PROSITE entry PS51565
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General information about the entry
| Entry name [info] | SAM_MT85_SETD3 |
| Accession [info] | PS51565 |
| Entry type [info] | MATRIX |
| Date [info] |
01-NOV-2011 CREATED;
11-DEC-2019 DATA UPDATE; 27-MAR-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51565 |
| Associated ProRule [info] | PRU00898 |
Name and characterization of the entry
| Description [info] | SETD3 actin-histidine N-methyltransferase (EC 2.1.1.85) family profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=492; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=487; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.0696025; R2=0.0079397; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=5282; N_SCORE=45.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=433; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-46; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='Q'; M= -8,-116, -52, 10,-117, -23, 5,-109, 19, -48,-103, -27, 30, 52, -52, 19, -17, -25,-119,-107; /M: SY='K'; M= -9, 2, -2, -23, -26,-108, -31, -25, 35, -30, -8, -96,-109, 15, -1, 18, -23, 19,-118,-101; /M: SY='R'; M= -10, -21, -39, 6,-108,-112, -15, -42, 7, -30, -97, -98, -16, 48, 61, -98,-100, -8,-113, 1; /M: SY='K'; M= 1,-112, 10, 5,-112, -16, -96, -44, 40, -23, -14, 34,-106, 6, 8, -4, -36, -64,-118,-105; /M: SY='E'; M= -16,-115, -14, 70,-115, -54, -19,-110, 12, -43, 6, -92,-100, 48, 14, -92, -11, -66,-116,-104; /M: SY='L'; M= -54,-108,-111, -47, -45,-118, 14, 24,-104, 54, -77, -41,-114,-103, -3, -48, 13, 14,-112, -15; /M: SY='N'; M= -7,-109, 0, -3, -41, -68, -15, -62, -13, 17, -14, 37,-108, -7, 14, 7, 9, -34,-116, -32; /M: SY='S'; M= -28,-112, 3, 21,-113, 2, -98, -63, 26, -62,-102, -23, -22, 19, 16, 30, -23, -1,-117,-105; /M: SY='L'; M= -32, -8,-113, -48, -86,-118, -26, 32, -14, 61, 20, -35,-115,-101, -5,-106, -97, -16,-110, -44; /M: SY='C'; M= 10, 68,-111,-107, -95,-110, -14, 37, -41, -13, -12,-102,-110,-105,-108, -10, 18, 48,-119, -99; /M: SY='D'; M= -4,-111, 61, 44,-117, -67, -90,-115, 16,-113,-107, 26,-100, 24, -14, 11, -12,-109,-121,-105; /M: SY='E'; M= -12,-110, 24, 53,-109,-102, -13, -63, 32, -59,-101, 18, -99, 25, -37, -7, 20,-104,-114, -6; /M: SY='L'; M=-101, -12,-118,-111, -80,-120,-105, 3,-112, 80, -10, -35,-118, -31,-110,-110, -97, 2,-109, -91; /M: SY='L'; M= -19,-108,-114, -16, 26,-117, -19, -4,-107, 67, -1,-113,-116,-103, -47,-107,-100, -81, 48, 19; /M: SY='Q'; M= -52,-115, 5, 55,-116, -34, -1,-112, 31,-109, -17, -50, -32, 60, 32, -47, -15, -60,-114,-102; /M: SY='R'; M= -65,-112, -40, -9, -20,-113, -35, 20, 27, 22, 8, -47,-109, 0, 41, -54, -37, -20, 10, 18; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='C'; M= -27, 109,-105,-106,-102, -26,-108, -93,-104, -16, -95, -27,-111,-105,-109, 30, 41, 18,-125,-106; /M: SY='T'; M= 7,-104, -98, 5, 14, -24, -25, -92, -96, 15, -10, -93,-104, -2, -40, 41, 46, -27,-111, -94; /I: I=-25; MI=0; MD=-63; IM=0; DM=-63; /M: SY='S'; M= 12,-106, -95, -23,-105, -55, 17, -9, 25, -28, -6, 8,-104, 5, -6, 41, 18, -37,-115, -44; D=-25; /I: I=-25; MI=0; MD=-63; IM=0; DM=-63; /M: SY='P'; M=-101,-119, 23, -18,-121,-108, -10,-113, 11, -67, -34, -40, 54, 48, -96, 14, 24, -69,-124,-110; D=-25; /I: I=-25; DM=-63; /M: SY='P'; M= -8,-111, -41, -33, -54, -15, -10, -46, -27, -25, -24, -6, 51, 10,-101, 33, 24, -30,-116, -22; D=-25; /I: I=-25; DM=-63; /M: SY='P'; M= -11, -11, -34, 6,-109, -14,-101, -16, -93, -40, -98, -18, 80, -94, -5, 25, 2, -19,-116,-107; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='N'; M= -67,-105, -7, -42,-109, -19, -9,-108, -15,-111,-103, 68, -16, 18, -93, 50, 44,-104, 12, -47; /M: SY='P'; M= -6,-112, -14, -33,-111, -18, -31,-101, -40,-108,-101, -35, 85, 7, -60, 33, -2, 1,-115, -36; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='N'; M= 19,-106, 4, -8,-112, 14, -94,-101, -8,-106,-100, 49, -59, 45, -93, 28, -35, 8,-117,-104; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='E'; M= -29,-110, 25, 52, -44,-101, -91, -8, 32, -64,-100, 42,-100, 22, -35, 1, -2,-101,-115, -44; /M: SY='E'; M= -6,-107, 6, 44, -33, -51, -13, -60, -38, 34, -10, -32,-104, 3, -19, -4, 1, -11,-113, -96; /M: SY='W'; M= -54, -19,-121, -44, -3,-113,-113, 12,-104, 28, 41,-117,-113, -6, -29,-110,-106, -46, 140, -75; /M: SY='E'; M= 3,-109, 31, 65,-115, -71, -90,-112, 4,-111,-105, 43, -31, 2, -46, -9, 21,-106,-119,-106; /M: SY='E'; M= -51,-111, 28, 60,-101,-104, 22, -23, -43, -17, -95, 22,-101, 31, -92, 5, -26, -31,-110, 27; /M: SY='H'; M= -51,-111,-104,-101, 69,-112, 98, -43, -99, -14, -35, -96,-113, -1, -16,-100,-100, -17, -92, 58; /M: SY='K'; M= -51,-109, -39, 0, -98, -63, -96, -19, 43, 23, 7, 2, -62, 5, 37, -60, -37, 16,-112, -97; /M: SY='E'; M= -17,-112, -26, 66, -35, -58, 12, -67, 27, -66, -20, -16, -99, 56, -15, -30, -94, -8,-113, -99; /M: SY='I'; M= -30,-107,-117,-113, -30,-118,-110, 77,-110, 43, 23,-110,-111,-106,-112, -28, -58, 6,-108, -90; /M: SY='H'; M= -32, -16, 3, -19, -19, -28, 47, -96, -44, -21, -92, 6,-107, 25, 41, 8, -54, 8, -11, 39; /M: SY='N'; M= -1,-106, 15, 35,-110, 5, -92, -44, 10, -63,-101, 44,-100, -15, -17, 31, 8, -35,-117,-103; /M: SY='I'; M= -9, 13,-108, -21, -46, -62,-105, 48, 5, 44, -8,-104,-109, -37, -41, -55, -18, 16,-109, -93; /M: