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PROSITE entry PS51684


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PURL: https://purl.expasy.org/prosite/signature/PS51684

Direct ScanProsite submission
General information about the entry

Entry name [info] SAM_MT_TRM5_TYW2
Accession [info] PS51684
Entry type [info] MATRIX
Date [info] 01-AUG-2013 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51555
Associated ProRule [info] PRU01021

Name and characterization of the entry

Description [info] SAM-dependent methyltransferase TRM5/TYW2-type domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=264;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=259;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6157651; R2=0.0083825; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=17352.2695312; R2=17.3606586; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=2074; H_SCORE=53358; N_SCORE=20.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=464; H_SCORE=25408; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-33; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 76 in 76 different sequences
Number of true positive hits 76 in 76 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] SAM-dependent MTase TRM5/TYW2-type
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
76 sequences

TAW21_SACS2 (Q97W08), TAW22_NANEQ (Q74NE4), TAW22_PYRAB (Q9V2G1), 
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PDB
[Detailed view]
15 PDB

2YX1; 2ZZM; 2ZZN; 3A25; 3A26; 3A27; 3AY0; 3K6R; 5HJI; 5HJJ; 5HJK; 5HJM;
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