PROSITE entry PS51643
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS51643 |
| Entry name [info] | HD_CAS3 |
| Accession [info] | PS51643 |
| Entry type [info] | MATRIX |
| Date [info] |
01-APR-2012 CREATED;
10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51643 |
| Associated ProRule [info] | PRU00974 |
Name and characterization of the entry
| Description [info] | HD Cas3-type domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=184; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=179; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.5043204; R2=0.0072739; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=33753.0000000; R2=0.0000000; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=1443; H_SCORE=33753; N_SCORE=13.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=550; H_SCORE=33753; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-41; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='D'; M= 5, -10, 36, 25, -67, 16, -18, -52, 22, -24, -87, 11, 7, -28, 0, 12, -25, -53, -5, 15; /M: SY='S'; M= 3, -91, 30, 23, -42, 18, -21, -48, 21, -48,-113, 6, 1, -10, -12, 44, 2, -48, -26,-109; /M: SY='H'; M= -28, -73, 8, 7, -30, 30, 56, -57, 20, -49, -32, 39, 7, -14, -16, 9, -4, -74, -7, 14; /M: SY='P'; M= -12, -38, 26, 9, -97, -3, -35, -47, 16, -90, -64, 7, 64, 19, 31, -14, -5, -18,-225, -12; /M: SY='W'; M= -20, -34, 5, 14, -5, 11, -3, -21, 7, -68, -36, -8, 28, -26, -13, -32, -19, -57, 110, 37; /M: SY='H'; M= -67,-225, -92, 52, -84,-117, 86, -32, 20, -22, -72, -62,-214, 79, -20, -98, -29, -4,-223, 12; /M: SY='T'; M= -91,-116, -58, -52, -24, -61, -45,-119, -69, 30,-107, -55, 67, -43, -6, 31, 70,-119,-223, -2; /M: SY='L'; M= -50,-217,-231,-224, -12,-120,-216, 4,-224, 90, -41,-107, -98,-218,-222,-221,-209, -12, 9, -1; /I: I=-7; MD=-18; /M: SY='E'; M= 2, -36, -14, 29, -42, -91, -27, 5, 15, -2, -57, -34, 10, 10, 5, -3, -7, 6, 14, -1; D=-7; /I: I=-7; MD=-18; /M: SY='E'; M= -5, 22, 60, 64, -60, -51, -18,-104, -38, -74, -92, -24, -99, 25, -31, -40, -26, -61, -13, 19; D=-7; /I: I=-7; MD=-18; /M: SY='H'; M=-221,-233,-205,-205,-219,-223, 155,-238,-210,-220,-205,-194,-221,-199,-204,-210,-219,-237,-255,-188; D=-7; /I: I=-7; MD=-18; /M: SY='L'; M= -30, 38,-223,-138,-129, -86,-118, -5,-219, 58, 21, -13,-226, -34,-222, 28, 36, -19,-230,-211; D=-7; /I: I=-7; MD=-18; /M: SY='L'; M= -8, -68, 5, 29, -25, -76, -17, -16, 5, 34, -15, -5,-222, 20, 5, -15, -28, -50, -8, -36; D=-7; /I: I=-7; MD=-18; /M: SY='D'; M= -15,-125, 76, 21, -78, 15, -29, -79, -27, -24,-127, 42,-219, -20, -11, -21, -59,-122, -48,-219; D=-7; /I: I=-7; MD=-18; /M: SY='V'; M= -10, -7,-127,-223,-209,-227,-229, -48,-221, -17, -32,-127,-225,-223,-225, -19, 49, 86,-237,-215; D=-7; /I: I=-7; MD=-18; /M: SY='A'; M= 68, -63,-220, -52, -75, -1, -84, -18, -14, 13, -32, -68,-222, -47, -31, -12, -52, -20, -30, -10; D=-7; /I: I=-7; MD=-18; /M: SY='A'; M= 43, -7, 9, 43, -90, -63, -22, -41, 21, -96, -48, 20,-219, 