PROSITE entry PS51718
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS51718 |
| Entry name [info] | G_DYNAMIN_2 |
| Accession [info] | PS51718 |
| Entry type [info] | MATRIX |
| Date [info] |
01-MAY-2014 CREATED;
07-APR-2021 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00362 |
| Associated ProRule [info] | PRU01055 |
Name and characterization of the entry
| Description [info] | Dynamin-type guanine nucleotide-binding (G) domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=273; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=268; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.0734248; R2=0.0082282; TEXT='-LogE'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=47981.0000000; R2=0.0000000; PRIORITY=1; TEXT='Heuristic 0.5%'; /CUT_OFF: LEVEL=0; SCORE=1572; H_SCORE=47981; N_SCORE=15.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=538; H_SCORE=47981; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-32; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='Q'; M= -13, -75, 23, 1, 32, -21, 45, -5, -8, -66, -62, -52, 31, 55, -57, 44, -54, -65, -74, -55; /M: SY='D'; M= -19, -75, 55, -54, 27, -74, -62, 15, -52, 22, -52, -57, -74, 11, 51, -61, 3, -8, -75, -55; /M: SY='D'; M= -16, -73, 51, 24, -73, -12, 49, -67, -54, -19, -63, 11, 3, -53, -3, 21, 36, -15, -87, -64; /M: SY='H'; M= -13, -70, -61, -1, -1, -70, 52, -8, 22, 31, -50, 7, -70, -55, 3, 17, 25, -9, -77, -56; /M: SY='P'; M= -62, -80, -70, -61, 1, -68, -65, -59, -64, -22, 80, -69, 105, -63, -71, 16, -57, -64, -75, -65; /M: SY='M'; M= 7, -73, -53, 46, -73, -68, -57, -64, 54, -64, 55, 3, -65, 7, 28, -10, -11, -9, -77, -65; /M: SY='V'; M= -59, -70, -84, -79, 12, -86, -81, 63, -77, 22, -38, -78, -78, -76, -78, -70, -56, 73, -76, -55; /M: SY='V'; M= 42, -66, -79, -72, 3, -73, -75, -32, -72, 40, -42, -75, -77, -71, -73, -61, -55, 69, -77, -58; /M: SY='F'; M= 4, -69, -83, -78, 75, -80, -77, 37, -76, -8, -44, -76, -79, -78, -76, -67, -57, 63, -63, -42; /M: SY='V'; M= -60, -69, -81, -77, 46, -83, -78, 44, -74, 21, -41, -74, -77, -76, -76, -66, 23, 66, -72, -50; /M: SY='G'; M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78; /M: SY='D'; M= -61, -79, 68, -45, -80, 5, -56, -76, 3, -75, 19, 5, 36, 40, 40, -10, 2, -74, -83, -68; /M: SY='Q'; M= -60, -76, 6, -50, -62, -72, -56, -55, -51, -15, 53, -57, -69, 89, 1, -54, 38, 8, 58, 17; /M: SY='S'; M= -46, -66, -54, -56, -75, 15, -58, -75, 20, -78, -70, 33, -65, -50, -56, 89, 4, -69, -82, -68; /M: SY='N'; M= 43, -66, 40, -53, -75, -56, -59, -66, -55, -71, -66, 51, -67, -54, -2, 48, 25, -7, -86, -68; /M: SY='G'; M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78; /M: SY='K'; M= -63, -77, -55, -41, -79, -70, -58, -79, 110, -78, -66, -48, -63, -39, -24, -57, -57, -75, -72, -65; /M: SY='S'; M= -42, -64, -56, -57, -73, -51, -60, -72, -57, -76, -69, -44, -63, -50, -62, 104, 30, -64, -83, -66; /M: SY='S'; M= 45, -62, -59, -59, -72, -54, -64, -66, -58, -70, -64, -49, -63, -55, -64, 72, 69, -57, -82, -67; /M: SY='V'; M= -60, -67, -80, -75, 45, -82, -73, -31, -73, 45, 32, -74, -78, -73, -74, -66, 25, 63, -71, -49; /M: SY='I'; M= -65, 57, -85, -81, -47, -87, -78, 79, -78, 52, -35, -78, -79, -75, -79, -73, -60, 2, -75, -57; /M: SY='N'; M= -61, -74, -34, 81, -80, -62, -48, -80, -43, -80, -71, 93, -64, -41, 4, -50, -54, -78, -87, -72; /M: SY='A'; M= 71, -64, -62, -60, -67, -53, 29, -66, -60, -66, 28, 0, -67, -55, -63, 56, -48, -58, -74, 18; /M: SY='L'; M= -67, -71, -85, -78, 46, -85, -69, 36, -77, 71, 52, -80, -81, -72, -75, -76, -63, -37, -65, -46; /M: SY='I'; M= 6, -69, -81, -75, -49, -79, -74, 55, -74, 50, 28, -75, -77, -70, -75, -12, -56, 39, -76, -57; /M: SY='G'; M= -54, -79, -60, -3, -77, 84, 71, -87, -9, -80, -69, -50, -68, 16, -64, -52, -67, -83, 50, -63; /M: SY='F'; M= -11, -75, 0, 36, 55, -74, 21, -17, 0, -14, -56, -59, -70, 38, 34, -59, 2, -14, -68, -49; /I: I=-38; MD=-97; /M: SY='D'; M= -15, -84, 42, 37, -86, -71, -58, -83, 35, -81, -72, 7, 34, 37, 39, -59, -62, -80, -84, -73; D=-38; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='F'; M= -17, -71, -81, -76, 70, -80, -71, 38, -70, 20, 32, -74, -79, -72, 1, -20, -59, 39, -63, -43; /M: SY='L'; M= -66, -70, -68, -70, 11, -74, -59, -42, -68, 69, 33, 56, 8, -65, -69, -67, -59, -49, -68, 20; /M: SY='P'; M= -64, -86, -68, -59, -75, -11, 25, 32, -64, -67, -60, -68, 108, 15, -72, -63, -59, -14, -79, -72; /M: SY='R'; M= -56, -73, -58, 20, -68, -7, -59, -57, -6, -15, 27, 10, -69, 13, 55, 32, -4, 26, -79, -64; /M: SY='G'; M= -10, -78, 42, 35, -75, 71, -60, -84, -54, -79, -72, -50, -67, -54, 