PROSITE entry PS51794

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PURL: https://purl.expasy.org/prosite/signature/PS51794

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General information about the entry

Entry name [info]	DAC
Accession [info]	PS51794
Entry type [info]	MATRIX
Date [info]	01-MAR-2016 CREATED; 13-FEB-2019 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51794
Associated ProRule [info]	PRU01130

Name and characterization of the entry

Description [info]

Diadenylate cyclase (DAC) domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=152;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=147;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.8847961; R2=0.0084584; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=24708.9218750; R2=9.9220781; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1551; H_SCORE=40098; N_SCORE=15.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=546; H_SCORE=30126; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-23; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='Q';  M= -11, -76,   0,  11, -33, -33, -20, -25, -14,  -5,  10, -16,  -3,  85,   8,   4, -15, -25, -30, -50;
/M: SY='P';  M=  -3, -78,  -1,  20, -33, -37, -61, -38,   5, -19, -62, -10,  76,  39, -16,   3, -21, -24, -77, -34;
/M: SY='E';  M= -14, -76,  16,  76,   4, -26, -18, -56,   0, -23, -22,   2, -63,  -8,  16,   5, -34, -69, -77, -52;
/M: SY='I';  M= -16, -41, -60, -53,  27, -81, -71,  57, -63,  52,  25, -46, -77, -41, -24, -42, -31,  -4,  -1, -51;
/M: SY='R';  M= -10, -78, -16,  10, -27, -31, -28, -24,  20, -33,   0, -15, -71, -29,  86, -25, -39, -38, -74,  -8;
/M: SY='R';  M=  -9, -54,  19,  28, -54, -30,   1, -45,  29, -35, -24,  13, -68, -10,  66,  11, -35, -45, -79, -64;
/M: SY='F';  M=  25, -71, -54, -30,  33, -22,   9,  30, -24,   5,  16, -13, -34, -17, -19, -16,  -9,  14, -49,  10;
/M: SY='L';  M= -39, -71, -81, -47,  45, -83, -45,  29, -51,  66,  -1, -77, -58, -35, -73, -60, -27,   3, -36, -12;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='E';  M=  10, -73,  11,  52, -28, -38,  -3, -58,  17,   0,  -1, -20, -31, -24,   3,  17,  -1, -37, -22,   0;
/M: SY='R';  M= -26, -12,  16,   5, -34, -28,   2, -28,  12,  -1,  18,  -1, -26,  28,  37,   5,  19, -32, -76,  -2;
/M: SY='V';  M= -37, -26, -37, -41,  15, -56, -34,  41, -36,  41,   8,  -5, -76, -69, -61, -34,  -3,  43, -34, -31;
/M: SY='G';  M=  24, -72,  19, -11, -10,  56, -17, -55, -12, -35,  -6, -13,   1, -34, -20,  18, -14, -68, -42, -66;
/M: SY='P';  M= -22, -77,  -4,   8, -28, -38, -23, -51,  12, -13, -28, -20,  68,  11,  24,  15,  -9, -26, -73,  13;
/M: SY='G';  M=  11, -12,   0,   5, -62,  40,   5, -39,   6, -49, -47,  17, -40, -14,   3,  24,   1, -17, -18, -11;
/M: SY='T';  M=  -8, -23,  -1,  -8, -27, -23, -49, -11, -11,  -6, -56,   6, -16,  12,  24,  -2,  51,  17, -50, -36;