4, -1, -35, -38, -83, -48, -29; D=-7; /I: I=-7; MD=-18; /M: SY='V'; M= 10, 29,-138, -12, -44, -93,-220, 1, -81, 13, 2, 0,-229, -25, 3, -69, -57, 43, -3, 23; D=-7; /I: I=-7; MD=-18; /M: SY='A'; M= 66, 22,-228,-223, 21, -6,-224, -55,-141, -6, 28,-122,-228,-221,-226, -39, -44, -12, -5, -24; D=-7; /I: I=-7; MD=-18; /M: SY='E'; M= -27, -57, -12, 49, -82, -14, -47,-142, 5, -33, -33, -13,-229, -37, 36, -53, -60,-126, -9, -15; D=-7; /I: I=-7; MI=0; MD=-18; IM=0; DM=-18; /M: SY='R'; M= -11, -50, -70, -23, -45, -88, -31, -12, -19, -11, -47, -54, -76, -13, 16, -55, -49, -26, -44, -51; D=-7; /I: I=-7; DM=-18; /M: SY='R'; M= -18, -45, -34, -62, -36, -59, -24, -30, 13, -17, -26, -20, -37, -3, 18, -26, -41, -65, -88, -84; D=-7; /I: I=-7; DM=-18; /M: SY='K'; M= -23, -67, -22, -19, -35, -85, -39, -4, 9, -3, -19, -13, -56, -21, 4, -30, -33, -44, -18, -16; D=-7; /I: I=-7; DM=-18; /M: SY='L'; M= -22, -57, -49, -6, 11, -65, -21, 1, -10, 13, -59, -32, -13, -10, -7, -21, -50, -16, -3, -44; D=-7; /I: I=-7; DM=-18; /M: SY='L'; M= 17, -29, -21, -8, 0, -72, -70, -14, -17, 18,-104, -43, -46, -14, -8, 11, -50, -55, -1, -21; D=-7; /I: I=-7; DM=-18; /M: SY='A'; M= 17, -20, 0, 2, -25, -18, -25, -45, 3, -15, -82, -3, -33, -28, 12, 4, -41, -24, -85, -26; D=-7; /I: I=-7; DM=-18; /M: SY='R'; M= 6, -12, -16, 8, -9, -21, -47, -17, -13, 4, -4, -35, -35, 1, 9, -5, -26, -28, -10, 8; D=-7; /I: I=-7; DM=-18; /M: SY='L'; M= -8, -54, 2, 1, 3, 4, -47, -6, -2, 15, -28, 4, -5, -2, -3, 9, -9, -55, 8, -43; D=-7; /I: I=-7; DM=-18; /M: SY='F'; M= -17, -29, -6, 6, 39, 19, -10, -1, -26, -3, -49, 8, -6, -26, -11, -11, -47, -30, -17, 18; D=-7; /I: I=-7; DM=-18; /M: SY='A'; M= 23, 17, -10, 10, -20, 11, -34, 14, -33, 8, 4, -25, -7, -14, -43, -14, -14, -30, 12, -24; D=-7; /I: I=-7; DM=-18; /M: SY='D'; M= -20, -60, 33, 25, -15, 1, -33, -27, -15, 4, -45, 19, 5, -21, -13, 6, 1, -30, -73, -20; D=-7; /I: I=-7; DM=-18; /M: SY='P'; M= -10, -65, 23, 27, -35, -8, -81, -15, 21, -29, -53, 2, 29, -9, 4, 3, -14, -21, 6, -29; D=-7; /I: I=-7; DM=-18; /M: SY='E'; M= -27, -64, 32, 62, 21, -7, -15, -17, 5, -57, -83, -8, 26, 0, -32, 0, -42, -59, -22, -57; D=-7; /I: I=-7; DM=-18; /M: SY='E'; M= -25,-107, 35, 37, -21, 21, -6, -16, 7, -11, -47, -1, -22, 15, -3, -9, -14, -10, -22, -66; D=-7; /I: I=-7; DM=-18; /M: SY='L'; M= 20, -38, -5, -34, 41, -49, -66, 27, -55, 46, 10, -71,-136, -38, -93, -43, -43, 13, 11, -12; /M: SY='W'; M= -2, -32, -20, 24, -55, -5, -49, -3, 32, -20, -63, -67, -14, 16, 42, -1, -40, -21, 70, -19; /M: SY='E'; M= 12, -60, 37, 49, -52, -55, 3, -59, 17, -19,-110, 18, -25, 23, 26, 7, -24, -81,-226, -59; /M: SY='W'; M= 9, -23, -24, -76, -9, -75, -30, 25, -78, 53, 23, -56, -60, -28, -14, -35, -5, -13, 80, -32; /M: SY='L'; M= 38, -23,-132, -78, 12, 6, -88, 27,-217, 43, 0, -75,-222,-215, -94, -29, -21, 33, -77, -28; /M: SY='Y'; M= 16, 8, -49, 28, 22, -20, -37, -22, 20, -17, -15, -99, -59, -18, 35, -32, -21, -1, 10, 37; /M: SY='W'; M= -7, -28, -70, -38, 