PROSITE logo

PROSITE entry PS51635


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
PURL: https://purl.expasy.org/prosite/signature/PS51635

Direct ScanProsite submission
General information about the entry

Entry name [info] PNPLA
Accession [info] PS51635
Entry type [info] MATRIX
Date [info] 01-SEP-2016 CREATED;
01-SEP-2016 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51635
Associated ProRule [info] PRU01161

Name and characterization of the entry

Description [info] Patatin-like phospholipase (PNPLA) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=181;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=176;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2211545; R2=0.0079003; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1048; N_SCORE=10.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=542; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-23; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 170 in 170 different sequences
Number of true positive hits 170 in 170 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] PNPLA
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
170 sequences

463L_IIV6   (Q91F63), CAPE_ECOLX  (Q6XGD4), CAPV_ECOTW  (P0DTE9), 
» more

PDB
[Detailed view]
5 PDB

1OXW; 4PK9; 4PKA; 4PKB; 6AUN