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PROSITE entry PS51568


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PURL: https://purl.expasy.org/prosite/signature/PS51568

Direct ScanProsite submission
General information about the entry

Entry name [info] SAM_MT43_SET2_1
Accession [info] PS51568
Entry type [info] MATRIX
Date [info] 01-NOV-2011 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51565
Associated ProRule [info] PRU00901

Name and characterization of the entry

Description [info] Histone-lysine N-methyltransferase (EC 2.1.1.43) family profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=762;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=757;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=15.1252804; R2=0.0142351; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=-312619.1562500; R2=121.7487335; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=8070; H_SCORE=669893; N_SCORE=130.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=-605; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-9; D=-20; I=-20; B0=-1000; B1=-1000; E0=-1000; E1=-1000; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 18 in 18 different sequences
Number of true positive hits 18 in 18 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] B_Cuche
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
18 sequences

SET2_ASPFU  (Q4WTT2), SET2_ASPOR  (Q2UTN6), SET2_CANAL  (Q59XV0), 
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PDB
[Detailed view]
2 PDB

2C5Z; 7EA5