SY='L'; M= -36,-104,-114,-107, -26,-116,-108, 36, -66, 57, -71,-109, -36, -19,-107, -48, -3, 43,-109, -91; /M: SY='E'; M= -32,-110, 49, 50,-112, -48, 7,-106, 11, -53, -15, 10, -38, 44, -25, -11, 8, -43,-117,-100; /M: SY='E'; M= -14,-111, -14, 57,-114, -46, -89,-113, 54,-110,-101, 0, -98, 32, 44, -31, -19,-107,-112,-102; /M: SY='I'; M= -98,-108,-118,-114, -19,-122, -17, 83,-112, 41, -69,-111,-111,-108,-113,-107, -39, 21,-108, -88; /M: SY='R'; M= 6, -14, -37, 4, -47,-100, -91, -19, 17,-102, 2, 17,-103, 13, 68, 23, -20, -64,-112, -98; /M: SY='K'; M= -20,-110, 3, 40, -44, -40, -91, -2, 50, -62, -36, 8, -38, 18, 19, -3, -28, -71,-110, -27; /M: SY='L'; M= -53, -15,-111, -43, -3, -61,-105, 48, 6, 54, -1,-106,-111,-100, -10,-102, -16, 0,-106, -89; /M: SY='Q'; M= -94,-116, -31, 79,-116,-105, -85,-110, -76, -60, -97, -87, -96, 99, -40, -44, -38, -70,-110, -34; /M: SY='K'; M= 10,-107, 5, 11, -11, -51, -92, -49, 51,-106, -99, 9, -18, 19, 11, 25, -3, -55,-111, -98; /M: SY='N'; M= -29,-109, 10, 27,-111, 16, -41, -50, 11, -59, -38, 37, 33, 11, -16, 18, -20, -27,-115,-104; /M: SY='L'; M= -16,-106, -35, -48, 25,-108, -5, 24, 9, 42, -79, 19,-110, -28, -41, -17, -92, -14, -11, 15; /I: I=-17; MD=-42; /M: SY='S'; M= -29, 33, 32, -57,-108, -11, -99, -43, 1, -59, -36, -12, 8, -13, -23, 42, 9, -4,-119, -27; D=-17; /I: I=-17; MD=-42; /M: SY='D'; M= -37,-127, 21, -28,-121, -32, 15,-118, -5, -24, 2, -53, -39, -8, -2, -25, 1, -73,-132, -30; D=-17; /I: I=-17; MI=0; MD=-42; IM=0; DM=-42; /M: SY='D'; M= -33,-136, 8, -3, -43, -36,-123, -32, -33, -42,-121, -10, 5,-117, -50, -24,-117, -29,-139, -53; D=-17; /I: I=-17; DM=-42; /M: SY='S'; M= -38, -10, -42,-101,-106,-109, 13, -20, -2, -11, -29, 17, -19, -12, 1, 23, 13, 16, 3,-103; D=-17; /I: I=-17; DM=-42; /M: SY='P'; M= -7, -15, -60, -5, -29, -28, 10, 11, -5, -10, 1, -37, 30, -27, -24, -21, 12, 26,-115, -98; D=-17; /I: I=-17; DM=-42; /M: SY='P'; M= 1,-110, -1, 7, -56, -52, 3, -52, 25, 4, -92, 19, 34, 17, -38, -27, -20, -10,-111, -6; D=-17; /I: I=-17; DM=-42; /M: SY='Q'; M= -57,-109, -9, -19,-106, -8, -92,-101, 20, -9, -95, 3, 27, 51, 12, 40, -7, -39,-111, -33; /M: SY='R'; M= -5,-110, -37, 23, -55, -15, -22, -5, -19, -46, -94, -12, 16, 25, 33, 7, 1, -19, -15, 21; /M: SY='D'; M= -18, -34, 50, -45,-113, -63, -1,-109, 16,-111,-102, 29, 47, 7, 20, 5, 31,-106,-119,-103; /M: SY='R'; M= -56,-110, 1, -87,-105,-105, -15,-104, -28, -11, -94, -25, -30, -25, 91, 5, 23, -50,-113, -97; /M: SY='E'; M= 8,-108, 16, 46,-106, -48, -10, -63, 14, -5, -18, -14, -10, 35, -42, 22, -51, -46, 9, -99; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='A'; M= 44,-105, 20, 25, -36, -19, -94,-100, 1, -44, -22, -4, -34, 35, -6, -26, 2, -23,-112,-100; /M: SY='N'; M= -5, -33, 20, -12, -42, -51, 29, -68, -8, -55, -97, 43,-102, 31, 34, 22, 17, -66,-114, -18; /M: SY='L'; M= -99,-106,-117,-111, 42,-118,-106, 42, -53, 52, 11,-111,-114, -57, -40, -54, -95, 25, 30, -27; /M: SY='E'; M= 0,-110, 24, 55,-114, 5, -22, -58, 1, -67,-102, 2, 36, 18, -42, 3, -16,-105,-115,-104; /M: SY='N'; M= 29,-107, 6, 41,-112, -62, -92, -44, 24,-106, -99, 44, 1, 21, -24, -8, -16, -27,-115,-103; /M: SY='F'; M=-107,-105,-121,-116, 113,-117,-102, -29,-112, 20, -80,-111,-119,-118,-110, -54,-100, -84, -79, -28; /M: SY='M'; M= -95, -34, -99, 23, -9,-112, -37, 5, 3, 34, 48, -35,-106, -6, -4, -54, 12, 20,-108, -35; /M: SY='Q'; M= 7,-108, -26, 39,-109, -64, -91, -47, 39, -41, -32, 7, -99, 47, 21, -7, 6, -29,-112,-100; /M: SY='W'; M=-108,-131,-130,-110, 1,-107, -15,-106, -9,-103,-105,-122,-112,-103,-104,-113,-118,-119, 174, -62; /M: SY='C'; M= 35, 65, -48,-105, 3,-106,-102, -35,-106, 63, -9,-106,-112,-103,-107, -49, -35, -41,-106, -25; /M: SY='K'; M= -28,-107, 8, 20, -60, -54, 28, -46, 66, -44, -96, 32, -99, 5, -35, -25, 18, -29,-113, -97; /M: SY='E'; M= -10,-109, 39, 54,-112, -30, -15,-110, 18, -49, -27, 3, -98, 32, 20, 22, -55,-105,-115,-101; /I: I=-38; MD=-97; /M: SY='N'; M= -15, 15, -84, -42,-108, -58, 57,-102, -7,-104, 35, 92,-107, -5, -18, -37, -88, -12,-124, -99; D=-38; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='G'; M= -86, -15, -54, -31, -46, 89,-103,-118, -4,-116,-108, -4,-103, -97,-103, -18, -41, -52,-111,-109; D=-38; /I: I=-38; DM=-97; /M: SY='I'; M= 42, 36,-109,-106, -29, -2, -17, 47,-104, -27, 9,-101,-107,-103,-107, -91, -13, 43,-110, -26; /M: SY='Q'; M= -32, -10, 26, 13, 0, -49, 7, -20, 37,-102, -96, 3,-100, 54, -22, 9, 24, -64,-110, -40; /M: SY='F'; M= -29,-105, -13, -37, 43,-105, 31, -11, -93, 7, 25, -17,-107, -5, 15, 19, 5, 15,-103, -3; /I: I=-26; MI=0; MD=-67; IM=0; DM=-67; /M: SY='D'; M= -30, 24, 64, 43,-112, -12, 20,-114, -39,-112,-105, 44,-100, -1, -35, 26, -58,-109,-120, -41; /M: SY='G'; M= -2,-107, -53, -46,-113, 65, -22,-111, 41,-112,-103, 30, 1, -27, -27, 7, -91, -44,-111,-105; /I: I=-33; MI=0; MD=-84; IM=0; DM=-84; /M: SY='V'; M= -92, 33,-116,-112, 11,-118,-111, 44,-109, 3, -75,-111, -37,-110,-110,-102, -89, 77,-107, 15; /M: SY='E'; M= -33, -21, 18, 47, -60, -38, -91,-106, 35,-107,-101, -10, -97, 16, -6, 32, 41, -52,-115,-101; /M: SY='I'; M= -18,-106,-118,-114, 41,-118,-113, 83,-110, -1, -8,-110,-110,-109,-112,-103, -61, 35,-103, -83; /M: SY='K'; M= 31,-106, 14, 15,-107, -18, 18, -13, 36, -99, -15, -87,-100, 10, 17, -4, -14, 2,-113, -98; /M: SY='E'; M= -20, -15, 10, 