26, -53, -64, -78, -73, 17; /M: SY='M'; M= -53, -71, -61, -8, -68, 29, -62, 18, -58, -58, 52, 11, -67, 49, -62, 40, 25, 11, -79, -64; /M: SY='G'; M= -53, -74, -55, -9, -78, 78, -60, -80, -57, -27, -68, 55, -69, 14, 2, 1, -60, -77, -78, -72; /M: SY='P'; M= -9, -77, -62, -1, -68, -16, 70, 35, -62, -59, 45, 6, 71, -58, -66, -1, 0, -55, -81, -61; /M: SY='C'; M= -16, 82, -66, 22, -63, 6, -69, 17, -6, -11, 55, -63, -71, -62, -67, -58, 24, 22, -82, -66; /I: I=-16; MI=0; MD=-40; IM=0; DM=-40; /M: SY='T'; M= -72, -83, -81, -83, -86, -89, -90, -70, -80, -80, -78, -71, -83, -83, -87, -7, 83, 10,-108, -85; D=-16; /I: I=-16; DM=-40; /M: SY='R'; M= -17, -99, -87, -76, 26, -94, -77, -94, -4, -87, -82, -79, -95, -67, 79, -81, -84, -90, -88, -73; D=-16; /I: I=-16; DM=-40; /M: SY='R'; M= -21, 56, -79, -72, -82, -83, -74, -79, -55, -22, -73, -71, -87, -65, 70, 16, -1, -26, -94, -78; D=-16; /I: I=-16; DM=-40; /M: SY='P'; M= -72, -94, -70, 19, -91, -79, -78, -78, -70, -87, -78, -77, 100, -70, -80, -7, -3, -16, -91, -88; D=-16; /I: I=-16; DM=-40; /M: SY='L'; M= -15, 32, -82, -79, -56, -85, -80, 41, -78, 46, -44, -76, -80, -76, -80, -67, 38, 19, -83, -65; D=-16; /I: I=-16; DM=-40; /M: SY='H'; M= -68, 29, -72, -13, 7, -83, 57, 38, -5, 5, -52, 2, -79, -68, -69, -68, -2, 23, -78, 14; D=-16; /I: I=-16; DM=-40; /M: SY='C'; M= -69, 74, 0, -11, -57, -88, -77, 45, -78, 46, 14, -77, -84, -74, -80, -75, -65, -2, -84, -66; D=-16; /I: I=-16; DM=-40; /M: SY='Q'; M= 8, -78, -64, -7, 26, -73, 26, -73, -7, -70, -64, -58, -72, 71, 21, -54, 50, -69, -78, -60; D=-16; /I: I=-16; DM=-40; /M: SY='M'; M= -69, -76, -80, -5, 5, -87, 29, -42, -71, 57, 65, -78, -83, -68, -6, -76, -67, 15, -78, -56; D=-16; /I: I=-16; DM=-40; /M: SY='Q'; M= -61, -76, -68, -7, -69, -75, -67, 12, 16, 4, 30, -62, -73, 50, -60, 31, 25, 8, -83, -66; D=-16; /I: I=-16; DM=-40; /M: SY='N'; M= -13, -78, -56, -1, -7, -69, 22, -68, -7, -73, -67, 74, 9, -57, 33, -59, -60, 9, -81, 13; D=-16; /I: I=-16; DM=-40; /M: SY='N'; M= -60, -75, 53, 33, -72, 16, -54, -74, -55, -27, -68, 61, 37, -53, -63, 8, -5, -73, -80, 12; /M: SY='P'; M= -7, -74, -65, -62, -74, 54, -68, -8, -14, -25, -62, -57, 60, 14, -67, 10, 27, -15, -77, -71; /M: SY='S'; M= -54, -70, 3, -52, -73, -61, 31, -12, 22, -71, -64, 28, 7, 14, 6, 56, 50, -63, -83, -64; /I: I=-8; MD=-20; /M: SY='D'; M= -80, 28, 42, 33, -2, -86, -76, -91, -12, -31, -85, 7, -9, -70, -77, -6, -74, -89, -99, -82; D=-8; /I: I=-8; MI=0; MD=-20; IM=0; DM=-20; /M: SY='C'; M= 10, 62, -50, 60, -77, -14, 30, -77, 31, -74, -67, -53, -64, 15, -52, 30, 2, -69, -81, -68; /M: SY='F'; M= -15, -73, -62, 36, 59, 9, -65, -53, -7, -20, -57, -1, -6, -61, -64, -11, -59, 29, 48, 8; /M: SY='H'; M= 21, -76, -51, 54, -70, -15, 56, -7, 17, -69, -62, 1, 33, -48, -3, -54, 3, -65, -76, 11; /M: SY='V'; M= 24, -71, -70, -13, -62, -17, -70, 13, 19, 4, 29, -66, 34, -61, -63, -9, -55, 48, -78, -64; /M: SY='W'; M= -62, 30, -3, -66, 28, -14, -66, 34, 17, -11, 23, 3, -74, -64, -5, -61, 19, 16, 39, 19; /M: SY='M'; M= -18, 25, -69, -66, -56, -74, 53, 17, -3, -3, 69, 2, 9, -62, -64, -60, 22, 30, -76, 18; /M: SY='H'; M= -64, -75, 26, 31, -58, -74, 91, -7, -58, 35, -49, -55, -70, -53, -4, -10, 4, -59, -79, 12; /M: SY='G'; M= -57, 20, -64, -62, 54, 56, -59, -71, -6, -66, -63, 4, -72, 52, -61, 18, -60, -70, -61, 32; /M: SY='P'; M= -10, -75, -56, 20, -70, -65, -60, 12, 33, 3, -57, 25, 50, 33, -54, 33, -53, -60, -77, -67; /M: SY='D'; M= -62, -77, 92, -38, -82, -65, -54, -79, 2, -78, -72, -41, -66, 38, 29, 11, 26, -75, -90, -67; /M: SY='E'; M= -63, -77, 45, 56, -65, -13, -52, -71, 26, -18, 16, 45, 11, -48, -53, -57, -58, -71, -73, 39; /I: I=-21; MD=-53; /M: SY='W'; M= -75, -89, 23, -9, 4, -81, 27, -9, 30, -80, -76, 5, 2, -65, -7, -6, -4, -78, 48, -67; D=-21; /I: I=-21; MI=0; MD=-53; IM=0; DM=-53; /M: SY='K'; M= -66, -81, -73, -10, -74, -11, -76, 29, 32, -25, 26, -66, -77, -65, -66, 28, 22, -20, -88, -73; D=-21; /I: I=-21; DM=-53; /M: SY='Y'; M= -61, -77, 2, 20, -53, -10, -52, -66, 45, -20, -59, -56, 3, 9, 7, 18, -58, -23, -59, 74; /M: SY='E'; M= -59, -73, -57, 45, -5, -73, -63, 14, -2, 7, 25, 0, 27, 8, -61, -1, 26, 14, -77, -61; /M: SY='I'; M= -57, -70, -64, -1, 4, -73, -68, 43, 32, -11, -50, 10, -70, -59, -59, 17, 31, 39, -77, -59; /M: SY='D'; M= -11, -75, 80, 5, 4, -64, 23, -73, -10, -71, 22, -46, 33, -54, -61, 30, -2, -70, -84, -62; /I: I=-45; MD=-115; /M: SY='L'; M= 19, -73, -7, -17, -4, 15, -70, -52, -69, 38, -52, -66, 34, -66, -73, -2, -4, 10, -77, -64; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='N'; M= 11, -70, -5, -15, -2, -11, 26, 20, -61, -20, -56, 