PROSITE entry PS51728
View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS51728 |
| Entry name [info] | RTT109_HAT |
| Accession [info] | PS51728 |
| Entry type [info] | MATRIX |
| Date [info] |
01-JUL-2014 CREATED;
13-FEB-2019 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51728 |
| Associated ProRule [info] | PRU01064 |
Name and characterization of the entry
| Description [info] | Rtt109-type histone acetyltransferase (HAT) domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=373; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=368; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2920060; R2=0.0058039; TEXT='-LogE'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=63463.1445312; R2=15.7928858; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=1673; H_SCORE=89885; N_SCORE=12.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=726; H_SCORE=74929; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-43; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='S'; M= -30,-106, 38, -29,-105, -10, -7, -55, -87, -20, -32, 14, -8, 14, 13, 52, 22, -66,-115, -21; /M: SY='L'; M= -22,-103,-109, -53, 9, -63, 31, -9, -20, 74, 4,-105,-111, -39,-101, -43, -30, -46,-104, -84; /M: SY='L'; M= -31, -25, 7, 17, -49, -44, -96, -13, -10, 31, -7, -11, 3, -15, 20, -7, -5, 15,-111, -95; /M: SY='E'; M= -16, 6, 42, 60,-104, -58, -35, -38, -10, -10, -96, -20, -98, 17, -17, 32, -29, -99,-112, -17; /M: SY='R'; M= 20, -29, -94, -1, -26, -59, 14, -25, -2, 25, -86, 9,-104, 11, 28, 25, -20, -54,-106, -5; /M: SY='L'; M= -43,-103, -40, -23, -82,-110, 12, 9, -21, 70, -71,-102,-109, -96,-101, 18, -29, -19, 27, -88; /M: SY='S'; M= 46,-101, -49, -20, -45, -28, -97, -52, 11, 24, -88, -91, 5, 4, -93, 47, -14, -89,-109, -97; /M: SY='A'; M= 38,-105, 13, 37, -48, -94, -32,-106, 31, -72, -99, -23, 23, 21, -51, 36, -43,-100,-110, -39; /M: SY='V'; M= 35, -11, -45, -20, -46, -58, -28, -11, -15, -35, -87, -1, 4, -48, -3, -7, 9, 48,-111, -13; /M: SY='L'; M= -96,-103,-112, -41, -40,-115,-102, 23, -54, 79, -66,-109, -48,-101,-105, -3, -45, -13,-105, -88; /M: SY='P'; M= 7,-116, -34, -51,-111, -51,-102, -13, -96, -48, -97,-102, 113, -97, -56, -22, -90, -36,-112,-110; /M: SY='K'; M= -28,-108, -42, 47, -63, 31, -24,-105, 51, -53, -98, -13, -20, 18, -29, -14, 14, -30,-110,-100; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='D'; M= -13,-106, 61, -47,-110, 52, -94,-106, -10, -38,-102, 25, -15, -90, -97, 12, 18, -40,-116,-104; /I: I=-42; MD=-106; /M: SY='H'; M= -24, -20, -3, 9, -57, 6, 60, -34, -32, -13, -24, -24, 5, -32, 33, -21, -9, 25,-114, -46; D=-42; /I: I=-42; MD=-106; /M: SY='T'; M= -22, -9, -4, 26, -48, -27, -4, -44, 37,-105, -98, 26, -7, 24, -18, 29, 38,-100,-113, -99; D=-42; /I: I=-42; MI=-106; IM=-106; DM=-106; /M: SY='F'; M=-100, -37,-110, -22, 90,-113, -96, -30,-105, 34, -6,-106, -50,-106,-104, -55, -4, -7, -83, 46; /M: SY='Q'; M= -27,-107, 19, 40, -31, -56, 26, -66, 24,-104, -97, -4, -97, 41, 34, 8, 34, -62,-112, -95; /M: SY='V'; M= 9, -18,-109,-104, -17, -67,-103, 41,-102, 39, -74, -22, -45, -23, -32, -52, -32, 48,-105, 1; /M: SY='Y'; M= -99, -12, -28,-100, 34, -62, 67, 15, -52, 28, -78, -97,-110, -42, 4, -56, -23, -21, -89, 76; /M: SY='H'; M= -25, -24, -36, -36, -92,-101, 119, -96, -52, -63, -87, -3,-103, 5, -89, -1, 0, 16,-112, 43; /M: SY='L'; M= -96,-103,-111, -55, -18,-116,-103, 39,-107, 71, -67, -12,-112,-103,-107,-103, -14, 21, -10, -18; /M: SY='Q'; M= -5, -1, -44, -30, -1, -58, 33, -94, -10, -71, -91, -33,-102, 75, 16, 44, -47, 18,-108, -33; /M: SY='S'; M= -51, -31, -28, -36,-103, -89, -94, -98, -89, -67, -97, -12, -43, -86, -95, 85, 73, -39,-117, -99; /M: SY='P'; M= -5,-107, -19, -31,-102, -98, -1, 0, 10, -13, -90, 24, 63, 27, -36, 14, -5, 0, 21, -97; /M: SY='P'; M= -11,-114,-100, -49, -7,-101, -25, -94, -96, -22, -9,-103, 112, -98,-105, -38, -10, -15, -4,-102; /M: SY='T'; M= -5, -33, -94, -29, 7,-100, -95, -58, 24, -43, -92, -87, 3, -20, 42, 17, 65, -13,-108, -34; /I: I=-21; MI=0; MD=-53; IM=0; DM=-53; /M: SY='K'; M= -42,-110, -17, 33,-109,-103, -3, -66, 65,-105, -97, -24, 28, -13, 56, -22, -38, -16,-110, -98; /M: SY='C'; M= -37, 89, -27, -23,-100, -98, 15, -99, -20, -46, -95, -42,-101, -91, -15, 46, 69, -60,-116, -9; /I: I=-29; MD=-75; /M: SY='H'; M= -44,-112, 15, -20, -56,-103, 78, -34, 17, -11, -95, -26, 52, -3, -24, 9, 7,-102,-119, -95; D=-29; /I: I=-29; MI=0; MD=-75; IM=0; DM=-75; /M: SY='P'; M= 42,-109, -3, -37, -49, -37,-102, 6, -52, -41, -97, 16, 58, -4, -53, -39, 11, -56,-116,-106; D=-29; /I: I=-29; DM=-75; /M: SY='L'; M= -63, -31, -51,-106, -41, -67, 52, 16, -38, 60, -75, -9,-115, -23,-105,-104, -34, -5,-111, -13; D=-29; /I: I=-29; DM=-75; /M: SY='F'; M= -54,-107,-116,-113, 84,-116,-103, 28,-109, -4, -81, -30,-116, -41,-109,-103, -14, 26, 2, 34; D=-29; /I: I=-29; DM=-75; /M: SY='H'; M= -16, 3, -22, -11, -8, -23, 56,-100, -62, -43, -94, -20, 45, -2, -48, 52, 22, -41,-108, 12; /M: SY='P'; M= 13,-111, -33, -46, -17, -59, 0,-101, 25, -36, -96, -47, 90, 6, -92, 12, -89, -58, 27, -1; /M: SY='P'; M= 25,-106, -94, -48, 19, -96, 25, -98, 19, -8, -31, 8, 63, -21, 2, 29, -50, -96,-105, -36; /M: SY='P'; M= 20,-106, -3, -25,-104, -69, 7, 0, 1, -32, -93, 3, 68, -20, -16, 26, 6, -40,-111, -40; /M: SY='Q'; M= -18,-109, 3, -1, -46, 24, -6, 11, 29, -39, -22, 8, 14, 50, -23, -12, -33, -95,-106, 2; /M: SY='Q'; M= 34, 22, 25, 20,-109, -95, 27, -60, 9, -76, -97, -8, 21, 34, -12, 21, -19, -38,-114, -99; /M: SY='K'; M= -92, -32, 16, -8, -52, -45, 47, -54, 55, -26, -93, -12, 13, -21, 20, 23, 1, -14,-113, -94; /I: I=-19; MI=0; MD=-47; IM=0; DM=-47; /M: SY='P'; M= -26,-121, -18, 1,-122, -62, -4, -60, -16,-120,-110, -10, 69, -7, -3, 26, -9,-114,-124,-114; D=-19; /I: I=-19; DM=-47; /M: SY='P'; M= -21, 16, 3, 35,-111, -53, -2, -36, -22, -23, -99, 6, 74, -17, -50, -46, -21, -28,-119,-107; D=-19; /I: I=-19; DM=-47; /M: SY='R'; M= -31,-107, 31, -82,-104,-100, -7, -67, 41, -22, 10, -1, 18, 21, 49, 