53,-144, -51, 26, -27, 46, -12, -24,-124, -45, -42, -64, -14, -2, 58, 17; /M: SY='A'; M= 69, 15,-220,-215, -2, -45,-104, 22,-215, 29, 8, -91,-126,-136,-218, -3, -8, -5, 0, -70; /M: SY='G'; M= 58, 54,-218,-218, -93, 59,-220, 19,-107, -9, -75,-209,-117,-214,-221, -55, -39, 9,-224, -83; /M: SY='L'; M= 31, -26, -75, -29, 22, -2, -81, -3, -35, 52, -8,-118,-223, -51, -12, -60, -86, -12, 23, 31; /M: SY='W'; M= -30, 27,-227,-222, 47, -66, -16, -17,-220, 62, 23,-103,-227,-111,-219, -37, -14, -24, 70, 41; /M: SY='H'; M=-217,-228,-200,-131,-215,-218, 159,-233,-205,-216,-201,-190,-217, -78,-199,-206,-215,-233,-250,-184; /M: SY='D'; M=-215,-228, 130,-178,-235,-212,-200,-233,-202,-232,-231,-182,-214,-201,-211,-203,-204,-230,-251,-218; /M: SY='I'; M= -29,-104, -53, -98, 45,-148, -96, 65,-149, 52, -27,-223,-132,-219,-140, -52, -60, 15, 39, -8; /I: I=-26; MI=0; MD=-67; IM=0; DM=-67; /M: SY='G'; M= -51,-223,-212,-223,-138, 111,-218,-237,-217,-233,-222,-198,-215,-214,-224,-132,-215,-230,-221,-225; /M: SY='K'; M=-210,-224,-202,-188,-226,-217,-205,-226, 121,-225,-213,-195,-210,-187,-171,-204,-126,-222,-219,-213; /M: SY='A'; M= 66, 20,-106,-114, 27, -40,-108, 19,-119, 7, -24, -92,-221, -65, -68, -17, -50, -4,-211, 49; /M: SY='T'; M= 8, -37, 24, -85,-131, -56, 41, -79, -71, -72,-120, 60,-213, -50, -31, 57, 63, -95,-233, -71; /M: SY='P'; M= -11, -16, 16, 24, -51, -66, -19, -31, -4, -32,-101, -58, 73, 0, 16, 22, 6, -21, -73, -53; /M: SY='Y'; M= 30, -49, -1, 17, 8, 18, 1, -36, -4, -30,-207, 11, -28, -3, 24, -11, -47, -47, -57, 40; /M: SY='F'; M=-222,-221,-234,-229, 125,-229,-108,-198,-224,-190, -59, -79,-232,-112,-222,-221,-143,-138, 78, 25; /M: SY='Q'; M= -78, -71, -59,-107,-122,-215,-196, -85, -89, -81,-204, -98,-214, 140, -92,-196,-100,-104,-220,-124; /M: SY='R'; M= 17, -13, 23, 35, -51, -31, -24, -32, 25, -49, -34, 31,-215, 35, 40, -14, -18, -83, -49, -36; /M: SY='Y'; M= -29,-107, -63, -60, -73, -58, -19, -84, 57, -17, 43, -21, -90, 31, 33, -32, -56, -71, 17, 83; /M: SY='L'; M= -34, -56, -58, -96, -24,-120, -96, 54, -13, 63, -12, -57, -58, -60, -10, -68,-207, 14, 1, -14; /M: SY='R'; M= -28, -38, -14, 13, -38, -9, -8, -75, 24, 1, 16, -3, 8, 23, 55, -14, -5, -46, 2, -30; /M: SY='G'; M= -1, -67, 13, 12, -53, 40, 3, -50, 28, -47,-115, 29, 0, 0, 2, 11, -10, -71, -17, -16; /I: I=-5; MD=-12; /M: SY='N'; M= 2, -23, 3, 10,-101, 23,-122, -33, 7, -20, -36, 44, -2, 8, -3, -12, -43, -54, 7, -34; D=-5; /I: I=-5; MD=-12; /M: SY='K'; M= -9, 3, 6, 9, -92, -14, -48, -33, 29, -42, -7, 17, -48, 7, -6, -11, -6, -44, 3, -36; D=-5; /I: I=-5; MD=-12; /M: SY='E'; M= -28, -81, 1, 15, -76, -2, -43, -66, 3, -56,-112, 13, -13, 5, -23, -20, -15, -82, -47, -49; D=-5; /I: I=-5; MI=0; MD=-12; IM=0; DM=-12; /M: SY='D'; M= -24, -84, -5, -7, -36, -30, -45, -56, -16, -44, -78, -27, -11, -11, -27, -30, -48, -69, -60, -9; D=-5; /I: I=-5; DM=-12; /M: SY='P'; M= -22,-110, -15, -18, -70, -38, -36, -41, 19, -58, -53, -11, 24, -69, 