47, -70, -57, -65, 42, -2, -6, -74, 20; /M: SY='E'; M= 34, -75, 4, 62, -79, -67, 14, -71, 32, -71, -64, -54, -63, 55, 6, -52, -58, -8, -78, -66; /M: SY='L'; M= -15, -71, 2, 13, 11, -81, -69, 42, -70, 51, 32, -72, -75, -66, -72, -68, -59, 25, -73, -54; /M: SY='A'; M= 49, -70, 6, -7, -68, -12, -64, -6, -4, 3, -55, -59, -70, 13, 36, -53, -3, 12, -78, -65; /M: SY='H'; M= 11, -75, -1, 14, -74, -67, 81, -67, 53, -69, -61, -52, 4, 6, 8, -3, -57, 12, -82, -59; /M: SY='D'; M= 42, -73, 44, 44, -70, -63, -57, -67, -50, -22, -62, -54, -67, 19, 22, 16, -55, -15, -76, 13; /M: SY='I'; M= -64, -75, -75, -8, -51, -82, 27, 74, -71, 45, 22, -71, 9, -66, -73, -5, -59, -34, -75, -56; /M: SY='E'; M= -9, -75, 7, 56, -72, -69, 24, -10, -47, -25, -60, 3, -66, 36, 35, 19, -56, 12, -81, -64; /M: SY='M'; M= 17, -75, 23, -3, -63, -69, -58, -58, -6, 7, 46, -60, 33, 12, 41, -10, -58, -7, -73, 16; /M: SY='E'; M= 2, -77, 28, 53, -77, -10, -57, -76, -1, -23, -66, -53, 10, 12, 49, 23, -57, -71, -79, -68; /M: SY='N'; M= -11, -68, -59, -61, 48, -67, -58, -55, 17, -1, 56, 58, -70, 7, -58, -52, 53, -56, -71, -51; /M: SY='N'; M= -58, -74, 35, 35, -73, -14, -56, -66, -49, -19, 24, 43, 11, 13, 28, 33, -53, -8, -83, -67; /M: SY='K'; M= 20, -72, 2, -5, 5, -65, -59, -65, 54, -22, 17, 33, 12, -50, 22, 0, -55, -22, -75, -62; /M: SY='W'; M= -18, -72, -73, -67, 5, -17, -66, 11, -9, 44, -47, -66, 8, -62, -5, 36, -57, -13, 56, 12; /M: SY='A'; M= 53, -68, -56, 39, -72, -60, -64, -59, -58, -24, -60, 9, 33, -54, -64, 21, 18, 12, -80, -70; /M: SY='K'; M= 11, -74, 0, -57, -66, 40, -62, -3, 46, -22, 26, -54, 1, 13, -54, -8, 1, -61, -71, 17; /M: SY='E'; M= -10, 27, -61, 35, 33, -17, -63, -56, -8, 18, 24, -61, -70, -55, 22, 15, 16, -10, -72, -56; /M: SY='G'; M= 10, -73, 1, -60, -71, 54, -64, -6, 32, 1, -61, 28, 7, -58, -59, -9, -4, -63, -77, -69; /M: SY='Q'; M= -60, 29, -59, -7, -67, -16, -56, 17, 26, -60, 20, 31, -71, 77, 7, -56, -58, 13, -73, 13; /M: SY='Y'; M= 23, -71, 25, 0, -63, 18, -57, -64, -54, -21, -61, 37, -69, -55, 20, -3, 23, -9, -72, 39; /M: SY='V'; M= -16, -72, -5, -63, 33, -73, 29, 29, -62, -51, -51, 8, 7, 16, -5, -6, 0, 53, -76, -54; /M: SY='S'; M= -57, -69, -63, -9, 28, -68, -62, 0, 19, 21, 28, 33, -72, -58, -60, 46, -51, 25, -74, -55; /M: SY='D'; M= -11, -76, 50, 35, -72, -65, 22, -14, -57, -22, -65, 11, 49, -53, -64, 30, 5, -66, 49, -64; /I: I=-36; MD=-90; /M: SY='P'; M= -18, -95, -5, -76, -88, -13, -81, -86, 17, -92, -86, -1, 28, -76, -77, 16, -73, -14, -94, 10; D=-36; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='E'; M= 2, -76, -52, 55, -65, -72, 26, 17, 35, -23, -57, 9, -67, -46, 41, -58, -59, -17, -74, 13; /M: SY='P'; M= -66, -82, -65, -3, 31, -72, -66, -64, 15, 2, -60, -67, 100, -61, 1, -62, 2, -67, -72, -63; /M: SY='I'; M= 8, 57, -81, -76, -53, -80, -77, 80, -9, 16, 30, -72, -75, -70, -73, -67, -58, 3, -76, -60; /M: SY='H'; M= -14, 32, -59, 1, 0, -8, 57, -8, -4, -64, -59, 0, -68, 6, -4, 34, 33, -14, -75, 14; /M: SY='L'; M= -11, -69, -74, -4, -50, -78, -70, 39, -70, 57, 23, -71, -74, -65, -72, -8, 19, 17, -76, -58; /I: I=-29; MD=-75; /M: SY='S'; M= -10, -79, -59, 35, -83, -70, 13, -82, -3, -81, -73, -57, -71, 16, 34, 52, 23, -75, -88, -72; D=-29; /I: I=-29; MI=0; MD=-75; IM=0; DM=-75; /M: SY='V'; M= -19, -80, -85, -10, -63, -14, -87, 43, -82, 19, -51, -83, -85, -79, -84, -75, -66, 53, -88, -70; D=-29; /I: I=-29; DM=-75; /M: SY='E'; M= -71, 28, -64, 45, -74, -82, -69, -73, 28, 16, -66, -71, 36, 12, -62, -13, -68, -74, -82, 3; D=-29; /I: I=-29; DM=-75; /M: SY='H'; M= -68, -85, -66, -3, 0, -10, 57, -82, -16, -78, -71, 8, -80, -60, 21, 37, -65, -80, -72, 57; D=-29; /I: I=-29; DM=-75; /M: SY='P'; M= 15, -83, -68, -64, -84, -71, -68, -80, 21, -26, -72, 30, 48, -60, 40, 15, -63, -77, -88, -78; D=-29; /I: I=-29; DM=-75; /M: SY='H'; M= -61, -74, -4, -66, -49, 35, 64, -54, -64, 37, -49, -59, -74, -62, -8, -59, 20, -8, -65, 60; /M: SY='C'; M= -17, 71, 2, -62, -58, -75, -67, 22, -62, 8, -50, -64, 10, 36, -4, -59, 21, 31, -76, 19; /M: SY='P'; M= -61, -77, 27, 2, -66, -9, -60, -61, -6, 15, -58, 6, 72, 16, -63, -9, 2, -14, -75, 15; /M: SY='D'; M= -62, -76, 79, -44, -82, -10, -51, -81, -48, -82, -73, 74, 2, 16, 29, -1, -54, -79, -91, -70; /M: SY='L'; M= -63, -70, -84, -78, -45, -85, -72, 47, -76, 65, 58, -79, -79, -71, -75, -74, -59, 34, -74, -55; /M: SY='T'; M= -8, -65, -60, -5, -65, -66, -67, -48, -9, -13, -55, 5, -66, -59, -63, 32, 76, 40, -84, -65; /M: SY='L'; M= -67, -72, -85, -79, 13, -87, -72, 60, -78, 72, 18, -80, -80, -72, -77, -76, -62, -33, -69, -51; /M: SY='I'; M= -60, -72, -84, -80, -48, -86, -78, 