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PROSITE entry PS51726


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51726
Entry name [info] MYST_HAT
Accession [info] PS51726
Entry type [info] MATRIX
Date [info] 01-JUL-2014 CREATED;
01-JUN-2016 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51726
Associated ProRule [info] PRU01063

Name and characterization of the entry

Description [info] MYST-type histone acetyltransferase (HAT) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=275;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=270;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.5242666; R2=0.0090946; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=932; N_SCORE=10.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=548; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Post-processing [info]

COMPETES_HIT_WITH PS51727; PS51728

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 42 in 42 different sequences
Number of true positive hits 42 in 42 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] MYST-type HAT
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
42 sequences

ESA1_ASPFU  (Q4WHG1), ESA1_ASPOR  (Q2UMQ5), ESA1_CANAL  (Q5A7Q2), 
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PDB
[Detailed view]
58 PDB

1FY7; 1M36; 1MJ9; 1MJA; 1MJB; 2GIV; 2OU2; 2OZU; 2PQ8; 2RC4; 2Y0M; 3QAH;
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