PROSITE entry PS51704

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51704
Entry name [info]	GP_PDE
Accession [info]	PS51704
Entry type [info]	MATRIX
Date [info]	01-FEB-2014 CREATED; 01-FEB-2014 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51704
Associated ProRule [info]	PRU01041

Name and characterization of the entry

Description [info]

GP-PDE domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=253;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=248;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3443367; R2=0.0081201; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=759; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=512; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-28; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='P';  M= -27, -77, -69, -60,  -5, -72, -68,  37, -15, -28,   2, -65,  74,  23,  10,   9,   0,  15, -76, -63;
/M: SY='M';  M= -25, -72, -70, -23,  14,  18, -65,  28,  -1,  33,  43, -64, -73, -61,  20, -20,  14, -48, -69,  -7;
/M: SY='I';  M=  -5, -70,  -1, -68, -54, -76,  11,  51, -22,  36, -42,  23, -75, -66, -70, -63, -15,  42, -80, -59;
/M: SY='I';  M= -22, -71, -76, -75,  31, -25, -72,  65, -72, -18, -45, -11, -75, -70, -74,  22, -54,  45, -68,  17;
/M: SY='A';  M=  72, -67,  -2,  21, -78,  27, -64, -72, -58, -72, -66,  -4, -65,  -3, -64,  10, -15, -61, -78, -71;
/M: SY='H';  M= -66, -79, -57, -55, -64, -70, 126, -78, -10, -69, -57, -48,  26, -49,  22, -16,  13, -77, -83,  28;
/M: SY='R';  M= -65, -81, -14, -55, -62,   7, -51, -78, -33, -72, -63,   0, -75, -46,  99, -58, -19, -74, -66,  52;
/M: SY='G';  M=  11, -76, -65, -11, -75,  87, -71, -83, -64, -80, -72, -55, -68, -63, -19, -51, -14, -78,  82, -67;
/M: SY='A';  M=  57, -69, -66, -62,  18,  33, -62, -65,  37, -16, -59, -59, -70, -58, -57,  -8, -58, -61, -63,  40;
/M: SY='S';  M=  17, -69, -61, -59, -10,  -5,  21, -70,   1, -37, -65, -52,  29, -54, -61,  77,  -1, -65,  46, -61;
/M: SY='G';  M=  26, -71, -63, -10, -10,  61,   8, -68,  -1, -32,  46, -54, -67, -58,  -5, -13,  23, -64, -75, -64;
/M: SY='Y';  M= -26, -74,  31,   8, -55, -11, -57,   5,   1,  21,  12, -13, -71,  15, -17,  14, -57, -13, -67,  49;
/M: SY='Y';  M=  43, -69, -68, -64,  16, -26, -59, -50, -60,   8, -52,  13, -74,  10,   8,  -3, -56,  25, -63,  54;
/I:         I=-28; MD=-70;
/M: SY='P';  M= -68, -89, -70, -59,   0, -28,  20, -71, -64, -13, -65, -72, 111,  -8, -15, -66, -63, -75, -78, -71; D=-28;
/I:         I=-28; MI=0; MD=-70; IM=0; DM=-70;
/M: SY='E';  M= -61, -81,  45, 100, -84, -21, -54, -85,  -4, -78, -74, -52, -58, -38, -52, -56, -60, -78, -82, -73;
/M: SY='N';  M= -62,  21, -43, -58, -71, -56,  74, -72, -52, -21, -63, 106, -72, -52, -58,  -4,   1, -73, -95, -62;
/M: SY='T';  M= -52, -62, -57, -61, -67, -65, -64, -59, -57, -62,  26,   9, -61, -60, -65,  18, 106, -52, -87, -65;
/M: SY='M';  M= -18, -70, -10, -68,  -4, -78, -68,  44,   3,  44,  61, -68, -73, -65, -67, -64,  24,   7, -74, -55;
/M: SY='M';  M=  38, -70,  -2,   3, -58, -66,  13, -53, -63,  39,  47, -63,  24,  -4, -65,  18, -56, -54, -73,   8;
/M: SY='A';  M=  77, -62, -62, -59, -75, -50, -65, -68, -60, -70, -64, -54, -65, -55, -65,  68,   2, -57, -79, -69;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='F';  M= -70, -73, -81, -76,  93, -82, -63,  21,   3,  16, -45, -74, -82, -74, -67, -71, -64, -15, -47,  58;
/M: SY='Q';  M= -22, -75,  34,  36, -73, -70, -58,  -2, -46, -64, -60,  -4, -67,  52,  43,  -6,  17,  24, -82, -65;
/M: SY='K';  M= -23, -71,  -3, -53,   1, -68,  13, -58,  47,  11,  32,  35, -68,  40, -50, -53,  43, -24, -77, -58;
/M: SY='A';  M=  86, -63, -66, -62, -75,  15, -69, -64, -63, -68, -62, -59, -67, -60, -68,  16, -16, -10, -77, -71;
/M: SY='W';  M=  36, -69, -71, -64,  17, -66, -65,   4, -10,  -9,  13, -64, -72,  20, -64,  32, -54,  32,  47,  24;
/M: SY='K';  M=  31, -72, -10,  36, -78, -61, -58, -72,  60, -73, -65,   3, -64,  35, -44,  35, -52, -24, -78, -68;
/M: SY='Q';  M=  18,   5,  -6, -17,  -8, -66,  33, -16, -58,  19,  29,  35, -72,  50, -60,  -9,  -3, -57, -72,  24;
/M: SY='G';  M= -52,  16, -10, -63, -81,  82, -63, -85,   2, -82, -72,  24, -68,   6, -12,  17, -60, -79, -77, -74;
/M: SY='A';  M=  77, -65, -70, -65,  14,  14,   6, -10, -66, -28, -56, -63, -69, -64, -70, -48, -11,  11, -73, -61;
/M: SY='D';  M= -11, -77,  98,  -1, -78, -63,   9, -80, -18, -79, -75, -41,   5, -53, -61,  21, -13, -76, -89,  -2;