76, -76, 11, 30, -77, -77, -74, -77, -71, -56, 61, -74, 11; /M: SY='D'; M= -67, -81, 117, 10, -88, -65, -53, -86, -54, -84, -83, -36, -66, -53, -63, -56, -57, -83,-102, -71; /M: SY='T'; M= -9, -65, -64, -63, -61, -65, -66, -53, -62, 38, -51, -55, 13, -60, -67, 51, 74, -52, -80, -63; /M: SY='P'; M= -66, -92, -67, -55, -86, -68, -70, -74, -63, -84, -70, -73, 128, -66, -75, -64, -59, -79, -79, -83; /M: SY='G'; M= -48, -76, -64, -75, -82, 101, -70, -90, -69, -86, -75, -50, -68, -66, -76, 2, -65, -83, -74, -77; /M: SY='I'; M= -63, -72, -81, -76, 27, -84, -73, 51, -75, 44, -38, -76, 9, -73, -76, -69, -3, 44, -69, 9; /I: I=-26; MD=-67; /M: SY='N'; M= -65, -76, 52, -61, -70, -71, -65, 44, -65, -19, -60, 60, -74, -64, -71, -1, 30, -12, -92, -69; D=-26; /I: I=-26; MI=0; MD=-67; IM=0; DM=-67; /M: SY='Q'; M= 10, -85, -2, -2, 0, -82, -75, -67, -15, -2, -67, -72, -84, 30, 14, -5, -69, 11, -87, -72; D=-26; /I: I=-26; DM=-67; /M: SY='T'; M= -65, -77, -1, -67, -72, -78, -73, -1, -10, -18, -62, 10, 6, -66, 18, -7, 50, 30, -91, -72; D=-26; /I: I=-26; DM=-67; /M: SY='P'; M= 21, -80, -66, 16, -82, -13, -72, -14, -9, -74, -69, -65, 41, 11, 2, -4, 24, -9, -86, -76; D=-26; /I: I=-26; DM=-67; /M: SY='E'; M= 7, -71, -59, 35, -67, 11, -65, 0, 19, -17, 21, -58, -66, 15, -58, -5, 27, 31, -79, -65; /M: SY='Q'; M= 8, -75, 40, 1, 1, 21, -58, -68, 17, 1, -60, -3, -68, 57, 1, -53, 2, -67, -76, -62; /M: SY='D'; M= -12, -74, 67, -4, -82, 47, -56, -82, -2, -81, -73, 47, -67, 17, -59, 19, -55, -77, -85, -71; /M: SY='Q'; M= -57, -77, 6, 55, -75, -68, -52, -68, -45, -22, 54, -53, -64, 86, 3, 30, -56, -68, -77, -63; /I: I=-15; MD=-37; /M: SY='P'; M= 8, -97, -83, -74, -98, -81, -82, -93, -67, -96, -86, -80, 71, -73, 39, 18, -73, -89, -97, -91; D=-15; /I: I=-15; MI=0; MD=-37; IM=0; DM=-37; /M: SY='G'; M= -19,-103, -86, -18, -99, 39, -89,-106, 29,-105, -95, -80, -1, -80, -79, -79, -88,-101, -96, -5; D=-15; /I: I=-15; DM=-37; /M: SY='Y'; M= -88,-100, -5, 13, -66, -92, -67, -90, -74, -88, -83, 32, -95, -74, -4, -79, -12, -91, -75, 75; D=-15; /I: I=-15; DM=-37; /M: SY='E'; M= -18, -96, 3, 34, -99, -87, 28, -96, 28, -93, -84, -70, 10, 25, -65, -71, -1, -91, -99, -84; D=-15; /I: I=-15; DM=-37; /M: SY='I'; M= -84, -93,-105,-101, 32,-106, -96, 66, -96, -13, 30, -95, -95, -94, -97, -92, -78, -6, -85, -65; D=-15; /I: I=-15; DM=-37; /M: SY='E'; M= -15, -92, -72, 18, 3, -11, -76, -88, 10, -30, -80, 9, -86, 13, -9, 7, -74, -86, -91, -79; D=-15; /I: I=-15; DM=-37; /M: SY='D'; M= 8, -90, 38, 20, -98, -26, -78, -95, -5, -95, -89, -66, -82, -68, -76, 31, -8, -87,-102, -88; D=-15; /I: I=-15; DM=-37; /M: SY='M'; M= -63, 32, -81, -71, -51, -79, -67, 23, -5, 28, 99, -73, -75, 8, -65, -70, -61, 19, 80, -52; /M: SY='I'; M= -58, 57, -77, -75, -54, -78, -77, 63, -72, 23, -43, -68, -75, -70, -75, 18, 24, 39, -80, -61; /M: SY='K'; M= 5, -72, 42, 20, -72, -66, -57, -67, 43, -3, 11, 12, -66, 18, 3, -4, 28, -64, -81, -65; /M: SY='W'; M= 12, -75, -56, 29, -73, -11, -61, -76, 50, -75, -67, -53, -65, 55, -47, 44, -55, -72, 86, -60; /M: SY='Y'; M= -68, -76, -73, -69, 58, -79, 27, -48, -7, 16, -46, -70, -80, 14, -62, -67, -63, 13, -45, 95; /M: SY='C'; M= 21, 74, -79, -75, 8, -75, -72, 48, -72, 19, 68, -70, -76, -70, -74, -62, 4, -3, -75, -57; /M: SY='Q'; M= 12, -73, 8, 32, -72, -64, -56, -65, 2, 1, 26, 7, -66, 64, 1, 28, -5, -64, -78, -64; /M: SY='R'; M= -19, 32, 42, -51, -78, -66, 51, -79, -44, -77, -68, 34, 55, -51, 67, -1, -58, -76, -86, -66; /M: SY='Q'; M= 45, 28, -58, -8, -78, -60, -60, -67, 18, -71, -63, 32, 47, 61, -55, -3, -54, -10, -79, -70; /M: SY='D'; M= -62, -76, 71, 53, -80, -62, 68, -82, -50, -79, -71, 60, -65, -46, -57, 16, -54, -79, -93, -64; /M: SY='R'; M= 35, -71, -63, 19, 3, -68, -64, -10, -49, -14, -55, -62, -70, -53, 60, 8, -4, 28, -76, -61; /M: SY='I'; M= -65, -74, -84, -81, 46, -87, -80, 90, -77, 7, -38, -74, -76, -76, -79, -70, 4, 5, -67, -48; /I: I=-45; MD=-115; /M: SY='I'; M= -70, -80, 24, -76, 9, -88, -80, 64, -80, 29, -47, -75, -83, -77, -82, -14, -64, 15, -81, -61; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='L'; M= -11, -69, -83, -76, -45, -83, -73, 23, -76, 72, -33, -80, -81, -72, -75, -71, -59, 43, -75, -56; /M: SY='V'; M= 19, 58, -78, -74, 45, -75, -75, -34, -73, 8, -47, -9, -80, -75, -74, -63, -55, 71, -74, -53; /M: SY='V'; M= -15, 30, -82, -77, 34, -80, -77, 44, -75, 30, -41, -75, -79, -74, -76, -8, -56, 60, -73, -53; /M: SY='N'; M= -61, -73, 47, 37, 28, -68, -56, -58, -55, -2, 23, 48, -69, 38, -60, -10, -7, 7, -78, -57; /M: SY='P'; M= 35, -73, 5, -2, -70, -63, -61, -62, -55, -68, -62, -58, 