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PROSITE entry PS51747


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51747
Entry name [info] CYT_DCMP_DEAMINASES_2
Accession [info] PS51747
Entry type [info] MATRIX
Date [info] 01-FEB-2015 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00702
Associated ProRule [info] PRU01083

Name and characterization of the entry

Description [info] Cytidine and deoxycytidylate deaminases domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=121;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=116;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2398152; R2=0.0085807; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=15402.6152344; R2=4.1938214; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=905; H_SCORE=19198; N_SCORE=10.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=497; H_SCORE=17487; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-23; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 415 in 273 different sequences
Number of true positive hits 415 in 273 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.76 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] CMP/dCMP-type deaminase
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
273 sequences

AB3CA_FELCA (Q4VDN5), ABC3A_HUMAN (P31941), ABC3B_HUMAN (Q9UH17), 
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UniProtKB/Swiss-Prot
False negative sequences
1 sequence

TAD3_ARATH  (F4KH86)

		
PDB
[Detailed view]
100 PDB

1AF2; 1ALN; 1CTT; 1CTU; 1JTK; 1MQ0; 1OX7; 1P6O; 1R5T; 1RB7; 1TIY; 1UAQ;
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