PROSITE entry PS51656
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General information about the entry
| Entry name [info] | 4FE4S |
| Accession [info] | PS51656 |
| Entry type [info] | MATRIX |
| Date [info] |
01-AUG-2012 CREATED;
13-FEB-2019 DATA UPDATE; 27-MAR-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51656 |
| Associated ProRule [info] | PRU00989 |
Name and characterization of the entry
| Description [info] | 4Fe-4S domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=60; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=55; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.6618776; R2=0.0096750; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=7979.3476562; R2=1.5019256; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=966; H_SCORE=9430; N_SCORE=11.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=501; H_SCORE=8732; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-46; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='E'; M= -7,-154, 16, 69, -40, -55, -32,-150, 18,-147, 27, -14, 2, 43, 24, 4, -38, -59,-155, -46; /M: SY='K'; M= -13,-151, 11, 31, -56, -53, -17, 37, 38, 22, 0, -77, -18, -7, -78, -30, -42, 13,-153, -25; /M: SY='D'; M= 15,-151, 55, 18,-146, -49,-137, -5, 25, -5, 30, 16, -49, -7, 3, -34, -31, -3, 2, -74; /M: SY='P'; M= -22,-155, 33, 57,-156, -80,-136,-150, 9, -51,-145, 9, 67, 17, -4, 21, -31, -36,-159,-148; /M: SY='R'; M= -20, -56, -53, -38, -37, -46, -63, 29, 21, 15, -16, 13, -17, -3, 32, -8, 10, 30,-155,-139; /M: SY='I'; M= -1,-149,-156, -55, 22,-156,-151, 63, -71, 17, -1,-151, 11, -94,-151, -53, -30, 51, -29, 6; /M: SY='E'; M= 2, -64, 26, 53,-145, -51, -23, -18, 18, 21, -7, 10, -91, -11, 8, -52, 19, -45,-157, -77; /I: I=-26; MD=-67; /M: SY='E'; M= -12,-155, 7, 64,-152,-102, -26, -7, 15, -26, -37, -3, -46, 31, 42, 7, -33, -63,-157, -88; D=-26; /I: I=-26; MI=0; MD=-67; IM=0; DM=-67; /M: SY='I'; M= -21, -50, -53, -31, -64, -57, -64, 76, -17, 13, 54,-146,-150, -84, -34, -29, -11, 31,-153, -71; /M: SY='Y'; M= -52, -67, 4, 0, 22, 31, 10, -51, -11, 19, 10, 8, -69, -59, -40, -67, -36, -36, -43, 76; /M: SY='K'; M= 20, -33, 14, 24, 2, -23, -26,-153, 80,-152,-144, 10, -43, -13, -4, -10, -93,-148,-152,-141; /M: SY='Y'; M= 0, 9, -93, 4, 22,-152, -38, 20, -12, 35, 10, -38, -35, -29, -26, -32, 9, 2, -1, 40; /M: SY='L'; M= -98, -53, -15, -86, -83, -46,-144, -76, -44, 84, -29, -84,-155,-143, -93, 5, 20, -21,-152, -68; /M: SY='P'; M= -15,-163, -3, 24,-160, -46,-143, -97, -36, -49,-145, -46, 118, -20, -84,-137, -83,-152,-157,-155; /I: I=-31; MI=0; MD=-79; IM=0; DM=-79; /M: SY='G'; M= -67,-155, 22, 19,-159, 62, -47,-159, 45,-156, -16, 35,-144, 51, 10, -82,-138,-155,-155,-147; /M: SY='T'; M= -5,-146, -68,-147, 