58, 33, -2, 28, 5, 12, -75, 16; /M: SY='S'; M= 37, 29, 3, 35, -73, -7, 29, -63, -58, -68, -63, -53, -65, -54, -64, 43, 28, 12, -84, -67; /M: SY='S'; M= -50, -67, -1, -52, -76, -54, -54, -74, 23, -77, -68, 65, -65, 17, -53, 76, 23, -69, -85, -67; /M: SY='Q'; M= 10, -67, -66, -61, -61, -69, -65, -41, -61, 22, 17, 11, -71, 51, -64, -4, 39, 50, -80, -62; /M: SY='D'; M= -18, -78, 85, 46, -76, -7, -58, -68, -1, -1, -66, -48, 7, -52, -60, -57, -58, -11, -87, -69; /M: SY='W'; M= -9, 28, -70, -70, -6, -7, -70, 17, -66, -3, 22, 31, -73, -64, -70, 33, 0, -5, 109, -52; /M: SY='T'; M= 29, 25, -56, 20, -74, -7, 29, -6, -4, -68, -62, 6, -66, 36, 3, 21, 37, -61, -81, -65; /M: SY='N'; M= -12, -68, 4, -62, 6, -65, -61, 16, -58, 18, -53, 56, -71, -59, 2, 33, 33, -6, -79, -59; /I: I=-38; MD=-97; /M: SY='S'; M= -11, 16, 5, 35, -79, -12, -66, -74, -61, -74, 22, -54, -68, -56, -68, 57, 48, -68, -89, -73; D=-38; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='E'; M= -57, -75, -2, 69, -72, -69, -59, 16, 19, -24, -62, -54, -63, -44, 24, 42, 1, -60, -79, -66; /M: SY='M'; M= 46, -69, -63, -1, 6, -63, 24, -56, -57, -13, 54, 6, -69, 14, -1, 11, 0, -6, 47, -56; /M: SY='F'; M= -62, -71, -68, -1, 45, -15, -65, -13, -7, 40, -47, -64, -74, -60, 38, -4, 26, -5, -69, -51; /M: SY='F'; M= -64, -78, 43, 38, 44, -72, -55, -69, 28, -64, 28, -54, 4, 13, 38, -10, -60, -69, -67, 15; /M: SY='L'; M= 3, -71, -73, -3, 30, -78, 23, 18, -5, 51, 44, -71, -76, -63, -66, -67, -61, -3, -66, 16; /M: SY='A'; M= 42, -69, 2, -5, 8, -68, -69, 19, -8, 6, -51, -63, -71, -60, -2, 8, -54, 39, -76, -59; /M: SY='K'; M= -59, -74, -61, -52, -69, -70, -59, -3, 65, -62, 24, 7, -69, 10, 50, 18, -54, 27, -77, -63; /M: SY='Q'; M= 34, -73, -52, 41, -69, -64, -55, -67, 43, 1, -58, 32, -66, 57, -47, -52, -57, -65, -72, 12; /M: SY='I'; M= 34, -69, -72, -8, -54, -72, -69, 43, -7, 24, 30, -69, -72, -63, -67, -4, -55, 34, -73, 9; /M: SY='D'; M= -62, -77, 92, -38, -81, -65, -56, -75, 56, -77, -73, -42, -66, -49, 1, 18, -54, -11, -88, -68; /M: SY='P'; M= -61, -79, -64, -62, -66, 29, -63, -65, -16, 15, -59, 8, 87, -62, -5, -9, 1, -67, -72, 18; /M: SY='E'; M= -57, -77, 3, 62, -80, -66, 30, -79, 21, -75, -67, -49, -63, 55, 28, 43, -10, -74, -80, -65; /M: SY='G'; M= -57, -74, -60, 23, 24, 49, -63, -66, 44, 18, -58, -56, -69, -54, 3, 17, -60, -66, -70, -59; /M: SY='S'; M= -56, -73, 43, -51, -70, -65, -61, -62, 19, 10, -60, -52, 49, 1, -4, 53, -3, -9, -81, -66; /M: SY='R'; M= -65, -78, -57, -52, -74, -70, 30, -75, 5, -25, -61, 48, 10, 19, 89, -56, -2, -73, -80, -62; /M: SY='T'; M= -55, -66, -68, -68, -57, -73, -71, 47, -65, 8, 23, -58, -67, -65, -70, 21, 78, 16, -81, -61; /M: SY='I'; M= -68, -75, -80, -77, 73, -84, -70, 74, -66, -17, -44, -72, -77, -71, 26, -69, -2, -36, -58, 21; /M: SY='F'; M= -23, -72, -81, -80, 67, 30, -76, 55, -76, -13, -46, -71, -77, -77, -77, -66, -60, 41, -64, -46; /M: SY='V'; M= -58, -69, -84, -78, -49, -86, -80, 47, -76, 40, -37, -79, -79, -75, -77, -70, -55, 78, -80, -58; /M: SY='N'; M= -60, -69, -68, -72, 33, -73, -67, 29, -68, 32, -44, 57, -78, -68, -71, -7, -54, 53, -75, -54; /M: SY='N'; M= -56, -65, -45, -58, -73, -13, -53, -69, -6, -75, -66, 95, -66, -54, -58, -3, 74, -65, -90, -69; /M: SY='K'; M= -14, -77, -57, -43, -78, -69, -58, -79, 100, -77, -65, -50, -65, -40, 44, -56, -58, -73, -73, -65; /M: SY='W'; M= 21, -75, -85, -76, 80, -74, -75, -7, -73, 14, -51, -78, 1, -75, -75, -68, -65, -5, 111, -35; /M: SY='D'; M= -68, -81, 114, -33, -85, -65, 57, -86, -55, -82, -79, -36, -67, -53, -62, -56, -58, -83,-103, -65; /M: SY='Q'; M= 8, -71, -55, -52, -67, -63, 27, -61, 19, 23, 12, 59, -70, 65, -52, 1, 0, -62, -79, -61; /M: SY='I'; M= 32, -69, -70, -63, -61, -69, -67, 34, -5, 10, 17, -63, -71, 15, 20, 16, 0, 26, -77, -62; /M: SY='D'; M= 34, -73, 49, 24, -69, -67, -62, -6, -52, 3, -57, -57, -5, -54, 39, -3, -56, 11, -81, -66; /I: I=-42; MD=-106; /M: SY='K'; M= -15, -83, 26, 40, -86, -74, -65, -85, 43, -84, -76, -57, 7, -52, 26, 17, 3, -79, -88, -76; D=-42; /I: I=-42; MI=-106; MD=-106; IM=-106; DM=-106; /M: SY='N'; M= -64, -82, -55, 43, -84, 43, -64, -84, 18, -23, -74, 48, -73, 12, -61, -7, -65, -82, -86, -78; D=-42; /I: I=-42; DM=-106; /M: SY='T'; M= -59, -71, 7, 22, 43, -71, -63, -56, -60, 25, -54, -58, 28, 8, -65, 17, 58, -57, -72, -54; /M: SY='Q'; M= -9, -77, 25, 44, -77, -67, -56, -11, -4, -31, -63, -53, 10, 59, 39, 31, -56, -67, -79, -66; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='C'; M= -17, 74, 42, -55, -70, -65, -57, -70, 13, -67, 54, 49, -73, 15, -59, 20, -10, -68, -83, 10; D=-36; /I: I=-36; DM=-90; /M: SY='P'; M= 29, -72, -65, -2, -65, -7, -65, -6, 18, 18, 22, -62, 35, -56, 20, -5, -1, -12, -76, -65; /M: SY='R'; M= -16, -76, 40, 45, -74, -16, -56, -68, -44, -66, 54, -53, -67, 17, 59, 20, -57, -16, -80, -65; /M: SY='D'; M= -18, -77, 84, -1, -76, -66, -55, -73, 0, 0, -66, -46, -69, 17, 44, 13, -57, -71, -85, -66; /M: SY='V'; M= 11, -68, -82, -76, -54, -80, -84, 55, -74, -40, -42, -76, -76, -75, -77, -64, -53, 85, -83, -61; /I: I=-31; MD=-79; /M: SY='Q'; M= -74, -88, -3, 19, -84, -80, 22, -81, 20, -1, -71, 34, -80, 37, 25, -19, -70, -82, -92, -74; D=-31; /I: I=-31; MD=-79; /M: SY='K'; M= 6, -88, 2, 21, -88, -81, -70, -23, 43, -80, -74, -66, -78, 16, 39, -68, -70, -15, -89, -78; D=-31; /I: I=-31; MI=0; MD=-79; IM=0; DM=-79; /M: SY='Q'; M= -80, -91, -6, -75, 30, -92, -80, -5, -79, 14, -65, -79, -92, 52, -80, -15, -2, -23, -87, -68; D=-31; /I: I=-31; DM=-79; /M: SY='H'; M= -18, -73, -71, -9, -43, -79, 70, 2, -69, 57, -39, -69, -78, -62, -67, -67, -62, 15, -65, 59; /M: SY='S'; M= -52, -71, -58, 18, -70, 47, -59, -66, -57, 1, 51, 2, -67, 12, -5, 59, -53, -65, -77, -66; /M: SY='N'; M= 27, -72, -51, 34, -75, 29, -59, -75, -56, -77, -68, 52, 49, -54, -64, 22, 0, -70, -77, -1; /M: SY='R'; M= -60, -76, -63, -6, -65, 26, -61, -63, 31, 17, -56, -58, 36, 8, 40, -6, 2, -22, -72, 9; /M: SY='C'; M= -12, 70, -70, -7, 32, -18, -68, -6, -13, 28, 28, -63, -73, -65, -68, -1, 38, -10, -74, -56; /M: SY='W'; M= -63, -75, -76, -73, 47, -18, -66, 20, -66, 1, 29, 3, 1, -67, -3, -8, -61, 25, 86, 37; /M: SY='P'; M= 24, -76, -57, -6, -79, -6, 49, -76, 20, -76, -66, 10, 67, 13, 18, 22, -55, -72, -80, -67; /M: SY='L'; M= -10, -72, 27, -61, 28, -10, -61, -49, -10, 54, 30, 22, -76, 8, -4, -63, -60, -54, -71, -54; /M: SY='C'; M= 25, 33, 1, -57, -67, -10, -65, -7, 33, 16, -56, -58, 12, -56, 32, -10, 19, -57, -78, -66; /I: I=-8; MD=-21; /M: SY='K'; M= 10, -73, -67, -58, -70, -72, -67, 14, 53, -60, 17, -60, -70, 12, 19, -5, 24, 28, -80, -66; D=-8; /I: I=-8; MD=-21; /M: SY='D'; M= -68, -86, 52, -66, 6, 39, -75, -76, -74, -21, -75, -62, 28, -74, -81, -8, 0, -16, -89, -74; D=-8; /I: I=-8; MD=-21; /M: SY='F'; M= -81, -89, -85, -7, 65, -13, -71, -12, -82, 4, -61, -84, 8, -81, -83, -80, -77, -67, -60, 61; D=-8; /I: I=-8; MD=-21; /M: SY='F'; M= -78, -87, -92, -85, 41, -95, -80, -12, -84, 4, 19, -86, -2, 11, -84, -80, 1, 24, -77, 18; D=-8; /I: I=-8; MD=-21; /M: SY='H'; M= -74, -91, -84, -83, 5, 33, 52, 11, -81, -73, -70, -74, -87, 12, -83, -73, 0, 8, 46, -67; D=-8; /I: I=-8; MD=-21; /M: SY='V'; M= 7, -83, -3, -83, 27, -87, -88, -2, -85, -15, -64, -81, -89, -85, -88, -13, -4, 42, -89, -68; D=-8; /I: I=-8; MD=-21; /M: SY='V'; M= -22, -86, -91, -84, 6, -90, -84, -10, -15, 14, -61, -86, 10, -82, -83, -11, -71, 37, -83, 15; D=-8; /I: I=-8; MD=-21; /M: SY='P'; M= -69, 23, -78, -75, -89, -78, -82, -75, -77, -86, -80, -5, 69, -76, -85, 44, -8, 9,-100, -88; D=-8; /I: I=-8; MD=-21; /M: SY='T'; M= -76, 31, -79, -75, 1, -88, -80, -14, 27, -26, -71, 4, -86, -73, 16, -69, 41, -10, -92, -74; D=-8; /I: I=-8; MD=-21; /M: SY='G'; M= 11, -86, -6, -73, -1, 24, 24, -90, -11, -87, -81, 2, -84, -71, -1, 14, -10, -84, -92, -76; D=-8; /I: I=-8; MD=-21; /M: SY='Q'; M= -76, -98, -76, -63,-101, -19, -73, -95, -2, -93, -81, -70, -2, 79, 19, -6, -5, -93, -94, -83; D=-8; /I: I=-8; MD=-21; /M: SY='S'; M= -80, -99, -6, -6, -99, -90, -84, -89, -17, -91, 24, -78, -93, 5, 1, 37, -76, -18,-107, -90; D=-8; /I: I=-8; MI=0; MD=-21; IM=0; DM=-21; /M: SY='N'; M= -82,-100, -81, -13, -96, 25, -89, 22, -6, -90, -86, 28, -94, -82, -87, -11, -82, -81,-104, -94; D=-8; /I: I=-8; DM=-21; /M: SY='Q'; M= -76, -92, 4, -15, -94, -83, -77, -83, -75, -30, -82, 32, -90, 35, -80, 29, -10, -14,-106, -87; D=-8; /I: I=-8; DM=-21; /M: SY='P'; M= -14, -91, 40, -7, -92, 23, -72, -10, -69, -87, -80, 25, 51, 15, -77, -65, -70, -81, -94, -84; D=-8; /I: I=-8; DM=-21; /M: SY='E'; M= -62, -75, 1, 52, -70, -18, 24, -6, 18, 6, -58, 48, -67, 10, 26, -55, 1, -64, -81, -64; /M: SY='L'; M= 8, -72, 4, 31, 6, -70, -60, 22, -13, 41, -48, 30, -72, -57, -64, -2, -57, -50, -71, 11; /M: SY='P'; M= -58, -74, -3, 20, -4, -62, 24, -75, 31, -76, -67, 50, 53, 19, -52, 43, -9, -73, -80, -64; /M: SY='Q'; M= -10, -70, -66, -64, -53, -71, -61, 18, -60, 28, -46, 31, -74, 34, -5, -3, 23, 30, -71, 34; /M: SY='C'; M= 9, 60, 6, 28, -74, -9, 22, -15, -55, -70, -64, 10, 36, -55, 17, 16, 4, -13, -84, -69; /M: SY='E'; M= -18, -74, 10, 69, -77, -67, -55, -68, -45, -71, -65, 29, -64, 38, 24, 20, -4, 8, -82, -68; /M: SY='A'; M= 45, -71, -1, 22, 0, -64, -62, 17, -58, -61, -58, -59, 12, 42, -62, 16, 