56, -57, -51, 52, -59, 22,-105, -98, 0, -98, 33, -31, 14, -35,-105, 3, 22; /M: SY='F'; M= -97, 7, -3,-104, 85, -24, -18, -2,-103, -46, 26, 10,-110,-105,-105, -8, 9, 10, -93, -7; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='D'; M= -94,-111, 50, 43,-109, 24, -42,-106, -19, -1, -99, 20, 43, -36, -95, -27, 5,-105,-117,-104; D=-36; /I: I=-36; DM=-90; /M: SY='D'; M= -5,-109, 53, 9,-111, 47, -40,-107, -21, -29,-101, 27, -3, 15, -36, -28, -43, -36,-116,-104; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='Y'; M= -52, 12, -25, 49, -22, -24, -14, -53, -45, -51, 35, -32,-103, 35, -21, -7, -40, -50, -91, 79; /M: SY='G'; M= -58,-110, -5, 9,-114, 94, -99,-121, -98,-117,-108, -5,-101, -38,-105, -84, -99,-116,-108, -23; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='Y'; M= -53, 9,-105,-104, 62,-108, -90, -15, -44, 37, -12, 27, -37, -19,-100, -22, -93, -43, 6, 68; /M: SY='G'; M= -43, -33, -96, -54,-115, 100,-102,-121, -49,-117,-107, -83,-101, -24,-106, -20, -98,-114,-107,-109; /M: SY='L'; M= -44,-102,-116,-109, -77,-117,-105, 9,-108, 78, -22,-113,-114,-104, -42,-106, -92, 40,-107, -88; /M: SY='K'; M= -94, -14, -94, 27, 16,-110, -97, 26, 45, -48, -87, -93,-103, 15, 39, -42, -18, 34,-106, -91; /M: SY='A'; M= 94, -15, -98, -92,-106, -83,-100, -96, -94, -57, -93, -92, -98, -91, -99, 21, -7, -58,-109,-102; /M: SY='T'; M= -34, 3, 7, 11,-102, -99, -94, -48, 24, -43, -11, 4, -97, -85, 9, 15, 74, -3,-116, -98; /M: SY='Q'; M= -35, 20, -44, 45, -42, -10, -90,-101, 44, -63, -20, -87, -99, 53, 47, -43, -25, -4,-108, -97; /I: I=-26; MI=0; MD=-67; IM=0; DM=-67; /M: SY='D'; M= -18,-109, 95, -14, -52, -94, -31,-109, -87, -78,-105, 25, 23, -3, -94, 10, -18,-107,-117, 10; /M: SY='I'; M= -33,-106,-115,-112, 32,-117, -12, 84,-109, 30, -69,-108,-109,-106,-110,-103, -46, 11,-100, -20; /M: SY='K'; M= 43,-105, -42, 20,-110, -94, -14,-103, 60, -66, -95, -3, 25, 43, -36, -10, -46, -50,-109,-100; /M: SY='E'; M= 27,-108, -32, 76,-108,-100, -89, -32, 47,-102, -37, -35, -37, 23, -36, -32, -89, -40,-108, -32; /M: SY='G'; M= -51,-107, 38, -6,-114, 78, -92,-117, -35,-115,-106, 44, -99, 0, -97, 12, -91,-112,-112,-106; /M: SY='E'; M= -50, -29, 40, 79,-113, -99, -17,-108, -79,-106,-101, -36, -93, 55, -86, 29, 17, -53,-115,-100; /M: SY='L'; M= -94, 32, -25, 12, -90,-109, -96, -19, 4, 51, -13, -15, 14, -2, 15, -48, -18, 12,-110, -94; /M: SY='F'; M= -95, -27,-115, -46, 58,-117,-107, 45,-108, 42, -4,-110,-112,-107,-108,-104, -91, 52, -13, -78; /M: SY='L'; M= -30, 7,-116,-110, 22,-115,-106, 50,-108, 57, 36,-110,-112,-105,-108,-104, -91, 33,-103, -84; /M: SY='T'; M= 13, -36, -88, 10, -36, -61, -14, -99, 10, -74, -95, 3, -98, 2, 34, 39, 54, -31, -13, -25; /M: SY='V'; M= -49,-103,-116,-112, -84,-118,-117, 77,-108, -47, -71,-109,-109,-108,-111,-101, -86, 82,-113, -91; /M: SY='P'; M= -63,-123, -98, -40,-118,-100,-101,-106, -94,-116,-102,-104, 128, -97,-107, -43, -90,-110,-111,-115; /M: SY='R'; M= -17, -12, -26, 33,-103, -49, -88,-102, -1, -40, 5, -32,-103, -38, 91, -43, -54, -18,-108, -23; /M: SY='K'; M= -1,-105, -45, 0,-109, -27, 29,-109, 72, -72, -98, 39, -33, -77, 17, 31, -39,-104,-111, -97; /M: SY='L'; M= 37, 2, -14, -99, -84,-105, -12, -8, -46, 64, -18,-103,-108, -26,-102, -94, -37, 18,-108, -91; /M: SY='M'; M= -52,-103,-116,-109, 18,-112, -96, 55,-104, 15, 120,-106,-106, -98,-103,-104, -92, -19,-102, -81; /M: SY='M'; M= -99,-102,-117,-110, 63,-114, -97, 16,-106, 57, 98,-109,-111,-102,-104,-106, -95, -73, -95, -74; /M: SY='T'; M= -81, 14, -10, -90, -38, -47, -95, -99, -53,-101, -97, -78, -95, -25, -95, 75, 84, -91,-114, -29; /M: SY='W'; M= -14, -17, -55, 19, -25,-102, -12, 4, -44, 3, -85, -33,-101, -23, -97, 26, 50, 32, 50, -39; /M: SY='D'; M= -49,-107, 63, 62,-106,-100, 12,-100, -27, -34, -9, -26, -96, 7, -38, 16, 20, -16,-117, -46; /M: SY='T'; M= -9, -99, -6, -37, -58, -92, 24, -97, 7, -19, -93, 51, -97, -22, -90, 48, 65, -51,-116, -96; /M: SY='A'; M= 82, -97, -57, -20, -98, -49,-101, 3, -96, 4, 3, -43,-101, -92,-100, -22, -86, -2,-108, -98; /I: I=-17; MD=-44; /M: SY='K'; M= -29, 10, -99, -28,-104, -51, 12, -22, 40, -23, 4, -49, -19, 34, 38, 6, -56, -35,-111, 3; D=-17; /I: I=-17; MI=0; MD=-44; IM=0; DM=-44; /M: SY='S'; M= -40, -11, -27, 14,-111, -46, -96, -52, 33, -35, -17, 24, -32, -51, 13, 46, 6, -65,-119,-105; D=-17; /I: I=-17; DM=-44; /M: SY='S'; M= 0,-104, -17, -32,-105, -53, -95, -63, -19, -59, -98, -28, 46, -20, -9, 67, 29, -17,-113, -30; D=-17; /I: I=-17; DM=-44; /M: SY='P'; M= -7, -42, 8, 5, -20, -13, -96, 9, -14, -42, 29, -51, 46, -52, -16, 13, -28, -4, 13, 19; D=-17; /I: I=-17; DM=-44; /M: SY='L'; M= -16, -7, -60, -64, -9, -49,-100, 3, -49, 67, 11,-107, -40,-100, -11, -46, -38, -16,-103, 4; D=-17; /I: I=-17; DM=-44; /M: SY='G'; M= 5,-109, -94, 3, -36, 48, -96, -65, 40, -11, -96, -13, 5, -44, 7, -6, -93,-102, 32, -19; D=-17; /I: I=-17; DM=-44; /M: SY='K'; M= 11, -24, 33, -21, -62, -35, -32, -99, 49, -39, -35, -29, 34, 25, -42, 0, 2, -24,-107, 11; /M: SY='L'; M= -15, 26, -51, -47, 16,-110, 8, 29, -37, 57, -1, -54, -12, -26, -39, -46, -37, -14,-103, -28; /M: SY='I'; M= -25, -4, -33,-107, 50,-113, -32, 57, -47, 38, -16,-104,-110,-104,-105, -63, -10, 15, -98, -11; /M: SY='E'; M= 2,-107, 1, 53,-103,-100, -88, -63, 47, -3, -18, -2, -98, 11, 32, 5, -89, -65,-108, -37; /M: SY='N'; M= 4,-105, 13, 5,-105, -45, -9, -98, 33, -10, -35, 37, -20, 27, 32, 16, -52, -16,-112, -97; /M: SY='D'; M= -96, -21, 105, 2, -50, -30, -17,-111, -87, -62,-108, 27, -7, -86, -95, -18, -88, -50,-127,-101; /M: SY='P'; M= -54,-113, -17, -25,-108, -31, -22, -8, 18,-103, 14, 12, 97, -89, 10, -59, -15, -28,-112,-104; /M: SY='M'; M= -32, -11,-115,-108, -35, -62,-102, 58, -57, 58, 76,-108,-109, -39,-105,-103, -92, -14,-105, -86; /M: SY='L'; M= -28, 51,-115,-108, -1,-114,-103, -9, -47, 72, 33,-110,-114,-103,-105,-103, -92, 23,-105, -86; /M: SY='Q'; M= -4,-107, -43, -79,-111, -16, -88,-109, 47,-107, -97, -82, -99, 68, 59, 48, -46,-104,-108, -97; /M: SY='S'; M= -20,-104, -35, 5,-105, 1, 32, -98, 5, -22, -93, 34, -99, 42, 2, 50, -11, -6,-113, -96; /M: SY='M'; M= -58,-101, -42,-102, 16,-106, -88, -34, -98, -18, 138,-100, -24, -30, -97, -25, -90, -19,-103, -80; /M: SY='P'; M= -9,-113, 33, 26,-115, 11, -33,-108, -90,-112,-103, -90, 101, -89,-100, 10, -47,-107,-113,-108; /M: SY='N'; M= -90, -99, -29, -87,-107, -84, 5,-106, -81,-111,-100, 117,-102, -3, -88, 22, 14,-106,-124,-100; /M: SY='V'; M= -27, -9,-114,-108, -32,-114,-112, 26,-106, 24, -71,-109,-110,-106,-107, -98, -37, 88,-113, -90; /M: SY='A'; M= 55, 44,-101, -95, -97, -6, -98, -13, -52, 6, 35, -42, -10, -9, 9, 1, -17, -1,-109, -97; /M: SY='L'; M= -98,-100,-114, -46, -72,-117, -99, -64,-108, 94, -19,-114,-115,-101,-106,-108, -94, -51,-103, -85; /M: SY='A'; M= 89, -18, -98, -92,-104, -83, -99, -92, -92, -97, -92, -91, -99, -89, -16, 37, -49, 3,-109,-101; /M: SY='L'; M= -98,-102,-114, -46, 35,-117,-100, 40,-108, 76, 19,-111,-112,-103,-106,-106, -94, -41, -97, -9; /M: SY='H'; M= -4, 8, -19, -95, 62, -49, 102, -48, -92, -18, 41, -89,-106, -91, 11, -42, -37, -56, -99, 17; /M: SY='L'; M= -95,-100,-115,-108, -75,-116,-102, -13,-108, 84, 17,-112,-113,-102,-106,-105, -40, 32,-105, -86; /M: SY='L'; M= -22, 74,-114,-108, -78,-113, -31, 21,-107, 75, 28,-109,-113,-103,-107,-103, -92, -20,-107, -89; /M: SY='C'; M= -18, 73, -29, -43, -7, -21, 50, 9, -39, 15, 0, 12,-108, -29, -98, -45, -42, 23,-104, 36; /M: SY='E'; M= -91,-112, -65, 110,-113,-107, -10, -47, -74, -57,-100, -88, -88, 36, -82, -88, -92,-105,-111,-102; /I: I=-33; MI=0; MD=-84; IM=0; DM=-84; /M: SY='R'; M= -13, 24, -94, -86, -33,-100, -12, -55, 52, -7, -89, -47, -5, 2, 55, 26, -38, -62, -99, 39; /M: SY='L'; M= -27, 23,-101, -97, 23,-106, 7, -40, 13, 54, -75, 15,-109, -5, -6, -27, -33, -20, -96, 40; /M: SY='N'; M= -50,-104, 16, -1,-108, 34, -20,-107, 38, -46, -99, 60, -98, -15, 5, 36, -31, -60,-113,-100; /M: SY='P'; M= -30,-112, 24, 47,-109, -6, 11,-104, 6, -19, -97, -89, 87, -30, -92, -3, -60, -72,-112,-103; /M: SY='D'; M= -26,-106, 72, 3, -16, -93, -85,-105, 39, -81, -17, 62, -5, -48, -20, 12, -84, -51,-116, -97; /M: SY='S'; M= -73, -95, -86, -88,-106, -80, -90,-105, -88,-109,-102, -27, -95, -80, -92, 113, -67, -98,-114, -97; /M: SY='F'; M= -98,-104, -99, -30, 95,-105, -27, -88, 33, -42, 11, 16, 18, -96, -50, -17, -5, -62, -86, -1; /M: SY='W'; M=-106,-127, -44,-109, 16,-106, -15, -41,-103, -56, -99,-120,-111,-103,-106,-111,-114,-110, 174, -2; /M: SY='K'; M= 33, -10, -90, -52,-104, -34, 47, -49, 66, -35, -37, -28, -98, 33, 26, -4, -25, -97,-107, -51; /M: SY='P'; M= 9,-114, 0, -41,-114, -25, -32,-104, -43,-111,-100, -95, 114, -93,-102, 7, -87, -51,-111,-109; /M: SY='Y'; M=-102,-113,-101,-104, -50,-108, -68, -88, -97, -85, -81,-103,-114, -92, -94, -45, -96, -93, -59, 139; /M: SY='I'; M= -97,-105,-117,-113, 29,-119,-108, 89,-110, 47, 8,-109,-109,-106,-110,-106, -92, -34,-100, -81; /M: SY='D'; M= -8,-105, 77, -15,-106, -63, 6,-108, 7, -68,-101, 66, -99, -42, -3, 22, -49,-105,-116, 0; /M: SY='I'; M= -37, -2,-106,-103, -40,-106,-105, 62, -45, 1, 32, -97,-103, -98,-103, 32, 26, 46,-110, -90; /M: SY='L'; M= -99,-100,-116,-108, -14,-117,-100, -41,-109, 94, -60,-115,-115,-102,-106,-109, -95, -71,-101, -83; /M: SY='P'; M= -98,-123, -98, -87,-117, -99,-101,-105, -94,-116,-102,-105, 131, -98,-107, -95, -90,-110,-111,-115; /I: I=-21; MD=-53; /M: SY='S'; M= -21,-104, 8, 27,-108, -5, 2, -52, 32,-105, -98, -8, -96, 9, 16, 48, 29, -38,-113, -98; D=-21; /I: I=-21; MI=0; MD=-53; IM=0; DM=-53; /M: SY='S'; M= -51, -13, -3, -3,-103, -46, -92, -9, 15, -98, -94, 9, -97, -27, 22, 58, 53, -2,-114, -97; /M: SY='Y'; M= -52,-108,-104, -46, 83,-108, -78, -86, -99, -80, -15, -6,-114, -99, -98, -98, -96, -90, -66, 114; /M: SY='T'; M= -3,-100, 18, -22, -33, -29, 37,-100, -86, -79, -96, 51, 6, -86, -19, 44, 54, -49,-112, 2; /M: SY='T'; M= -86, -95, -94, -96, -91,-103, -99, -40, -93, 23, 10, -53, -96, -95, -99, -24, 105, -10,-115, -93; /M: SY='P'; M= -94, 28,-104, -94, -16,-105,-105, -1, -99, -56, -89,-105, 109,-102,-107, -96, -36, 45,-111,-102; /M: SY='L'; M= -53,-100,-114,-107, -7, -49, -37, -36,-107, 82, 51,-111,-113,-101,-105,-105, -93, 11,-103, -83; /M: SY='Y'; M= -52, -38, -38, -22, 53, -49, -15, -89, -96, -52, -16, -33,-110, -29, -95, -5, -94, -93, -69, 117; /M: SY='F'; M=-102,-106,-113,-110, 102, -55, -89, -82,-104, -30, 39,-105,-114,-106,-102, -24, -97, -87, 50, 80; /M: SY='T'; M= -81, -97, 2, -18,-104, -42, -91,-100, -17,-104, -98, 33, -94, -84, -41, 72, 78, -94,-117, -98; /M: SY='P'; M= -2,-106, -20, 19, -54, -51,-100, 30, -25, 20, -12, -98, 68, -26, -99, -43, -1, 