PROSITE entry PS51666

View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission

General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51666
Entry name [info]	QLQ
Accession [info]	PS51666
Entry type [info]	MATRIX
Date [info]	01-FEB-2013 CREATED; 13-FEB-2019 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51666
Associated ProRule [info]	PRU01001

Name and characterization of the entry

Description [info]

QLQ domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=36;
/DISJOINT: DEFINITION=PROTECT; N1=4; N2=33;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4185576; R2=0.0086588; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=3940.5703125; R2=1.0259246; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1049; H_SCORE=5017; N_SCORE=11.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=472; H_SCORE=4425; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-62; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='P';  M=  22, -96, -45, -80, -47,   3,  22, -11, -78, -15, -30, -23,  68,   2, -31,  33, -20, -48,  -5, -13;
/M: SY='F';  M= -99,-151, -65,-159, 114,-162, -38,   9,-156,  14,   2, -57,-163,-160, -79,-152,-145,-104,-127, -26;
/M: SY='T';  M= -80,-143,-134,-105,-149, -87,-142,-142, -45, -48, -80,  36, -44,-136,-142,  53, 101,-136,-165,-146;
/M: SY='P';  M=  29,-155, -17, -12, -20, -84, -17, -53,   8, -38, -19,   4,  78,  40, -75,  -6, -14, -53, -18,-145;
/M: SY='Q';  M=  44,-150,  15,  34,-152,-141, -52, -43, -39, -43,  12,  20, -56,  54,-137,  23,  -1, -18,-158, -47;
/M: SY='Q';  M=-139,-163, -63,-114,-167, -89, -55, -71,-120,-149, -39, -54,-146, 138,-120,-128,-141,-155,-152,-140;
/M: SY='W';  M= -49,-154,-162,-153,  -5,-157,-151,  13,-100,  59,  30,-156,-158, -40, -16,   5,-142,  -5, 114, -44;
/M: SY='Q';  M=   7,-154,  -4,  20, -16, -81,  57, -67, -21, -47,  46,  35, -55,  79, -21, -38, -15,-106,-157, -75;
/M: SY='Q';  M= -28,-154,-133,  69,-143, -91,-138, -47,-132,  41,  10,-142,-147,  75, -66,-138, -18,  -3, -58,-141;
/M: SY='L';  M=-146,-149,-164,-157,   6,-165,-148, -20,-157,  93, -25,-162,-163,-151,-155,-156,-142, -51,-148,-130;
/M: SY='R';  M=-143,-160, -59,  61, -66,-135, -16,-161,  67,-155, -82,-133,-145, -37,  81, -87,-141,-155, -24,-143;
/M: SY='H';  M=  65, -81, -63, -87,-150, -73,  73,-146,-134, -25, -31,  15,-148,  48,  -4,  -2,   4, -71,-159, -35;
/M: SY='Q';  M=-139,-164,-134,-113,-168,-147, -14,-155,-119,-150,-137,-129,-146, 139,-119,-128,-141,-157,-152,-140;
/M: SY='I';  M=  42,-149,-157,-153, -10,-153,-156,  81,-151, -36,   5, -74,-152,-149, -90, -19, -60,  36,-154, -75;
/M: SY='M';  M= -13,-149,-147, -29, -33, -47, -15, -52, -14,  52,  75, -42,-151,  41, -41, -28,  25, -37,-151, -15;
/M: SY='A';  M=  84,-144,-151,-145,-143,-113,-152,  62,-146, -85, -58,-144,-147,-142,-150,  -8, -45,  -3,-155,-144;
/M: SY='Y';  M=-151, -57,-156,-156,  85,-159,-100, -71,-150,   2,-126,-153,-163,-149,-147,-120,-144, -87,-114, 116;
/M: SY='K';  M=-142,-157,-134, -55,-157, -55,-134,-159, 100,-156,-144, -12,-145,  10,  64,-135,-138,-154,-152,-144;
/M: SY='Y';  M= -38,  59,-150,-147,  -9, -92,  50, -97, -32,  17,  60, -63,-157, -12, -20, -85, -63, -97, -65, 100;
/I:         I=-29; MI=0; MD=-75; IM=0; DM=-75;
/M: SY='M';  M= -76,-148,-160,-153,  11, -99,-145,  39, -54,  77,  79, -68,-157,-146, -89,-151,-139,-115,-147,-128;
/M: SY='A';  M=  58,-144,-143, -45, -76, -38,-114, -27,  11, -49,  41, -76,-145, -30, -35,  50,  -5,  29,-156,-142;
/M: SY='R';  M=  52,-150,-137,-129,-152,-105, -37,-151,  49,-150,-141,  16, -15,   2,  73,   3, -54, -87,-152, -19;
/M: SY='N';  M= -85,-150,-126, -90,-156,  66,  -6,-159, -12,-160,-148,  96, -56,  -4,   5,   2, -91,-156,-160,-149;
/M: SY='Q';  M=  17, -84, -49,  11,-105, -55,-138, -25,  -1,  28,  37, -93, -49,  82, -71, -36, -51,  21,-153,-139;
/M: SY='P';  M= -27,-161, -64,-134, -67,  13, -72,-149, -60, -80,-145, -38, 114,   6, -30,  -8, -32, -44,-155, -58;
/I:         I=-22; MI=0; MD=-55; IM=0; DM=-55;
/M: SY='V';  M=-122,-148, -76,-155, -42,-163,-157,  65,-153,  28,  -2,-155, -23,-152,-155,-147, -60,  78,-156, -73;
/M: SY='P';  M= -52,-164, -67, -53,-161,-144,-146, -94, -79, -93,-147, -90, 127,-141,-150,  16, -51,-153,-157,-158;
/M: SY='P';  M= -24,-155,   4,  23, -37, -60,   8, -59, -60, -60,  -3, -31,  76,  55, -35,  15,  11, -12,-155, -13;
/M: SY='H';  M= -24,-155,  31,  51,-151, -45,  81,-156,-101,-114, -87,  43, -33,  58, -31,  11, -34,-153,-158,  13;
/M: SY='L';  M= -72, -19,-160,-154, -51,-161,-147,  17,-153,  79,  27,-156,-159, -56,-152, -80, -32,  25, -83,  -4;
/M: SY='Q';  M=  -5,-152,-148, -52, -91, -97,-141,  22, -50,  46,  10, -99, -47,  86, -48,-114, -68,  26,-152, -46;
/M: SY='Q';  M=  -5,  -6, -12, -20,  -2, -76, -25, -11, -14,  23,  38,  10, -68,  70,  -3,   3, -40, -18,-152, -38;
/M: SY='P';  M=  46,-151, -70, -28,   6, -65, -62, -23, -30, -26, -33, -40,  72,  30, -25,   3, -36,   4,-152, -58;
/M: SY='I';  M=  12,-150,-108,-154, -68,-158,-156,  84,-152,  22,  11, -84, -36,-149,-104, -55, -37,  38,-154,-136;
/M: SY='W';  M= -52, -64, -78, -86,  42, -61, -44, -56,  12, -80,   2, -14, -18,  70,  30,  10,  15, -19,  81, -12;
/M: SY='K';  M=  -2,-153,-135, -10,-152,  33, -36, -57,  44, -45,   1,  42,  33, -12,  26,   2, -38, -43,-155, -53;
/I:         E1=0; IE=-380; DE=-380;

» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	35 in 35 different sequences
Number of true positive hits	35 in 35 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Feature key [info]	DOMAIN
Feature description [info]	QLQ
Version [info]	5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

35 sequences

BRM_ARATH   (Q6EVK6), BRM_DROME   (P25439), GRF10_MAIZE (A5HEG9),

GRF10_ORYSJ (Q6EPP9), GRF11_ORYSJ (Q6AWX8), GRF12_ORYSJ (Q6AWX7), 
GRF1_ARATH  (O81001), GRF1_MAIZE  (A0A060D764), GRF1_ORYSI  (A2XA73), 
GRF1_ORYSJ  (Q6AWY8), GRF2_ARATH  (Q8L8A8), GRF2_ORYSJ  (Q6AWY7), 
GRF3_ARATH  (Q9SJR5), GRF3_ORYSJ  (Q6AWY6), GRF4_ARATH  (Q8L8A7), 
GRF4_ORYSJ  (Q6ZIK5), GRF5_ARATH  (Q8L8A6), GRF5_ORYSJ  (Q6AWY4), 
GRF6_ARATH  (Q9ZQ12), GRF6_ORYSJ  (Q6AWY3), GRF7_ARATH  (Q9FJB8), 
GRF7_ORYSJ  (Q6AWY2), GRF8_ARATH  (Q9SU44), GRF8_ORYSJ  (Q6AWY1), 
GRF9_ARATH  (Q8S9M3), GRF9_ORYSJ  (Q9FRG8), SMCA2_HUMAN (P51531), 
SMCA2_MOUSE (Q6DIC0), SMCA4_BOVIN (A7Z019), SMCA4_HUMAN (P51532), 
SMCA4_MOUSE (Q3TKT4), SMCA4_RAT   (Q8K1P7), SNF22_SCHPO (O94421), 
SNF2_YEAST  (P22082), SWSN4_CAEEL (G5EF53)

» more

Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

PDB
[Detailed view]

10 PDB

6LTH; 6LTJ; 6UXV; 6UXW; 7C4J; 7VDT; 7VDV; 7VRB; 7VRC; 7Y8R