/M: SY='P';  M= -18, -74, -20,   1,  27, -54, -66,  25,  -3,  15,  -7,  -5,  37, -12, -11,   3, -26,  10,   5, -34;
/I:         I=-13; MD=-33;
/M: SY='F';  M= -52, -79, -15,  18,  34, -39,  10, -11,   3,   7, -23, -14, -44, -45,   1,   7, -22, -17,  33,   8; D=-13;
/I:         I=-13; MD=-33;
/M: SY='K';  M= -23, -37,   2, -12,   1, -11,  -8, -17,  17, -21,   2, -14, -25,   7,  16,  16,  -7, -32, -79,  -7; D=-13;
/I:         I=-13; MD=-33;
/M: SY='I';  M= -44, -83, -16, -29,  -5, -13, -44,  23,  -9,   4, -39,   1, -29, -24,  -3,  -1, -23,  -1, -26, -14; D=-13;
/I:         I=-13; MD=-33;
/M: SY='M';  M= -42, -37, -25, -25,   0, -31, -26,   1,  -4,   6,   7, -14, -53, -16, -31, -14, -29,  -6, -43, -72; D=-13;
/I:         I=-13; MD=-33;
/M: SY='F';  M= -54, -29, -67, -42,  -3, -55, -54, -25, -23, -17, -27, -22, -42, -19,  -9, -39, -37,  -8, -58, -52; D=-13;
/I:         I=-13; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='I';  M= -44, -94, -35, -26, -78, -40, -52,  33, -24,  -2, -33, -85, -39, -56, -18, -28, -21,   5, -97, -43; D=-13;
/I:         I=-13; DM=-33;
/M: SY='D';  M= -56, -88,  35,  31, -61, -38, -52,  12,  -3,  -7, -32,   0, -46,  -3, -26, -41, -23, -35, -91, -35; D=-13;
/I:         I=-13; DM=-33;
/M: SY='E';  M=  32, -37, -18,  43, -80, -64,  -1, -35, -25, -22,   2, -27,   0, -15, -24,  11,  -9, -43, -87, -74; D=-13;
/I:         I=-13; DM=-33;
/M: SY='I';  M= -43, -45, -54, -53,   3, -83, -73,  62, -75,  53,  15, -53, -50, -71, -76, -25, -37,  24, -72, -27;
/M: SY='W';  M=  15, -11,  18,  25, -11, -60, -64,  -1, -20, -20, -24, -29, -70, -22,  36,  -1,  -7,  28,  38, -21;
/M: SY='D';  M= -16, -75,  37,  30,  -1, -30, -18,  16,  19,   6, -11,  -4, -68,  17,  -5, -38,   1, -33,  -4,  -9;
/M: SY='A';  M=  64,  -8, -33, -65, -37,  28, -68,  -1, -64, -13, -40, -60, -69, -61, -26,  20, -17, -15,   6, -20;
/M: SY='C';  M=  18,  57, -56, -51,   3, -46, -28,  27, -43,  21, -24, -35, -76, -35,  -6, -54, -17,  46,  16, -48;
/M: SY='E';  M=  -6, -76,  30,  46,  -8, -44,  39, -48,   9, -26,  -6, -11, -67,  30,  17, -21,  -8, -37,  16,  12;
/M: SY='G';  M= -27, -51,   0,  19, -36,  31,  12, -36,   2, -43, -27,  27, -68,  12,  28,   9,  -3, -16, -13,  16;
/M: SY='M';  M=   8, -34, -76, -38,  -3, -77, -64,  18, -61,  51,  61, -71, -34, -26,  33, -66, -36,  -8, -71, -12;
/M: SY='S';  M=  30, -32, -56,  38, -42, -18, -30, -21, -12, -24, -20, -54, -65,  16, -38,  61, -19, -14, -77, -43;
/M: SY='G';  M=  -2, -60,   3,  27, -63,  35, -11, -62,   8, -44, -50,  12,  -2,  31,  33,  -3, -16, -55, -75,  -3;
/M: SY='Q';  M=   7, -75,  -5,  -5, -76,  -8,  23, -62,  36, -52, -36,   2, -42,  51,  47,   2,  13, -42, -78, -64;
/M: SY='K';  M= -30, -54, -41, -51, -53,   2,  38, -43,  62, -68, -50,  11,  28,   2,  55,  -6, -59, -73, -15, -38;