2, -6, -72, 13; /M: SY='W'; M= -63, 28, 4, -55, -63, -71, 19, -57, 19, 34, -52, 30, 11, 41, 19, -10, -59, -9, 47, -59; /M: SY='Q'; M= 6, -79, 28, 35, -79, -69, -53, -75, -38, -71, 10, -52, -67, 73, 69, -53, -2, -71, -78, -65; /M: SY='W'; M= 29, -72, -3, -4, 26, -71, -65, -47, -57, -14, -53, -66, -74, 34, 23, -59, -59, 48, 57, 19; /M: SY='Y'; M= -62, -77, 1, 64, -54, -73, 25, -62, -52, -60, 49, 7, -67, 37, -56, -57, 4, -9, -62, 71; /M: SY='E'; M= -57, -75, 31, 55, -76, 10, -58, -7, 29, -70, -65, 6, -64, 16, -5, 17, -4, -8, -81, -68; /M: SY='D'; M= -18, -76, 55, 45, -74, -10, -58, -13, 16, -2, -63, -51, -66, 13, 24, 21, -56, -66, -81, -66; /M: SY='F'; M= -62, -71, -69, -71, 73, -71, -63, 43, -64, -21, -51, 34, -75, -66, -5, 33, -3, -9, -61, 12; /M: SY='F'; M= 9, -72, -82, -76, 96, -78, -67, 34, -12, 7, -47, -73, -80, -76, -70, -68, -63, -46, -50, 20; /M: SY='W'; M= -65, -80, -65, -6, 28, -73, 30, -63, 14, 15, -55, -62, 3, 56, 35, -7, -63, -66, 86, 16; /M: SY='D'; M= 11, -71, 40, 20, 5, -64, 22, -58, -58, -19, 26, 32, 12, -55, -64, 29, -9, 11, -81, -61; /I: I=-36; MD=-90; /M: SY='H'; M= -10, -77, 25, 48, -77, -66, 86, -78, -53, -26, -64, 3, -67, 44, -56, 33, -57, -75, -88, -60; D=-36; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='P'; M= -66, -82, 1, 35, -78, -72, -58, -77, 43, -19, -67, 34, 55, -48, 53, -60, -61, -75, -81, -71; D=-36; /I: I=-36; DM=-90; /M: SY='Y'; M= -20, -75, 3, -3, -57, -17, -60, -8, 16, 19, -52, -61, 3, 17, 26, -4, -58, 23, -69, 40; /M: SY='F'; M= -68, -73, -2, -71, 58, -81, -64, -42, -4, 54, -42, -74, -81, -69, -68, -71, -63, 12, 58, 51; /M: SY='R'; M= -58, -75, 7, 19, -4, -12, -59, -6, 20, -20, 23, -54, 12, -50, 50, 40, -4, -62, -76, -62; /M: SY='H'; M= -15, -75, 44, -2, -71, 7, 68, -12, 0, -5, -61, 11, 10, -53, 0, 18, -6, -66, -84, -61; /M: SY='C'; M= 24, 32, 3, -62, 5, 26, -64, -18, -1, 0, 15, 1, -70, -59, -3, 32, 4, -59, -76, -62; /I: I=-19; MD=-47; /M: SY='D'; M= -23, 22, 37, -61, 25, -75, 31, -4, -8, 28, 29, 8, 1, -63, -2, -66, -63, -58, -72, 20; D=-19; /I: I=-19; MD=-47; /M: SY='Q'; M= -12, -79, 36, 44, -71, -74, -59, -64, -53, 29, -57, -58, 4, 63, 2, -59, -2, -65, -81, -66; D=-19; /I: I=-19; MD=-47; /M: SY='E'; M= -70, -88, 19, 55, -89, -81, -66, -83, 45, -83, -77, -61, -73, 13, 24, -12, -67, -14, -89, -77; D=-19; /I: I=-19; MD=-47; /M: SY='N'; M= 23, -83, -67, -10, -81, -17, -71, -22, -12, 2, -69, 48, 2, 10, -71, -5, -66, -72, -91, -79; D=-19; /I: I=-19; MD=-47; /M: SY='R'; M= -18,-103, -82, -7, 3, -95, 28, -99, 13, -93, -85, -79, -93, 35, 38, -81, -87, -96, -96, -78; D=-19; /I: I=-19; MI=0; MD=-47; IM=0; DM=-47; /M: SY='I'; M= 8, -79, -83, -78, -69, -16, -82, 42, -77, -20, 16, -75, -81, 14, -80, -6, 0, 37, -88, -71; D=-19; /I: I=-19; DM=-47; /M: SY='G'; M= -55, -76, 27, 0, -79, 67, -67, -79, 20, -24, -71, -51, -68, -59, -63, 15, 23, -75, -81, -73; D=-19; /I: I=-19; DM=-47; /M: SY='F'; M= -64, -73, -76, -3, 43, -84, -73, 41, -69, 23, 24, -72, -76, -70, -8, -66, 34, 28, -72, -52; D=-19; /I: I=-19; DM=-47; /M: SY='P'; M= 10, -79, -2, 0, -73, 11, -64, 15, 17, -71, -64, -59, 53, 37, -60, 20, -58, -64, -75, 9; D=-19; /I: I=-19; DM=-47; /M: SY='K'; M= 24, 24, -57, -4, -76, -62, 51, -71, 52, -74, -65, 11, 51, -51, -50, 32, -53, -23, -81, -66; /M: SY='L'; M= -14, -69, -79, -74, 12, -80, 28, 4, -74, 73, -35, -75, -80, -69, -73, -11, -59, 16, -72, -51; /M: SY='R'; M= 1, -76, -65, -6, 6, -15, -57, -63, -40, 5, -56, -60, -74, 6, 84, -3, -61, -16, -69, 14; /M: SY='H'; M= -64, -79, 38, 47, -69, -74, 58, -64, -8, 18, -56, -54, -68, 49, 41, -59, -62, -14, -81, -60; /M: SY='W'; M= 45, -71, 5, -58, 27, -63, -59, -66, 25, -64, -61, -58, -70, -57, 0, 18, 17, -61, 59, 56; /M: SY='L'; M= 11, -70, -73, 19, -49, -79, -70, 24, -70, 69, -36, -76, -76, -65, -72, -68, -60, 17, -74, -58; /M: SY='E'; M= 7, -72, 7, 46, -73, -11, -57, -15, -3, -21, 11, 31, -65, 16, -2, 37, -3, -63, -80, -67; /M: SY='Q'; M= -58, -75, 9, 38, -78, -8, 27, -76, 18, -33, -65, 57, -66, 67, -49, 28, -54, -74, -82, -65; /M: SY='I'; M= -63, 33, 3, 15, 31, 9, -68, 40, -66, 30, -47, -66, 5, 29, -69, -64, -61, -2, -72, -56; /M: SY='W'; M= -63, -71, -78, -70, 31, -81, -71, 21, -70, 53, -40, -72, -77, 29, -70, -65, 26, 29, 57, -49; /M: SY='W'; M= -15, -79, -60, 36, 7, -10, 50, -13, -54, -23, -61, 8, -70, 9, 21, -17, -10, -68, 114, -48; /M: SY='K'; M= 8, -74, 45, -2, -77, -63, -56, -16, 61, -73, -66, 32, -66, 16, 9, 10, -3, -67, -81, -67; /M: SY='R'; M= -61, -75, 4, -55, -64, -71, 46, -4, 35, 18, 47, -55, -71, -49, 59, 31, -57, -59, -78, -58; /M: SY='Y'; M= -66, -76, -1, -6, -41, -80, -57, 