8, -71,-144, 33,-145, 49, -17, -95, -72, -69, -69, 1, 62, -34,-147, 23; /I: I=-28; MI=0; MD=-70; IM=0; DM=-70; /M: SY='N'; M=-141, -5, 72, -61,-158, -70, -62,-156,-127,-160,-150, 114,-148, 32,-135,-125,-129,-157,-173,-148; /M: SY='C'; M=-139, 160,-158,-158,-149,-154,-158,-156,-154,-147,-147,-145,-169,-162, -73,-141,-139,-144,-178,-159; /M: SY='G'; M= -9,-152, -77, -66, -83, 89, -60,-159, 13, -94, -66, -54,-145, -18, 20, 2, -24,-102,-152,-149; /M: SY='A'; M= 65,-147, -60, 17, -49, 18, -15, -31, 6, -22, -26, -80,-144, 27, -16, 11, -39, -62,-153, -68; /M: SY='C'; M=-139, 161,-159,-159,-149,-154,-159,-156,-154,-146,-147,-145,-169,-162,-161,-141,-139,-143,-179,-160; /M: SY='G'; M=-127,-154, -81, -92,-160, 108,-147,-167,-145,-163,-152, -45,-146, -52, -49,-127,-145,-105,-152,-155; /I: I=-42; MD=-106; /M: SY='Y'; M= -32, -19,-145, 20, 45,-155, 23, -65, -93, -52,-134,-102, -73, -15, -16, -9, -90, -54,-125, 107; D=-42; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='P'; M= 19,-155, 25, 22, -58, -12, -11,-149, 3, -90,-144, -19, 79, -5, -5, 9, -91, -46,-152, 15; /M: SY='T'; M= -65,-145, 27,-135, -82, 38,-138,-149, -91,-106,-145, 45,-142, -78, -36, 53, 78,-143,-162,-146; /M: SY='C'; M=-139, 161,-159,-159,-149,-154,-159,-156,-154,-146,-147,-145,-169,-162,-161,-141,-139,-143,-179,-160; /M: SY='R'; M= 14,-153, -12, 10, -36, -63, 1, -95, 17, -2, 54, -55, -88, 1, 68, -16, -62, -92, -13, 29; /M: SY='A'; M= 55, -60, 42, 51,-156, -1,-138, -60, -88,-118,-144, -34, 11, 30, -84, 2, -4, -55,-158,-148; /M: SY='F'; M= -76, -41,-158,-152, 94,-113, -41,-123, -11, 24, 84, -69,-158,-147, -72,-148,-142,-129,-127, 59; /M: SY='A'; M= 97,-140,-144, -90,-150, -55,-146, -84, -64, -47, -53, -69,-145,-136, -44, -1, -23, -15,-154,-147; /M: SY='E'; M= 19,-151, -35, 56, -87, -41, -52, 7, 35, -51, 2, -25, -72, 6, 17, -16, 4, 5,-155, -56; /M: SY='A'; M= 86,-145, 40, -27,-154, -60, -34,-147, 34, -71, -32,-132,-144, -30, -33, -39,-132,-137,-156,-146; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='I'; M= -94, -24, -86, -49, -62,-162,-152, 71, -20, 35, 35, -74,-154,-146, -32,-147,-135, 56, -44, -38; /M: SY='V'; M= 32, -40, -76, -97, 22, -98, -64, 27, -68, 22, -4,-149,-153, -65, -66, -46, -36, 58,-145, 38; /M: SY='N'; M= 12, -59, 8, 24,-152, -72, -9,-102, 42, -29,-140, 61,-145, 44, 34, -27, -8,-104, -49, -84; /M: SY='G'; M= -61,-154, -35, -37,-158, 94, -13,-162, -7,-159,-149, 5, -77, -7, 0, -40, -39, -70,-154,-151; /I: I=-31; MI=0; MD=-79; IM=0; DM=-79; /M: SY='E'; M= -27, -60, 25, 64, -94, -42, -19, -43, 25, 10, 3, -10, -47, -1, 18, -16, -64, -59,-156, -26; D=-31; /I: I=-31; DM=-79; /M: SY='A'; M= 65, -37, -15, -5, -29, -74, -60, -22, 5, -77, -19, 45, -82, -20, -35, -11, -2, 1,-154, -8; /M: SY='E'; M= 2,-152, 23, 39, -65, -22, -5, -40, 35, -55, -56, 17, 23, 5, 16, 8, 18, -59,-158,-144; /M: SY='P'; M= -31, -68, -68, -15, -41, -26, -31, 45, -2, 25, 13, -72, 60, -85, -11, -41, -45, 15, 10, -30; /M: SY='N'; M= -26, -43, 51, 47, -82, -12, -31, -95, 18,-111, -71, 58, -3, -29, -47, 12, 8, -41, -40, -34; /M: SY='M'; M= -14, -44, 49, -5, -39, -8, -60,-144, 12, -21, 61, 56, -29, 22, 22, -26, -70,-107, -30, -16; /I: I=-29; MI=0; MD=-75; IM=0; DM=-75; /M: SY='C'; M= -89, 160,-158,-158,-149,-154,-158,-155,-154,-146,-146,-145,-169,-162,-161,-141, -71,-143,-178,-159; /I: I=-33; MI=0; MD=-84; IM=0; DM=-84; /M: SY='P'; M= 9, -53,-148, -76, -64,-150, -2, 22, -15, -5, 8, -88, 74, -28, -13, -46, 6, 45,-155, -47; /M: SY='P'; M= -9,-153, -22, -91, 33,-113, 42, -13, -99, -6, 10, -33, 79, -73, -39, -11, 3, 14,-148, 20; /M: SY='Y'; M= -51, -29, -71, -35, -2, 41, -23, -11, -2, 33, 29, -28, -72,-138, 7, -7, -83, -44, 7, 57; /M: SY='M'; M= -46,-150, -16, 0, -10, 41, -21, -7, 7, 9, 53, 26,-147, 15, -71, 7, 0, -51,-151, -11; /M: SY='R'; M= 0,-153, 20, 22,-150, -46, -61, -13, 33, -31, -13, -5, 7, 21, 53, -10, 3, -31,-156, -83; /M: SY='D'; M= 3,-154, 60, 59, -83, -49, -25, -26, 13, -27,-143, 10, 29, 13, -16, -24, -57, -89,-160,-146; /M: SY='V'; M= -39,-149, -41, 17,-139, -29,-141, 7, 23, 23, 20, -9,-147, 6, 19, 3, 13, 32,-155, -78; /M: SY='V'; M= 36, -43,-145, -6, -12, 4, -55, 18, -11, -1, 17, -14, -71, -39, -45, -25, -40, 37, -50, 29; /M: SY='E'; M= 9, -57, -2, 49, -86, -68, -8, 21, 19, -8, -57, -3, -32, 24, -13, 9, -9, 0,-157,-142; /M: SY='K'; M= 36, -19, 9, 29, -91, -36, -17, -58, 36, -45, -15, -8, -49, 18, 23, 4, -2, -14, -27,-143; /M: SY='I'; M= -49, -31, -18, 14, -59, -54,-143, 42, 17, 39, -11, 18,-150, -12, -14, -51, -65, 31,-154, -63; /M: SY='A'; M= 35, -76, 2, -7, -67, 27, -3, -29, 15, -14, -67, 29, -77, -16, 5, 16, -19, -35,-154, -10; /M: SY='E'; M= -3,-151, 16, 50, -64, -8, -31, -38, 23, -52,-142, 43, -49, 32, -5, 24, -14, -43,-157, -68; /M: SY='K'; M= 26, -45, -84, 17, -48, -29, 8, 24, 28, 8, -24, -29, -4, -27, 4, -43, 9, -2, -41, -10; /M: SY='L'; M= 1,-148, -86, -48, -68, -79, -29, 31, -67, 58, 50, -19, -30, 6, -40,-101, -41, 26,-152, -41; /M: SY='Q'; M= -9, -47, -49, 20, -31, 25, -36, 4, 32, -3, 12, 28, -4, 34, -36, -8, -37, -26,-153, -77; /M: SY='E'; M= -3,-151, 8, 52, -65, -20, -36, -5, 23, -12, -49, -5, 3, 15, -12, -58, 26, 2,-156, -50; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 121 in 121 different sequences |
| Number of true positive hits | 121 in 121 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Archaea, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Feature key [info] | DOMAIN |
| Feature description [info] | 4Fe-4S |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