/M: SY='H';  M= -32, -15, -67, -42, -20, -38,  58,  51, -25, -22,   4, -34, -31, -52, -33, -14,  51,  21, -77,   1;
/M: SY='G';  M= -50, -77, -64, -75, -80,  99, -70, -86, -68, -56, -73, -22, -14, -67, -53, -50, -67, -57, -74, -44;
/M: SY='A';  M=  73,  16, -65, -46, -41,  12, -68, -48, -62, -34, -46, -58, -66, -61, -45, -11,  49, -43, -76, -25;
/M: SY='L';  M=  -7, -10, -80, -74, -11, -80, -68,  22, -74,  73,  29, -75, -78, -69, -73, -52,  17, -39, -71, -21;
/M: SY='I';  M= -41, -31, -84, -81,  53, -85, -76,  78, -77,  15,  10, -76, -78, -76, -78, -71, -38,  24, -65,  -3;
/M: SY='V';  M=   1,  -6, -79, -36, -31, -70, -81,  30, -73, -12, -43, -75, -76, -73, -75, -59, -21,  87, -83, -61;
/M: SY='I';  M= -26, -56, -85, -80,  39, -84, -77,  70, -77,  33,  12, -78, -78, -75, -77, -72, -60,  33,  29, -32;
/M: SY='E';  M= -11, -35,  14,  55, -76,  46, -62, -45, -30, -65, -67, -31, -14,  18, -46,  -3,  16,  -3, -23, -40;
/M: SY='D';  M= -39, -35,  53,  -2, -44, -21,  -8, -57,  13, -14, -35,  32, -24,   7,  51, -18,  -8, -33,   6, -29;
/M: SY='D';  M= -12, -74,  39,  23, -52,  -3,  20, -45,  17, -62, -66,  24,   4,  16,   6,  14,  24, -42, -81, -25;
/I:         I=-19; MI=0; MD=-49; IM=0; DM=-49;
/M: SY='D';  M= -10, -74,  44,  18, -59, -46,  16,   3,   7, -36,  13,  18,   4,   9,  -8,  -1,  16,   1, -82, -33;
/M: SY='S';  M= -40, -73,  21,  26, -44,  11, -39, -48,   4, -18, -64,  21,  24,   4, -10,  44,  -3, -27, -79, -22;
/M: SY='L';  M=  -4, -71, -38, -35, -27, -49,  14,  10, -33,  55,  11, -70,  -7, -49, -21, -37, -12,  22,   9,   0;
/M: SY='D';  M=  -9, -76,  42,  33, -64,  -3, -15, -50,  24, -13, -10, -19, -10,  41,  13,   0, -15, -42, -78, -32;
/M: SY='D';  M= -26, -76,  41,  33,  -5, -24,  33, -40,   4, -21, -23,  28,   6,  -2,  27,   2, -29, -47, -78, -19;
/M: SY='Y';  M= -50, -58, -64, -34,  27, -44, -35,  47, -50,  31,  -3, -45,  -7, -47, -71, -48, -25,   8,   5,  70;
/M: SY='I';  M=  26,  11, -63, -21,  -3, -27, -70,  48, -35,  11,   4, -47, -51, -31, -28,  13,   1,  14, -42, -29;
/M: SY='N';  M= -16, -74,  45,  30, -63, -23,  22, -40,  13, -49, -46,  48, -46,  35, -15,  10,   7, -45, -14, -45;
/M: SY='P';  M= -14, -74, -22, -49, -64,  26, -24, -25, -23, -46, -31,  18,  54,  44, -21,  27,  37, -66,  -7, -68;
/M: SY='G';  M=  -6,  17, -65, -34,   5,  76, -12, -55, -39, -37,  15, -25, -31, -63, -70,  11, -38, -35, -70,   9;
/M: SY='F';  M= -31, -72,   8,   6,  38, -28, -34,  14, -12, -14, -18,  -9, -22, -17, -17, -25,  29,  33,  18,  -8;
/M: SY='P';  M= -15, -15,   4,  12, -26,  -1, -41,  -8,  20,  -9,  -6,  -9,  42,   3,  33,  -9, -28, -19, -76, -29;
/M: SY='I';  M= -64, -30, -72, -29, -36, -66,  31,  59, -29,  46,  23,  17, -42, -19, -43, -55, -46,   3, -41, -29;
/I:         I=-33; MI=0; MD=-84; IM=0; DM=-84;