13,-109, -96; /M: SY='E'; M= 16,-107, 61, 72,-111, -64, -28,-107, -18, -39,-100, -8, -37, 15, -40, -10, -8,-102,-115,-100; /M: SY='D'; M= -94,-111, 83, 81,-114,-101, 23,-112, -79,-108,-104, -77, -93, 29, -87, -86, -13, -51,-120,-100; /M: SY='M'; M= -98,-102,-116,-108, 47,-114, -96, 12,-106, 66, 90,-109,-111,-101,-104,-106, -94, -31, -95, -3; /M: SY='E'; M= 22, 11, -32, 60,-103,-100, -88, -63, 21, 2, 23, -19, -97, 58, 5, -85, -17, -94,-108, -97; /M: SY='E'; M= 29,-104, -9, 53, -19, -55, 15, -44, -38, 31, 4, -92,-100, 1, -37, 1, -89, -89,-100, 37; /M: SY='L'; M= -98,-101,-115,-107, -44,-117, -99, 0, -50, 90, -22,-113,-114,-101,-105,-108, -94, -42,-101, -24; /M: SY='K'; M= -30,-107, -31, 10, -43, -99, -87,-105, 79,-103, 10, -52, -97, 44, 46, 10, -38, -53,-106, -95; /M: SY='G'; M= -58,-108, -39, -43,-111, 83, 25,-111, -96,-112,-102, 13, 50, -93,-103, 12, -92, -37,-110,-104; /M: SY='S'; M= -77, -17, -89, -90, -11, -87, -92, -98, -89, -68, -18, -78, -95, -23, -94, 96, 60, -92,-112, -94; /M: SY='P'; M= -23, -12, -40, -87,-106, -52, -23, -98, -24, -45, -14, -42, 102, 11, -97, 26, 5, -31,-109, -22; /M: SY='A'; M= 55, 12,-102, -98, -93, -97,-103, 17, -98, -6, 6, -49,-101, -96,-102, -8, 47, 42,-112, -96; /M: SY='F'; M= -1,-102,-112, -48, 84,-110, -95, -12, -71, 50, 19,-107,-112,-104,-103,-101, -94, -40, -84, 42; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='E'; M= -1,-106, 19, 78,-105, -16, -33, -98, -81, -64, -16, -86, -34, 17, -29, 15, -4, 7,-111, -22; /M: SY='E'; M= -31,-107, 48, 70,-106,-100, -90, -98, -22, -17, 4, -85, 34, -79, -16, 20, -3, -16,-114,-100; /M: SY='A'; M= 78, 5,-102, -96, -38, -89,-102, 15, -97, -87, 5, -94,-100, -94,-101, 18, -10, 29,-109, -97; /M: SY='L'; M= -95,-102, -42,-107, 0,-116, -14, 50,-107, 65, 13,-108,-111,-103,-106,-104, -53, 30,-101, 4; /M: SY='K'; M= -92,-105, -86, -30, -8, -98, 9, -44, 69, -5, -90, 52,-100, 19, 31, 15, -37, -50,-107, -91; /M: SY='Q'; M= -16,-106, -38, -37, 18,-102, 33, -58, -86, 33, 4, 7,-103, 94, -86, -87, 1, -51,-102, -17; /M: SY='Y'; M= -97, 68,-107,-107, 44,-111, -7, 27,-102, 9, -13, -49, -38,-101,-103, -50, -11, 6, -84, 86; /M: SY='R'; M= -42,-111, -94, -82, -38,-106, -85, -34, 54, -38, -91, -88,-104, -1, 96, -92, -94,-100, -99, 27; /M: SY='N'; M= -33, -99, -39, -89, -9, -25, 33,-102, -84,-106, -97, 98,-101, -83, -25, 52, 6, -34,-118, -95; /M: SY='I'; M= -30,-105,-110,-108, -7, -54, -11, 89,-104, -45, -1,-101,-105, -32,-107, -6, -22, 33,-105, -23; /I: I=-8; MD=-21; /M: SY='A'; M= 69, 66,-103, -99, -96, -52,-103, 3, -99, -18, 15, -96,-103, -96,-103, 1, 6, 13,-110, -34; D=-8; /I: I=-8; MD=-21; /M: SY='R'; M= -98,-114, -94, -83,-108,-107, -85, -55, 22,-106, -96, -22,-106, -73, 113, -50, -95,-106,-108, -95; D=-8; /I: I=-8; MD=-21; /M: SY='Q'; M= -91,-115, -87, -68,-118, -99, -80, -45, -73, -59, -88, -32, -99, 133, -74, -32, -93,-106,-105, -93; D=-8; /I: I=-8; MD=-21; /M: SY='Y'; M=-104,-112,-105,-107, 46,-111, -72, -87, -99, -83, -82,-105,-116, -96, -96, -99, -98, -93, -61, 132; D=-8; /I: I=-8; MD=-21; /M: SY='A'; M= 71, 40,-102, -98, -97, -4,-103, 8, -98, 7, -86, -95,-102, -95,-103, 10, 0, -7,-110, -99; D=-8; /I: I=-8; MD=-21; /M: SY='Y'; M= -54,-112,-102,-102, 17,-108, 28, -43, -96, -61, -82,-100,-113, 6, -94, -49, -96, -63, -65, 127; D=-8; /I: I=-8; MD=-21; /M: SY='F'; M=-103, 24,-117,-113, 100,-115,-100, 9,-109, 33, -76,-109,-116,-112,-107,-105, -38, -42, 12, 17; D=-8; /I: I=-8; MD=-21; /M: SY='Y'; M=-101, 8,-101, -98, 31,-109, 71, -40, -4, 21, -21, -29,-111, -27, 10, -98, -96, -91, 3, 93; D=-8; /I: I=-8; MD=-21; /M: SY='K'; M= -49,-106, -40, -82,-103, -98, -13, -54, 63, 1, 7, 43,-101, 37, 41, 19, -36, -98,-109, -95; D=-8; /I: I=-8; MI=0; MD=-21; IM=0; DM=-21; /M: SY='L'; M= -51,-112, -41,-108, -12, -38, -1, 22, -34, 46, -84, -12,-116, -9, -42, -14, 3, -37,-116, -97; D=-8; /I: I=-8; DM=-21; /M: SY='F'; M=-104,-111, -17, -49, 68, -74, -10, -26, -7, 25, 5,-104,-115, -6, -29, -25, -6, -16,-101, -32; D=-8; /I: I=-8; DM=-21; /M: SY='Q'; M= -7,-115, -43, 29, 3, -58, 32, -54, -8, -29, -96, -94,-106, 71, 6, 0, -97, -38, -12, -22; D=-8; /I: I=-8; DM=-21; /M: SY='N'; M= -30,-107, 18, -31,-106, -15, 22, -30, -22, -16, 9, 40, -15, -52, 0, 37, 29, -99,-120,-100; D=-8; /I: I=-8; DM=-21; /M: SY='H'; M= -35,-105, -10, -39, 18, -26, 48, -47, 3, -14, 0, 11, 29, -22, -2, 48, -9, -97,-106, 0; D=-8; /I: I=-8; DM=-21; /M: SY='P'; M= -49,-109, 45, -9, -47, -25, -2, -61, 10, -8, -19, -5, 60, -5, -39, 8, -16, -7, 3, -21; D=-8; /I: I=-8; DM=-21; /M: SY='D'; M= -52, 10, 46, 42, 26,-101, 5, -15, -39, -3, -92, 36, -38, 6, -93, 0, -17, -51,-108, -11; D=-8; /I: I=-8; DM=-21; /M: SY='P'; M= 30,-105, -93, -18, -1, -21, 10, -29, 4, -40, -44, 15, 52, -3, -48, 28, 1, -95,-105, 10; D=-8; /I: I=-8; DM=-21; /M: SY='S'; M= 18,-103, -27, -21, -97, -33, -9, -14, 10, -8, 2, -4, 16, -26, -43, 37, 1, 15,-110, -7; D=-8; /I: I=-8; DM=-21; /M: SY='S'; M= -33,-107, -20, -97, -35, 4, -20, 3, 13, 9, -15, -25, 4, -53, -47, 48, 7, -31,-114, -99; D=-8; /I: I=-8; DM=-21; /M: SY='P'; M= -28, -43, -3, -67, -31, -14,-105, 19, 13, 36, -86, -34, 48, -39, -58, -62, -57, -43, 27, -98; D=-8; /I: I=-8; DM=-21; /M: SY='P'; M= -39,-113, -43, -11, 25, -53, -37, 35,-101, 14, -32, 2, 53, -44, -15,-101, -50, -9,-107, -16; D=-8; /I: I=-8; DM=-21; /M: SY='L'; M= -19, -13,-108,-104, 10, -60,-101, -6, -44, 43, 14, -32, 11, -22, -19, -22, 32, -64,-107, 0; D=-8; /I: I=-8; DM=-21; /M: SY='R'; M= -52,-112, -44, -43,-102, -72, -16, -17, 38, -26, 28, 7, -14, -3, 41, 0, -13, -7,-112, 1; D=-8; /I: I=-8; MI=0; MD=-21; IM=0; DM=-21; /M: SY='D'; M= -10,-105, 51, 31, -45, -14, 36, -54, 15,-105, -98, 49, -20, -9, -1, -3, -2, -29,-116, -96; /M: SY='N'; M= -3, 43, -13, -41, -33, -25, -8, -60, 5, -64, -94, 67, -37, -20, 6, 1, 4, -8, 42, 31; /M: SY='F'; M=-106,-103,-119,-114, 123,-114, -99, -50,-110, -21, -80,-108,-117,-119,-107,-105, -98, -84, -73, -18; /M: SY='T'; M= -84, 68, -91, -94, -99, -98, -15, -93, -91, -59, -92, -38, -94, -93, -98, 19, 107, -85,-120, -98; /M: SY='Y'; M=-104,-108,-112,-109, 89,-111, -86, -82,-103, -4, -81,-108, -40,-104,-101,-103, -98, -45, 72, 100; /M: SY='D'; M= 5,-106, 77, 49,-112, -12, -86, -50, 2,-109,-103, 35, -96, -13, -42, 9, -39,-104,-118,-101; /M: SY='D'; M= 9,-103, 53, 36, -25, -99, -89, -87, -89, 45, -83, 42,-102, -28, -57, -58, -16, -49,-109, -19; /M: SY='Y'; M=-104,-111,-106,-107, 69,-110, -75, -86,-100, -81, -82,-105,-115, -98, -97,-100, -98, -92, 41, 125; /M: SY='R'; M= -97, 57, -99, -88, 2,-108, -90, -22, -2, -10, -90, -92,-108, -3, 98, -45, -44, -97, 41, -89; /M: SY='W'; M=-109,-134,-136,-113, -73,-107,-136,-106,-105,-104,-107,-129,-112,-105,-109,-115,-121,-121, 180, -60; /M: SY='A'; M= 97, 15,-100, -93,-108, -83,-102, -99, -95,-101, -95, -94,-100, -92,-100, 10, -84, -86,-110,-104; /M: SY='V'; M= -12, -99,-113,-107, -87,-112,-111, -16,-104, 1, 26,-108,-110,-105, -43, -46, -36, 92,-117, -94; /M: SY='S'; M= 14, -16, -91, -93, -39, 13, -94,-105, -92, -59,-101, -3, -99, -86, -97, 96, -74, -98,-113, -99; /M: SY='T'; M= -3, 60, -99,-100, -96,-103,-104, -4, -97, -50, 13, -31,-101, -99,-103, -5, 83, 37,-119, -98; /M: SY='V'; M= -7, -99,-115,-109, -87,-114,-117, 8,-107, -30, -75,-110,-111,-108,-109, -98, -84, 98,-118, -94; /M: SY='M'; M= -49, 15,-106, -99, -88, -56, -90, -75, -95, 0, 127, -94,-101, 7, -96, 22, 25, -43,-108, -87; /M: SY='T'; M= -81, -93, -89, -92,-100, -96, -98, -91, -89, -96, -93, -78, -92, -91, -97, 44, 110, -41,-119, -97; /M: SY='R'; M= -99,-115, -95, -83,-107,-109, -84,-114, -55,-107, -96, -88,-107, -71, 121, -93, -97,-108,-107, -94; /M: SY='Q'; M= -91,-112, -88, -43,-108, -52, -85, 31, -78, -93, -85, 20,-100, 119, -79, -46, -90, -4,-106, -93; /M: SY='N'; M= -94, -99, -67, -88,-108, -82, -74,-108, -79,-115,-101, 130,-105, -81, -88, -76, -78,-110,-128,-104; /M: SY='Q'; M= -26,-105, -44, -18, 11,-102, 23, -58, 12, 29, 33, 24, 11, 56, -20, -26, -10, -29,-104, -30; /M: SY='I'; M= -92,-104,-117,-113, -46,-120,-116, 90,-109, -4, -69,-109,-108,-107,-111,-103, -88, 63,-109, -89; /M: SY='P'; M= -97, -15, -99, -88,-114, -46, -11,-101, -50, -77, -99,-103, 125, -45,-105, -95, -91, -28,-111,-111; /M: SY='S'; M= -7, 5, -11, -91, 1, -4, 12, -59, -44, -26, 5, -84,-100, 19, -49, 63, 33, 1, -8, -25; /M: SY='P'; M= 7,-106, -85, 44,-105, -13, -29, -59, -1, -49, -96, 0, 46, 15, -8, 34, 19, -99, 4, -16; /I: I=-13; MD=-32; /M: SY='D'; M= -59,-113, 55, 36,-109, 3, -18, -52, -16, -49, -3, 32, 19, -20, -21, -39, -30, -33, 10, -23; D=-13; /I: I=-13; MD=-32; /M: SY='N'; M= -4,-122, 9, -27,-125, -3,-109,-118, -54, -74,-116, 38, 20, -6, -62, 4, -29, -32, 5,-118; D=-13; /I: I=-13; MI=0; MD=-32; IM=0; DM=-32; /M: SY='D'; M= -37, -12, 20, 1,-127, 8, -22,-123, -30, -30, -17, -33,-122, -13, -26, -7, -34, -58,-136,-121; D=-13; /I: I=-13; DM=-32; /M: SY='G'; M= 19,-112, -33, 24, -39, 46, -99,-109, -9, -58,-103, -3, 17, 8, -99, -11, -96, -34,-111, -3; D=-13; /I: I=-13; DM=-32; /M: SY='M'; M= -18,-112, 6, 12, -41, -18, -97, -52, -16,-102, 60, 4, 56, -24, -29, 25, -11, -66,-116,-103; D=-13; /I: I=-13; DM=-32; /M: SY='Q'; M= 0, -44, -6, 23,-109, -20, 16, 7, 29, -42, -95, -5, 19, 36, 10, -26, -57, -35,-114,-101; D=-13; /I: I=-13; DM=-32; /M: SY='M'; M= -49, -33, -39, -41, 14, -26, -9, -88, -19, 10, 69, 3, -7, 21, -39, 24, 28, -35,-109, -91; D=-13; /I: I=-13; DM=-32; /M: SY='I'; M= 21,-102, -41, 12, -35, -50, -19, 54, -60, -26, -80, -51,-101, 8, -99, -6, 18, 36,-107, -5; /M: SY='P'; M= -24,-103,-101, -97, -85,-104, 3, -54, -51, 56, 41, 8, 58, -95,-100, -22, 24, -41,-105, 10; /M: SY='A'; M= 82, 80,-101, -96, -37, -5,-103, -96, -97, -98, -94, -93,-102, -95,-102, 12, -84, -11,-111,-102; /M: SY='L'; M= -99,-101,-116,-108, -15,-117, -99, -64,-109, 93, 14,-115,-115,-102,-106,-109, -95, -71,-101, -83; /M: SY='I'; M= -95,-108,-117,-115, -81,-121,-117, 108,-110, -64, -6,-108,-106,-107,-113,-105, -89, 15,-106, -88; /M: SY='P'; M= -98,-123, -98, -87,-118, -57,-101,-106, -95,-116,-102,-104, 130, -98,-107, -95, -91,-111,-111,-115; /M: SY='L'; M= 0,-101,-111,-107, 57, 14, -15, -38,-105, 59, 42,-104,-110,-102,-105, -98, -94, -5, -95, -14; /M: SY='W'; M=-104,-120,-128,-111, 1,-108,-119, -89,-105, 32, 26,-122,-112,-103,-106,-112,-110, -99, 165, -64; /M: SY='D'; M= -99,-113, 123, -62,-120, -96, -85,-118, -86,-116,-115, -67, -98, -86, -95, -87, -89,-115,-135,-102; /M: SY='M'; M= -94,-101,-115,-105, 22,-108, -88, -68,-100, 14, 140,-103,-105, -92, -98, -43, -92, -75,-101, -78; /M: SY='C'; M= 50, 119,-108,-105, 28, -37,-107, 2,-103, -91, -21, -98,-110,-105,-107, -26, -89, -11,-111, -95; /M: SY='N'; M= -94, -99, -67, -88,-108, -82, -74,-108, -79,-115,-101, 130,-105, -81, -88, -76, -78,-110,-128,-104; /M: SY='H'; M=-101,-113, -85, -85, -98,-103, 152,-117, -90,-100, -85, -75,-102, -79, -84, -90, -99,-117,-132, -21; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='E'; M= 33, 8, -15, 53,-108, -52, -29,-104, 4,-103, -35, -37, -95, -14, 19, 37, 33, -64,-112,-100; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='N'; M= -49,-107, 26, 39, -12, -44, 37, -16, -24, -60, -30, 72, 18, 28, -40, -2, -37,-101,-114, -95; /M: SY='G'; M= -11,-106, -42,-103,-113, 97, -20,-116, -99,-114,-104, -82, -51, -96,-106, 7, -95, -59,-107,-107; /M: SY='Q'; M= -50,-110, 11, 15,-106, -28, 24, -25, 38, -40, -94, 5, 47, 48, 17, -24, 3, -51,-110, -42; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='I'; M= -51,-104,-111, -54, 28,-113,-103, 73,-104, 20, 58, -34,-107, -35,-106, -47, -34, 26,-101, -21; /M: SY='T'; M= -32, 44, -90, -45,-101, -34, -25, -45, -26, -44, -94, -12, -41, -31, -36, 57, 83, -89,-116, -98; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='T'; M= -43, -10, -93, -94, -32, -99,-100, -84, -92, -92, -90, -83, -28, -94, -99, 28, 102, 25,-117, -96; /M: SY='D'; M= -16, 26, 77, -19, 41, -6, 36,-102, -91, -99, -97, 17,-103, 6, -95, -17, -90, -47,-102, 40; /M: SY='Y'; M= -57,-107,-109,-108, 93,-109, -84, -36,-103, -79, -83,-104,-114,-103,-100, -4, -95, -44, 9, 101; /I: I=-38; MD=-97; /M: SY='D'; M= -34,-105, 81, -36,-110, -89, -30, -68, -39,-112,-105, 80,-101, -84, -92, 42, -82, -66,-124, -33; D=-38; /I: I=-38; MD=-97; /M: SY='P'; M= 1,-109, 1, 14, -33,-105, -10, 11, -31, -16, -91, -96, 64, -25,-101, -14, 25, 15,-114,-100; D=-38; /I: I=-38; MI=-97; MD=-97; IM=-97; DM=-97; /M: SY='E'; M= -10,-108, 4, 67,-109, -7, -93, -45, 8, -69, -11, -36, -97, 46, -87, -19, -9, 17,-113,-101; D=-38; /I: I=-38; DM=-97; /M: SY='T'; M= -24,-102, 33, 29, -47, -22, -91, -65, 4, -25, -95, 9, -96, 22, -27, 38, 52, -38,-113, -97; /M: SY='D'; M= -94,-110, 80, 14,-108, -24, 9,-110, 2,-108,-101, 25, -99, 42, 32, -4, -89, -55,-114, 2; /M: SY='C'; M= -24, 86, -93, 0,-101, -24, -93, -41, -83, -97, -30, -16,-104, 51, 40, 39, -35, 13,-111, -6; /M: SY='C'; M= 33, 56,-104,-100, -90, -31,-101, 23,-100, 38, 27, -96,-105, -18,-102, 35, -26, -3,-109, -94; /M: SY='E'; M= -91, -15, -42, 88,-102, -61, 9, -10, -16, -21, -91, -91, -95, -14, -7, -50, -11, 27,-113, -98; /M: SY='C'; M= -91, 123,-107,-107, 37,-105,-105, 19,-104, -10, -88, -52,-113,-105,-108, 33, -15, -27,-110, -46; /M: SY='Y'; M= -43, -19, -15, -99, 35, -51, 12, 0, -47, 27, 0, -96, -31, -45, -98, 3, 23, -18, -88, 75; /M: SY='A'; M= 94, 18, -99, -92,-105, -83,-100, -96, -94, -37, -92, -92, -99, -91, -99, 13, -11, -84,-109,-102; /M: SY='M'; M= -18, -8, -54, -95, -13, -20, -18, -6, -18, 3, 100, 1, -5, 25, -35, -9, -41, 2, -22, -88; /M: SY='K'; M= -7, 12, -36, 25, -49, -69, -88,-108, 63,-105, -97, -1, -98, 32, 61, -19, -16, -73,-108, -97; /M: SY='D'; M= 18,-104, 72, 24,-112, -41, -87,-109, -44,-111,-104, 53, 11, -82, -38, 38, -34,-104,-119,-102; /M: SY='F'; M= -33, 7,-112,-110, 93,-111, -93, -5,-105, -20, -80,-105,-113,-108,-104, -99, -10, 12, 13, 74; /M: SY='K'; M= 14,-106, -23, -1,-110, -63, -90,-105, 73,-106, -97, -8, 16, 32, 7, 28, -42, -44,-108, -99; /M: SY='A'; M= 60, -16, -55, -28,-107, -92, -97, -53, 50, -57, -93, -89, 47, -1, -84, -8, 17, -36,-109,-101; /M: SY='G'; M= -83,-107, -9, -62,-113, 97, -97,-118, -97, -72,-105, 34,-100, -95,-105, -38, -43,-113,-108,-108; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='E'; M= -61,-109, 59, 92,-114,-100, -86,-113, -40,-109,-105, -32, -91, 3, -86, 14, -10,-107,-116,-103; /M: SY='Q'; M= -91,-115, -83, 40,-116,-100, -83,-108, -75,-104, -93, -85, 33, 119, -78, -40, -23,-108, 32, -95; /M: SY='V'; M= -91,-102,-116,-112, 23,-118,-113, 70,-109, 10, -70,-110,-110,-108,-110,-102, -87, 74,-106, -85; /I: I=-18; MD=-45; /M: SY='F'; M= -97,-103,-102,-102, 82,-107, -90, -86, -27, -13, -17, -16,-107, -99, -4, -27, 59, -88, -84, 65; D=-18; /I: I=-18; MI=0; MD=-45; IM=0; DM=-45; /M: SY='I'; M= -44,-107,-117,-113, -6,-117,-107, 95,-107, -41, 89,-106,-105,-103,-109,-103, -39, -58,-104, -85; D=-18; /I: I=-18; DM=-45; /M: SY='F'; M= -59, 32, 10,-100, 82,-107, 52, -43, -99, -84, -12, -95,-111, -99, -45, 5, -36, -26, 7, 71; D=-18; /I: I=-18; DM=-45; /M: SY='Y'; M=-103,-114,-102,-106, -52,-110, -70, -89, -98, -86, -82,-104,-115, -93, -95, -97, -31, -94, -60, 137; D=-18; /I: I=-18; DM=-45; /M: SY='G'; M= -81,-108, -96,-108,-115, 104,-103,-122,-102,-118,-107, -82,-100, -99,-109, -51, -32,-115,-106,-110; D=-18; /I: I=-18; DM=-45; /M: SY='P'; M= -17, 14, 22, -26, -34, -96, -3,-104, 27,-106, -35, 39, 51, -39, 28, 22, -14, -45, -2, -25; D=-18; /I: I=-18; DM=-45; /M: SY='R'; M= -99,-116, -96, -84,-108,-110, -84,-115, -56,-107, -96, -89,-108, -72, 120, -94, -98,-109,-108, -95; D=-18; /I: I=-18; DM=-45; /M: SY='S'; M= -83, -22, -39, -90,-107, -9, -95,-102, -91,-107,-100, 11, 63, -89, -98, 69, 66, -97,-116,-103; D=-18; /I: I=-18; DM=-45; /M: SY='N'; M= -27, -31, -33, -89,-109, -55, -79,-108, -82,-114,-102, 118,-104, -83, -42, 23, -32,-107,-125,-103; D=-18; /I: I=-18; DM=-45; /M: SY='A'; M= 58, 3, -44, -22,-100, 0, -95, -44, -89, -55, 2, -45,-100, -27, 9, 49, -10, -51, 1, 3; D=-18; /I: I=-18; DM=-45; /M: SY='D'; M= -30,-112, 86, 