/I:         I=-42; MI=0; MD=-106; IM=0; DM=-106;
/M: SY='Y';  M= -17,  12, -74, -75,  48,  48, -62, -50, -70, -23,  47, -65, -75, -69, -72, -59,  -6,  25, -58,  60;
/M: SY='I';  M= -61, -71, -85, -79, -11, -86, -78,  67, -77,  39,  24, -78, -78, -74, -77, -72, -57,  58, -75, -55;
/M: SY='E';  M= -60, -82,   0,  91, -74, -72, -58, -75, -46, -73, -69, -58, -61,  45, -54,  -4, -61, -18,  91, -62;
/M: SY='C';  M= -25,  64, -77, -71,  47, -78, -69,  14, -70,  39,  22, -69, -77,  23, -71, -62,  29,  14, -70, -50;
/M: SY='D';  M= -66, -78, 110, -36, -75, -65, -54, -77, -56, -22, -74, -39, -68, -55, -64, -12,  -4, -75, -90,  12;
/M: SY='V';  M=   0,  43, -82, -76, -54, -81, -81,  24, -75,  17, -42, -77, -79, -75, -76, -65, -54,  83, -84, -62;
/M: SY='Q';  M= -61,  31, -58, -12, -77, -71,  64, -68, -12, -66,   2, -52, -69,  99,  40, -54, -14,  -2, -79, -58;
/M: SY='M';  M= -13, -70, -81, -74,  20, -80,  25,  10, -73,  61,  82, -75, -78, -67, -71, -71, -61,   6, -71, -49;
/M: SY='T';  M= -49, -62, -58, -60, -67, -63, -65, -60, -58, -18, -60, -47, -61, -58, -65,  57,  99, -53, -85, -65;
/M: SY='K';  M= -17, -73, -56, -47, -72, -64, -57, -74,  88, -35, -64,  11, -65, -44,  15,  37, -53, -70, -73,  -4;
/M: SY='D';  M= -68, -81, 119, -31, -88, -64, -53, -86, -55, -85, -84, -35, -67, -54, -63, -56, -57, -83,-103, -70;
/M: SY='G';  M= -13, -76,  -7,  36, -78,  71, -61, -79,  10, -38,   5,  15, -67, -53,  20, -53, -62, -75, -77, -71;
/M: SY='V';  M= -57, -72, -65,   9, -62, -77,   7,  27, -19, -48,  39,  -6, -71,  57, -22, -59,   2,  63, -81, -60;
/M: SY='P';  M= -24, -77, -76, -68, -59, -16, -74,  38, -71,  31, -46, -75,  83, -70, -76, -66, -58,  34, -77, -66;
/M: SY='V';  M= -58,  12, -84, -79,  48, -85, -81,  38, -76, -10, -42, -78, -80, -79, -77, -69, -55,  82, -73, -50;
/M: SY='V';  M= -11,  64, -83, -77, -51, -82, -78,  24, -76,  43, -40, -77, -80, -75, -77, -68, -56,  68, -81, -61;
/M: SY='M';  M=   5, -71, -73, -71,   6, -71, -59,  14, -67,  26,  68, -13, -75, -63, -68,  21, -12, -18,  52,  61;
/M: SY='H';  M= -67, -81, -57, -54, -69, -70, 132, -79, -56, -25, -55, -48,  49,   3,  -3, -13, -64, -79, -93, -45;
/M: SY='D';  M= -64, -80, 104, -36, -85, -64, -55, -83,  14, -83, -78, -40,  28, -52,   0,   8, -56, -80, -94, -70;
/M: SY='W';  M= -63, -77,  27,  43,  36, -72,  40, -15, -14, -32, -60,  -8,   9, -53,   7,   6, -14, -14,  52,  10;
/M: SY='N';  M= -61, -72,  28, -54, -63, -66,  14,   1,  11, -37, -60,  61, -69, -52,  39,  -7,  45, -62, -76,  35;
/M: SY='L';  M= -61,  10, -82, -76,  -4, -83, -71,   3, -74,  62,  49, -76, -79, -71, -74, -69,   7,  48, -75, -54;
/M: SY='D';  M=  -3,   9,  60,  30, -74,  -1, -56, -71,   7, -11,  20,  44, -68, -50,   8,   2, -56, -69, -84, -68;
/M: SY='R';  M= -63,  28, -58,  19,   4, -74, -57, -66, -37, -34, -61,  24, -73, -48,  89, -57,  18,  -2, -77, -61;
/M: SY='T';  M=   4, -66,  -2,  -8, -68, -12, -64, -57,  -3, -22,  33, -52, -64,   1, -61,  22,  76,   0, -82, -65;
/M: SY='T';  M= -18, -66, -59, -63, -13,  30, -65, -63, -60, -66,   4,  24, -65, -60, -66,  42,  77, -20,  30, -63;
/M: SY='N';  M=   1, -70,  49, -54, -73,  13, -57,  -9,   3, -31, -64,  70, -68, -56, -60, -20,  41, -28, -86, -69;
/M: SY='V';  M= -57, -73,  28, -62, -66,  44, -69,  10,  10, -13, -55,  -5, -72, -62,   7, -58,  -4,  50, -81, -66;
/M: SY='N';  M=  35, -70, -12, -16, -63, -64, -60,   9,  -2, -27,   7,  43, -70,  10,   9,   0,  -4,   9,  32,   9;
/I:         I=-15; MD=-37;
/M: SY='G';  M= -68, -89,  31,  18, -84,  47, -73, -81,   4, -42, -78, -63, -79,   2, -71, -27, -72,  -7, -88,  -9; D=-15;
/I:         I=-15; MI=0; MD=-37; IM=0; DM=-37;
/M: SY='P';  M= -67, -78, -11, -15,  42, -73,   3,  -9, -62,   8, -54,  30,  64,  -5, -17, -64, -60,  -5,  33,  45;
/M: SY='V';  M=  10, -67, -17, -69, -56, -74, -75,  10, -70,  22,   6, -69, -11, -69, -73,   2,  -1,  71, -82, -62;
/M: SY='N';  M= -25,  11,  -1, -13,  -4,  -6,  32,  21,  32, -65, -61,  52, -70, -53, -55,  38, -53, -60, -73,  29;
/M: SY='D';  M= -59, -75,  84,  46, -12, -66, -56, -74, -53, -72,   7, -44, -63,   1, -60,  23,  37, -70, -87, -65;
/M: SY='L';  M= -65, -71, -74, -17,  57, -80,   7, -10, -12,  61,  11, -70, -77,   5, -66, -24,   9, -47, -65, -45;
/M: SY='T';  M=  -4, -65,  13, -55, -72, -61,  22, -67,   7, -71, -64,  57, -64, -55, -58,  18,  83, -61, -88, -66;
/M: SY='W';  M= -69, -77, -82, -74,  45, -79, -68, -45,  -7,  48, -45, -13, -81, -69, -68, -73, -66,   6, 117,  43;