3, -28, -27, -32, -88, -51; D=-5; /I: I=-5; DM=-12; /M: SY='P'; M= -29, -49, -4, 12, -28, -28, -64, -48, -4, -25, -81, -54, 28, -11, -7, 12, -30, -47, -83,-120; D=-5; /I: I=-5; DM=-12; /M: SY='K'; M= -40,-233, -12, -3, -48, 16, -20, -38, 19, -19, -80, -16, 6, -12, 8, 9, -29, -32, -27, -30; D=-5; /I: I=-5; DM=-12; /M: SY='K'; M= -35, -42, 9, -5, -29, -9, -23, -25, 31, -20, -15, 9, 13, -13, 23, 5, -20, -29, -35, -10; D=-5; /I: I=-5; DM=-12; /M: SY='R'; M= -14, -41, -19, -24, -55, 14, -17, -15, 20, -42, -63, -3, 37, -30, 38, 20, -25, -29, -11, -13; D=-5; /I: I=-5; DM=-12; /M: SY='W'; M= -57, -56, 29, -1, -67, 14, -18, -33, 32, -31, -33, -10, 28, 16, 15, 17, -27, -36, 45, -12; D=-5; /I: I=-5; DM=-12; /M: SY='H'; M= -33, -60, -4, 26, 5, 27, 29, -84, 26, -12, -75, -5, 27, -26, 26, 0, -36, -55, -33, -3; /M: SY='Y'; M= -15, -45,-107, -33, 25, -53, -5, 30, -6, -21, -31,-132, 24, -53, -26, 6, 3, 38, 39, 42; /M: SY='R'; M= -65, -55, 40, -48, -50, -25, 29, -97, -36, -87,-213, 19, 54, -29, 80, -9, -32,-105, -96, -2; /M: SY='H'; M=-216,-228,-200,-201,-215,-218, 159,-233,-205,-216,-201,-190,-217,-194,-199, -80,-215,-233,-250,-184; /M: SY='E'; M= 41,-218, -7, 72,-138, 7, -75, -94, -84,-133, -71, 9, -36,-195,-125, 56, -40,-110, -32,-125; /M: SY='W'; M= -5, -35, -45, -29, 24, -67, -5, 21, -71, 25, -39,-105, -25, -46, -16, -2, 42, 10, 73, -2; /M: SY='L'; M= 47, -73,-137, -18, -16, -50, -62, 33, -72, 50, -57,-125, -34, -59, -95, -35, -89, 14, 15, -7; /M: SY='S'; M= -49,-215,-206,-128,-224, 69,-106, -81,-209,-163,-218,-194,-131,-203,-214, 95, -14,-130,-226,-217; /M: SY='A'; M= 73, -10,-216, -47, -28, 1, -51, -44,-139, 19, -37,-210, -46, -3,-105, -1, -27, -3, -52, 4; /M: SY='W'; M= 29, -13, -88, -36, 29, -60, -59, 6, 0, 28, -47, -91, -11, 0, 22, -51,-135, -2, 51, 32; /M: SY='F'; M= 0, -35, -78, -44, 62,-126, -28, 24,-134, 51, -3,-221,-132,-137,-106, -68, -33, -3, 52, 36; /M: SY='W'; M= 28, -18,-136,-109, 42, -58,-218, 20,-219, 48, -28,-220,-224,-217,-220, -30, -15, 26, 52, 11; /I: I=-4; MD=-11; /M: SY='Y'; M= -2, -42, -6, -6, 4, -66, -24, -48, -30, -5, -3, 2, 1, 26, -9, -22, -41, -46, 46, 46; D=-4; /I: I=-4; MD=-11; /M: SY='Y'; M= 22, -79, 11, 10, -32, -84, 8,-111, -27, -61,-225, -33, -81, 13, 10, -23, -60, -63, -52, 27; D=-4; /I: I=-4; MI=0; MD=-11; IM=0; DM=-11; /M: SY='W'; M= -55, -47, -16, -13, -8, -48, -32, -29, -10, -5, -71, -48, -12, -37, -51, -18, -72, -57, 11, -6; D=-4; /I: I=-4; DM=-11; /M: SY='W'; M= -42, -44, -5, -4, -4, -43, -13, -11, -20, 1, -63, -13, -13, -30, -35, -4, -35, -43, 12, -9; D=-4; /I: I=-4; DM=-11; /M: SY='L'; M= -25, -16, -49, 2, -38, -39, -5, -21, 2, 15, -78, 4, 2, -14, -11, -15, -24, -58, -3, -29; D=-4; /I: I=-4; DM=-11; /M: SY='E'; M= -29, -56, 18, 18, -58, -49, -29, -40, 8, -9, -52, 9, -6, -10, -7, 15, -10, -44, -2, -27; D=-4; /I: I=-4; DM=-11; /M: SY='E'; M= -19, -22, 14, 26, -9, -23, -22, -31, 3, -17,-109, 13, 19, 17, -2, 1, -40, -44, -11, -52; D=-4; /I: I=-4; DM=-11; /M: SY='W'; M= -22, -29, -2, 14, 0, -14, -11, -31, 22, 13, -46, 15, -26, 0, -2, -6, -8, -49, 23, -36; D=-4; /I: I=-4; DM=-11; /M: SY='G'; M= -21, -13, 20, 9, -3, 27, -22, -33, 15, -19, -96, 1, 9, -28, 5, 1, -21, -43, 11, -58; D=-4; /I: I=-4; DM=-11; /M: SY='W'; M= -15, -6, 6, 8, 17, -16, 4, -13, 14, 15, -43, -7, -30, 1, -29, 2, -28, -46, 51, 16; D=-4; /I: I=-4; DM=-11; /M: SY='D'; M= -26, -39, 47, 14, -24, -15, -31, -50, -4, 10, -36, 15, 24, 4, -21, 17, -37, -41, 16, -2; D=-4; /I: I=-4; DM=-11; /M: SY='P'; M= 0, -85, 4, 38, -14, -1, -9, -53, 27, -29, -69, 20, 42, -8, 17, -4, -19, -70, -19, -37; /M: SY='E'; M= -25, -60, 16, 38, -5, 2, 8, -12, -1, -12, -40, -5, 37, 2, 7, -8, -15, -19, -26, -13; /M: SY='L'; M= -2, -18, 21, 8, 16, -40, -4, -4, -50, 38, -4, -18, -39, -31, -47, -33, 2, 15, 9, 2; /M: SY='A'; M= 46, -18, -13, -74, -3, -4, -36, -2, -2, 6, -6, -15, 12, -16, 18, -12, -27, -48, 21, 1; /M: SY='R'; M= -25, -54, 25, 26, 3, -57, 7, -21, 11, 13, -2, 1, 3, 23, 29, -25, -33, -37, -20, 6; /M: SY='W'; M= 20, -57, -51, -58, -4, -38, -39, 32, -77, 46, -3, -39, 7, -35, -30, -24, -29, 6, 54, -20; /M: SY='W'; M= 13, -48,-225, -78, -1, -34, -70, 44,-219, 42, -9, -43,-147, -64,-221, -16, -45, 48, 57, -87; /M: SY='A'; M= 54, -24, -81, -55, 26, -7,-104, -4, -62, 16, 16,-126, -73, -35, -37, 13, -6, -15, 1, 23; /M: SY='W'; M= 9, -41, -47, -18, 13, -81, 26, -31, -56, 22, -11, -10, -54, 5, -1, -22, -11, -23, 74, 69; /M: SY='A'; M= 64, 47, -59,-119, -56, -40,-218, 17,-215, 29, -18, -79, -22,-129,-219, -3, -23, 20,-225,-211; /M: SY='I'; M= -17, -57,-229,-122,-129,-152,-229, 87,-222, -19, -50,-222, -66,-221,-225, -53, -34, 70,-226,-207; /M: SY='A'; M= 52, -22,-109,-106, -21, 21, -65, -3, -26, 31, 27, -67,-219, -59, -21, -10, -18, -2, -39, -13; /M: SY='G'; M= 17, -3, -71,-119, -23, 53, 7,-111, -1, -23, -55, -11,-216, -43, 23, 42, 15,-152, -7, -10; /M: SY='H'; M=-216,-228,-200,-201,-215,-218, 159,-233,-205,-216,-201,-190,-217,-194,-199, -58,-214,-232,-250,-184; /M: SY='H'; M=-149,-228,-201,-201,-214,-139, 159,-232,-206, -80,-200,-190,-217,-195,-200,-206,-215,-232,-250,-184; /M: SY='G'; M= -13,-221, -54, -31,-222, 78, -26,-158, 1, -88,-216, -10,-215, -34, 25, 28, 7,-221, -8, -23; /M: SY='R'; M= -13,-222, 16, -74, -34, 29, 17, -37, 22, -5, -25, 18, 9, -28, 46, -8, -37, -41, -25, 7; /M: SY='P'; M= -37, -32, -46, -43, 33, -22, -29, 7, -65, 55, 1, -63, 62, -72, -41, -51, -61, -26, 1, -30; /M: SY='P'; M= -30, -46, 14, -7, -28, -22, -15, -1, 6, -15, -11, -21, 62, -15, 31, -8, -5, -6, -46, -1; /M: SY='D'; M= -43, -19, 63, 2, -24, -25, -48, -41, -8, -19, -18, 48, 27, -21, -15, 17, -9, -36, -46, -22; /M: SY='P'; M= -15, 18, 17, -2, 25, -8, -6, -3, -24, 14, -21, -9, 27, -30, -11, -5, -33, -2, 26, -2; /M: SY='D'; M= -15, -69, 37, 17, -19, 9, -12, -7, -19, 8, 2, 16, -22, 7, -15, 13, -11, -18, -39, -10; /M: SY='D'; M= -27,-109, 49, 29, -31, -1, -12, -50, 8, -23, -26, 27, 13, 2, 2, 2, 0, -47,-223, 13; /M: SY='E'; M= -12, -29, 25, 26, -2, -30, 5, 3, -1, 4, -22, 10, 18, 8, -7, -1, -35, -25, -43, 17; /M: SY='D'; M= -24, -3, 30, 10, 5, -3, -18, -7, 5, 2, -36, 10, -25, -25, 18, 14, -14, -12, -23, 4; /M: SY='D'; M= -19, -82, 29, 22, -7, 1, -1, -3, -13, -12, -57, 13, 21, -14, 5, 14, -5, -20, -11, 5; /I: I=-6; MD=-15; /M: SY='D'; M= -1, -59, 24, 9, -25, -12, -25, -7, 7, 7, -41, 12, 22, 2, 7, 5, -29, -29, -24, -28; D=-6; /I: I=-6; MD=-15; /M: SY='W'; M= -10, -37, 24, 24, -11, -16, -13, -26, -1, -8, -37, 6, 8, -11, 11, -1, -10, -38, 25, -28; D=-6; /I: I=-6; MD=-15; /M: SY='D'; M= 7, -48, 15, 14, 4, -21, -29, -29, 6, -18, 5, -13, 8, -28, -4, 0, -44, -31, -56, 6; D=-6; /I: I=-6; MD=-15; /M: SY='P'; M= -12, -9, 14, 1, -9, -28, -19, -48, -11, -25, -40, -6, 21, -14, -15, 5, -40, -28, -54, 21; D=-6; /I: I=-6; MD=-15; /M: SY='D'; M= -28,-101, 20, 5, -10, -27, -52, -36, -37, -5, -62, -15, 16, -33, -6, -17, -6, -68, 1, -11; D=-6; /I: I=-6; MD=-15; /M: SY='D'; M= -36, -58, 1, -1, -44, -19, -60, -15, -19, -17, -76, -17, -5, -49, -16, -9, -20, -31, 1, -2; D=-6; /I: I=-6; MD=-15; /M: SY='D'; M= -45, -73, 9, -5, -53, -15, -87, -45, -20, -32, -72, -7, 2,-118, -1, -29, -38,-100, 3, -28; D=-6; /I: I=-6; MI=0; MD=-15; IM=0; DM=-15; /M: SY='W'; M=-162, -18, 34, -73, -5, -91, -48, -89,-102, -14, -96, -25, -72, -36, -68,-100, -86,-243, 112, -51; D=-6; /I: I=-6; DM=-15; /M: SY='K'; M= -27, -13, -25, 10, -43,-108, -55, -10, 15, -87, -79, -44, -17, 14, 10, -26, -58, -39,-245, -47; D=-6; /I: I=-6; DM=-15; /M: SY='E'; M= 4,-240, -11, 29,-244, -33, -66, -99, 15,-110, -56, -14, -28, 24, -29, -12, 1, -80,-246,-235; D=-6; /I: I=-6; DM=-15; /M: SY='A'; M= 30, -43, -27, -7, -26, -57,-228, 16, -27, -33, -23, -36,-138, 6, -61, -36, -28, 1, -33, -26; D=-6; /I: I=-6; DM=-15; /M: SY='R'; M= 17, -41, -16, -59, -44,-130, 2, 6, -18, 0,-106, -67, -27, 10, 37, -47,-112, -67, 28, 7; D=-6; /I: I=-6; DM=-15; /M: SY='E'; M= -5,-114, 27, 37,-106, -81, -59, -59, 32, -87, -65, 17,-222, 32, 31, -29, -39, -46, -39, -90; D=-6; /I: I=-6; DM=-15; /M: SY='E'; M= 1, -43, 39, 53, -91, -69, 5, -66, 10, -78,-103, 14, -70, 10, 4, -30, 6, -39, -88, -94; D=-6; /I: I=-6; DM=-15; /M: SY='F'; M= -59, -27, -76, -35, 58,-105, 31, 10, -50, 39, 7,-127,-105, 6, -94, -67, -28, -13, 39, 28; D=-6; /I: I=-6; DM=-15; /M: SY='L'; M= 24, -38, -36, -31, 17, -84, -15, 35, -14, 45, -10,-125,-223, -57, -53, -35, -31, 19, -41, -43; D=-6; /I: I=-6; DM=-15; /M: SY='E'; M= -23, -22, 36, 52,-224, -12, -15,-115, 30, -31, -65, 21, -11, 41, 37, -33, -39, -76,-227,-110; /M: SY='R'; M= 2,-223, 35, 44, -19, -21, -1, -67, -10, -25, -61, 0, -71, -21, 53, -25, -14, -38, 46, 1; /M: SY='I'; M= 17, 0,-131,-221, -13, -41,-123, 48, -68, 45, 42,-220,-223,-217,-151, -63, -32, 40, 35, -35; /M: SY='K'; M= 10, -60, -4, 26, -7, -82, -9, -34, 38, 18, -36, 0, -9, -3, 17, 1, -28, -29, 24, -56; /M: SY='E'; M= 8, -56, 44, 53,-225, -34, -8,-116, 38, -93,-214, 10, -58, 25, 9, 13, -11, -41,-228, -73; /M: SY='L'; M= -6, 1, -4, 21, 1, -39, 26, 17, -22, 30, -26, -11, -53, 9, -14, -57, -9, -5, 29, 7; /I: I=-8; MD=-20; /M: SY='W'; M= -2, 5, -17, -36, 42, -39,-214, 9, -30, 37, -99, -8, -46,-213, -34, -9, 0, -15, 60, 19; D=-8; /I: I=-8; MD=-20; /M: SY='P'; M= -59,-125, 27, 19, -47, 34, -32, -38, 9, -18, -83, 28, 38, 32, -69, -10, -31, -79, -33, -44; D=-8; /I: I=-8; MD=-20; /M: SY='E'; M= 1, -57, 19, 20, 13, -63, -12, 1, -4, -19,-209, 1, -1, 4,-111, 9, -10, -12, -21, 15; D=-8; /I: I=-8; MD=-20; /M: SY='W'; M= -32,-125, 19, -7, -6, -32, -41, -3, -26, 7, -14, 1, 14, -13, -61, -5, 1, -40, 50, 15; D=-8; /I: I=-8; MD=-20; /M: SY='D'; M= -15, -51, 13, 2, -13, 2, -25, -2, -30, 7, -49, -16, 5,-108, -9, -14, -36, -60, -6, -8; D=-8; /I: I=-8; MD=-20; /M: SY='Y'; M= -16, -59, -14, -14, -60, -14, -72, -11, -14, -8, -84, -8, 0, -26, -13, -22, -18, -33, -12, 20; D=-8; /I: I=-8; MD=-20; /M: SY='E'; M= -63, -29, -13, 21, -64, -42, -41, -45, 3, -8,-100, -69, -32, -14, -27, -20, -56, -27, -11, 6; D=-8; /I: I=-8; MD=-20; /M: SY='W'; M= -30, -63, -13, -26, -54, -38, -32, 3, -14, -30, -25, -46, -24, -22, -22, -43, -27, -43, 10, -15; D=-8; /I: I=-8; MI=0; MD=-20; IM=0; DM=-20; /M: SY='W'; M= -90,-235, -3, 40, -21, -71, 1, -52, -41, -32, -96, 21, -38, -5, -49, 16, -43, -6, 51, 9; D=-8; /I: I=-8; DM=-20; /M: SY='W'; M= -41,-228,-226, -19, 9,-230,-121, 21, -44, 46, -10, -92, 43, -15, 12,-122,-214, -10, 69, -27; D=-8; /I: I=-8; DM=-20; /M: SY='P'; M= 1, -39, 20, 50, -61, -43, 19, -84, 10, -45, -48, 3, 56, 20, 25, -5, -46, -78,-226, -62; /M: SY='E'; M= -23,-225, 43, 57,-228, 15, -13,-228, 25,-225,-217, 13, 20, 3, 36, 6, -47,-223,-228,-217; /M: SY='I'; M= -61,-219,-131,-222, 32,-124, -60, 57, -76, 54, -29, -62, -45, -79, -52, -75, -25, 25,-212, 34; /M: SY='P'; M= -34, 6, 27, -6, -21, -6,-210, 4, 7, -12, -1, 7, 55, -25, -12, 13, 17, -39, -7, -93; /M: SY='L'; M= -13, -43, -2, 12, 11, -34, -25, 17, -30, 30, -30, -22, 15, -10, 18, 18, -3, -55, -22, -31; /M: SY='P'; M= -1, -80, 35, 32, -91, -37, -20, -25, 29, -26, -60, 1, 47, 15, 2, 14, -13, -62,-226, -57; /M: SY='D'; M= -14, -72, 44, 38,-110, -6,-206, -6, 1, -8,-208, -3, 3, 22, 0, 20, -30, -38, 15, -4; /M: SY='E'; M= 3,-222, 24, 27, 10, -22, -21, -12, 8, 8, -22, -2, 23, -17, 4, 8, -17, -92, 3, -7; /I: I=-7; MD=-19; /M: SY='W'; M=-217,-231, -41, 25, 7, -70, -74, -68, 33, 8, -94, 0, 10, 5, -76, 7, 0, -18, 37, -73; D=-7; /I: I=-7; MD=-19; /M: SY='W'; M= -68,-241, -8, 26,-152, -65,-101, -16, 17, -33, -55, 7, -19, 15, -39, 7,-100, -45, 47, -88; D=-7; /I: I=-7; MI=0; MD=-19; IM=0; DM=-19; /M: SY='W'; M= -41,-124, -6, -9, -30, -80, -88, -58, -3, -24,-106, -6, -10, -19, -14, -48, -40, -45, -2, -40; D=-7; /I: I=-7; DM=-19; /M: SY='R'; M= -22, -10, 8, -23, -53, -20, -65,-241, -29, -53, -55, 6, -3, -33, 10, -4, -53, -60, -59, -50; D=-7; /I: I=-7; DM=-19; /M: SY='F'; M= -52,-106, -14, 11, 38,-114, -29, -4, -37, -33, -29, -19, -54, -40, -5, -49, -39, -36, -5, -27; D=-7; /I: I=-7; DM=-19; /M: SY='Y'; M= -15,-126, -3, 7, -49, -78, -22, -73, -4, -25, -25, -42, -67, 7, 6, 9, -71, -55,-233, 36; D=-7; /I: I=-7; DM=-19; /M: SY='L'; M= -36, -61, 6, -56, 21, -2, 2, -24, -42, 24, -12, -35, -49, -49, -13, -61, -46, -71, 7, 7; D=-7; /I: I=-7; DM=-19; /M: SY='Y'; M= -23,-234, -50, -44, 18, -6, -26, -99, -8, -54, -47, -9, 22, -21, 14, 3, -51, -82, 50, 57; D=-7; /I: I=-7; DM=-19; /M: SY='W'; M= -13, -18, -45, -45, 50, -51, -86, -3, -23, 18, 14, -52, 15, -6, -3, -41, -24, -23, 53, -17; D=-7; /I: I=-7; DM=-19; /M: SY='F'; M= 9, 5, -35, -30, 43, -18, -39, -18, -14, 37, -28, -22, -85, -9, -10, -66, -44, -26, 25, 27; D=-7; /I: I=-7; DM=-19; /M: SY='Y'; M= 13, -1,-217, -58, 12, -25, -20, 8, -97, 26, -7, -41, -78, 7, -51, 9, 25, 12, 0, 51; /M: SY='W'; M= 11,-222, -58, -77, -40,-116, 24, 13, 2, 4, 1, -6, -33, 0, 59, -10, -39, 15, 66, -83; /M: SY='M'; M= -22, -63, -99, -66, 43,-103, 12, 3, -35, 45, 72,-138, -58, -25, -25, -53, -62, -28, 27, 53; /M: SY='L'; M= -60, -27,-126, -99, 12,-154, -48, 25,-110, 76, 13, -63, -57,-125,-112, -33, -68, 16, -3, -22; /M: SY='F'; M= 28, -46,-211, 13, 59,-119, -54,-206, 25, -12, -62, -31,-218, -40, -1, 5, 12, -33, -12, 54; /M: SY='S'; M= 19,-217,-208,-211,-142, 74, -53,-225, -89,-100,-116,-197, -87,-204, -1, 76, -36,-135,-225,-218; /M: SY='C'; M= 10, 70,-226,-102, 12,-126,-218, 25,-218, 62, 1, -81, -53,-216, -23, -29, -42, -1, -39, -93; /M: SY='L'; M= -53, -2,-143,-106, -72, -96,-218, -16,-222, 84, -40,-224,-135,-114,-221, -52, -10, 34,-222,-203; /M: SY='I'; M= -73, -52,-103,-133,-204,-124, 12, 58, -31, 2, 36, 6,-220, -31, 28, -5, 19, 47,-227,-115; /I: I=-26; MI=0; MD=-67; IM=0; DM=-67; /M: SY='D'; M= 16,-100, 66, -71, -27,-110, -74, -22, -30, 38, 27, -27,-219, -54, 6, -20, -12, 8, -40, -57; /M: SY='A'; M= 90, 67,-215,-210,-129, -33,-216, -34,-211, -52,-108, -61,-216,-208,-216, 32, -61, -90,-225, -85; /M: SY='D'; M=-215,-228, 129,-131,-235,-119,-200,-233,-113,-232,-230, -90,-127,-201,-210,-120,-204,-230,-249,-110; /I: I=-33; MI=0; MD=-84; IM=0; DM=-84; /M: SY='W'; M= -97,-230,-217,-209, 23,-114, 87, -80, 26,-109, -45, -60,-222, -20, 40, -48,-215, -50, 130, 50; /M: SY='L'; M= 13, -77,-105, -27, 0,-117,-213, 43, -70, 48, 8, -64,-221, -85, -22, 18, 18, -36,-216, 23; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 13 in 13 different sequences |
| Number of true positive hits | 13 in 13 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Archaea, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | HD Cas3-type |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
13 sequences
CAS3_ECOLI (P38036), CAS3_HALVD (D4GQN8), CAS3_METJA (Q57821), CAS3_METTH (O27158), CAS3_MYXXD (Q1CW46), CAS3_PECAS (Q6D0W9), CAS3_PSEAB (Q02ML8), CAS3_STRTR (F2XG53), CAS3_THET8 (Q53VY2), CS3HD_METJA (Q57829), CS3HD_PYRFU (Q8U336), CS3HD_SACS2 (Q97WW0), CS3HD_THETK (G4RJZ4)» more
|
| PDB [Detailed view] |
9 PDB
3S4L; 3SK9; 3SKD; 5B7I; 5GQH; 7R2K; 7TR8; 7TRA; 8FLJ |