1, 15, -33,-111, -37; /M: SY='T'; M= -34, 6, -21, -93, -47,-100, 9, -29, -38, -94, -91, -82, -41, -93, -49, 2, 101, 1,-118, -96; /M: SY='Y'; M= -48,-106,-106,-102, 35, -45, -24, 39, -35, -28, -19, -99, -44, -15, -7, -33, 19, 27, 25, 69; /M: SY='C'; M= -42, 85, -97, -1, -22,-107, 7, -4, 63, 7, -87, -49,-105, -11, -41, -62, -92, -4, 14, -7; /M: SY='Q'; M= -31, -32, -26, 52,-101, -61, -93, 27, -30, -25, -89, -39, -97, 53, -34, 18, 41, -11,-112, -97; /M: SY='Q'; M= -91,-109, 22, 34,-113, -97, 1,-111, 31,-109, -99, 33, -44, 64, 39, 33, -44,-107,-113, -98; /M: SY='H'; M=-100,-112, -46, -89, -95,-105, 135, 16, -92, -35, -83, -12, -24, -11, -38, -93, -97, -16, 3, -27; /M: SY='F'; M=-102,-104,-117,-110, 98,-116,-101, -4,-107, 45, -19,-110, -26, -25, -45,-106, -97, -17, -85, -65; /M: SY='F'; M= -99,-103,-116,-110, 70,-117,-104, 45, -42, 53, -70,-110,-113,-108,-107,-105, -31, 15, -94, -29; /M: SY='T'; M= 36, -28,-102, -35, -42, -66, -9, 12, -98, 24, -80, -96,-103, -37,-102, 10, 39, 37,-110, -34; /M: SY='L'; M= -30,-101,-112,-107, -38, -45,-104, 0,-107, 72, -68,-108, -29,-103,-107, -99, 12, 37,-107, -89; /M: SY='S'; M= 26, 14, -44, -52, 21, -61, -96, -34, -52, -6, -90, -88,-102, -90, -98, 76, -17, -6,-104, 2; /I: I=-6; MD=-16; /M: SY='E'; M= -53,-125, -28, 38,-120,-121,-117, 10,-108, -74,-111,-110,-118,-104, -35, 32, -13, 2, 2,-117; D=-6; /I: I=-6; MD=-16; /M: SY='W'; M= -71, -35, 15, -1, -49,-129,-120,-138, -5,-137,-130, -14, 21, 24, -40, -59, -68,-137, 42,-124; D=-6; /I: I=-6; MI=0; MD=-16; IM=0; DM=-16; /M: SY='D'; M= -33,-132, 30, -11,-132, -48,-117,-129, -54, -62,-125, -37, -26, 10, -35, 16, -17, -73, 21,-123; D=-6; /I: I=-6; DM=-16; /M: SY='H'; M= 9,-107, 20, 8, -61, -2, 59, -61, 0, -43, -94, 5, 2, 48, -17, 11, -19,-101,-107, 19; /M: SY='P'; M= -9,-108, 38, 33,-109, -11, 19, -66, -37, -76, -98, 39, 50, 30, -8, 13, -49, -41,-113, -35; /M: SY='E'; M= -47,-109, 28, 57, -12, 3, 1, -51, -19,-105, -98, 26, -23, 41, 42, -16, -22,-105,-110, -96; /M: SY='V'; M= -30, -1,-105, -97, -89, -32,-103, 25, 25, 26, -76, -98,-105, 0, -10, -39, 7, 60,-110, -93; /M: SY='L'; M= -23, -22,-113,-107, 43,-113,-104, 35,-107, 62, -18,-109, 23,-105,-107,-102, -36, 13,-100, -82; /M: SY='V'; M= -14, -5,-113,-109, 19, -65,-110, 57,-106, -10, 22,-106,-108,-105,-108, -38, -45, 72,-107, -87; /M: SY='F'; M= 0, 8,-107,-105, 76,-106, -93, -29,-102, 33, 0, -29,-110,-101,-102, -4, 5, -51, -85, 59; /M: SY='A'; M= 78, -98, -97, -96,-110, 64,-101,-105, -96,-106, -98, -87, -98, -92,-102, 12, -87, -94,-107,-105; /M: SY='I'; M= -96,-103,-117,-111, -21,-118,-106, 70,-109, 64, 37,-111,-110,-104,-108,-106, -92, 9,-104, -85; /M: SY='E'; M= -90, -1, -64, 112,-114,-106, -86,-115, -74,-108,-104, -88, -88, -34, -84, -7, -90,-107,-112,-105; /M: SY='V'; M= 44, 4,-109,-104, -87,-104,-109, 47,-103, 16, -75,-103,-106,-102,-106, -90, 1, 61,-111, -94; /M: SY='Y'; M= -97, -25,-103,-102, 43,-107, 43, -7, -99, 26, -78, -47,-111, -37, -98, 11, -34, -44, -79, 99; /M: SY='V'; M= -91, -29,-105, 9, -41,-115,-106, 47, -40, 31, -73,-104,-107, -38, -24, -98, -11, 67,-110, -91; /M: SY='Y'; M=-103,-112,-103,-106, 31,-110, -71, -87, -98, -84, -81,-103,-115, -94, -95, -97, -35, -92, -60, 134; /I: I=-19; MD=-47; /M: SY='T'; M= -51,-104,-103, -56, -2,-110, -4, 10,-101, 18, -85, -43,-105,-101,-106, -23, 81, -15,-111, 12; D=-19; /I: I=-19; MD=-47; /M: SY='T'; M=-107, -35,-114,-113,-117,-122,-118, -17,-111, -30, -12, -54,-118, 20,-117, -2, 71, -31,-136,-116; D=-19; /I: I=-19; MI=0; MD=-47; IM=0; DM=-47; /M: SY='F'; M=-119,-130, -22, -11, 23, -70, -28, 16, -34, -11,-106, -3, -60,-115, -60, -19, -53,-106,-119, 14; D=-19; /I: I=-19; DM=-47; /M: SY='P'; M=-106,-125, 7, 9,-126, -41, -5,-119, 10, -81,-114, 11, 69, -18, -51, 8,-101, -53,-128,-117; D=-19; /I: I=-19; DM=-47; /M: SY='T'; M= -7, -34, 29, 28, -57, -23,-104, -69, 0, -34,-107, -44, -22, -45,-101, 15, 41,-106,-124,-110; D=-19; /I: I=-19; DM=-47; /M: SY='H'; M= -64, -26, 24, -27,-109, -54, 58,-104, 15, -52, -36, -17, -11, 15, 9, 14, 52, -34,-121, -97; D=-19; /I: I=-19; DM=-47; /M: SY='S'; M= 2,-102, -6, -8, -97, 12, 31, 2, -15, -47, -92, 1, -47, -86, -12, 48, 29, -15,-108, 17; /M: SY='E'; M= 1, 18, 5, 45,-101, -57, -23, -53, -12, 10, -91, -39, -7, 6, -11, 41, 17, -35,-112, -98; /M: SY='R'; M= 24,-102, -94, -88, -47, -59, 5, -95, -10, -7, -89, -39,-100, 13, 64, 26, 49, -35,-110, -94; /M: SY='T'; M= -91,-100,-103,-102, -40,-109, 1, 46,-100, 34, -28, -29,-103, -99,-103, -36, 67, 25,-105, 24; /M: SY='I'; M= -96,-103,-117,-111, 26,-119,-108, 68,-109, 57, -66,-111,-111,-106,-109,-105, -91, 36,-102, -82; /M: SY='F'; M=-105,-106,-109,-110, 104,-111, -84, -84,-104, -77, -82, -8,-116,-106,-101,-101, -97, -89, -68, 97; /M: SY='V'; M= -88,-101,-116,-111, -83,-118,-116, 68,-108, -40, 0,-109,-109,-108,-109,-100, -85, 88,-114, -91; /M: SY='S'; M= -23, -27, -87, -32,-106, -40, -91,-105, -89,-108,-102, -77, -95, -81, -93, 108, -27, -97,-114, -98; /M: SY='K'; M= -94,-108, -86, -73,-110,-101, -90,-110, 114,-109, -97, -79, -94, -71, -56, -88, -33,-106,-104, -97; /M: SY='A'; M= 74, 40,-106,-100, -94, -95,-106, -6,-100, 6, -81,-101,-105, -98,-103, -84, -85, 53,-111, -98; /M: SY='D'; M= -99,-112, 122, -63,-119, -96, -85,-118, -37,-116,-115, -67, -98, -85, -94, -87, -89,-114,-134,-102; /M: SY='T'; M= -78, -94, -88, -90,-102, -89, -95, -97, -89,-101, -96, -77, -93, -86, -95, 83, 92, -89,-117, -97; /M: SY='T'; M= -53, -94, -87, -91,-101, -93, -95, -93, -37, -98, -94, 25, -93, -89, -94, 49, 102, -36,-118, -98; /M: SY='G'; M= -81,-108, -96,-107,-113, 104,-102, -54,-101,-116,-106, -82, -27, -98,-108, -28, -98,-113,-106,-109; /M: SY='Y'; M= -99, 7,-104,-100, 52,-109, 35, -33, -98, 23, -78,-100,-112, 27, -96, -27, -42, -88, -76, 102; /I: I=-6; MD=-16; /M: SY='C'; M= 0, 55,-113,-112, -49, 18, -10, -60, -36, -16,-108, -33,-120, -13,-114, 32, -51, -44,-128,-114; D=-6; /I: I=-6; MD=-16; /M: SY='P'; M=-112,-128, 30,-100,-131,-116, -6,-125, 