/M: SY='D';  M= -31, -77,  72,  17, -54, -32,  28, -55,  -3, -57, -41,  55,  40, -20, -30, -12, -33, -60, -88, -55;
/M: SY='A';  M=  54,  47, -67, -16, -26, -10, -68,  -4, -24, -13, -36, -61, -52, -40,  18,  17, -13,   6,  -6, -65;
/M: SY='E';  M= -15,  -9,  28,  38, -54, -69,  -6, -20,  29,  -2, -29,  16,   0,   8,  26, -16,  -3, -26, -80, -48;
/M: SY='V';  M= -29, -72, -28, -59,  40, -18, -72,  48, -47,  24, -23, -51, -42, -72, -37, -50, -53,  50, -68,   7;
/M: SY='S';  M= -27,  -7, -21, -11, -24, -37, -13, -66, -12, -17, -15,  33, -66, -45,  -4,  69,  42, -49, -80, -25;
/M: SY='P';  M=  14, -24,  24,  16, -75, -46, -32, -52,   6, -46, -50,  16,  56, -23,  11,  29,  -6,  -9, -82, -57;
/M: SY='E';  M= -17, -35,  23,  59, -74, -50,  -4, -24,   1, -36, -16, -13,  26,  22,  14,  -5,   2, -15, -80, -40;
/M: SY='L';  M= -13, -72,   1, -14,  -1, -55, -63,   5,   1,  56,   6,   4, -49, -60,  17, -33, -24, -28, -72, -13;
/M: SY='L';  M= -40, -72,   9,  -7, -19, -59, -37,  38, -35,  62, -14,   4, -76, -65, -70, -41, -36,  -2, -74, -23;
/M: SY='E';  M= -30, -58, -20,  39,  -8, -38, -24,   2,   7,  14, -12, -29, -30,  20,  29, -25, -44,   1,  11,  28;
/M: SY='E';  M=   3, -70,   7,  51, -33, -33, -26, -71, -51, -54, -50,  43, -16, -13, -14,  46,  29, -44, -82, -41;
/M: SY='I';  M= -26, -72, -40, -74, -13, -58,  10,  72, -72,  39, -13,   6, -75, -69, -74, -30,  -6,  11, -75, -55;
/I:         I=-19; MD=-47;
/M: SY='F';  M= -16, -35, -91, -86,  94, -87,  -3,   2, -46, -11, -39, -81, -89, -86, -62, -77, -38, -42,  31, -20; D=-19;
/I:         I=-19; MD=-47;
/M: SY='Y';  M= -56, -58,  10,  10,  27, -44,  -7,   1,  19, -41, -27,   8, -48,   2, -33, -25, -17, -35,  16,  29; D=-19;
/I:         I=-19; MD=-47;
/M: SY='P';  M= -26, -91, -31, -20, -63, -56,  -6, -66,  32, -89, -80,   6,  60, -13, -39, -23,   6, -46, -94, -66; D=-19;
/I:         I=-19; MI=0; MD=-47; IM=0; DM=-47;
/M: SY='N';  M= -34, -82, -11,  36, -76,  -4,  -3, -56,  -9, -55, -45,  48, -76, -12, -12,  -6,  -9,  -5, -86,  10; D=-19;
/I:         I=-19; DM=-47;
/M: SY='S';  M=   2, -74, -72, -73,  30, -55, -30, -26, -71,  15, -61,  -9, -78, -68, -68,  52,  34, -61, -79, -32; D=-19;
/I:         I=-19; DM=-47;
/M: SY='P';  M=  35, -17, -65, -51, -23, -61, -67, -38, -41, -48, -17, -61,  86, -60, -26,  40,  15, -37, -78, -56;
/M: SY='L';  M= -12, -37, -68, -47, -25, -24, -62, -29,  27,  55,   2, -18, -73,  35, -16,  13, -11, -29, -73, -58;
/M: SY='H';  M= -65, -76, -65, -62, -38, -53, 114,  30, -62,  10,  55, -32, -72,  -2, -14, -63, -24,  -1, -85, -46;
/M: SY='D';  M= -68, -81, 119, -31, -88, -64, -53, -86, -54, -84, -83, -35, -67, -54, -40, -56, -57, -83,-103, -70;
/M: SY='G';  M= -49, -77, -65, -76, -81, 102, -71, -88, -69, -57, -39, -51, -68, -67, -57, -50, -68, -82, -74, -77;
