdobnov)
Computational Phylogenetics (N. Salamin)
Computational Structural Biology (T. Schwede)
Computational Systems Biology (J. Stelling)
Computational and Molecular Population Genetics (L. Excoffier)
Evolutionary Systems Biology (A. Wagner)
Evolutionary bioinformatics (M. Robinson-Rechavi)
Genome Systems Biology (E. van Nimwegen)
Molecular Modelling (O. Michielin)
Proteome Informatics (F. Lisacek)
RNA Regulatory Network (M. Zavolan)
Swiss-Prot (I. Xenarios - L. Bougueleret)
Vital-IT (I. Xenarios)
Alphabetical Index
SIB resources
External resources -
(No support from the ExPASy Team)
a
AACompIdent
• protein identification by aa composition
AACompSim
• amino acid composition comparison
Agadir
• Prediction of the helical content of peptides
ALF
• simulation of genome evolution
Alignment tools
• Four tools for multiple alignments
AllAll
• protein sequences comparisons
Anolea
• Atomic Non-Local Environment Assessment
APSSP
• Advanced Protein Secondary Structure Prediction
Arlequin
• software for population genetics
Ascalaph
• Molecular modeling software
Association Viewer
• SNPs display in a genetic context
b
BayeScan
• identify natural selection
Bgee
• gene expression patterns comparison
big-PI
• predict GPI modification sites
Biochemical Pathways
• Biochemical Pathways
BIONJ
• Neighbor Joining (NJ) phylogenetic analysis
BLAST
• sequence similarity search
BLAST (UniProt)
• BLAST search on the UniProt web site
BLAST - NCBI
• Biological sequence similarity search
BLAST - PBIL
• BLAST search on protein sequence databases
Blast2Fasta
• Blast to Fasta conversion
BLASTO
• BLAST on orthologous groups
boxshade
• MSA pretty printer
c
CFSSP
• Protein secondary structure prediction
ChIP-Seq
• ChIP-Seq data analysis tools
ChloroP
• chloroplast transit peptides & cleavage sites
Click2Drug
• Directory of computational drug design tools
CLIPZ
• binding sites of RNA-binding proteins
ClustalO (UniProt)
• Align two or more protein sequences
ClustalW
• Multiple sequence alignment
ClustalW - PBIL
• Multiple sequence alignment program
ClustalW2
• Multiple sequence alignment program
Codon Suite
• codon-based sequence analysis
Coiled-Coils prediction
• Prediction of coiled coils regions
COILS
• Prediction of Coiled Coil Regions in Proteins
ColorSeq
• Color Protein Sequence
Compute pI/MW
• theoretical pI and Mw computation
CPHmodels
• Protein homology modeling
CSS-Palm
• Prediction of palmitoylation sites in proteins
CT-CBN
• estimate conjunctive Bayesian networks
d
DAS-TMfilter
• Prediction of transmembrane regions
Decrease redundancy
• Sequence redundancy reduction
DendroUPGMA
• Dendrogram creation using the UPGMA algorithm
DIALIGN
• Local multiple sequence aligment
DictyOGlyc
• GlcNAc O-glycosylation sites in D.discoideum
DisEMBL
• Prediction of disordered protein regions
DLP-SVM
• Domain linker predictor
Dotlet
• sequence similarity plots
e
EasyProt
• graphical platform for proteomics analysis
efmtool
• elementary flux modes of metabolic networks
ELM
• Eukaryotic Linear Motifs
ElMMo
• miRNA target predictions
EMBnet services
• bioinformatics tools, databases and courses
EMBOSS translation tools
• sequence translation tools
ENZYME
• enzyme nomenclature
EPD
• collection of eukaryotic promoters
epestfind
• Identification of PEST motifs
ESTscan
• coding region detection
ESyPred3D
• Protein homology modeling
Evolutionary Trace Server (TraceSuite II)
• Maps evolutionary traces to structures
ExpressionView
• explore biclusters in gene expression data
f
FASTA/SSEARCH/GGSEARCH/GLSEARCH
• Sequence similarity searching of protein db
FastEpistasis
• test for epistasis effects
fastsimcoal
• coalescent simulation of genomic data
FetchGWI / tagger
• short sequence mapping
FindMod
• protein post-translational modification prediction
FindPept
• peptide identification from unspecific cleavage
FingerPRINTScan
• scan sequences against PRINTS
FUGUE
• Sequence-structure homology recognition
g
GENIO/logo
• RNA/DNA & Amino Acid Sequence Logos
Geno3D
• Protein molecular modelling
Genome History
• duplicate genes from complete genomes
GlobPlot