11, -76,-120, -14, 51, -18,-108, 8, 16,-123,-137,-121; D=-6; /I: I=-6; MI=0; MD=-16; IM=0; DM=-16; /M: SY='H'; M= -40, -6,-125, -66,-122,-131, 10, -8, 3, -23,-110,-118,-130, -45, 2, -12, -9, -1,-139,-120; D=-6; /I: I=-6; MI=0; MD=-16; IM=0; DM=-16; /M: SY='L'; M=-123,-133,-136,-129,-109, -72, -39, 7, -18, 23, -22,-130, -59, -32,-125,-126, -19, -7,-131, -1; D=-6; /I: I=-6; DM=-16; /M: SY='K'; M= -56,-137,-114,-110,-137,-126, 31, -71, 39,-136,-124, 25, -35, -15, 20, -38,-117,-134,-141,-123; D=-6; /I: I=-6; DM=-16; /M: SY='L'; M= -60,-135, -28, -7,-117,-139,-127, -23, -71, 20,-106,-128, -26, -24, -13,-125, -53, -1, -3,-121; D=-6; /I: I=-6; DM=-16; /M: SY='P'; M= -37,-137,-120, -31,-131,-129,-121, -24, 34, -43, -39,-118, 41, -47, 3, -38, -63,-121,-135,-126; D=-6; /I: I=-6; DM=-16; /M: SY='K'; M=-118,-134,-119, -41, -58, -40,-120, -48, 33, -28,-117, -51, 4, -40, 10, -16, -13, -63,-134,-123; D=-6; /I: I=-6; DM=-16; /M: SY='S'; M= -73,-130, -66,-119,-127, -3, -34, -69, -25, -29, -14, -56, -26, -20, -20, 24, -23, -14,-139,-124; D=-6; /I: I=-6; DM=-16; /M: SY='T'; M= -41,-129, 8, -40, -35, -8, 13,-124, -31, -80, -37, -25, -22, -54, -54, -23, 24, -68,-132, -6; D=-6; /I: I=-6; DM=-16; /M: SY='P'; M=-116,-134, -31, 1,-129,-123, 12, -73, -19, -89, -33,-112, 65, -18, -6, -19, -3,-124,-133, -47; D=-6; /I: I=-6; DM=-16; /M: SY='K'; M= -34,-130, -19, -58,-124, -17, 7,-115, 7, -39,-115, -17, -51, -9, -62, -31, -18, 2,-136, -25; D=-6; /I: I=-6; DM=-16; /M: SY='K'; M= -7, -1, -8, -7, 0, -82,-119, -40, 12, -81,-119, -26, -13,-113,-114, -25, -64, -37,-128, -12; D=-6; /I: I=-6; MI=0; MD=-16; IM=0; DM=-16; /M: SY='S'; M= -26, -36, -22, -8,-129, -20, -24, -73, 7,-127,-119, 2, 7,-105, -33, 22, 3, -54,-135,-122; D=-6; /I: I=-6; DM=-16; /M: SY='D'; M= -68,-126, 18, -11,-122, -14,-108,-123, 12, -43,-115, -29, -9, 6, -6, 5, -4,-121,-127, -6; D=-6; /I: I=-6; MI=0; MD=-16; IM=0; DM=-16; /M: SY='H'; M= -6,-120, -16, -32,-106, -24, 26, -29, 12, 12, -13,-106, 1, -48, -57, -22, -59, -26,-120, 2; D=-6; /I: I=-6; DM=-16; /M: SY='P'; M= -29,-116, -49, -54, -62, -18,-105, 32, -9, -64, -37, 14, 48, -36, -22, 4, 7, -41, 10, -16; D=-6; /I: I=-6; DM=-16; /M: SY='S'; M= -13, -98, -38, -18,-102, -35, -33, -34, -16, -41, -95, -9, -96, -20, -7, 83, 40, -59,-112, -36; /M: SY='P'; M= 5, -3, -95, -5, -44, -46, -98, -15, 19, -17, -93, -56, 93, -36, -23, -3, -22, -38,-109,-102; /M: SY='T'; M= 7, -2, -47, -17, -26, -39, -34, 34, -9, -4, -22, -18, -23, -90, -15, 28, 51, -49,-106, 1; /M: SY='T'; M= 5,-101, -91, -48, -56, -17, -92, -17, 7, -66, -92, 5, -18, 7, 42, 37, 57, -25,-110, -36; /I: I=-22; MD=-55; /M: SY='T'; M= -23,-104, -44, 10,-101,-100, 12, -2, -20, -33, -92, 25, -6, 3, -16, 31, 51, 2,-115, -29; D=-22; /I: I=-22; MI=0; MD=-55; IM=0; DM=-55; /M: SY='T'; M= 14,-107,-110, -55, -27, -30,-110, 6, -22, 26, -85,-105, 3,-105,-107, -58, 34, 29,-114, -38; D=-22; /I: I=-22; DM=-55; /M: SY='T'; M= 14, -12,-103, -33, -47, -38,-105, 22, -16, -31, -90, -96, -49, -28, -15, 8, 54, 17,-115, -36; D=-22; /I: I=-22; DM=-55; /M: SY='R'; M= 3, -24, 19, -21, -24, -27, -2, -58, -3, -65, -98, 15, -40, -87, 39, 32, 27, -6,-116, -98; D=-22; /I: I=-22; DM=-55; /M: SY='A'; M= 59, 1,-100, -97, 29, -27, -99, -91, -53, -9, -89, -92, -49, -95, -49, 23, 40, -34, -3, 5; D=-22; /I: I=-22; DM=-55; /M: SY='L'; M= -97,-101,-111,-107, 57, -57, -22, 18,-104, 66, -69,-104,-110,-103, -50, -99, 32, -26, -96, -17; /M: SY='R'; M= -28,-104, -97, -9, -48, -67, -96, 28, 33, -2, 11, -18, -43, -22, 40, 10, -15, 33,-109, -93; /M: SY='S'; M= 20,-102, -6, -32, -13, -45, 25, 31, -21, -42, -87, -27,-101, -22, 7, 44, 7, -5, -16, 12; /M: SY='L'; M= -22,-104,-110,-105, 47,-111, 34, 18, -53, 57, -18,-105,-111, -99, -39, -56, -94, -15, -13, 53; /I: I=-45; MD=-115; /M: SY='I'; M= 22, -22,-107,-103, 4,-104, -10, 45, -36, 33, -9, -48,-107, -98,-102, 17, -87, 23,-101, 22; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='D'; M= 2, -22, 31, 26, -50, -99, 24, -92, 2, -21, -91, 22,-100, 14, 29, 5, -3, 22,-114, -95; /M: SY='R'; M= -17,-107, 14, -5, -49, -25, 29, -56, 8, -76, -94, -40,-100, 32, 61, 1, 23, -25, 36, 10; /M: SY='H'; M= -8, -32, -99, -9, 38,-105, 54, -10, -64, 37, -79, -49, 35, -14, -58, -31, 3, -23, -98, 27; /M: SY='R'; M= -17,-108, -7, -14, -9, -62, -88, -16, 20, -11, -90, -21, -3, 55, 64, -2, -17, -95,-104, -12; /M: SY='Q'; M= 6,-104, -15, -14, -48, -27, 10, -99, 15, -12, -91, 10, -40, 47, 39, 16, 34, -56,-109, -34; /I: I=-2; MD=-4; /M: SY='R'; M= -20,-124, 3, -30,-124, -12, -32,-123, -13, -44,-112, -53, -46, 15, 55, 19,-105,-119,-126,-113; D=-2; /I: I=-2; MI=0; MD=-4; IM=0; DM=-4; /M: SY='P'; M= -8, -26, -22, -39, -48, -44, -34,-126, -42,-129,-123, 9, 13, 6, -57, -20, -11, -42, -3, -43; D=-2; /I: I=-2; DM=-4; /M: SY='C'; M= -36, 35,-122,-119, -37, -34, -27,-112, -53, -1,-110, -25, 26, -19,-122, -9, 0, -29,-132, -49; D=-2; /I: I=-2; DM=-4; /M: SY='P'; M= -39,-124, -20, -28,-117, -70, -3, -13, -39, -54, -6, -27, 63, -21, -36, -1, -21, -10,-126, -39; D=-2; /I: I=-2; DM=-4; /M: SY='P'; M= -23, 11, -32, -8, -47, -7, 26,-100, 16, -21, -94, 7, 63, 35, 0, -53, 18, -29,-113, -99; D=-2; /I: I=-2; DM=-4; /M: SY='N'; M= 18, -19, -8, -6,-106, 23, -4, -11, -25, -66, -27, 52, 17, 11, -28, 7, -88, 2,-115,-101; D=-2; /I: I=-2; DM=-4; /M: SY='I'; M= -28, -30, -26, 2, -33,-106, -25, 39, -7, -18, -86, -27, 21, 36, 28, -2, -16, 3, 18, -43; D=-2; /I: I=-2; DM=-4; /M: SY='H'; M= -55,-108, -90, -16,-102,-102, 65, -10, 13, -42, -91, 20, -42, 37, 51, 8, 22, -15,-112, -20; D=-2; /I: I=-2; DM=-4; /M: SY='T'; M= -42, 16,-106,-104, -31,-109, -25, 23,-102, 33, -22, -98,-106,-101,-105, 7, 57, 45,-113, -92; D=-2; /I: I=-2; DM=-4; /M: SY='W'; M= -35,-108, -98, -49, -97,-102, 16, -34, 41, -67, -93, -27,-103, -35, 41, 28, 14, 24, 96, -88; D=-2; /I: I=-2; DM=-4; /M: SY='I'; M= -93,-104,-118,-113, -82,-120,-114, 69,-110, 35, -69,-112,-111,-108,-111,-104, -89, 69,-111, -91; D=-2; /I: I=-2; DM=-4; /M: SY='H'; M= -23, 