/M: SY='A';  M=  93, -20, -68, -62, -75,  -2, -70, -51, -63, -66, -41, -62, -67, -60, -68, -33, -37, -16, -76, -71;
/M: SY='V';  M=  -9, -69, -82, -77,  44, -81, -77,  44, -75,  12,  15, -75, -77, -75, -76, -66, -12,  68, -72, -50;
/M: SY='I';  M= -60, -72, -82, -78, -34, -86,   1,  71, -75,  21, -26, -76, -77, -47, -76, -70, -57,  63, -44,   7;
/M: SY='I';  M= -62, -73, -85, -81,  -6, -88, -81,  82, -77,  26, -19, -78, -77, -75, -79, -72, -48,  51, -75, -55;
/M: SY='D';  M= -22, -74,  59,  -8, -65, -33, -26, -56,  -4, -68, -30,  23, -67,   3,  52,  30,  23, -45, -83, -36;
/M: SY='N';  M= -13, -54,  33,  15, -76,  40, -59, -29,   1, -70, -41,  41,  18, -13,  10,   5, -19, -28, -80, -30;
/M: SY='D';  M= -35, -75,  74,   8, -40,  14, -13, -50, -13, -60, -35,  54, -68,  -6,  -4,  -8,  -5, -73, -83,   1;
/I:         I=-26; MD=-67;
/M: SY='G';  M= -28,-100, -92, -98, -39,  62, -43, -53, -76, -31, -62, -47, -96, -51, -70, -78, -91, -79, -97, -60; D=-26;
/I:         I=-26; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='R';  M= -48, -75, -21, -10, -68, -53,   1, -14,  44, -40, -23,  -6, -69,   5,  66, -17,  24,   7, -33, -16;
/M: SY='I';  M= -62,  45, -80, -54, -26, -85, -77,  78, -29,  13, -10, -73, -76, -15,  -5, -69, -30,  36, -77, -58;
/M: SY='H';  M=   7, -41, -58,  -3, -21, -57,  44,  31, -11,  18,  11, -66, -73,  -5, -16, -44, -17,  43, -46,  -3;
/M: SY='A';  M=  66, -15, -64, -34, -59,  -1,  -5, -39, -22, -26, -48, -57, -68, -29,   6,  43, -41, -16, -75, -15;
/M: SY='A';  M=  72, -12, -70, -48,  29, -32, -66,  -1, -29, -25, -28, -63, -70, -18, -14, -12, -14, -19, -29,   6;
/M: SY='G';  M=  36, -34, -64, -48, -37,  73, -26, -75, -22, -58, -19, -31, -42, -51,  13,  10, -36, -43, -75, -48;
/M: SY='C';  M=  11, 100, -47, -66, -56, -22, -31, -31, -58, -58, -60,  22, -50, -45,  33,   2,  -4,  35, -87, -69;
/M: SY='Y';  M= -33, -75, -38, -47,  20, -59,  35,  54, -66,  -6,   8, -69, -76, -26,  -6, -66, -24,  29, -23,  68;
/M: SY='L';  M= -52, -71, -81, -73,  20, -84,   5,  14, -74,  78, -14, -78, -53,  -2, -51, -73, -63, -14, -69, -33;
/M: SY='P';  M= -28, -38,  51,  -7, -60, -53, -14, -48, -21,  -2, -12, -11,  90, -43, -16, -16, -26, -54, -82, -71;
/M: SY='L';  M= -17, -14, -71, -59, -41,  24, -68,   8, -68,  40,  11,  -6,  17, -18, -53, -16,   4,  28, -76, -23;
/M: SY='S';  M=  -6, -71,  20, -17, -73, -30, -13, -16, -33, -31, -40, -24,  48,   1, -22,  60,  33, -37, -82, -67;
/M: SY='D';  M=  21, -72,  39,  21, -73,  -3,  32, -70,   0, -32, -36,  -1, -31,  16,  -6,  29,  -2, -24, -81, -22;
/M: SY='N';  M=  -2, -73,  14,  14, -45, -22,  -6, -23,  16, -71, -49,  53,   7,  12,  27,  20, -10, -12, -82, -66;
/I:         I=-13; MD=-32;
/M: SY='S';  M=   4, -75,  24,   7, -52, -17, -13, -31,  -8, -45, -46,  22,  25,   3, -11,  37,  13, -44, -83, -30; D=-13;