/M: SY='E';  M=  20,  15,  34,  58, -76, -25, -60, -12,  -5, -68, -64, -53, -64,  27, -57,  24, -12,  -1, -82, -69;
/M: SY='Q';  M= -60, -81,  41,  62, -18, -69,  11, -78, -44, -73, -65, -49, -63,  96, -49, -13, -14, -76, -78, -62;
/M: SY='L';  M= -65, -70, -85, -78,  43, -85, -71,  24, -77,  70,  25, -80, -82, -74, -75, -75, -61,  25, -67, -47;
/M: SY='Q';  M= -59, -77, -57,   2, -75, -68, -56, -70,  50,  -4, -59, -53,  20,  80,  24,  21,  -2, -69, -75, -64;
/M: SY='K';  M= -60, -74, -17, -14, -70, -27, -59, -65,  49,  12, -57, -53,  -5,  49,  42, -14,  44, -64, -77, -64;
/M: SY='L';  M=   8, -69, -14, -72, -45, -79, -68,  -7, -74,  67, -36, -76, -80, -69, -73, -68, -59,  43, -70,  27;
/I:         I=-4; MD=-10;
/M: SY='N';  M= -63, -74,  46, -15, -73, -65, -55, -10,  20, -31,  10,  75, -71, -52,  26, -18,  -1, -10, -88, -68; D=-4;
/I:         I=-4; MI=0; MD=-10; IM=0; DM=-10;
/M: SY='A';  M=  50, -74, -78, -72,  25, -72,  43, -56, -73,  38, -51, -73, -12, -69, -73, -63, -65, -56, -67,  41; D=-4;
/I:         I=-4; DM=-10;
/M: SY='G';  M=  21, -76,  41, -14, -84,  53, -68, -83,  -9, -83, -76, -52, -70, -61, -69,  29,  10, -75, -86, -77; D=-4;
/I:         I=-4; DM=-10;
/M: SY='W';  M=  15, -78, -60,  15, -76, -67,  35, -21,   0, -74, -67,  25, -72,  29,  17,  33, -19, -24,  47, -65; D=-4;
/I:         I=-4; DM=-10;
/M: SY='W';  M= -62, -79, -68,  18,  -6,  13, -72,  -6, -67, -28, -61,  19, -75, -64, -72,  17, -62,  31, 112,   4; D=-4;
/I:         I=-4; DM=-10;
/M: SY='F';  M= -70, -75, -77, -76,  93, -16,  57,  -8, -73, -51, -55, -67, -81, -75, -72, -19,  15, -59, -52,  43; D=-4;
/I:         I=-4; MI=0; MD=-10; IM=0; DM=-10;
/M: SY='S';  M= -33, -93, -85, -79, -90, -27, -86, -81,  15, -87,  12, -77, -15,  -4, -76,  42, -71,   0,  37, -84; D=-4;
/I:         I=-4; DM=-10;
/M: SY='W';  M= -84,-103,  -7,  30, -11,   1, -82,-101,  17, -97, -91, -78,  16, -70,  14, -81, -85, -98,  31, -84; D=-4;
/I:         I=-4; DM=-10;
/M: SY='S';  M=   7, -90, -76, -25, -97,   2, -79, -96, -23, -97, -88,   9,  -8, -70,  22,  39, -70, -89, -99, -89; D=-4;
/I:         I=-4; DM=-10;
/M: SY='H';  M=  17,  13,  33, -24, -95,  -4,  43, -94, -76, -43, -84,  -4, -14, -75, -11, -72, -79, -89,-105, -85; D=-4;
/I:         I=-4; DM=-10;
/M: SY='H';  M= -18,   7,   3, -15,  30,  -3,  37, -73,  16,  -6, -65, -11,  25,  -1,  17, -22, -66, -73, -79, -61; D=-4;
/I:         I=-4; DM=-10;
/M: SY='R';  M= -25,  14, -66,   4,  -1,   5, -64, -76,  31, -12, -66, -10,  10, -11,  48, -23, -66, -74, -75,   8; D=-4;
/I:         I=-4; DM=-10;
/M: SY='E';  M= -14, -79,   2,  52, -17, -17,  50, -72,   8, -31,   5,   2, -68,  44,  14, -20, -61, -24, -81, -62; D=-4;
/I:         I=-4; DM=-10;
/M: SY='H';  M=  19, -76, -16,   5,  23,  29,  54, -19, -61, -65, -61, -58, -72,   7,  -9,  -2, -16, -23, -67,  43; D=-4;
/I:         I=-4; DM=-10;
/M: SY='Q';  M= -60, -76,  -9,   1, -74,  -7, -61,  -4,  22, -20, -62,  28,  15,  35,  14,  17,  25, -26, -82, -68; D=-4;
/I:         I=-4; DM=-10;
/M: SY='F';  M=  -3,  11,  43, -59,  52,   7,  10, -73, -63, -70, -69,  51, -73, -61, -67,  44, -54, -70, -76, -55; D=-4;
/I:         I=-4; DM=-10;
/M: SY='Q';  M= -25, -77, -55,  44, -70,   5, -57, -31, -13, -16,  18,  -5, -68,  63, -10,  10,  12, -66, -75,  11; D=-4;
/I:         I=-4; DM=-10;
/M: SY='P';  M= -27, -78, -59,   9, -80, -14,  13, -77,  17, -78, -69, -56,  61,   1,  38,  34,  28, -73, -82, -70; D=-4;
/I:         I=-4; DM=-10;
/M: SY='I';  M= -67, -76, -80,   4,  57, -88, -76,  70, -75,   6,  36, -77, -78, -73, -77, -74, -62,  20, -67, -48; D=-4;
/I:         I=-4; DM=-10;
/M: SY='P';  M= -60,  13, -72, -64, -64, -73, -70,  25, -66,  17,   6, -69,  87,  -3, -72,  12, -14,  20, -79, -67;
/M: SY='T';  M=  -1, -65, -59, -14, -67, -65, -65, -59, -58,  -2, -58, -51,  10,   0, -64,  31,  92, -54, -83, -66;
/M: SY='L';  M= -20, -69, -83, -76,  37, -83, -67, -34, -77,  80, -33, -81, -83, -72, -74, -74, -62,  -5, -65,   2;
/M: SY='K';  M=  -6, -75,  17,  50, -72, -70,  25, -19,  61,  -7, -60, -53, -65, -45,   6,   5, -57, -22, -79, -64;
/M: SY='E';  M= -10, -79,  63,  76, -83, -68, -53, -79, -46, -74,   3, -49, -62,  52,  -9,  -3, -58, -74, -83, -69;
/M: SY='V';  M=  35, -68, -79, -74,  32,  -2, -74,  13, -73,  37, -43, -73, -77, -71, -74, -62, -57,  52, -71, -54;
/M: SY='L';  M= -28, -69, -82, -76,  30, -81, -70,   0, -76,  75, -34, -78, -81, -71, -74, -12, -60,  18, -69, -50;