87, -95, -93, 9, -97, 90,-105, -94,-101, -95, -27, -28, 13, -96, 54, 7, -59,-116, -33; D=-2; /I: I=-2; DM=-4; /M: SY='L'; M= -58,-103,-117,-110, -36,-118,-105, 32,-110, 79, -18,-114,-114,-105,-109,-107, -49, 11,-106, -87; D=-2; /I: I=-2; DM=-4; /M: SY='F'; M=-108,-104,-120,-115, 120,-116,-101, -81,-110, -5, -82,-110,-119,-120, -50,-107,-100, -86, -76, -54; D=-2; /I: I=-2; DM=-4; /M: SY='A'; M= 84, -94, -97, -93,-106, -87,-102, -96, -94, -99, -94, -89, -97, -93,-100, -25, 69, -85,-112,-102; D=-2; /I: I=-2; DM=-4; /M: SY='R'; M= -59,-115, -97, -85,-107,-110, -87, -20, 5, -55, -94, -90,-108, -75, 113, -94, -98,-103,-108, -95; D=-2; /I: I=-2; DM=-4; /M: SY='A'; M= 71, -99, -95, -37,-110, -86, -99,-102, -92,-106, -98, -90, 51, -89, -47, 60, -24, -93,-112,-104; D=-2; /I: I=-2; DM=-4; /M: SY='Q'; M= 32,-111, -85, 35,-118, -97, -24,-108, -40,-104, -94, -86, -98, 113, -79, -19, -92,-104,-108, -97; D=-2; /I: I=-2; DM=-4; /M: SY='P'; M= -21,-109, 31, -18,-114, 31, -93,-111, -28,-114,-104, 36, 65, -88, 17, 29, -22,-108,-115,-106; D=-2; /I: I=-2; DM=-4; /M: SY='Q'; M= 10,-114, -49, -26, -60, -99, -5,-106, -76, -55, -90, -85,-100, 124, -36, -82, -94,-106,-106, -94; D=-2; /I: I=-2; DM=-4; /M: SY='Y'; M=-105,-116,-104,-107, -52,-111, -71, -90, -99, -87, -83,-106,-116, -94, -96,-100, -99, -95, 26, 137; D=-2; /I: I=-2; DM=-4; /M: SY='L'; M=-100,-103,-118,-110, -74,-119,-102, -4,-111, 90, 4,-116,-116,-104,-108,-110, -96, -72, 22, -86; D=-2; /I: I=-2; DM=-4; /M: SY='F'; M=-108,-105,-119,-115, 121,-116,-100, -36, -39, -74, -84,-109,-118,-119,-106,-107,-100, -87, -74, -2; D=-2; /I: I=-2; DM=-4; /M: SY='P'; M= -2,-118, -99, -89,-116, -98,-102, -62, -94,-113,-102, -49, 119, -97, -33, -11, -21,-106,-113,-113; D=-2; /I: I=-2; DM=-4; /M: SY='N'; M= -30,-105, 14, 18, -47, 50, -15,-109, 5, -72,-102, 74,-101, -86, -92, 5, -33, -43,-116,-103; D=-2; /I: I=-2; DM=-4; /M: SY='S'; M= -75, -97, -89, -90, -28, -83, -92,-106, -90,-109,-103, -78, -97, -82, -95, 110, -27, -99,-114, -97; D=-2; /I: I=-2; DM=-4; /M: SY='S'; M= 41,-101, -27, -6,-105, -33, -25, 2, -20, -99, -95, -41, 11, -88, -96, 69, -80, 6,-113,-100; D=-2; /I: I=-2; DM=-4; /M: SY='E'; M= -34,-111, 32, 76,-112,-103, -2,-109, 54, -48,-100, -7, -95, 11, -27, -88, -41, -47,-114,-101; D=-2; /I: I=-2; DM=-4; /M: SY='N'; M= -96,-103, -48, -93, -26, -25, 2, -38, -85,-108, -99, 114,-107, -23, -92, -54, -84, -30, 52, -3; D=-2; /I: I=-2; DM=-4; /M: SY='P'; M= -9,-110, -92, 15,-110, 25, 2, -43, 37, -57, -22, -90, 70, -87, -44, 25, -27, -45,-111,-103; D=-2; /I: I=-2; MI=0; MD=-4; IM=0; DM=-4; /M: SY='G'; M= -62,-108, -10, -5,-109, 53, 25,-112, 40, -51,-100, 23,-100, -35, 23, 26, -53,-108,-111, -39; D=-2; /I: I=-2; DM=-4; /M: SY='K'; M= -95,-110, -89, -75,-111,-103, -92,-109, 112,-110, -98, -81, -96, -73, -57, -90, -90, -43,-106, -98; D=-2; /I: I=-2; DM=-4; /M: SY='H'; M= -99,-113, -89, -85,-103, -44, 133,-115, 27,-103, -90, -79,-103, -79, 36, -43, -43, -56,-125, -78; D=-2; /I: I=-2; DM=-4; /M: SY='V'; M= -90, -1,-110,-105, -42,-114,-112, 42, -24, -39, -78, -11, 21, -40, -56, -99, -87, 83,-115, -95; D=-2; /I: I=-2; DM=-4; /M: SY='L'; M= -60, -20,-115,-108, -77, -31,-102, 10,-107, 84, -22,-112,-115, -41, -32,-107, -96, -50,-105, -88; D=-2; /I: I=-2; DM=-4; /M: SY='D'; M= -42,-104, 70, -7,-112, 5, -89,-111, -88,-113,-107, 48, -50, -85, -95, 63, 8,-106,-122,-103; D=-2; /I: I=-2; DM=-4; /M: SY='D'; M= -93,-113, 101, -76,-119, 64, -92,-121, -93,-118,-113, -73,-101, -92,-101, -86, -94,-117,-123,-106; D=-2; /I: I=-2; DM=-4; /M: SY='R'; M= 11,-108, 17, 18,-108, -11, -91, -37, -30, -61, -25, -3, -42, 32, 59, -11, 11, -16,-113, -99; D=-2; /I: I=-2; DM=-4; /M: SY='Q'; M= -5,-110, -23, -8,-115, 58, -29,-110, 14,-108, -99, -32,-100, 80, -16, -30, -31, -41,-109,-101; D=-2; /I: I=-2; DM=-4; /M: SY='L'; M=-100,-102,-117,-110, -74, -47,-102, -66,-111, 93, -62,-116,-117,-104,-108,-110, -96, -73,-104, -87; D=-2; /I: I=-2; DM=-4; /M: SY='C'; M= -95, 61,-116,-111, -83,-118,-110, 56,-109, 50, -29,-110,-113, -39,-110,-104, -46, 47,-112, -92; D=-2; /I: I=-2; DM=-4; /M: SY='K'; M= -12,-109, -49, -45,-110, -43, -22,-109, 84, -80, -98, 5,-100, 5, 52, -10, -90, -61,-109, -98; D=-2; /I: I=-2; DM=-4; /M: SY='W'; M=-108,-133,-136,-113, -74,-107,-136,-104,-105,-103,-106,-129,-112,-105,-109,-115,-120, -46, 179, -61; D=-2; /I: I=-2; DM=-4; /M: SY='W'; M=-109,-134,-135,-112, -74,-107,-134,-107,-103,-104,-107,-128,-112,-104, -33,-115,-121,-121, 179, -61; D=-2; /I: I=-2; DM=-4; /M: SY='C'; M= -12, 77,-106, -98, -92, -51, 10, 32, 44, 24, 25, -98,-108, -94, 3, -97, -93, -10, 17, -93; D=-2; /I: I=-2; DM=-4; /M: SY='R'; M= 7,-107, -5, -84, -16, -15, 4,-109, 48,-107, -98, -39, -22, -12, 64, 31, -17,-103,-109, -96; D=-2; /I: I=-2; DM=-4; /M: SY='V'; M= -23, 36,-113,-109, -86,-114,-112, 54,-107, 2, -75,-106,-109,-107,-109, -60, 13, 70,-112, -15; D=-2; /I: I=-2; DM=-4; /M: SY='L'; M= -65,-104,-118,-111, 31,-118,-104, 44,-110, 66, 38,-113,-114,-106,-109,-107, -94, 11,-100, -28; D=-2; /I: I=-2; DM=-4; /M: SY='D'; M= -42,-108, 92, 20,-114, -13, -22,-112, -88, -54,-107, 26, -99, -85, -95, 37, -31,-108,-125,-102; D=-2; /I: I=-2; DM=-4; /M: SY='P'; M= -63,-113, 58, -3,-114, -14, -91,-110, 36, -74, -26, 4, 67, 2, 13, -6, -53,-109,-115,-104; D=-2; /I: I=-2; DM=-4; /M: SY='V'; M= 13,-102,-111,-107, -86, -45,-109, 48,-106, 38, -74, -55, -29,-103,-108, -20, -27, 54,-111, -93; D=-2; /I: I=-2; DM=-4; /M: SY='L'; M= 16, -25,-107,-103, -13,-106,-103, 21, -56, 41, 13, -43,-107, -98, -12, 4, 19, 27, -8, -90; D=-2; /I: I=-2; DM=-4; /M: SY='R'; M= -38, 11, -3, -38, -99, -18, -33, -1, -5, -13, -17, -49, -8, -3, 41, 29, -17, 32, -16, -97; D=-2; /I: I=-2; DM=-4; /M: SY='E'; M= -3,-109, 48, 52,-110, -27, 24,-109, -17, -52,-100, 3, -29, 31, -21, 12, 7,-105,-116, -37; D=-2; /I: I=-2; DM=-4; /M: SY='W'; M= -47, 36, -21, -43, 9, -28, 38, -5, -37, -24, -89, -51, -49, 18, -27, -2, 11, 9, 56, 48; D=-2; /I: I=-2; DM=-4; /M: SY='F'; M= 