• Protein disorder/globularity/domain predictor
GlycanMass
• oligosaccharide structure mass calculation
GlycoMod
• oligosaccharide structure prediction
GlycoSuiteDB
• glycan database
Glycoviewer
• visualize a set of glycan structures
GMM
• copy number variation detection
GOR
• Protein secondary structure prediction
GPI-SOM
• identify GPI-anchor signals
GPS
• Prediction of kinase-specific phosphorylation site
GPSDB
• gene and protein synonyms
Graphical Codon Usage Analyser
• Codon bias
h
HAMAP
• UniProtKB family classification and annotation
HamapScan
• Scan protein sequences against the HAMAP families
HCA (hydrophobic cluster analysis)
• hydrophobic cluster analysis
HCD/CID spectra merger
• combine HCD and CID MS/MS spectra
HeliQuest
• alpha-helical properties screening
HHpred
• Homology detection & structure prediction
HMMTOP
• Prediction of transmembranes helices and topology
HTMSRAP
• Helical TransMembrane Prediction
i
ImageMaster / Melanie
• software for 2-D PAGE analysis
ImmunoDB
• insect immune-related genes and gene families
InterProScan
• Family and domain datatabase search
ISA
• gene expression module discovery
IScan
• insertion sequence identification
ISMARA
• genome-wide expression data modeling
IsotopIdent
• theoretical isotopic distribution
j
Jmol
• 3D molecule visualization tool
Jpred
• Secondary Structure Prediction Server
k
Kalign - EBI
• Fast and accurate multiple sequence alignment
Kalign - SBC
• Fast and accurate multiple sequence alignment
l
LALIGN
• Pairwise alignment
Linear Classification
• simple linear classification
LipoP
• predict lipoproteins and signal peptides
LiveBench
• Continuous Benchmarking of Structure Prediction Se
m
MADAP
• clustering for genome annotation data
MAFFT - CBRC
• Multiple sequence aligment
MAFFT - EBI
• Multiple sequence aligment
Make2D-DB II
• package to build web-based proteomics database
MakeMultimer.py
• Reconstruction of multimeric molecules in crystals
MALDIPepQuant
• quantify MALDI peptides
MAMOT
• HMM models
MARCOIL
• coiled-coils prediction
MarvinSpace
• Visualization, modeling and interactive rendering
Mascot
• protein identification from mass spectrometry data
MassSearch
• sequence search by mass spectrometry weights
MaxAlign
• Gap removal from alignments
Medline Ranker
• Ranking the biomedical literature
MeDor
• Metaserver for protein disorder prediction
MetaNetX
• Metabolic Network Repository & Analysis
MIAPEGelDB
• MIAPE document edition
miROrtho
• catalogue of animal microRNA genes
MITOPROT
• predict mitochondrial targeting sequences
MLtree
• maximum likelihood optimization
MLTreeMap
• phylogenetics and functionalities of metagenomes
MolTalk
• Environment for structural bioinformatics
MovieMaker
• Generates movies of protein dynamics
MSight
• mass spectrometry imager
Multialin
• Multiple sequence alignment
Multicoil
• Prediction of two- and three-stranded coiled coils
MUSCLE
• Multiple alignment server
MyDomains
• Image Creator
MyHits
• protein domains database and tools
Myristoylator
• N-terminal myristoylation prediction
n
NetAcet
• predict N-terminal acetylation sites
NetCGlyc
• C-mannosylation sites in mammalian proteins
NetCorona
• Coronavirus 3C-like proteinase cleavage sites
NetGlycate
• glycation of epsilon amino groups of lysines
NetNES
• Prediction of leucine-rich nuclear export signals
NetNGlyc
• N-glycosylation sites in human proteins
NetOGlyc
• mammalian mucin type GalNAc O-glycosylation sites
NetPhos
• predict phosphorylation in eukaryotes
NetPhosK
• Prediction of kinase-specific phosphorylation site
NetPhosYeast
• predict protein phosphorylation sites in yeast
NetPicoRNA
• Prediction of picornaviral protease cleavage sites
NetSurfP
• Protein Surface Accessibility Prediction
NetTurnP
• Prediction of Beta-turn regions in proteins
Newick Utilities
• high-throughput phylogenetic tree processing
neXtProt
• human proteins
nfswatch
• monitoring NFS traffic
NMT
• Predict N-terminal N-myristoylation of proteins
NQ-Flipper
• Correction of unfavorable rotamers of Asn and Gln
o
OMA
• orthology inference among complete genomes.