/I:         I=-36; MD=-90;
/M: SY='T';  M= -22, -89, -11,  18, -95, -81,   7, -91, -28, -92, -85,  19, -82,  -2, -76,  16,  42, -85,-105, -85; D=-36;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='W';  M=  -6, -76, -12,  41,   2, -17,  13, -66,  36,  10, -58, -57, -67,  44, -12, -56,  13, -65,  65, -56;
/M: SY='C';  M=  17,  59,  14, -18,  31, -69, -63, -55,   1,  12, -55,  -1, -73, -61,   3,   3,   9,   6, -72,   3;
/M: SY='W';  M=  -8,   8,  -5,  -8, -11, -73, -67,  23,  21,  16, -51, -62,  19, -60, -16, -13,  28,  11,  32,  -8;
/M: SY='P';  M=  -3, -80,  14, -15, -80,  25,  59, -79,  14, -79, -67,  -4,  75,   0,  10, -12, -59, -77, -81, -67;
/M: SY='P';  M= -29, -77, -54,  23, -77,   6,  55, -75,  51, -41, -64,   4,  55,  -1, -11, -11,  11, -73, -80, -65;
/M: SY='N';  M= -59, -75,  28, -56,  13,  44,   8, -74,  20, -30, -67,  55,  33, -56, -15,  12, -56, -74, -77, -63;
/M: SY='M';  M=  22, -69, -76, -68,  17, -73, -66,  30,  17,  -7,  80, -68, -72, -63, -63, -61,  -8,  37, -69,  10;
/M: SY='W';  M= -57,  16, -60, -64, -13,  48,  25, -65,   0, -15,   6,  45, -71,  13, -62, -21,  26, -17,  50,   1;
/M: SY='I';  M= -28, -71, -84, -78,  28, -84, -71,  54, -76,  53,  48, -78, -79, -72, -75, -72, -60,  24, -67,   0;
/M: SY='N';  M= -65, -71,  -9, -16,  32, -69, -55,  24, -62,  22,  29,  76, -76, -61, -66, -60, -56,  -6, -67,  41;
/M: SY='I';  M= -62, -74, -84, -79,  26, -84, -80,  77, -76,  11, -40, -76,  -7, -75, -78, -20, -58,  44,  48, -51;
/M: SY='E';  M= -62, -80,  61,  72, -82, -69,  44, -83,   9, -77, -70,  -3, -62,  38,   4, -11, -58, -78, -85, -66;
/M: SY='I';  M= -60,   5, -77, -19,  -8, -84,  22,  62, -73,  28, -40, -72, -76, -71, -75, -67,   6,  54, -78, -56;
/M: SY='K';  M= -64, -78,   1,  -6, -70, -71, -56, -74,  88, -23, -63,  -3,   3, -43,  36, -58, -59, -72, -71,  15;
/I:         I=-13; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='D';  M=  -5, -97,  13, -29, -94, -11,   9, -10,   7, -87, -83, -77,  -1, -79, -26, -78, -22,  -4,-104, -88; D=-13;
/I:         I=-13; DM=-32;
/M: SY='P';  M= -78, -96, -75,   3, -94, -85, -80, -87,  11, -23, -81, -15,  67,   4, -74,   6, -12, -87, -97, -89; D=-13;
/I:         I=-13; DM=-32;
/M: SY='W';  M= -81,  13,  -9, -80, -16, -38, -84,  -9, -80, -18, -75, -84,  39,   3, -18, -12, -79, -30,  66,   3; D=-13;
/I:         I=-13; DM=-32;
/M: SY='P';  M= -77, -91,  24, -68,  13, -81, -73, -82, -70, -33, -77,   8,  56, -13,   2,   8,  -4, -82, -86,  -1; D=-13;
/I:         I=-13; DM=-32;
/M: SY='H';  M= -18, -86,  10, -18, -81, -35,  65,  -7, -64, -28, -69,  13,   7,  -6,   9, -28,  22, -73, -96, -71; D=-13;
/I:         I=-13; DM=-32;
/M: SY='H';  M=  -2, -85,  -6, -14,   5, -81,  78, -67, -19, -14,   1, -68,  12, -65, -14, -70, -71,  -4, -78,  38; D=-13;
/I:         I=-13; DM=-32;
/M: SY='P';  M= -69, -84,  -1,   6,  11, -79, -68,   6, -14, -32,   0, -68,  52,  23, -69, -12,  19, -26, -76,  21; D=-13;
/I:         I=-13; DM=-32;
/M: SY='D';  M= -20, -83,  41,  30, -74, -29,  13,   3, -59, -37, -69,  38, -75,   4,   1, -26, -18, -70, -84,  18; D=-13;
/I:         I=-13; DM=-32;
/M: SY='M';  M= -67, -83, -71, -12, -62,  23, -65,  10, -63, -28,  44,  14, -80,  18,  22, -67, -68,   9, -74,  44; D=-13;
/I:         I=-13; DM=-32;
/M: SY='N';  M=   5, -75, -16,  -2, -76, -26,   8, -70,  20,  -7, -66,  69, -10, -57, -60,   3,   8, -32, -89, -72; D=-13;
/I:         I=-13; DM=-32;
/M: SY='Q';  M= -28, -78,  30,  12,  17,   3,   2, -69, -60, -31,   5, -58,  -6,  36, -16,  16,  22, -24, -81, -63; D=-13;
/I:         I=-13; DM=-32;
/M: SY='F';  M= -23, -79, -83, -76,  71, -82, -68,  17, -25,  -7,  29, -77, -13,   3, -72, -72, -67,   4,  62,  47; D=-13;
/I:         I=-13; DM=-32;
/M: SY='V';  M=  27,  11, -76,  -8, -60, -26, -76,  15, -70,  29, -48, -74, -78, -69,  -9, -64, -18,  48, -82, -66; D=-13;
/I:         I=-13; DM=-32;
/M: SY='D';  M=  -3,  23,  64,  26, -80, -21, -58, -27, -10, -76, -71,  41, -68,  11, -15,   9,  13, -70, -89, -71; D=-13;
/I:         I=-13; DM=-32;
/M: SY='Q';  M=  31, -73, -64,  -1,  17, -27,  23,   2,  22,  -5, -55, -10, -71,  34,  -4, -56,   3,   0, -75, -58; D=-13;
/I:         I=-13; DM=-32;
/M: SY='T';  M= -58, -69,  -4, -15, -61, -71, -65,  32,  14,  10,  10,  38, -69, -59, -61,   8,  45,  28, -82, -62;
/M: SY='L';  M= -63, -71, -73, -18, -48,  -3, -65,  10, -19,  69,  12,  -9, -11, -64, -69, -12, -60, -17, -71,   2;