13, -23, -16, 32, 45, -4, 10,-105, -36, -61,-100, -97, -58, -42, 21, -33, -1, -59, -4, -3; D=-2; /I: I=-2; DM=-4; /M: SY='D'; M= 3, -1, 45, 8, -51,-104,-100, -68, 0, -65,-108, -6, 31, -17, -8, 20, -7,-109,-123,-109; D=-2; /I: I=-2; DM=-4; /M: SY='S'; M= -7,-116, 10, 25,-120, -44, -4,-115, -60, -55,-109, 22, 3, 9, -29, 28, 8, -60,-127,-111; D=-2; /I: I=-2; DM=-4; /M: SY='N'; M= -8,-118, -12, 0,-121, 15,-105, -37, -5,-119,-112, 27, -31, 1, -36, 15, 7, -74,-126, -58; D=-2; /I: I=-2; DM=-4; /M: SY='H'; M= -19,-128, -20, -13,-128, -38, 34,-121, -12, -45, -42, -11, -20, 31, -58, -6, -15, -46,-136,-117; D=-2; /I: I=-2; MI=0; MD=-4; IM=0; DM=-4; /M: SY='W'; M= 21,-104, -47,-100, -44, -67, -4, -10,-100, -23, -20, -96, 22, -99,-104, 4, 55, 32, 65, -16; D=-2; /I: I=-2; DM=-4; /M: SY='K'; M= -93, -26, 4, 17,-110, -61, 9, -61, 60,-104, -25, -41, -98, 51, 36, -20, 31, -44,-112, -97; D=-2; /I: I=-2; DM=-4; /M: SY='A'; M= 65, 49,-102, -97, -47, 26, -2, -96, -12, 3, 22, -94,-104, -37, -5, -33, -91, -91,-109, -99; D=-2; /I: I=-2; DM=-4; /M: SY='W'; M= -50, -30,-103, -97, 54, -59, 26, -95, 41, -47, -4, -97,-108, -92, -3, -47, -10, -97, 84, 81; D=-2; /I: I=-2; DM=-4; /M: SY='Y'; M= -61,-107,-113,-109, -32, -46, -92, -1,-106, 58, 12,-111,-114,-101,-104,-104, -97, 3, 61, 84; D=-2; /I: I=-2; DM=-4; /M: SY='I'; M= -42,-105, -50,-100, 8,-112, -28, 40, -95, 38, -75, -26,-109, 19, 23, -45, -5, 28,-104, 0; D=-2; /I: I=-2; DM=-4; /M: SY='I'; M= -92,-104,-117,-112, -83,-119,-114, 71,-110, 26, -70,-110,-111,-108,-111, -38, -88, 69,-112, -91; D=-2; /I: I=-2; DM=-4; /M: SY='P'; M= -45,-124,-100, -89,-119,-101,-103,-107, -96,-117,-103,-106, 128, -99,-108, -96, -92,-111,-112,-116; D=-2; /I: I=-2; DM=-4; /M: SY='G'; M= -58,-109, -97,-109,-116, 104,-104,-123,-103,-119,-108, -83,-101,-100,-110, -42,-100,-116,-107,-111; D=-2; /I: I=-2; DM=-4; /M: SY='Y'; M= -2, 40, -94, 42, 37,-105, -23, -23, -95, 7, -23, -98,-106, -46, -98, 20, -52, -90, -89, 74; D=-2; /I: I=-2; DM=-4; /M: SY='D'; M= -47,-108, 87, 39,-115, -95, -88,-113, -86,-113,-108, 11, -3, -22, -93, 45, -12,-108,-124,-103; D=-2; /I: I=-2; DM=-4; /M: SY='S'; M= -42,-108, 17, 16, -49, -44, -90,-107, 31,-108,-100, 20, 34, 20, 28, 35, 14, -60,-112, -42; D=-2; /I: I=-2; DM=-4; /M: SY='Q'; M= 0,-109, -99, 13, -4, -33, 21, 15, -24, 19, -32, -55,-107, 22, -3, 0, -30, -18,-104, 22; D=-2; /I: I=-2; MI=0; MD=-4; IM=0; DM=-4; /M: SY='E'; M= -27,-111, -1, 81, -49,-105, -92, -64, -36, -62,-101, -16, -98, -3, 12, 12, -2, -16,-116,-103; D=-2; /I: I=-2; DM=-4; /M: SY='T'; M= 24, -98, -99, -97, -49, -97,-100, 33, -60, -9, 35, -40, -99, -93,-100, 48, 59, -1,-111, -94; D=-2; /I: I=-2; DM=-4; /M: SY='R'; M= -15,-107, -92, 5, -97,-104, 45, -52, 19, 8, -26, -36,-102, -2, 77, -23, -7, -15,-108, -19; D=-2; /I: I=-2; DM=-4; /M: SY='S'; M= 25,-103, -46, -45,-106, -14, 30,-103, 34, -60, -95, 1, 14, -11, 39, 41, 12, -46,-111, -97; D=-2; /I: I=-2; DM=-4; /M: SY='Y'; M= -99,-106,-108,-106, 74, -56, -6, 5, -57, 13, 13,-102,-111,-100, -15, -34, -5, -33, 24, 82; D=-2; /I: I=-2; DM=-4; /M: SY='L'; M= -54,-102,-112, -46, 51,-115, -4, 44,-106, 61, -29,-107,-110,-104,-106,-102, -6, 13, -99, -78; D=-2; /I: I=-2; DM=-4; /M: SY='P'; M= -64,-114, -29, -14,-106, -20, -26, -47, 4, -52, -97, -25, 101, -40, 28, -3, -46, -69,-107, -3; D=-2; /I: I=-2; DM=-4; /M: SY='P'; M= -11,-105, 3, -30,-103, 13, -92, -15, 16, -4, -93, 35, 41, -34, 26, 35, -49, -56,-111, -99; D=-2; /I: I=-2; DM=-4; /M: SY='S'; M= 17, -28, -27, -28, -45, -28, 14, -89, -89, 0, -35, 0, 32, -19, 11, 35, 30, 10,-111, -35; D=-2; /I: I=-2; DM=-4; /M: SY='S'; M= 5,-104, -14, -7, 0, -37, -24, -59, 24, -39, -94, 22, 35, 22, 16, 39, 2, -44,-108, -95; D=-2; /I: I=-2; DM=-4; /M: SY='Y'; M= -1, -31, 13, -1, 2, -60, -3,-109, -2, -52,-102, 24, -18, -3, 14, 14, -10,-106, 8, 27; D=-2; /I: I=-2; DM=-4; /M: SY='S'; M= -7,-114, 9, -55, -33, -16,-103,-108, -32, -28, -29, -45, 44, 13, -42, 47, -3, -61,-120,-107; D=-2; /I: I=-2; DM=-4; /M: SY='D'; M= -48,-128, 30, -56,-126, -41, -30, -35, -24, -40,-116, -34, -22, 15,-114, 18, -21, -29, -6,-119; D=-2; /I: I=-2; MI=0; MD=-4; IM=0; DM=-4; /M: SY='P'; M= -7,-128,-122,-121,-122, -55, -29, -19, -76, -12,-110, -2, 19,-118, -23, -15, 1, -13,-138,-123; D=-2; /I: I=-2; DM=-4; /M: SY='N'; M= 2,-109, 8, -90, -56, -11, -5, -62, -3, -29, -99, 73, -10, 15, 29, -4, -90, -64,-119,-102; D=-2; /I: I=-2; DM=-4; /M: SY='W'; M=-107,-132, -34,-110, -73,-105,-133,-105,-103,-103,-106,-125,-110,-103,-107,-113,-119,-120, 181, -59; D=-2; /I: I=-2; DM=-4; /M: SY='T'; M= -46,-102, -92, 13, -11, -66, -11, 31, 7, -22, -85, -23, -99, 14, 2, 25, 52, 11,-108, -34; D=-2; /I: I=-2; DM=-4; /M: SY='Y'; M= -49, -23, -26, -53, -46,-107, 28, 23, -96, -17, -21, 14, -28, 11, -97, -51, -91, 33, 24, 93; D=-2; /I: I=-2; DM=-4; /M: SY='G'; M= -80,-105, -44,-102,-111, 95, -99,-117, -98,-114,-105, -41, -99, -95,-105, 32, -6,-110,-107, -43; D=-2; /I: I=-2; DM=-4; /M: SY='H'; M= -99,-111, 50, -83, -95,-100, 123,-111, -90,-103, -92, 13, -13, -84, -90, -18, 5,-110,-115, 45; D=-2; /I: I=-2; DM=-4; /M: SY='P'; M= -40,-115,-104, -96,-102,-105,-106, 56,-100, -91, -32,-104, 105,-101,-109, -23, -29, -2,-111,-104; D=-2; /I: I=-2; DM=-4; /M: SY='Y'; M=-104,-107,-111,-109, 83,-114, 15, -47,-104, 28, -29,-107,-116,-103, -54,-103, -98, -38, -75, 92; D=-2; /I: I=-2; DM=-4; /M: SY='S'; M= -38,-110, 25, 20,-111, 4, 28, -51, -21, -40,-103, -7,-104, -35, -18, 52, -4, -46,-120, -46; D=-2; /I: I=-2; MI=0; MD=-4; IM=0; DM=-4; /M: SY='Q'; M= -4,-113, 6, 16,-111, 6, -98, -60, -20, -14,-100, 7, -43, 48, -24, 17, -13, -47, 21,-104; D=-2; /I: I=-2; DM=-4; /M: SY='I'; M= -29,-112, 8, -12,-103,-106, 14, 33, -18, -3, -30, 24, 31, -38, -32, 16, -6, -41,-119,-101; D=-2; /I: I=-2; DM=-4; /M: SY='S'; M= -14, 23, 34, -6,-106, 25, -93,-102, -32, -23, -97, 2, 23, 12, -94, 55, 4, -40,-114,-101; D=-2; /I: I=-2; DM=-4; /M: SY='H'; M= -11,-103, 33, 3, -40, -40, 51, -19, -22, -66, -9, 48, -12, -47, -20, 