39, -4, 32, 46, -69, -76, -60, -4, -68, -61, -2, -57, 77; /M: SY='Q'; M= -22, 24, -58, 2, 29, -12, -57, -69, 31, -16, -60, 10, -69, 64, 24, 30, -56, -68, -71, -57; /I: I=-36; MD=-90; /M: SY='E'; M= -66, -80, 30, 53, -77, -75, -61, -7, -7, -3, -65, 31, -70, 36, -11, -59, 23, -67, -87, -71; D=-36; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='S'; M= 10, 16, -58, -61, -67, -10, -60, -5, -1, 12, -58, 48, -69, -55, -5, 60, 2, -58, -81, -66; /M: SY='L'; M= -18, 32, -77, -13, 44, -81, -71, 37, -71, 46, -40, -74, -78, 13, -72, -68, -60, 33, -69, -50; /M: SY='P'; M= -10, -87, -58, 36, -85, -68, -66, -75, -3, -81, -70, -68, 114, -57, -66, -60, -59, -76, -79, -80; /I: E1=0; IE=-380; DE=-380;» more |
Post-processing [info]
| COMPETES_HIT_WITH | PS51705; PS51706; PS51709; PS51710; PS51711; PS51712; PS51713; PS51714; PS51715; PS51716; PS51717; PS51719; PS51720; PS51721; PS51722 |
Numerical results [info]
| Total number of hits | 130 in 130 different sequences |
| Number of true positive hits | 130 in 130 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 2 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 98.48 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | Dynamin-type G |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
130 sequences
ARC5_ARATH (Q84N64), BDLP_NOSP7 (B2IZD3), CRFC_ECOLI (P0DM85), CRFC_ECOLX (P0DM86), DLP1_CAMJJ (A0A0H3PJL7), DLPA_DICDI (Q55F94), DLPB_DICDI (Q54MH8), DLPC_DICDI (Q55AX0), DNM1L_BOVIN (Q2KIA5), DNM1L_CAEEL (Q8WQC9), DNM1L_DANRE (Q7SXN5), DNM1L_HUMAN (O00429), DNM1L_MOUSE (Q8K1M6), DNM1L_RAT (O35303), DNM1_SCHPO (Q09748), DNM1_YEAST (P54861), DRP1A_ARATH (P42697), DRP1B_ARATH (Q84XF3), DRP1C_ARATH (Q8LF21), DRP1D_ARATH (Q8S3C9), DRP1E_ARATH (Q9FNX5), DRP2A_ARATH (Q9SE83), DRP2B_ARATH (Q9LQ55), DRP3A_ARATH (Q8S944), DRP3B_ARATH (Q8LFT2), DRP4A_ARATH (Q9ZP56), DRP4C_ARATH (Q9ZP55), DRP5A_ARATH (F4HPR5), DYN1_BOVIN (Q08DF4), DYN1_CAEEL (P39055), DYN1_HUMAN (Q05193), DYN1_MOUSE (P39053), DYN1_RAT(P21575), DYN2_BOVIN (A6H7I5), DYN2_HUMAN (P50570), DYN2_MOUSE (P39054), DYN2_RAT(P39052), DYN3_HUMAN (Q9UQ16), DYN3_MOUSE (Q8BZ98), DYN3_RAT(Q08877), DYNA_DICDI (Q94464), DYNB_DICDI (Q9U1M9), DYN_DROME (P27619), EHD1_ARATH (Q94CF0), EHD1_BOVIN (Q5E9R3), EHD1_HUMAN (Q9H4M9), EHD1_MOUSE (Q9WVK4), EHD1_PONAB (Q5RBP4), EHD1_RAT(Q641Z6), EHD2_ARATH (B3LF48), EHD2_HUMAN (Q9NZN4), EHD2_MOUSE (Q8BH64), EHD2_RAT(Q4V8H8), EHD3_HUMAN (Q9NZN3), EHD3_MOUSE (Q9QXY6), EHD3_RAT(Q8R491), EHD4_HUMAN (Q9H223), EHD4_MOUSE (Q9EQP2), FZO1_CAEEL (Q23424), FZO1_SCHPO (Q9USY7), FZO1_YEAST (P38297), FZO_DROME (O18412), FZO_DROSI (Q9N6P4), MARF_DROME (Q7YU24), MFN1_HUMAN (Q8IWA4), MFN1_MOUSE (Q811U4), MFN1_RAT(Q8R4Z9), MFN2_HUMAN (O95140), MFN2_MOUSE (Q80U63), MFN2_RAT(Q8R500), MGM1_CHATD (G0SGC7), MGM1_YEAST (P32266), MSP1_SCHPO (P87320), MX1B_MOUSE (P09922), MX1_BOVIN (P79135), MX1_CANLF (Q9N0Y3), MX1_EUMJU (Q4ADG8), MX1_HORSE (Q28379), MX1_HUMAN (P20591), MX1_ICTPU (Q7T2P0), MX1_MACMU (A1E2I4), MX1_MOUSE (Q3UD61), MX1_ONCMY (Q91192), MX1_OTABY (Q4ADG7), MX1_PHOVI (Q4ADG6), MX1_PIG (P27594), MX1_PONAB (Q5R5G3), MX1_RAT (P18588), MX1_SHEEP (P33237), MX2_BOVIN (Q9BDI7), MX2_BUBBU (A0MWD1), MX2_CANLF (Q9N0Y2), MX2_HUMAN (P20592), MX2_ICTPU (Q4U4N4), MX2_MACMU (A1E2I5), MX2_MOUSE (Q9WVP9), MX2_ONCMY (Q91196), MX2_PIG (A7VK00), MX2_RAT (P18589), MX2_SHEEP (Q5I2P5), MX3_ONCMY (Q91197), MX3_RAT (P18590), MXA_DANRE (Q8JH68), MXB_DANRE (Q800G8), MXC_DANRE (Q6DKF0), MXE_DANRE (Q800G5), MX_ANAPL(P33238), MX_CHICK(Q90597), MX_CTEID(Q6TKS7), MX_DICLA(Q2KTC2), MX_EPICO(Q6PW23), MX_LARCR(Q000A9), MX_PERFL(P20593), MX_SINCH(Q6TN15), MX_SOLSE(Q5U752), OPA1_CHICK (Q5F499), OPA1_DANRE (Q5U3A7), OPA1_HUMAN (O60313), OPA1_MOUSE (P58281), OPA1_ONCMA (O93248), OPA1_PONAB (Q5RAM3), OPA1_RAT(Q2TA68), SDL5A_SOYBN (Q39828), SDLCA_SOYBN (Q39821), SRCA_CHICK (Q90577), SRCA_HUMAN (Q86TD4), SRCA_MOUSE (Q7TQ48), SRCA_RABIT (P13666), VPS1_SCHPO (Q9URZ5), VPS1_YEAST (P21576)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
2 sequences
DLP2_CAMJJ (A0A0H3PJK4), DYNA_BACSU (P54159) |
| PDB [Detailed view] |
80 PDB
1JWY; 1JX2; 2AKA; 2J68; 2J69; 2QPT; 2W6D; 2X2E; 2X2F; 3L43; 3SNH; 3SZR; 3T34; 3T35; 3W6N; 3W6O; 3W6P; 3ZVR; 3ZYC; 3ZYS; 4BEJ; 4CID; 4H1U; 4H1V; 4P4S; 4P4T; 4P4U; 4UUD; 4UUK; 4WHJ; 5A3F; 5D3Q; 5GNR; 5GNS; 5GNT; 5GNU; 5GO4; 5GOE; 5GOF; 5GOM; 5GTM; 5MTV; 5MVF; 5OWV; 5OXF; 5UOT; 5WP9; 5YEW; 6DLU; 6DLV; 6JFK; 6JFL; 6JFM; 6JSJ; 6JTG; 6QL4; 6RZT; 6RZU; 6RZV; 6RZW; 6S9A; 7AX3; 7SOX; 8CT1; 8CT9; 8EEW; 8EF7; 8EFF; 8EFR; 8EFS; 8EFT; 8SXZ; 8SZ4; 8SZ7; 8SZ8; 8T0K; 8T0R; 8T1H; 8TYM; 8TYN » more |