/M: SY='E';  M=  14, -72,  21,  50, -69, -66, -60, -23,  16,  19, -57, -55, -66,  17, -13,  34, -54, -24, -78, -65;
/M: SY='M';  M=  40, -67, -14, -67, -56, -71, -71,  27, -23,  31,  41, -68, -73, -66, -69, -58,  10,  41, -78, -61;
/M: SY='V';  M= -17,  15, -77, -74, -53, -19,   6,  47, -73,  37, -41, -12, -77, -70, -74, -10, -56,  55, -79, -59;
/M: SY='K';  M= -27, -72, -10, -13,  38, -32,  14, -60,  55,  17,  12, -56, -70, -54,  -1,   9,  17, -60, -68,   0;
/M: SY='K';  M=  -8, -75,  40,  29,   0, -68,  36, -71,  58, -13, -62, -51, -66,  -6, -15,   6, -16, -68, -73,  10;
/I:         I=-42; MD=-106;
/M: SY='H';  M= -23, -77, -70, -71,  34, -76,  66,  -9, -66,  18,   9,  30, -81, -65,   4, -21, -63,   1, -69,  42; D=-42;
/I:         I=-42; MI=0; MD=-106; IM=0; DM=-106;
/M: SY='G';  M=  29,  16, -12,  13, -73,  50, -65, -63, -60, -23, -63,  18,   1, -59, -17,  13, -56,  14, -80, -71;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='Y';  M= -27, -75, -62, -21,  44,   9, -53, -61,  33, -11, -56,  27, -74,  -3,   0,  -8, -59, -31, -54,  73;
/M: SY='W';  M=   3, -72, -65, -25, -62,  -5,   7,  24,  16,  12, -53,  -5,  -8,   0, -61,  30,   9,  -5,  61, -59;
/M: SY='R';  M=  -6, -73,   6,   7, -75, -21, -57, -30,  30, -70,  19,   1, -66,  31,  46,  40,  16, -66, -79, -65;
/M: SY='K';  M= -63, -79,  23,  -9, -79, -26,  48, -81,  56, -77, -65,  44, -68,  49,  54, -54, -59, -78, -80, -62;
/I:         I=-26; MD=-67;
/M: SY='A';  M=  33, -78,  28, -58, -84, -68,   7, -79,  17, -79,   3, -58, -11,  -3,   8,  25,  17, -72, -89, -74; D=-26;
/I:         I=-26; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='D';  M= -71, -84,  66, -60, -78, -31, -71, -18, -65, -16,  30, -61, -80, -68,  23, -23,   9,  13, -96, -74; D=-26;
/I:         I=-26; DM=-67;
/M: SY='I';  M= -67, -83, -75, -66, -68, -82, -72,  37,  31, -28, -59, -68, -12,  29,  11,   8, -13,  14, -80,  10; D=-26;
/I:         I=-26; DM=-67;
/M: SY='V';  M= -27, -71, -77, -74,  41, -79, -73,  48, -72,  10,  13, -19,  16, -72, -74, -64,  13,  50, -69,   0;
/M: SY='W';  M=  15,  11, -80, -72, -49, -73, -72,  39, -13,   6,  40, -73, -75, -66, -69, -10, -59,  32, 100,  28;
/M: SY='F';  M=   1, -69, -79, -73,  67, -76, -70,  10, -73,  47, -42, -73, -79, -10, -72,   8, -58,  26, -63, -44;
/M: SY='S';  M=   3, -72, -59, -17, -11, -60, -60, -69,  -8, -70,   5, -53,  46,  58, -57,  66,  15, -66,  34, -62;
/M: SY='S';  M=   2,  17, -15,  13, -74, -55,   9, -73, -54, -74, -68,  -2, -64, -50, -17,  85,  27, -65, -84, -66;
/M: SY='F';  M= -68,  31, -72, -25,  81, -79,  34, -20,   9, -23, -53, -65, -78, -64,  27, -65, -10, -11, -53,  52;
/M: SY='N';  M= -61, -74,  61, -12, -80, -59,  35, -78, -49, -79, -69,  79,  -9,  50, -13,  17, -14, -77, -90, -66;
/I:         I=-33; MD=-84;
/M: SY='W';  M=   5, -85, -78, -11,  50, -77,  -3, -25, -24, -25, -67, -76,  46, -70, -16,   5, -69, -70,  86, -53; D=-33;
/I:         I=-33; MI=0; MD=-84; IM=0; DM=-84;
/M: SY='S';  M=  13, -77, -18, -75,   0,  17, -77,  25, -76,   8, -59, -68, -79, -72, -79,  40, -60,   1, -82, -68; D=-33;
/I:         I=-33; DM=-84;
/M: SY='C';  M= -18,  84, -76, -68, -57, -79, -68,  18,   6,  38,  14, -68, -79, -62,  46, -66, -60,  13, -79, -62;
/M: SY='W';  M= -12,  11, -63, -17, -66, -68, -63,   5,   7,  -7, -56,   4,  16,  39,  25,  24,  15,   2,  59, -61;
/M: SY='I';  M=  12, -74,  -6, -64, -56, -75,   8,  56,   4,  12,  48, -15, -73, -59,  35, -63, -59,  -7, -74,  -2;
/M: SY='C';  M=  -1,  70, -10, -69, -15, -17, -74,  23,   4,  33, -46, -68, -77, -69, -69, -63, -15,  43, -79, -61;
/M: SY='R';  M=  -9, -75,   9,  -6,  -6,  15,  10, -74, -44, -35, -63,  53, -71,  18,  62, -21,  -5, -71, -75,   2;
/M: SY='W';  M= -22, -78,  30,  31, -69, -68, -60, -72,  10, -16, -64, -54, -67,  44,  35,  20,  14, -70,  93, -58;
/M: SY='K';  M=   7, -72, -69, -61,  38, -28, -61, -53,  50,  31,   8, -63, -73, -56,  30, -61, -13, -20, -64,  22;
/M: SY='Q';  M=  35, -74,  29,  -9,  14, -13, -56, -67,   3,  -7, -58,  -3, -69,  82, -53, -52, -59, -65, -71,  -8;
/M: SY='P';  M= -62, -80, -60, -57, -18, -65, -63, -66, -16, -26, -64,  45, 101, -60,  -4,   5, -10, -17, -79, -71;
/M: SY='N';  M= -57, -72, -53,   6, -72,  30,   1, -70,  31, -10, -62,  55, -68, -50,  37,  16,  13, -31, -80, -66;
/M: SY='Y';  M= -66, -74, -76, -74,  57, -17, -57,  30, -67,  14,  65, -12, -78, -67,  -7, -66,  -7, -47, -53,  70;
/M: SY='P';  M= -61, -83, -57,  30, -81,   3, -63, -74,   7, -34, -66, -61,  95,  40, -19, -19,  -6, -74, -78, -74;