50, -4, -30,-116, -94; D=-2; /I: I=-2; DM=-4; /M: SY='S'; M= 1,-105, 45, -23,-101, 19, 6, -59, -17, -68, -99, 2, 40, -86, -48, 52, -31,-101,-107, 31; D=-2; /I: I=-2; DM=-4; /M: SY='L'; M= -36, 36, -4, -52, 14,-104, -97, 4, 1, 40, -81, -41, 35, -8, -11, 10, 16, -51,-105, -46; D=-2; /I: I=-2; DM=-4; /M: SY='A'; M= 70, -99, -17, -48,-107, -29, -3,-102, -5,-104, -96, -25, 32, -86, -7, 42, -18, -93,-110, -48; D=-2; /I: I=-2; DM=-4; /M: SY='V'; M= 24, 2, 13, -20, -44,-103, -3, 19, -97, 6, -81, -96, 20, -96, -32, -25, -2, 55,-113, -94; D=-2; /I: I=-2; DM=-4; /M: SY='Y'; M= -94, -36, -12, 0, 33, -4, 4, -59, -5, -65, -92, 20, 52, 4, -16, 0, -2, -66, -93, 64; D=-2; /I: I=-2; DM=-4; /M: SY='N'; M= -33, -25, 23, 0,-107, -45, -5,-100, 10, -46, -25, 48, 35, 26, 27, 14, 14, -19,-114, -98; D=-2; /I: I=-2; DM=-4; /M: SY='R'; M=-114, 13, -56,-115,-116, -42, -42, -35,-108, -5, -35, -31, -9, -4, 26, -2, -35, -13, 10, -44; D=-2; /I: I=-2; MI=0; MD=-4; IM=0; DM=-4; /M: SY='I'; M= -95,-107,-117,-114, -80,-120,-113, 101,-109, -1, 33,-108,-107,-106,-112,-104, -89, 22,-106, -88; D=-2; /I: I=-2; DM=-4; /M: SY='P'; M= -48,-123, -98, -87,-117, -99,-101,-105, -94,-115,-102,-105, 130, -98,-107, -94, -90,-110,-111,-115; D=-2; /I: I=-2; DM=-4; /M: SY='H'; M= -30, -25, -98, -93, -89, -28, 65, -34, -36, 38, -28, -91,-105, -28, 58, 19, -7, -19,-107, 4; D=-2; /I: I=-2; DM=-4; /M: SY='F'; M=-106,-103,-117,-113, 116,-114, -95, -78,-109, 12, -79,-109,-117,-115,-106,-105, -98, -84, -73, 40; D=-2; /I: I=-2; DM=-4; /M: SY='P'; M= -95, -7, 21, 12,-116, -98, -97,-107, -91,-114,-103, -40, 118, -92,-102, -4, -89,-110,-113,-111; D=-2; /I: I=-2; DM=-4; /M: SY='D'; M= -99,-113, 123, -62,-120, -96, -85,-118, -86,-116,-115, -67, -98, -86, -95, -87, -89,-115,-135,-102; D=-2; /I: I=-2; DM=-4; /M: SY='D'; M= -99,-113, 123, -62,-120, -96, -85,-118, -86,-116,-115, -67, -98, -86, -95, -87, -89,-115,-135,-102; D=-2; /I: I=-2; DM=-4; /M: SY='P'; M= -15,-121, -98, -87,-117, -98,-101,-105, -94,-115,-101,-104, 128, -98,-107, -93, -90,-109,-111,-114; D=-2; /I: I=-2; DM=-4; /M: SY='K'; M= -94,-108, -87, -73,-110,-102, -90,-108, 113,-108, -97, -80, -95, -72, -56, -89, -89, -42,-104, -97; D=-2; /I: I=-2; DM=-4; /M: SY='A'; M= 62, -22, -92, -92,-105, 40, -97, -99, -92,-102, -95, -82, -95, -88, -97, 57, 46, -56,-109,-100; /M: SY='R'; M= -97,-113, -93, -81,-106,-107, -82,-113, -20,-105, -94, -86,-105, -70, 121, -91, -95,-106,-106, -92; /M: SY='F'; M= -45,-102,-116,-112, 122,-111, -95, -80,-107, -45, -81,-106,-115,-115,-105,-103, -97, -85, 19, 32; /M: SY='L'; M= -95, 0,-113,-105, -38,-114, -98, 26,-101, 79, 58,-109,-111, -98, -1,-104, -92, -11,-102, -84; /M: SY='D'; M= -58, -25, 85, 56,-108, -20, 45, -62, -10, -41, -99, -10, -95, 11, -1, -58, -89,-106,-116, -34; /M: SY='E'; M= -91,-109, 40, 85, -47,-100, 80,-110, -50,-102, -4, -79, -92, 39, -82, 8, -89,-106,-113, -36; /M: SY='L'; M= -96, -99,-112,-106, -73,-115, -99, 20,-106, 88, 18, -38,-112,-100,-105,-104, -39, -20,-102, -84; /M: SY='D'; M= 32, -9, 56, 14, -51, -26, -94, 11, -89, -55, -26, -12, -99, 39, -94, -37, -28, 41,-113, -95; /M: SY='E'; M= -55,-104, 34, 57, -96, -18, -3, -60, -82, -41, -92, -15, -97, -2, 14, 40, -84, 29,-106, 27; /M: SY='E'; M= -60, -20, 46, 87,-111, -28, -86,-108, -78,-105,-101, -25, -90, 25, -86, 18, 29, -66,-114,-100; /M: SY='N'; M= 25, -99, 3, -22, -20, 17, -19, -3, -51, -29, -89, 60, -99, -88, -27, -10, 38, 6,-109, -19; /M: SY='R'; M= -46,-106, 11, 16, -55, -6, 45, -38, -75,-100, 10, -19, 14, -78, 70, 45, -25, -42, -6, -92; /I: I=-5; MD=-12; /M: SY='Y'; M= 15,-110, 8, 27, -97, -31, -5, 19, 7, -28, -94, 9, -43, -44, -29, -27, 4, -64,-107, 37; D=-5; /I: I=-5; MI=0; MD=-12; IM=0; DM=-12; /M: SY='K'; M= -26,-111, -6, 12, -50, -1, 39,-106, 39, -30, -32, -47, 29, 20, -30, 7, 10, -68,-112, -24; D=-5; /I: I=-5; DM=-12; /M: SY='N'; M= -9,-103, 39, 17,-107, 7, -90, -62, 32, -52, -97, 39, -38, -6, -48, 33, 13, -15,-114,-100; D=-5; /I: I=-5; DM=-12; /M: SY='M'; M= -33, -21, -37, -60, -33, 24, 14, 22, 4, -40, 44, -14, -8, -94, -49, -51, 37, 42,-111, -93; D=-5; /I: I=-5; DM=-12; /M: SY='W'; M= -53,-130, -13, -37,-118, -24, -33,-121, -12, -14, -44, 12, 0, -33, 3, -24, -24,-121, 59, -41; D=-5; /I: I=-5; DM=-12; /M: SY='S'; M= -39,-129, -36, -57,-128, -71, -33, -16, 14,-127,-120, -33, 31, -53,-111, 42, -55,-119, 20,-120; D=-5; /I: I=-5; DM=-12; /M: SY='P'; M= -82,-134,-118, -58,-131, 10,-122, -75, 14, -76, -44, -12, 37,-113, -18, -45, 0, -69, 16,-125; D=-5; /I: I=-5; MI=0; MD=-12; IM=0; DM=-12; /M: SY='S'; M= -34,-127, -13, -46,-133, -3, -23,-129,-117, -78,-126, 10,-126,-113,-123, 49, -33, -46,-143,-127; D=-5; /I: I=-5; DM=-12; /M: SY='V'; M=-115,-131, -50, -50,-123,-131,-124, -43, 23,-112, 8,-119, 23, -38, -16, -34,-111, 38,-137,-122; D=-5; /I: I=-5; DM=-12; /M: SY='R'; M=-113,-127,-120,-112,-120, -33,-118, -30, 28, -48, -14,-112, -50, -52, 34,-111, 12, 19,-132,-117; D=-5; /I: I=-5; DM=-12; /M: SY='S'; M= -80, -1, 22, -85,-103, -6, -89,-100, -16,-104, -98, 28, -17, -31, -53, 80, 50, -41,-113, -36; /M: SY='L'; M= -9,-100,-107,-102, -81,-109,-102, 37,-101, 55, 27, -29, 13, -38, -53, -95, 7, 45,-107, -89; /M: SY='D'; M= -23,-105, 77, 54,-110, -95, 15,-108, 29, -60,-100, -37, -93, -5, -50, 28, 5,-103,-116, -97; /M: SY='Q'; M= -15,-107, 13, 66,-110, -98, -25,-105, 6,-102, -6, -14, -93, 81, 9, -14, 25,-101,-109, -96; /M: SY='F'; M= -25,-101,-116,-111, 122,-110, -98, -79,-107, -72, -82,-105,-114,-115,-105, -41, -96, -36, 25, -8; /M: SY='W'; M= -27,-125,-127,-108, -71,-102,-121,-100,-101, -97, 13,-120,-108,-100,-104,-107, -35,-111, 176, 18; /M: SY='E'; M= -46,-107, 12, 97,-106,-102, -86, -4, -45, -65, -3, -6, -90, -11, -85, -17, 5, -27,-111, -99; /M: SY='M'; M= -59,-106, -84, 68, -15,-105, -87, -1, -76, -17, 80, -91, -26, -8, 54, -35, 4, -47,-106, -90; /M: SY='M'; M= -48, -99,-111,-104, -77,-108, -90, -16,-100, 60, 123, -25,-105, -93, -99,-101, -33, -71,-103, -82; /M: SY='Q'; M= 