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PROSITE entry PS51831


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51831
Entry name [info] HD
Accession [info] PS51831
Entry type [info] MATRIX
Date [info] 10-MAY-2017 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51831
Associated ProRule [info] PRU01175

Name and characterization of the entry

Description [info] HD domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=109;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=104;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2486947; R2=0.0079611; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=15968.8085938; R2=4.9153047; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1225; H_SCORE=21990; N_SCORE=12.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=535; H_SCORE=18598; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-33; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
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Post-processing [info]

COMPETES_HIT_WITH PS51832; PS51833

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 1'017 in 1'017 different sequences
Number of true positive hits 1'017 in 1'017 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 4
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.61 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] HD
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
1017 sequences

5DNU_CITK8  (A8ADU7), 5DNU_CROS8  (A7MH33), 5DNU_ECO24  (A7ZPA5), 
» more

UniProtKB/Swiss-Prot
False negative sequences
4 sequences

CCA_PSEPK   (Q88QU2), CNS2_CORMM  (G3JF09), PHNZ_UNCHF  (D0E8I5), 
» more

PDB
[Detailed view]
140 PDB

1VJ7; 2O08; 2OGI; 2PAQ; 2PAR; 2PAU; 3GW7; 3NQW; 3NR1; 3U1N; 4BZB; 4BZC;
» more