OMSSA
• MS/MS identification tool
One to Three
• 1- to 3-letter amino acid converter
OpenFlu
• Influenza genetic and epidemiological data
OpenStructure
• molecular modelling and visualization
OrthoDB
• Hierarchical catalog of eukaryotic orthologs
p
Paircoil
• Prediction of coiled coils regions
Paircoil2
• Prediction of coiled coils regions
PANDITplus
• protein families and domains resources
PATS
• predict apicoplast targeted sequences
PattInProt
• scan sequences against patterns, mismatch allowed
PaxDb
• protein abundance database
PDBePISA
• Protein Interfaces, Surfaces and Assemblies
PepDraw
• Peptide primary structure drawing
PepFrag
• Identify proteins from a tandem mass spectrum
PepMapper
• Peptide mass fingerprinting tool
PepPepSearch
• sequence-based search of Swiss-Prot
Peptide Builder
• Builds simple peptides and proteins
PeptideCutter
• protein cleavage sites prediction
PeptideMass
• peptides from protein cleavage
PEPVAC
• Prediction of MHCI-restricted epitopes
Pfam HMM Search
• Pfam database search
pftools
• Generalized profiles build and search tools
Phobius
• predict transmembrane topology and signal peptides
PHYLIP
• Package of programs for phyologenetic analysis
Phylogenetic Tree
• phylogenetic tree construction and printing
Phylogeny programs
• Links to phylogeny programs
Phylogeny.fr
• Simple phylogenetic analysis
Phylogibbs
• regulatory sites discovery
Phyre2
• 3D structure prediction with HMM
pIcarver
• theoretical distributions of peptide pI
Ping pong algorithm
• coherent patterns across paired datasets
PLOGO
• Sequence logos
Poodle
• Prediction of disordered protein regions
PoPMuSiC
• Thermodynamic stability prediction upon mutations
PORTER
• Protein Secondary Structure Prediction
PPSearch
• search a sequence against PROSITE patterns
PRATT
• find patterns in unaligned protein sequences
PRATT (EBI)
• find conserved patterns in unaligned sequences
PredictProtein
• Prediction of physico-chemical protein properties
Predotar
• predict putative N-terminal targeting sequences
PrePS
• predict protein prenylation
pROC
• visualize, smooth and compare ROC curves
PROCHECK
• Stereochemical quality of a protein structure
ProDom
• Scan a sequence against ProDom domain families
PROF
• Secondary Structure Prediction System
ProFound
• Search protein databases with peptide mass maps
Prolune
• Popular science articles (in French)
ProP
• Prediction of Arg & Lys propeptide cleavage sites
PROPSEARCH
• Functional and / or structural homolog search
ProSA-web
• Program of error recognition in 3D structures
PROSITE
• protein domains and families
ProtBud
• Comparison of asymmetric units and biological unit
Protein Colourer
• Tool for colouring amino acid sequences
Protein Disorder Predictors
• Protein Disorder Predictors
Protein Model Portal
• structural information for a protein
Protein Sequence Logos
• Protein sequence logo method
Protein Spotlight
• Informally written reviews on proteins
ProteinProspector
• Mass spectrometry database search tools
ProtParam
• protein physical and chemical parameters
ProtScale
• protein profile computation and representation
PSIPRED
• Various protein structure prediction methods
PSORT
• Protein subcellular location prediction
PTS1
• peroxisomal targeting signal 1 containing proteins
PVS - Protein Variability Server
• Protein sequence variability in MSA
PyMOL
• Molecular graphics visualization
q
QMEAN
• estimate quality of protein models
QuickMod
• identification of ms/ms data
r
Radar
• De novo repeat detection in protein sequences
RandSeq
• random protein sequence generator
Rankpep
• Prediction of MHC type I and II peptide binding
RasMol
• Molecular graphics visualization
RAxML
• ML inference of large phylogenetic trees
REP
• Protein search for repeats
REPRO
• De novo repeat detection in protein sequences
Reverse Transcription and Translation Tool
• Transcription, translation, reverse transcription
Reverse Translate
• Reverse translation
s
SAM-T08
• HMM-based Protein Structure Prediction
SAMBA
• Systolic Accelerator for Molecular Biological Appl
SAPS
• Statistical analysis of protein sequences
ScanProsite
• scan protein sequence(s) against PROSITE
Scratch Protein Predictor
• protein structure & structural features prediction
SecretomeP
• Prediction of non-classical protein secretion
Selectome
• positive selection
Seq2Logo
• Protein sequence logo method
SeqLogos
• Sequence logo from amino acid alignment
Sequence Similarity Maps (SSM)
• data mining of viral isolates
Sequence Variability Server
• Protein sequence variability in MSA
Sequerome
• BLAST similarity search and sequence profiling
SHOPS
• Genomic operon context analysis
ShoRAH
• tools for the analysis of NGS data
SIBsim4
• spliced sequence alignment
SignalP
• Prediction of signal peptide cleavage sites
SIM
• binary sequence alignment
SMART
• genetically mobile domains and domain architecture
SmileMS
• LC-MSMS software for small molecule identification
smirnaDB
• miRNA expression profiles analysis
Soaplab services
• web services interface to bioinformatics tools
SOPMA
• Secondary structure prediction.
