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PROSITE entry PS51805


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PURL: https://purl.expasy.org/prosite/signature/PS51805

Direct ScanProsite submission
General information about the entry

Entry name [info] EPHD
Accession [info] PS51805
Entry type [info] MATRIX
Date [info] 01-JUN-2016 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51805
Associated ProRule [info] PRU01146

Name and characterization of the entry

Description [info] Extended PHD (ePHD) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=113;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=108;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.0608945; R2=0.0062286; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=21304.7597656; R2=4.8619323; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=874; H_SCORE=25554; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=553; H_SCORE=23993; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-46; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
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Post-processing [info]

COMPETES_HIT_WITH PS50016

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 91 in 83 different sequences
Number of true positive hits 91 in 83 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] ZN_FING
Feature description [info] C2HC pre-PHD-type
Feature key [info] ZN_FING
Feature description [info] PHD-type
Feature key [info] REGION
Feature description [info] Extended PHD domain (ePHD)
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
83 sequences

AF10_HUMAN  (P55197), AF10_MOUSE  (O54826), AF17_HUMAN  (P55198), 
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PDB
[Detailed view]
15 PDB

2LQ6; 4NN2; 5DAG; 5DAH; 5ERC; 6U04; 7D86; 7D87; 7D8A; 7MJU; 8GDX; 8GE0;
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