49, -99, -90, -35,-109, 50, -93,-103, -88,-104, -96, -82, -41, 58, -92, 56, -6, -63,-107,-100; /M: SY='F'; M= -16,-104, -99, 27, 95, -18, -4, -21, -97, -79, -4, -24, -28, -97, -98, -95, -94, -26, 1, 62; /M: SY='R'; M= -94,-111, -93, -83,-105, 2, -84,-110, -58, -51, -93, -86,-104, -36, 116, -45, -34,-105,-106, -93; /M: SY='Q'; M= -88,-113, -84, -14,-117, -21, -79,-105, -71, -55, -88, -80, -96, 132, -27, -32, -91,-106,-103, -92; /M: SY='E'; M= -90,-111, -19, 115,-114,-105, -83,-114, -31,-107,-103, -86, -86, -16, -80, -86, -90,-107,-110,-103; /M: SY='C'; M= -95, 136,-111, -43, 81,-109,-105, -93,-106, -48, -90,-100,-118,-114,-110, -97, -93, -39,-100, -79; /I: I=-45; MD=-115; /M: SY='S'; M= -22, 59, -33, -87,-103, -29, -91, -34, 21, -66, -94, -37,-101, -14, 57, 70, -80, -7,-111, -97; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='S'; M= 41, -96, -14, -92, -91, -44, -23, -48, -94, 47, -7, -88,-100, -35, -96, 72, -79, -83,-107, -92; /M: SY='G'; M= -79,-105, -93, -41,-110, 99,-100,-111, -41,-111,-102, -81, -23, -94,-103, 16, -93, -20,-105,-106; /M: SY='R'; M= 15, 14, 31, -20,-103, -98, -89, -10, 23, -97, -91, 27,-101, -38, 72, -15, -86, 19,-111, -96; /M: SY='V'; M= -12, 28,-107,-103, -82, -50,-103, 19,-102, 51, 31,-100,-106,-100,-103, -24, 32, 52,-109, -89; /M: SY='V'; M= -43, -95,-101, -99, -89,-105,-106, -62, -96, -42, -79, -94, -27, -99, -37, -12, 72, 85,-117, -93; /M: SY='G'; M= -15,-104, -92, -41,-110, 96, -98,-114, -39, -53,-102, -80, -97, -92,-101, 32, -91,-107,-105,-105; /M: SY='F'; M= -49, 0,-113, -38, 104,-112,-102, 14,-106, -11, -77,-105,-111,-110,-105, -41, -91, 41, -84, -62; /M: SY='F'; M= -97,-104, -37, -37, 78,-114,-102, 76,-105, 19, 23,-104,-108,-104,-106, -41, -91, -31, -90, -27; /M: SY='W'; M= -55, -25, -99, -2, -43, 63,-106, -96, -36,-100, -97, -91,-100, -94,-100, 4, 19, 14, 127, -83; /M: SY='C'; M= -27, 65,-109, -37, -82,-109,-105, 38,-103, 42, 33,-103,-108,-100,-105, -14, -34, 57,-110, -90; /M: SY='V'; M= -4, -19, -14, 31, -52, -32, -23, -20, -88, -42, -85, 0,-100, -36, 2, 39, -9, 61,-112, -42; /M: SY='F'; M= -34, -22,-103, -54, 63, 51,-100, 20, -56, -2, -5, -22, 1, -38, -53, -29, -91, 22, -96, -81; /M: SY='D'; M= -87,-103, 41, 12, -99, -41, 34, -7, 0, -70, 0, 20, 10, 1, -31, 40, 33, -12,-111, 0; /I: I=-19; MD=-49; /M: SY='P'; M= -7, -25, 2, 15, -23, -2, -29, -61, -49, -30, -95, -5, 44, -88, 12, 34, 15, -24,-107, 15; D=-19; /I: I=-19; MD=-49; /M: SY='P'; M= -13,-106, -26, 11, -47, -33, 4, -45, 28, -56, -94, -39, 50, -4, 8, 38, 4, -4,-107, 2; D=-19; /I: I=-19; MD=-49; /M: SY='Q'; M= -59,-113, 12, 24,-108, -11, -97, -27, 12, -13, -28, -17, 4, 25, 3, 16, -10, -26,-116, -37; D=-19; /I: I=-19; MI=0; MD=-49; IM=0; DM=-49; /M: SY='S'; M= -15,-114, 11, 0,-116, -49, -37, -27, -5, -79,-106, 23, -26, -37, 15, 28, 8, -14,-126,-110; D=-19; /I: I=-19; DM=-49; /M: SY='R'; M= 15,-108, -29, -14, -57, 15, -29, -24, 13, -35, -97, -19, -14, -88, 38, 33, -31, -43,-108, 9; D=-19; /I: I=-19; DM=-49; /M: SY='P'; M= -6,-109, 23, 43,-107, -96, 13, -24, -15, -66, -34, 6, 80, 26, -59, 5, -32, -39,-110, -41; /M: SY='S'; M= 23, 20, -3, -8, -47, 17, -29, -42, -20, -23, -36, 11, -8, 8, -92, 45, 36, -38,-110, -97; /M: SY='T'; M= 38, -98, -45, -7, -31, -11, -7, 4, -35, -20, -87, -13, -25, -2, -94, 38, 44, -10,-105, 9; /M: SY='S'; M= 20, 0, -28, 31, -6, -8, 1, -2, -13, -27, -89, -25, -13, -38, 5, 38, 17, -10,-107, -40; /M: SY='P'; M= -2,-107, -7, 26,-105, -21, -92, -24, 36, -55, -12, -26, 71, -2, 11, 12, -58, -5,-109,-100; /M: SY='S'; M= 9, -28, 25, 12, -99, 23, -5, -94, -20, 4, -14, 4, 13, -21, -35, 34, 13, -28,-109, -33; /M: SY='S'; M= -12,-102, 9, 24,-105, -12, -23, -59, 17, -49, -18, 39, 25, 7, -40, 45, 27, -38,-112, -98; /I: I=-12; MD=-31; /M: SY='P'; M= -36,-127, -51, -11, -26, 0, -10,-117, -25, -27,-113, -27, 18, 14,-113, -24, 5, -42,-128, -40; D=-12; /I: I=-12; MI=0; MD=-31; IM=0; DM=-31; /M: SY='Q'; M= -3,-103, 15, 40, -47, -23, -22, -19, -14,-100, -94, 6, -4, 42, 2, 40, 34, -43,-110, -96; /M: SY='D'; M= 4,-106, 59, 13,-109, 26, -7, -68, 9,-104, -25, -34, 53, -18, -17, -55, 16, -18,-113,-100; /M: SY='T'; M= -17, -26, -33, -15, -89, -19, -27, 32, -32, 32, -22, -50, -27, 10, -97, 5, 43, 27,-109, -92; /M: SY='V'; M= -39,-100, -46, -14, -3, -43, -29, 26, -41, 18, 10, 33, -21, 18, -95, 13, 9, 39,-107, -39; /M: SY='V'; M= 18, 11, -55, -29, -43, -46, -29, 25, -52, 2, -2, -22, -42, -93, -32, 26, 35, 45,-110, -92; /M: SY='P'; M= 7, -4, -90, -21, -49, -36, -94,-101, 0, -74, -97, -22, 92, -2, -49, 50, 7, -60,-109,-102; /M: SY='S'; M= 1,-102, -17, -6, -95, -30, 6, 14, 20, -18, -87, -19, 7, 21, 10, 33, 21, -7,-105, 6; /M: SY='S'; M= 9,-103, 20, 8,-107, -23, -15, -38, 45,-102, -26, -11, -30, 33, 17, 54, -48, -42,-109, -96; /I: I=-29; MD=-75; /M: SY='P'; M= -19,-132, -31, -29,-129, -75, -30, -40, 10, -81, 10, -51, 28, -29, 14, -16, -65, -42,-134,-122; D=-29; /I: I=-29; MI=0; MD=-75; IM=0; DM=-75; /M: SY='Q'; M= -41,-104, 20, 24, -98, -43, -24, -2, 10, -4, -88, 25, -30, 59, -35, 32, -3, -7,-108, -15; /M: SY='Y'; M= -23,-104, -3, -10, 66, -44, -22, -39, 13, -3, 3, -45, -28, -9, -16, -4, -43, -36, -84, 71; /M: SY='K'; M= -21,-104, -9, 17,-102, -44, 0, -42, 45, -11, -90, 37, -1, 23, 41, -6, 15, -38,-109, -95; /M: SY='Q'; M= 7, -29, -38, -2, -21, -29, 7, -2, 10, -94, -23, 16, 25, 30, 24, 19, -18, 9,-104, 15; /M: SY='I'; M= -37,-100, -50, -59, 22, -34,-101, 50, -36, 31, 18, -46, -13, -97,-101, 6, 27, 29,-103, -85; /M: SY='K'; M= 7,-103, -19, -87, -52, -28, -23, 8, 46, -6, 30, -42, 3, -15, 7, 11, 18, -41, 38, 17; /M: SY='N'; M= 9,-102, 23, 15,-104, -40, 13, -99, 7, -10, -27, 55, 34, 8, -34, 32, 0, -97,-113, -97; /M: SY='Y'; M= 8,-102, -55, -25, -40,-100, -24, -27, 14, 33, -18, 1, 6, 15, -45, -3, 13, -13, -94, 62; /M: SY='I'; M= -21,-102, -31, -54, -7, -48, -12, 56, -50, 34, 42, -98, 0, -96, -19, -5, -10, 15, 23, -85; /M: SY='T'; M= -43, -99, -13, -14, -31,-101, -25, -29, 33, 15, 32, -85, 17, -87, -50, -18, 