SOSUI
• Classification and Secondary Structure Prediction
SSA
• nucleic acid sequence motifs
Strap
• Structural alignments of proteins
STRING
• protein-protein interactions
SugarBind
• pathogen sugar-binding
Sulfinator
• tyrosine sulfation site prediction
SulfoSite
• Prediction of tyrosine sulfations sites
SUMOplot
• Prediction of sumoylation sites in proteins
SUMOsp
• Prediction of sumoylation sites
Superfamily Sequence search
• Search Sequences for SCOP domains
SUPERFAMILY Sequence Search
• Assign SCOP domains to sequence using SUPERFAMILY
SuperTree
• assemble phylogenetic trees
SWISS-2DPAGE
• proteins on 2-D and SDS PAGE maps
SWISS-MODEL Repository
• protein structure homology models
SWISS-MODEL Workspace
• structure homology-modeling
Swiss-PdbViewer
• analyse protein 3D structures
SwissBioIsostere
• bioIsosteres for small molecules
SwissDock
• protein ligand docking server
SwissParam
• topology, parameters for small organic molecules
SwissRegulon
• annotations of regulatory sites
SwissSidechain
• non-natural amino-acid sidechains
SwissVar
• variants in UniProtKB entries
SYFPEITHI
• Prediction of MHC type I and II peptide binding
t
T-Coffee
• sequence and structure multiple alignments
T-Coffee - EBI
• Multiple sequence alignment program
T-Coffee - WUR
• Multiple sequence alignment program
T-REKS
• De novo repeat detection in protein sequences
TagIdent
• protein identification with PI, Mw and tag
TagScan
• genome-wide sequence tag scanner
TargetP
• Subcellular location prediction
TatP
• Twin-arginine signal peptides prediction
TCS
• interaction specificity in two-component systems
TEIRESIAS
• discover patterns in nucleic or aminoacid sequence
TermiNator
• Prediction of N-terminal modification
The Miner Suite
• Tools for data analysis
The PhylOgenetic Web Repeater (POWER)
• Phylogenetic analysis
The Systems Biology Research Tool
• software and API for systems biologists
Three to One
• 3- to 1-letter amino acid converter
Three- / one-letter code
• 3- to 1-letter amino acid converter and inversely
TLS Motion Determination
• Translation/Libration/Screw Motion Determination
TMHMM
• Prediction of transmembrane helices in proteins
TMPred
• membrane-spanning region prediction
TopMatch
• Protein structure comparison
TopPred
• Topology prediction of membrane proteins
TopSearch
• Gateway to protein structures
Translate
• nucleotide sequence translation
TreeGen
• phylogenetic tree from distance matrix
TriFLe
• TRFLP species identification and simulation
tromer
• transcriptome analyser
TRUST
• De novo repeat detection in protein sequences
u
UniMES (UniProt metagenomic samples)
• UniProt Metagenomic and Environmental Sequences
UniParc (UniProt sequence archive)
• UniProt sequence archive
UniPathway
• metabolic pathways for the UniProtKB
UniProtKB
• functional information on proteins
UniProtKB/Swiss-Prot
• protein sequence database
UniRef (UniProt sequence clusters)
• UniProtKB sequence clusters
v
Vertex Cover
• resolves a vertex cover problem
ViralZone
• portal to viral UniProtKB entries
Vital-IT
• life science informatics initiative
VMD - Visual Molecular Dynamics
• Molecular visualization program
w
WebLogo
• Sequence logos
WHAT IF
• Molecular modelling package
Wise2
• Genomic sequence to protein sequence compariso
World-2DPAGE Constellation
• set of 2DPAGE resources
World-2DPAGE Repository
• gel-based proteomics data
WU BLAST
• Sequence similarity search in protein databases
x
xComb
• compute all possible crosslinks between proteins
XplorMed
• Relationship search in MEDLINE abstracts
xQuest
• search cross-linked peptides from complex samples
XSTREAM
• De novo tandem repeat detection
y
YASARA
• Molecular graphics, modeling, simulations
YinOYang
• O-beta-GlcNAc attachment sites in eukaryotes
z
ZFN-Site
• zinc finger nuclease (off-)target sites search