/I:         I=-13; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='D';  M= -26, -78,  54,  17, -35, -23, -17,  -2,  -7, -26,  -6,  22, -59, -16,  -8,  -9,  -8,   2,  10, -31; D=-13;
/I:         I=-13; DM=-32;
/M: SY='L';  M= -48, -30, -70,  14, -48, -18,  -8,  41, -34,  44, -21, -29,  26, -19, -70, -42, -17,  10, -77, -50; D=-13;
/I:         I=-13; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='P';  M= -19, -76,  41,   4, -52, -26, -22, -20,  -4, -49, -37,   6,  71, -11, -41,  22,  20, -42, -81, -25;
/M: SY='K';  M=   1, -74,  18, -12, -56, -15,  -6, -52,  37, -33,   3, -20,  32,  17,  26,  23,  -4, -20, -46, -46;
/M: SY='W';  M=   5, -52,  -1,  32, -41,  32, -16, -52,   6, -46, -51, -15, -66,  12,   3,  31,   1, -69,  58,  -7;
/M: SY='M';  M= -60, -72, -73, -48,  36, -36,  19, -30, -37,  43,  55, -66, -76, -61,  30, -32,  20, -16, -63,  37;
/M: SY='G';  M= -50, -77, -32, -74, -50, 101,  -8, -90, -69, -85, -74, -50, -68, -66, -76, -34, -67, -83, -74, -75;
/M: SY='T';  M=  37, -64, -46, -63, -46, -13, -66, -47, -62,  11,  39, -55, -65, -60, -67,  24,  77, -51, -80, -63;
/M: SY='R';  M= -66, -83, -41, -51, -76, -43, -53, -82,  -7, -62, -64, -56, -75, -41, 113, -60, -42, -76, -76, -63;
/M: SY='H';  M= -69, -80, -55, -56, -20, -71, 141, -80, -59, -56, -53, -26, -71, -49, -54, -33, -66, -81, -84,  42;
/M: SY='R';  M= -16, -76, -61, -46, -68, -70, -26, -38, -14, -11,  35,  43, -26, -26,  88, -37, -13, -47,  16, -39;
/M: SY='A';  M=  76, -62, -62, -59, -73, -51, -65, -66, -60, -69, -63, -34, -39, -56, -65,  59,  23, -42, -78, -41;
/M: SY='A';  M=  92, -27, -68, -62, -75,  11, -70, -47, -63, -67, -33, -61, -67, -60, -68, -35, -27, -32, -76, -71;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='L';  M=  28, -58, -48,  -3, -19, -61, -16,  42, -31,  44,  15, -54, -74, -33, -12, -53, -59,   6, -72,  -7;
/M: SY='G';  M=   2, -75, -22, -11, -77,  69, -12, -65, -10, -61, -68, -16, -69, -35,  55,  -8, -23, -55, -76, -42;
/M: SY='I';  M= -33, -72, -56, -76,  25, -82, -69,  63, -73,  30,  40, -73, -76, -71, -74, -67,  13,  18, -64,  38;
/M: SY='S';  M=  21,  22, -59, -60, -70, -57, -15, -64, -59, -33, -62, -41, -64, -32, -64,  72,  69, -35, -84, -66;
/M: SY='E';  M=   6, -76, -35,  76, -35, -55,  -2, -58,  31, -22, -63, -41, -63,  20,  12, -15, -31, -32, -13, -22;
/M: SY='Q';  M= -11, -21,  24,  32, -69, -42, -16,  -8,   8, -25, -19, -10, -68,  50,  25,  -3,  -5,   8, -77,  -7;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='T';  M= -42,  22, -31, -61, -10, -59,  46, -39, -33, -24, -26, -23, -16, -59, -44,  46,  76, -33,  -7,  -5;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='D';  M= -52, -31,  90,   0, -83,  16,  -3, -80,  -5, -81, -75,  41, -11, -13, -44, -19, -35, -42, -92, -70;
/M: SY='A';  M=  66,  51, -31,  -6, -45, -20, -15, -52, -14, -41, -60, -13, -41, -41, -32,  12, -41,  12, -79, -46;
