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PROSITE entry PS51705


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PURL: https://purl.expasy.org/prosite/signature/PS51705

Direct ScanProsite submission
General information about the entry

Entry name [info] G_HFLX
Accession [info] PS51705
Entry type [info] MATRIX
Date [info] 01-FEB-2014 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51705
Associated ProRule [info] PRU01042

Name and characterization of the entry

Description [info] HflX-type guanine nucleotide-binding (G) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=167;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=162;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.8205030; R2=0.0077951; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=31671.6699219; R2=3.9186404; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=1371; H_SCORE=37044; N_SCORE=13.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=473; H_SCORE=33525; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-128; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
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Post-processing [info]

COMPETES_HIT_WITH PS51706; PS51709; PS51710; PS51711; PS51712; PS51713; PS51714; PS51715; PS51716; PS51717; PS51718; PS51719; PS51720; PS51721; PS51722

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 26 in 26 different sequences
Number of true positive hits 26 in 26 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] Hflx-type G
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
26 sequences

GTPB6_HUMAN (O43824), GTPB6_MOUSE (Q3U6U5), GTPB6_XENLA (Q6DCC6), 
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PDB
[Detailed view]
14 PDB

2QTF; 2QTH; 3KXI; 3KXK; 3KXL; 5ADY; 5ZZM; 7OF2; 7OF4; 7OF6; 7YLA; 8G31;
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