/M: SY='M';  M= -59, -71, -68, -61, -59, -75,   8,   1,  12, -24,  68, -61,  -6,  18,  23, -57,  47,  39, -76,   9;
/M: SY='F';  M=   3, -71,  -6, -18,  48,  20, -67,   8, -69,  32, -47,  -7, -75, -68, -72, -61, -14,  24, -67,   1;
/M: SY='W';  M= -64, -73, -79, -73,  69, -30,   8, -42, -72,  29, -46, -74,  -1,  -8, -72, -22, -62,  38,  70,  27;
/I:         I=-26; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='L';  M= -62, -72, -66, -62, -56,   7, -63, -20,  44,  57, -45,  26,  -7, -58,  -1, -62, -12, -18, -75, -61;
/M: SY='T';  M= -58,  16, -71, -66,  34, -29,   2,  21, -23,  19,  21, -63, -73,  28, -66,   8,  35,  28, -73, -52;
/M: SY='W';  M=   1, -75,   8,  30, -69, -67, -59, -18,   5, -22,  18,  -7, -67,  51,  29,  12,  -4, -22,  67, -60;
/I:         I=-21; MI=0; MD=-53; IM=0; DM=-53;
/M: SY='E';  M= -25, -75, -17,  56,   8,  49, -63, -19, -56, -24, -62,  -5, -15,   1, -12, -54,   8,  -5, -75, -64;
/M: SY='K';  M=   9, -75,   4, -12, -14,  27, -59, -72,  51, -73, -65,  19, -10,  20,  -7, -14,  -8, -34,  33,   9;
/I:         I=-11; MD=-28;
/M: SY='T';  M= -60, -72,  -2, -62,  28, -74,  21, -10,   5,  -8,   3, -58, -72,  -5,   6,   7,  49,  22, -71,  25; D=-11;
/I:         I=-11; MD=-28;
/M: SY='W';  M=  32, -75,  28, -59,  -8, -31,  21,  22, -61, -30,   7, -60,   9,  23,  -9, -56,  16, -21,  39,  17; D=-11;
/I:         I=-11; MD=-28;
/M: SY='D';  M=   0,  24,  36,   5,  -7, -74, -64,   4, -63,   2,   2,   8, -76, -13, -14, -19, -59,  31, -76,  24; D=-11;
/I:         I=-11; MD=-28;
/M: SY='W';  M=  -3,  31,  14,  11, -59, -78, -70,  18, -65,  18, -56, -68, -77, -64,   5, -23,   7, -13,  64,  23; D=-11;
/I:         I=-11; MD=-28;
/M: SY='P';  M= -65, -79,   6, -66, -71, -75,   8, -20, -64,  10,   6,  -6,  35, -65,  18,  27,  23,   4, -89, -70; D=-11;
/I:         I=-11; MD=-28;
/M: SY='Q';  M= -10, -85,  12,  18, -80, -79, -69, -21,  -4,  -2,   9, -66,  -7,  28,  22,   7, -19, -71, -88, -74; D=-11;
/I:         I=-11; MD=-28;
/M: SY='T';  M= -72, -86, -18,  -5, -11, -82, -73, -75, -67, -18, -73, -18,  22, -69,  15,  24,  29, -29, -85,  18; D=-11;
/I:         I=-11; MD=-28;
/M: SY='Q';  M=  -7, -92,  14,  12, -84, -83, -72, -82, -67,  -9,   2,   2, -86,  35,   6,  -3, -74, -82, -92,  -2; D=-11;
/I:         I=-11; MD=-28;
/M: SY='W';  M=  24,-102,  20, -79, -96, -91, -92, -26, -87, -20, -85, -86,  -2,  27, -91, -82, -86, -85,  31, -90; D=-11;
/I:         I=-11; MI=0; MD=-28; IM=0; DM=-28;
/M: SY='M';  M=  14, -85, -88, -22, -77, -38, -85, -13, -22,  -7,  55, -83, -87, -79, -83, -74,   8,  19, -96, -79; D=-11;
/I:         I=-11; DM=-28;
/M: SY='V';  M=  -7, -82, -77,   4,  12, -84, -78, -23,  -2,  -1,   4, -75,  -8,  -3, -73, -25,  18,  23, -86, -69; D=-11;
/I:         I=-11; DM=-28;
/M: SY='Q';  M= -12, -83,  15,  23,  19, -75,  12, -33, -17, -73, -69,  13, -76,  43,  27, -22, -18, -28,  33, -62; D=-11;
/I:         I=-11; DM=-28;
/M: SY='F';  M=   1, -77, -75,   8,  67, -81, -73,  19, -19, -17,   8, -72, -78, -71, -72, -66,  27, -17,  28,   1; D=-11;
/I:         I=-11; DM=-28;
/M: SY='A';  M=  48,  16, -12, -59,  -3, -68,   8, -66,  32, -12,  10, -62, -74,   0,  20, -25, -20, -26, -79, -64; D=-11;
/I:         I=-11; DM=-28;
/M: SY='M';  M= -22,  11, -60,  21, -10, -25, -63, -28,  28, -32,  45,  -9,  -8,  -5, -57,  27,  43, -24, -80, -64; D=-11;
/I:         I=-11; DM=-28;
/M: SY='N';  M= -63, -75, -60, -62,  42,  20,  12, -18, -19,  -5, -57,  52, -19,  -3,  49,  -6, -59, -65, -66,  25;
/M: SY='W';  M=  46,  40, -64, -21, -67,  20, -67,  14, -63, -66, -62,  32,  35, -62, -70,   3, -56, -22,  58,   0;
/M: SY='N';  M= -55,  15,  43, -49, -74, -60, -55, -66,   6, -37, -64,  56, -68,  48, -55,  46,  28,  -6, -86, -67;
/M: SY='G';  M=  22, -73,  -6, -67,  26,  40, -67,  15, -17,  20, -53, -61, -73, -63,   8, -20, -18, -54,  39,  -7;
/M: SY='I';  M= -27, -71, -82, -75,  31, -83, -72,  48, -73,  45,  27, -76, -79,   4, -73, -70, -59,  44, -69,  -7;
/M: SY='N';  M= -56, -72, -55, -66, -69,  62,  49, -66, -62,  15, -59,  69, -72, -59, -66,   9, -57, -20, -82, -65;
/I:         I=-36; MD=-90;
/M: SY='V';  M= -18, -75, -20, -71, -56, -78, -71,  42, -69,  17,  34,  -1,  40, -69, -15, -67, -58,  47, -77,   2; D=-36;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='P';  M=  -6,  28,  25, -51, -79, -60, -59, -75,  16, -78, -69,  46,  66,  -3, -12,  45,  -8, -72, -84, -72;