81, -37,-109, -92; /M: SY='G'; M= 26,-102, -16, 4,-107, 54, -24,-106, 8, -53, -97, 9, -13, 8, -2, 30, 4, -99,-108,-100; /M: SY='E'; M= 16, 5, -48, 65, -49,-100, 44, -33, -21, -1, -3, -44, -53, -3, 8, -6, 10, -13,-108, -32; /M: SY='D'; M= -46,-107, 79, 55,-111, -95, -34, -68, -12, -68,-102, 15, 39, -1, -88, 18, -6,-104,-117,-100; /M: SY='F'; M= -37,-105, -46,-100, 82, -47, -88, -27, -96, -20, -83, -97, 26, -21, -18, -16, 17, -59, 7, 79; /M: SY='S'; M= 1, 20, 46, -45, -61, -12, 44,-105, -56,-105, -98, 3, -8, -1, 18, 68, -15, -56,-115, -95; /M: SY='T'; M= -43, -98, 11, -85, -99, -61, -89, -19, 20, -9, -89, 51, -54, -31, 1, 48, 57, -14,-113, -95; /M: SY='E'; M= 1,-103, -17, 43, -44, -99, -94, 24, -6, -9, -9, -26, 18, 19, -28, 30, -31, 16, 13, -93; /M: SY='E'; M= -28,-104, 9, 75, -46, -23, -28, -57, -56, -14, -94, 1, 12, -36, -38, 42, 2, -38,-111, -97; /M: SY='D'; M= 25,-103, 48, -16,-105, 39, 13, -16, -7, -29, -94, 0, -31, -37, 22, 19, -50, -55,-111, -97; /M: SY='A'; M= 66, 0, -99, -95, -50, -62,-102, 29, -95, -51, -83, -32, -26, -50, -57, 6, 27, 38,-109, -95; /M: SY='S'; M= 2,-101, -51, -36, -52, -97, 14, -10, 23, 4, -8, -20, 7, 27, -2, 37, 23, 12,-107, -18; /M: SY='E'; M= 7,-104, -10, 57,-104, -10, -23,-102, -22, -54, -96, -38, 11, 11, 13, 47, 10, -43, 22, -38; /M: SY='S'; M= 52, -96, -92, -1, 17, -34, -93, -58, -54, 14, -30, -43, -58, -44, -11, 61, -3, -86,-104, -90; /M: SY='T'; M= -1, -98, 12, -91, -15, -39, 20, -25, -61, -43, -87, -16, -48, -90, -95, 30, 73, 11, -15, 47; /M: SY='T'; M= -5,-103, -24, 29,-100, -3, -15, -96, -15, -12, -40, -6, 7, 34, 25, 21, 44, -43, -8, -16; /M: SY='N'; M= -20,-100, -3, -11, -47, -55, -27, -18, 5, -22, -90, 61, -31, -13, 24, 17, 55, -27,-111, -35; /I: I=-7; MD=-18; /M: SY='W'; M= -6,-114, -55, -22, -7, -46, -34, -97, -26, 8, -31, -2, 2,-101, -2, -27, 25, -15, 71, -35; D=-7; /I: I=-7; MD=-18; /M: SY='S'; M= -22,-118, -59, 13, -45, -72,-110, -11, -3, 11, -99, -46, 18,-101, -40, 24, -17, -29,-123,-109; D=-7; /I: I=-7; MD=-18; /M: SY='P'; M= -38,-132, -53, -1,-136, -44, -34,-129, -5,-131,-123,-110, 36, 26, -64, 11, -1, -67,-136,-126; D=-7; /I: I=-7; MI=0; MD=-18; IM=0; DM=-18; /M: SY='R'; M= -73, -40,-125, -43, -37, -30, -24, -13, -7, -6,-111, -56, -54, -40, 13, -37, -33, -36,-133, -49; D=-7; /I: I=-7; DM=-18; /M: SY='K'; M= -64, -25, -3, -29, -62, -47,-113, -6, 20, -21,-108, -5, 0, 5, -35,-109, -8, -28,-127, -25; D=-7; /I: I=-7; DM=-18; /M: SY='H'; M= -31,-120,-103, 1,-119, 16, 28, -7, -9,-115,-108, -8, 10, -34, -15, 13, 10, -50,-126,-112; D=-7; /I: I=-7; DM=-18; /M: SY='L'; M= -9,-101, -53, -16, -29, -33, -96, 25, 18, 39, -23, 2, -6, -6, -54, -17, 6, 25,-105, -33; /M: SY='R'; M= -61, 1, -18, 1, -45,-103, 13, 11, 48, -1, -31, -8, -43, -4, 52, -16, -2, 0, 18, -90; /M: SY='D'; M= 3,-106, 79, -1, -45, -18, -3, -55, 1,-105,-100, 18, 34, 5, -25, -4, 4, -45,-116, -98; /M: SY='Y'; M= -27, -4, -26, 3, 43, -24, -88, -19, 30, -3, 28, -41, 4, -8, -5, 2, -23, -44, -91, 55; /M: SY='L'; M= -8, 12, -29, -7, 45, -44, -25, -27, -58, 51, 44, -25,-106, -1, -50, -55, -2, 3, -99, -40; /M: SY='W'; M= -58, -23, -22, -9, 8, -18, -10, 15, -7, 27, -26, -41, 22, -1, 6, -25, -30, 20, 46, 12; /M: SY='R'; M= -15,-107, 10, 22,-103, -7, 1, -39, 31, -13, -41, -37, -6, -2, 40, 28, -31, -41, -13, -41; /M: SY='R'; M= -95,-111, -31, -15,-105, -65, 7, -64, 36, -60, -94, 6, -47, -19, 92, -34, -11, -26,-109, -43; /I: I=-12; MD=-31; /M: SY='P'; M= -18, -25, -6, -9, -34, -25,-116, 4, -12, -38, 0, -50, 14, -40, -58, -21, -9, -25,-128,-114; D=-12; /I: I=-12; MD=-31; /M: SY='G'; M= -24,-133, -58, -41, -62, 19, -50, -15, -58, -76,-117, -24, 10, -42, -62,-114, -34, -1,-135, -41; D=-12; /I: I=-12; MI=0; MD=-31; IM=0; DM=-31; /M: SY='C'; M= -38, 16, -14, -13, -53, -47,-118, -33, -12, -2, -28, 1, 10,-113, -36, -35, -35, -62,-134,-120; D=-12; /I: I=-12; DM=-31; /M: SY='H'; M= -30,-106, -98, -15, -29, -43, 36, 20, 7, 16, 34, -18, -44, 13, -7, -13, -14, 8, 27, 30; /M: SY='N'; M= 7,-105, -31, -15, -44, 27, 36, -65, 31, -57, -96, 38, 15, -18, -22, 17, -25, -16, 3, -38; /M: SY='V'; M= -4, -6, -47, -9, 13,-105, -98, -39, 3, 4, 24, -19, 1, -33, 13, -21, 23, 45,-108, -91; /M: SY='D'; M= -45, -19, 80, 14,-111, -15, 15, -45, -15,-109,-104, 19, 13, -42, -18, 21, -88, -25, -1,-100; /M: SY='Y'; M= 0,-105, 13, -54, 18, -62, -37, 30, -54, 19, 39, -42,-106, 15, -51, -93, 11, 1, -98, 41; /M: SY='P'; M= -11, -25, 5, 30, -49, -26, -24, -31, -7, -2, -93, 4, 51, 27, -14, 5, 6, -44,-112, -99; /M: SY='S'; M= -47, 10, -20, 0,-106, -3, -94,-100, 16, -27, -35, -6, 25, 3, 10, 50, 31, -27,-113,-100; /M: SY='I'; M= 10,-103, -60, -60, -28, -42,-102, 44, -27, 34, -22,-101, -25, -43,-102, -10, -8, 27,-103, 20; /M: SY='E'; M= 5, -37, 26, 38,-104, -17, -95, -14, 16, -29, -93, -18, -25, -39, 17, 11, -10, 15,-114,-100; /M: SY='G'; M= 15,-107, -15, -4,-111, 59, -25,-107, 29, -56, -33, -17, 20, -1, -29, -14, -21, -46,-110,-103; /M: SY='T'; M= 27, 1, -27, -25, -5, -41, -94, -97, 32, -36, -94, 10, -45, 0, 23, -3, 35, -26, 27, -15; /M: SY='W'; M= -6, -32, 1, 6,-102, 11, -13, -14, 16, -60, 19, 7,-101, -13, 34, 19, -11, -19, 47, -50; /M: SY='T'; M= -35,-104, -10, 26,-107, -29, -40, -44, 22, -58, -97, 11, 26, 4, -26, 41, 52, -59,-114,-101; /M: SY='T'; M= 2,-105, 15, -8, -62, -29, -9,-102, 16, -52, -33, -3, 0, 17, 26, 29, 40, -48,-113, -41; /I: E1=0; IE=-380; DE=-380;» more |
Post-processing [info]
| COMPETES_HIT_WITH | PS51726; PS51727 |
Numerical results [info]
| Total number of hits | 5 in 5 different sequences |
| Number of true positive hits | 5 in 5 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | Rtt109-type HAT |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
5 sequences
RT109_ASPFL (A0A364LXP7), RT109_CANAL (Q5AAJ8), RT109_PNECA (D3G9N3), RT109_SCHPO (Q9Y7Y5), RT109_YEAST (Q07794)» more
|
| PDB [Detailed view] |
16 PDB
2RIM; 2ZFN; 3CZ7; 3Q33; 3Q35; 3Q66; 3Q68; 3QM0; 6O22; 7BWZ; 7BX0; 7BX1; 7BXW; 7C3O; 8GQ3; 8GQ4 » more |