121 sequences
ACDG1_METMA (Q8PZ09), ACDG1_METTE (Q50539), ACDG2_METMA (Q8PV87), ACDG2_METTE (Q9C4Z0), ACDG_ARCFU (O29871), ACDG_METAC (Q8TH44), ACDG_METJA (Q57576), ACDG_METKA (Q8TXF1), ACDG_METTH (O27748), ACSC_MOOTH (Q07340), MOBB_METJA (Q58720), RNFB_ACEWD (H6LC27), RNFB_AERHH (A0KLJ3), RNFB_AERS4 (A4SNP6), RNFB_ALCBS (Q0VP40), RNFB_ALIF1 (Q5E6B7), RNFB_ALIFM (B5FCN4), RNFB_ALISL (B6EGH6), RNFB_ALKEH (Q0AAG8), RNFB_AROAE (Q5P1B1), RNFB_AZOSB (A1K5F2), RNFB_BUCA5 (B8D8R5), RNFB_BUCAI (P57214), RNFB_BUCAP (Q8KA20), RNFB_BUCAT (B8D719), RNFB_BUCBP (Q89AW9), RNFB_CERS1 (A3PRP4), RNFB_CERS4 (Q3IXC5), RNFB_CITK8 (A8AH09), RNFB_CLOLD (D8GR71), RNFB_CROS8 (A7MMM3), RNFB_EDWI9 (C5BDE6), RNFB_ERWT9 (B2VEQ2), RNFB_HAEDU (Q7VNT5), RNFB_HAEI8 (Q4QJQ7), RNFB_HAEIE (A5UBJ1), RNFB_HAEIN (P71396), RNFB_HAHCH (Q2SKU5), RNFB_KLEP3 (B5XWQ0), RNFB_MAGMM (A0L5G7), RNFB_METAC (Q8TSX9), RNFB_PASMU (Q9CNP1), RNFB_PECAS (Q6D4W3), RNFB_PECCP (C6DH16), RNFB_PSEA7 (A6V1T8), RNFB_PSEA8 (B7UWJ3), RNFB_PSEAB (Q02QX9), RNFB_PSEAE (Q9HYB9), RNFB_PSEMY (A4XS52), RNFB_RHOCA (P0CZ14), RNFB_RHOCB (D5ARZ0), RNFB_SERP5 (A8GE01), RNFB_SHEAM (A1S6N0), RNFB_SHELP (A3QEN5), RNFB_SHEON (Q8EE80), RNFB_SHEPA (A8H537), RNFB_SHEPW (B8CM57), RNFB_SHESA (A0KX80), RNFB_SHESH (A8FUX9), RNFB_SHESM (Q0HIH9), RNFB_SHESR (Q0HVF6), RNFB_SODGM (Q2NSZ6), RNFB_STUS1 (A4VIV5), RNFB_THIDA (Q3SHB7), RNFB_TOLAT (C4LEP6), RNFB_VIBA3 (B7VLT8), RNFB_VIBC1 (A7MVC6), RNFB_VIBC3 (A5F2R3), RNFB_VIBCH (Q9KT87), RNFB_VIBCM (C3LTR4), RNFB_VIBPA (Q87MX3), RNFB_VIBVU (Q8D889), RNFB_VIBVY (Q7MM82), RNFB_YERPA (Q1C7K2), RNFB_YERPE (Q8ZEC9), RNFB_YERPG (A9R8U7), RNFB_YERPN (Q1CIY8), RSXB_ECO24 (A7ZM88), RSXB_ECO27 (B7URW9), RSXB_ECO45 (B7M9Y2), RSXB_ECO55 (B7L5I1), RSXB_ECO57 (P58323), RSXB_ECO5E (B5Z462), RSXB_ECO7I (B7NU05), RSXB_ECO81 (B7MV10), RSXB_ECO8A (B7M0I5), RSXB_ECOBW (C4ZY91), RSXB_ECODH (B1XF93), RSXB_ECOHS (A8A0H1), RSXB_ECOK1 (A1ABH3), RSXB_ECOL5 (Q0THJ9), RSXB_ECOL6 (Q8FH96), RSXB_ECOLC (B1IQC6), RSXB_ECOLI (P77223), RSXB_ECOLU (B7NB82), RSXB_ECOSE (B6IB63), RSXB_ECOSM (B1LEQ8), RSXB_ECOUT (Q1RBG8), RSXB_ESCF3 (B7LQP2), RSXB_SALA4 (B5F6I9), RSXB_SALAR (A9MRW7), RSXB_SALCH (Q57PH9), RSXB_SALDC (B5FIE6), RSXB_SALEP (B5QV01), RSXB_SALG2 (B5RAK1), RSXB_SALHS (B4THD5), RSXB_SALNS (B4T595), RSXB_SALPA (Q5PIC0), RSXB_SALPB (A9N024), RSXB_SALPC (C0Q507), RSXB_SALPK (B5BKB1), RSXB_SALSV (B4TV18), RSXB_SALTI (Q8Z6R0), RSXB_SALTY (Q8ZPM1), RSXB_SHIB3 (B2U2C7), RSXB_SHIBS (Q320Y5), RSXB_SHIDS (Q32FE5), RSXB_SHIFL (Q83KY6), RSXB_SHISS (Q3Z1Y3), Y119_METJA (Q57583), Y2201_ARCFU (O28082)» more
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| PDB [Detailed view] |
3 PDB
4DJD; 4DJE; 4DJF |