/M: SY='Y';  M=   8,  28,  16, -60,  -3, -70,  59, -28,  24, -31, -57,  -6, -75, -58, -57, -61, -62, -24,  73,  82;
/M: SY='T';  M=  -8,  11, -10,  31,  -8, -64,  14, -69,  29, -31, -62,  30,  -9,  -6, -54,  30,  31, -66, -73,  28;
/I:         I=-26; MD=-67;
/M: SY='W';  M= -15, -99, -88,  -3, -78, -92, -83, -81, -81, -40,   8, -88, -10, -80,  -7,  13, -80, -15,  38,  34; D=-26;
/I:         I=-26; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='L';  M= -27, -71,  22, -58, -10, -34, -61, -20,  16,  54,  14,   1, -73,  23, -20,  23, -56, -53, -75, -58;
/M: SY='L';  M= -66, -73,  -3, -70,  34, -82, -67,  21,   9,  57,  23, -73, -79, -67, -67, -72, -62,  12,  48,  11;
/M: SY='M';  M= -61, -73,  21,  20,  10, -69, -57,  -4, -23, -10,  69,  26,  35, -56, -63,  17,   8, -57, -71,  26;
/M: SY='C';  M=   4,  50,  13,  26, -73, -29,  37, -71,   6, -71, -64, -56,  46,  -3,  44, -56,  -8, -14, -79,  -4;
/M: SY='P';  M=  -1, -74,  12,   0, -74,   2,  20, -25,  20, -21, -62,  14,  59,  -1, -58, -16,  41, -64, -81, -68;
/M: SY='S';  M=   4, -74, -17,  11,  -1,  -2, -57, -19, -52, -67,   0,  16,  16,  38,  19,  45, -53, -31, -70,  24;
/M: SY='L';  M= -61,  15,  13, -66,   4, -77, -67,   1, -68,  50,  39, -66,  -6,  -2, -70, -23,  30,  25, -76, -56;
/M: SY='K';  M= -12, -75,  -4, -55,  14, -33,   7, -18,  43, -59,   7, -59,  19,  25,  23, -58,  -6,  28, -69,  29;
/I:         I=-25; MD=-63;
/M: SY='W';  M= -82,  22,  29, -72, -20, -29, -84, -77,   1, -32, -79, -77, -92,  23,  -2, -80, -81,   7,  71, -74; D=-25;
/I:         I=-25; MI=0; MD=-63; IM=0; DM=-63;
/M: SY='D';  M=  21, -74,  41,   6,  -2, -16,  39,  15,  15, -29,  34, -54, -69,  19,  12, -23, -59, -26, -77, -58;
/M: SY='I';  M=  22, -73, -77, -71,  -9, -75, -67,  56, -18,  23,   3, -71, -75, -65,  -7, -22, -58,  13,  34,  43;
/M: SY='K';  M=  -6, -76,  -2, -46, -73, -65,  55, -76,  59, -73, -63,  15, -67,  53,  36,   9, -11, -73, -76,   2;
/M: SY='Q';  M=  34, -72,  25,  -9, -79, -59, -56, -72,  34, -37, -64,  14, -66,  71, -49,  41, -52, -68, -78, -66;
/M: SY='W';  M=  11, -74,   9, -57,  17, -32,  44, -64,   2,  15, -57,  45, -73,  20,  24,  -9, -59, -65,  70, -52;
/M: SY='G';  M= -53, -74, -58, -68, -75,  85, -63, -77, -17,  -2, -66,  52, -70,   3, -67, -51, -62, -76, -76, -72;
/M: SY='L';  M= -64, -70, -82, -75, -45, -85, -70,  35, -23,  70,  45, -78, -80, -68, -19, -73, -60,  22, -74, -55;
/M: SY='P';  M=  16, -74, -62,  -4, -72, -22, -63, -58,   6,  -5, -57, -15,  57,  49,   7,  14, -55,  20, -78, -67;
/M: SY='V';  M= -57,  35, -79, -74, -54, -80, -78,  28, -73,  24, -43, -74,  23, -73, -76, -12, -10,  74, -83, -62;
/M: SY='Y';  M= -67, -73, -11, -69,  59, -75,  37,  14, -65,   4,  21,  39, -79, -65, -25, -65, -60,  16, -57,  65;
/M: SY='P';  M=  25,  36, -75, -69,  -7, -17, -73, -11, -69,  23,   7, -69,  44, -69, -73, -20,   4,  36,  38, -60;
/I:         I=-22; MD=-55;
/M: SY='W';  M= -87,-106,  -5, -18, -82, -23, -87, -94, -30, -97, -93, -86,-100, -83, -18,  13, -86, -25,  62,  35; D=-22;
/I:         I=-22; MI=0; MD=-55; IM=0; DM=-55;
/M: SY='W';  M= -69, -81, -19,  11,  57, -78, -64, -53, -68, -24, -56, -76, -78, -67, -69, -71, -68,  15, 127,  75;
/M: SY='T';  M=   7,  17,  22,  -9,  -5, -10, -67, -14, -62,  -6, -57,  -8, -67, -62, -68,  -4,  71,  12, -82, -63;
/M: SY='V';  M=   5, -69, -69,  14,   3, -75, -71,   9, -67,  16,  21,   9,  -6, -65, -70, -62, -15,  65, -78, -59;
/M: SY='N';  M= -63, -70,  52, -49, -78, -55, -46, -77,  12, -82, -71, 109, -70, -50, -54, -47,  -2, -77, -95, -71;
/M: SY='E';  M=  -1, -73,  40,  40, -78, -22, -58, -72,  26, -74, -68,  12,   6,   9, -19,  28,  26, -23, -83, -69;
/M: SY='P';  M= -63, -79, -61,  20,  17, -73, -63, -56,  12,  -5, -57,  -6,  72,  42, -59, -60,  -8,  18,  39,  -3;
/M: SY='W';  M=   0, -77,  53,  35, -65, -67, -59,   8, -22, -30, -62,  -3, -68,  38, -59,  18, -57, -18,  77,   9;
/M: SY='D';  M= -62, -75,  61,  37, -73, -66, -55, -70,  24,   8, -64,  40,   9, -49,  10,  10, -19, -69, -84, -67;
/M: SY='Y';  M=  30, -72, -75, -72,  55,   8, -61,  29, -22, -49,  28, -68, -75, -66, -19, -60, -61,   2, -54,  68;
/M: SY='D';  M= -10, -75,  63,  -9, -73, -21,  10, -75,  15, -25, -66,  35, -68,  25,  26,  23, -55, -72, -81,  -3;
/M: SY='R';  M=  -3, -74, -66, -19,  14,   9, -59, -23,  20,  20, -53, -61, -73,   1,  43,  12, -59, -19, -64,  38;
/M: SY='L';  M=  38,  11, -73, -65,  36, -11,  17, -50, -66,  45, -46, -67, -76,  39, -66, -59, -61, -17, -64,  25;