/I:         I=-42; MI=0; MD=-106; IM=0; DM=-106;
/M: SY='V';  M=  -9, -19, -77, -70,  -1, -78, -73,  43, -15,  30,  16, -71,   3, -25, -36, -21,  -3,  44,  11, -47;
/M: SY='V';  M=  48,  40, -47, -69, -39, -29, -76,  31, -69, -30, -27, -66, -60, -68, -73, -23,  26,  53, -81, -64;
/M: SY='I';  M= -40, -72, -83, -58,  18, -86, -80,  72, -76,  25, -38, -77, -77, -42, -77, -71, -57,  58, -74, -54;
/M: SY='V';  M=  12,  -9, -75, -54,  -7, -76, -78,  42, -38, -29, -46, -69, -73, -71, -72, -39,  36,  71, -80, -60;
/M: SY='V';  M= -33, -67, -83, -77, -52, -84, -83,  31, -75,   7, -40, -77, -78, -76, -76, -66, -26,  91, -84, -60;
/M: SY='S';  M= -43, -65, -58, -45, -70, -53, -61, -13, -59, -57, -64, -15, -66, -52, -63, 100, -38,  12, -83, -65;
/I:         I=-42; MI=0; MD=-106; IM=0; DM=-106;
/M: SY='E';  M= -24, -77, -16,  90, -81, -38, -26, -80, -10, -59, -69, -32, -59,  37, -51,  38, -55, -73, -80, -70;
/M: SY='E';  M= -35, -76,  -3,  89, -79, -68, -55, -77, -12, -73,   0, -53, -59, -16,  10,  37,   0, -63, -81, -69;
/M: SY='T';  M= -46, -70,  48, -53, -73,  12, -60, -52, -36, -57,  -4,  11, -65, -55,  38,  11,  73, -45, -85, -67;
/M: SY='G';  M= -47, -36, -30, -43, -80,  91, -66, -59, -50, -81, -46,   1, -69, -10,   3,  -9, -48, -50, -76, -74;
/M: SY='P';  M= -23, -52,   1, -11, -67, -32,   2,  14,  14, -32,  18, -21,  26,   8,  20,  15,  25,  15, -79, -30;
/M: SY='I';  M= -50, -72, -83, -78, -33, -86, -82,  78, -49, -12,  -4, -75, -76, -73, -24, -54, -46,  67, -78, -58;
/M: SY='S';  M= -21, -67,  -1, -30, -48, -48, -16, -40, -39, -35, -28, -20, -65, -52,  22,  79,  44, -26, -82, -64;
/M: SY='V';  M= -38, -52, -81, -76,   3, -83, -72,  50, -53,  38,   8, -76, -47, -72, -53, -60, -25,  54, -14,  28;
/M: SY='F';  M=  43,   9, -57, -37,  62, -56, -30,  12, -35, -35,  -7, -67, -75, -31, -37, -23, -21,   6,  -8,  49;
/M: SY='H';  M= -43, -77, -17,   8,  -2, -55,  40, -12,  34, -22,   5, -57,  -3,  37,  30, -19, -22,   0, -15,  40;
/M: SY='N';  M= -33, -75,  51,  13, -70,  33,   5, -80,   2, -72, -70,  66, -58,  -7,  30, -18, -57, -54, -84, -38;
/M: SY='G';  M= -41, -77,   7,  -3, -49,  88, -66, -64, -33, -38, -71, -10, -12, -47, -33, -27, -50, -78, -76, -74;
/M: SY='K';  M= -14, -75,  12,  29, -32, -25,   8,   0,  44, -24, -22,  16, -24,  12,  22, -17,  -1, -23, -77, -37;
/M: SY='I';  M= -22, -21, -24,   6,  23, -66, -52,  40, -18,  36,  30,  -8, -12, -63,  -3, -46, -40,   9, -32, -23;
/M: SY='Y';  M= -38, -28, -14,  -2, -11, -49,   6,  34, -10,  -7, -42, -32, -40,  22,   5, -18,  26,  16, -67,  49;
/I:         I=-36; MD=-90;
/M: SY='R';  M= -10, -75,   2,  10, -32, -34,   9,  -8,   7,   2, -26, -17,   6, -16,  37,  -6,  20,  -2, -37,   3; D=-36;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='N';  M= -41, -18,  29,  26, -24,  -3, -13,  -5, -18,   3, -17,  43,  15,  -1, -12,  -6,   3, -23, -79, -21;
/M: SY='I';  M= -30, -38, -51,   5,   0, -61, -34,  41, -23,  40,   8, -41, -51, -20,  16, -38, -24,  13,  25,  -1;
/M: SY='S';  M= -19, -40,  34,  30, -75, -39,  -4, -35,  25, -57, -51,   8,  19,   1,   2,  38,  22, -38, -81, -34;
/M: SY='P';  M= -11, -43,  41,  44, -52, -44, -19, -52, -18, -55, -54,   6,  59,  17,   8,   7, -11, -47,  -1, -37;
/I:         E1=0; IE=-380; DE=-380;

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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	74 in 74 different sequences
Number of true positive hits	74 in 74 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Taxonomic range [info]	Archaea, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Feature key [info]	DOMAIN
Feature description [info]	DAC
Version [info]	3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

74 sequences

CDAA_BACSU  (Q45589), CDAS_BACSU  (O31854), CDAS_BACT1  (D5TM67),

DACA_LISM4  (A0A0H3GM48), DACA_LISMO  (Q8Y5E4), DACB_MYCGE  (P47351), 
DACB_MYCPN  (P75528), DACZ_HALVD  (D4GZM5), DACZ_METJA  (Q58408), 
DISA_ACET2  (A3DGC7), DISA_ACIC1  (A0LRE3), DISA_BACAA  (C3P9M9), 
DISA_BACAC  (C3LJ56), DISA_BACAH  (A0R8F5), DISA_BACAN  (Q81VV7), 
DISA_BACC0  (B7JK90), DISA_BACC1  (Q73FC3), DISA_BACC2  (B7ISZ3), 
DISA_BACC3  (C1ET13), DISA_BACC4  (B7HJ22), DISA_BACC7  (B7HQR7), 
DISA_BACCQ  (B9IZG8), DISA_BACCR  (Q81J64), DISA_BACCZ  (Q63HB6), 
DISA_BACHK  (Q6HPT4), DISA_BACLD  (Q65PD4), DISA_BACMK  (A9VN96), 
DISA_BACP2  (A8F956), DISA_BACSU  (P37573), DISA_BEUC1  (C5C1B3), 
DISA_CARHZ  (Q3A9N3), DISA_CLOAB  (Q97EC6), DISA_CLOB1  (A7FZ95), 
DISA_CLOB6  (C3KVS9), DISA_CLOB8  (A6LPN7), DISA_CLOBA  (B2UY85), 
DISA_CLOBB  (B2TIF1), DISA_CLOBH  (A5I7N4), DISA_CLOBJ  (C1FNB1), 
DISA_CLOBK  (B1IGI2), DISA_CLOBL  (A7GJA2), DISA_CLOBM  (B1KTB1), 
DISA_CLOD6  (Q18CB2), DISA_CLOK5  (A5N4M2), DISA_CLOPE  (Q8XHQ0), 
DISA_CLOPS  (Q0SQB6), DISA_CLOTE  (Q890L8), DISA_COREF  (Q8FMH9), 
DISA_CORGB  (A4QH66), DISA_CORGL  (Q8NMB2), DISA_CUTAK  (Q6AAZ9), 
DISA_FRAAA  (Q0RBN2), DISA_FRACC  (Q2J537), DISA_FUSNN  (Q8RGW9), 
DISA_HALH5  (Q9KGG0), DISA_KINRD  (A6W5K2), DISA_MYCA1  (A0QAA9), 
DISA_MYCBO  (Q7TW52), DISA_MYCBP  (A1KPS2), DISA_MYCBT  (C1AI45), 
DISA_MYCPA  (Q743W9), DISA_MYCS2  (A0R564), DISA_MYCTA  (A5U8R1), 
DISA_MYCTO  (P9WNW4), DISA_MYCTU  (P9WNW5), DISA_PARS2  (A8LF79), 
DISA_SHOC1  (Q5WLT9), DISA_STRAW  (Q82EA6), DISA_STRCO  (Q9X8L6), 
DISA_STRGG  (B1VSK3), DISA_SYMTH  (Q67JP1), DISA_THEMA  (Q9WY43), 
DISA_THENN  (B9K6S9), DISA_THEP1  (A5IKM1)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

PDB
[Detailed view]

57 PDB

3C1Y; 3C1Z; 3C21; 3C23; 4RV7; 4YVZ; 4YXJ; 4YXM; 6HUW; 6HVL; 6HVM; 6HVN;
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