/I:         I=-36; MD=-90;
/M: SY='W';  M= -68,   8, -73,   3,  18, -81,  21,  -4,   2,  32,  23, -71, -78, -11,   8, -70, -66,   2,  77,  36; D=-36;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='C';  M= -30,  52,  50,  50, -74, -20,   9,  26,  11, -67, -64, -52, -67,   8,   7,   6, -58, -62, -83, -67;
/M: SY='W';  M=  39, -70, -71, -67,  32, -65, -64,  -8, -62,  21,   3,  -7,  -6, -62,   7,  25, -56, -21,  61,  18;
/M: SY='G';  M= -53, -76, -65, -71, -10,  84,  13, -78, -65, -74,  10, -53, -12, -63, -19,  15, -63, -76, -66,  38;
/M: SY='V';  M=  42,  13, -78, -72, -57, -72, -78,  22, -71,   2, -45, -72, -75, -70, -74, -20, -52,  75, -82, -63;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='D';  M=  -6, -75,  85,   3, -81, -11,   8, -80, -13, -80, -73,  54,  -7, -52,  -4, -51,   8, -75, -92, -69;
/M: SY='G';  M=  21,  10, -67, -68,  -9,  66, -66, -68, -66,   2, -61, -56, -70,  -1, -70,  25,  -5, -65,  33,   8;
/M: SY='V';  M=   1, -69, -78, -71, -53, -79, -74,  40, -19,  30,  30, -72, -75,  -3, -70, -64,  -7,  64, -79, -59;
/M: SY='I';  M= -23,  10,  -7, -73,  43,   1, -71,  56, -72,  28,  39, -67, -75, -71, -75, -64,  19, -17, -69, -51;
/M: SY='T';  M= -53, -67, -55,  26, -60, -67, -59, -57, -56, -63, -59,  -3, -64,   7, -62,  36,  79,  13, -73,  43;
/M: SY='D';  M= -25,  15, 102,  -2, -84, -63,  10, -83,  11, -82, -77,  38, -67, -52, -57, -54, -56, -79, -97, -69;
/M: SY='Y';  M= -10,  11,   8, -57,  44, -66,  38, -66, -14, -62,  19,  47,   5,  28,   8,   6, -57, -67, -64,  50;
/M: SY='P';  M= -27,   4, -70,  -9,  22, -19, -73,  46, -67, -57, -55, -70,  90, -68, -75, -20, -58,  12, -74, -63;
/M: SY='D';  M= -62, -75,  48,   2,  -1,   9,  38, -21, -62,  25, -54, -56,  24, -10, -66, -58,  28, -23, -73,  23;
/M: SY='M';  M=  44, -70, -16, -14, -19, -67,   8, -16,  38,  -1,  44, -59, -69, -56, -14, -54,  30, -21, -78, -62;
/M: SY='A';  M=  43, -72, -75, -18,  11, -73, -75,  22, -19,  30, -51, -71, -75, -68, -72, -59,  29, -15,  31, -60;
/M: SY='R';  M= -21, -82, -65,  11, -73, -29,   8,  -3, -16, -70,   4, -62,   5,  25,  55,  27, -62, -23, -79,   7;
/M: SY='Q';  M=   2, -83, -10, -52, -84, -71,  43, -83,  46, -80, -69,  -4,  13,  49,  47,  -8, -63, -79, -84, -68;
/M: SY='W';  M=  -2, -82, -22,  21,  16,   0, -68, -63, -67,   6,   1,  19, -80, -66, -15, -68, -69,  -5,  69,  29;
/M: SY='L';  M= -67,   7, -75, -69, -13, -36, -69, -57,   4,  30, -56, -13, -10,  14,  14,   5, -13,  10, -78,   9;
/I:         E1=0; IE=-380; DE=-380;

» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	70 in 63 different sequences
Number of true positive hits	70 in 63 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	2
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Feature key [info]	DOMAIN
Feature description [info]	GP-PDE
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

63 sequences

GDE1_BOVIN  (Q3T0T0), GDE1_CANAL  (A0A1D8PNZ7), GDE1_EREGS  (Q74ZH9),

GDE1_HUMAN  (Q9NZC3), GDE1_MOUSE  (Q9JL56), GDE1_RAT(Q9JL55), 
GDE1_SCHPO  (Q9C104), GDE1_YEAST  (Q02979), GDPD1_ARATH (Q9SGA2), 
GDPD1_HUMAN (Q8N9F7), GDPD1_MOUSE (Q9CRY7), GDPD1_RAT   (Q0VGK4), 
GDPD2_ARATH (Q9FLM1), GDPD2_HUMAN (Q9HCC8), GDPD2_MOUSE (Q9ESM6), 
GDPD3_ARATH (Q680A6), GDPD3_HUMAN (Q7L5L3), GDPD3_MOUSE (Q99LY2), 
GDPD4_ARATH (F4I8H8), GDPD4_HUMAN (Q6W3E5), GDPD4_MACFA (Q95JR7), 
GDPD4_MOUSE (Q3TT99), GDPD5_ARATH (Q9C907), GDPD5_CHICK (Q3KTM2), 
GDPD5_HUMAN (Q8WTR4), GDPD5_MOUSE (Q640M6), GDPD6_ARATH (Q9SD81), 
GDPD_BACAB  (A0A8F4N283), GDPD_CALS4  (Q8RB32), GLPQ1_MYCTO (P9WMU2), 
GLPQ1_MYCTU (P9WMU3), GLPQ2_MYCTU (O07244), GLPQ_BACSU  (P37965), 
GLPQ_ECOLI  (P09394), GLPQ_HAEIN  (Q06282), GLPQ_TREPA  (O30405), 
GPCP1_CAEEL (Q21407), GPCP1_HUMAN (Q9NPB8), GPCP1_MOUSE (Q8C0L9), 
GPCP1_RAT   (Q80VJ4), GPCP2_CAEEL (Q10003), GPDL1_ARATH (Q7Y208), 
GPDL3_ARATH (Q9SZ11), GPDL4_ARATH (Q9FJ62), GPDL5_ARATH (F4JEQ1), 
GPDL6_ARATH (Q9FGT9), GPDL7_ARATH (Q9LVN0), LRL26_ARATH (D7SFH9), 
NUC2_NEUCR  (Q01317), PGC1_SCHPO  (O14169), PGC1_YEAST  (Q08959), 
PHO81_YEAST (P17442), UGPQ_ECOLI  (P10908), Y2277_MYCTO (P9WLF0), 
Y2277_MYCTU (P9WLF1), Y293_MYCGE  (P47535), Y385_MYCGE  (P47625), 
Y420_MYCPN  (P75367), Y4ED_SINFN  (P55427), Y566_MYCPN  (P75212), 
YHDW_BACSU  (O07592), YQIK_BACSU  (P54527), YRU3_CAEEL  (Q10049)

» more

Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

PDB
[Detailed view]

8 PDB

1T8Q; 1YDY; 2PZ0; 5T91; 5T9B; 5T9C; 5VUG; 8CWP