71,-115,-100, 21,-113, -81, -58,-104, -28, -95, 38, -88, -45, -91,-109,-121,-100; D=-18; /I: I=-18; DM=-45; /M: SY='F'; M=-103,-104,-114,-108, 91,-115, 22, -76,-104, 53, 30,-107,-115, -48, -15,-105, -98, -82, -86, 3; D=-18; /I: I=-18; DM=-45; /M: SY='F'; M=-102,-103,-118,-111, 82,-117, -99, -36,-110, 71, 12,-113,-116,-108,-107,-108, -97, -54, -89, -13; D=-18; /I: I=-18; DM=-45; /M: SY='L'; M= -94,-102,-116,-110, -15, -56,-107, 41,-109, 65, 11,-111,-112,-105,-108,-105, -54, 47,-106, -87; D=-18; /I: I=-18; DM=-45; /M: SY='H'; M= -53, -8, -91, -92, 6,-104, 130,-104, -93, -60, -10, 6,-106, -85, -89, -93, -98,-106, -99, 75; D=-18; /I: I=-18; DM=-45; /M: SY='N'; M= -52, -9, -76, -88,-106, -84, -81,-106, -84,-110, -20, 104,-102, 15, -90, 65, -76,-104,-119, -27; D=-18; /I: I=-18; DM=-45; /M: SY='G'; M= -44,-109, -96, -46,-115, 104,-103,-122,-101,-118,-107, -83,-100, -99,-109, -82,-100,-115,-106,-110; D=-18; /I: I=-18; DM=-45; /M: SY='F'; M=-107,-103,-120,-115, 126,-115, -99, -80,-110, -72, -82,-108,-118,-121,-107,-106, -99, -86, -72, -50; /M: SY='V'; M= -48, 46,-111,-106, -3,-110,-112, -11,-104, -41, -78,-104,-109,-105,-107, 14, -48, 93,-115, -91; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='P'; M= -28, 37, 13, -17, 29,-104, -36, -91, -96, -3, -29, -44, 80, -26,-100, -95, -92, -29, -91, 72; /M: SY='P'; M= 12,-110, 15, 53,-109, -99, -14, -25, -23, -73, -16, -91, 85, -4, -94, -28, -17, -23,-112,-103; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='N'; M= -92,-106, 57, 44, -36, -12, 27,-103, -16,-105, -99, 57, -32, 17, -29, -26, 18, -14,-118, -97; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='N'; M= -56,-100, -36, -44,-108, -45, 38,-108, -81,-113,-100, 119,-103, -81, -89, 7, -33,-108,-126,-100; /M: SY='P'; M= -10,-108, -1, 39,-106,-100, -30, -33, -3, -25, -93, -90, 74, 10, -8, -1, 22, -7,-112,-101; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='H'; M= -28,-106, -85, -8, 27, -47, 85,-101, 0, -97, -90, 67,-104, -13, -46, -39, -39,-102, -93, 76; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='D'; M= -98, -18, 113, -45,-114, -51, 14,-115, -47,-114,-110, 24, -99, -85, -93, -56, -41,-112,-129, -27; /M: SY='S'; M= 13, -9, -32, -91, 11, -25, -14, -31, -13, -95, -11, -7, -12, -26, 35, 44, 8, -5, 3, 31; /M: SY='Y'; M= -49, -22,-111,-107, 23,-113, -95, 20,-103, 22, -1,-107,-111,-102, -41, -99, -37, 60, -89, 77; /M: SY='K'; M= -20, -7, -10, -11,-105, -54, -91,-102, 63, -25, -36, 17, 30, 9, 21, 13, -7, -51, 32, -97; /M: SY='I'; M= -96,-104,-116,-111, -3,-119,-108, 77, -51, 59, -65,-110,-110,-105,-108,-106, -91, 16,-103, -85; /M: SY='K'; M= -63,-109, -31, -18,-103,-102, 6, -44, 65, -59, -93, -36, 15, 6, 61, -6, -16, -1, 10, -45; /M: SY='L'; M= -97,-102,-116,-109, 8,-117,-102, 35,-109, 76, 39,-112,-113,-103,-107,-107, -93, 15,-102, -83; /M: SY='G'; M= -26, -11, -31, -29,-110, 82, -98, -62, -93,-110,-102, -82, -11, -25, -14, 40, -17, -51,-109,-105; /I: I=-24; MI=0; MD=-60; IM=0; DM=-60; /M: SY='I'; M= -50,-102,-115,-110, 23,-117,-106, 58,-108, 58, -67,-110,-111,-105,-108,-103, -38, 40,-101, -23; /I: I=-33; MI=0; MD=-84; IM=0; DM=-84; /M: SY='S'; M= -22,-102, -14, -35,-108, 14, -94, -51, -89,-107, -99, 4, 57, -28, -31, 77, -1, -28,-113,-102; /I: I=-33; MD=-84; /M: SY='K'; M= -93,-111, -8, -41,-112,-100, 6,-110, 83, -70, -99, -27, 40, 22, -3, 24, -52,-107,-110, -99; D=-33; /I: I=-33; MD=-84; /M: SY='S'; M= 3,-101, 4, -19, -12, -36, -18,-102, -5, -62, -99, 42, -29, -26, -92, 67, 26, -40,-115, -98; D=-33; /I: I=-33; MI=-84; MD=-84; IM=-84; DM=-84; /M: SY='D'; M= -57,-112, 114, -45,-115, -97, -87, -53, -88, -34,-109, -22,-101, -87, -34, -13, -89,-109,-131,-102; D=-33; /I: I=-33; DM=-84; /M: SY='P'; M= -24,-114, -31, -15,-113, -55, -95, -48, 44,-110,-100, -32, 91, 13, 12, 8, -89, -49,-111,-105; D=-33; /I: I=-33; DM=-84; /M: SY='L'; M= -49,-102, -40, -44, -11,-110, 8, -15,-101, 79, -68, 33,-112, -32, -51,-100, -43, -77,-106, -86; D=-33; /I: I=-33; DM=-84; /M: SY='Y'; M= 0, -13,-101, -53, 56,-104, 23, -5, -59, -8, -14, 4,-108, 2, -7, -8, -91, 14, 13, 67; /M: SY='K'; M= 19,-105, 14, 35, -36, -27, 15, -48, 52, -65, -96, 7, -31, 37, -79, 18, -17, -99,-110, -96; /M: SY='K'; M= 17,-104, 4, 26, -35,-102, -93, -22, 44, 30, 30, -91,-100, 24, -26, -23, -44, -31, 16, -92; /M: SY='R'; M= -97,-112, -91, -78,-109,-105, -86,-113, 81,-108, -96, -84,-101, -71, 95, -91, -93,-107,-106, -95; /I: I=-42; MD=-106; /M: SY='T'; M= 32, -7, -96, -43, -97, -26, 13, -3, -2, -5, -24, -28,-101, 14, -37, 20, 39, 17,-111, -41; D=-42; /I: I=-42; MI=-106; MD=-106; IM=-106; DM=-106; /M: SY='Q'; M= 15,-107, 3, 29,-105, -49, 39,-102, 33, -18, 28, -30, -99, 44, 25, 13, -38, -99,-111, -94; D=-42; /I: I=-42; DM=-106; /M: SY='L'; M= -55,-101,-114,-105, -77,-116,-102, 20,-105, 77, 10,-110,-112, 0, -49,-104, -92, 33,-106, -87; /M: SY='L'; M= -44, 39,-115,-108, 9,-115, -99, -16,-108, 80, 44,-111,-114,-103,-106,-105, -94, -19,-101, -22; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='Q'; M= 3, 7, -14, 29,-107, -19, 5,-104, 41, -66, -95, -31, -28, 56, -3, 19, 18, -50,-109, -28; /M: SY='K'; M= -29,-107, 11, 2, -44,-102, -90, -97, 76, 8, 18, -35, -99, -78, 43, -28, -26, -65, 11, -93; /M: SY='L'; M= -15, -5,-110,-105, 17,-111, 4, 9,-102, 67, 57, -40,-111, -98, -21,-101, -39, -30, -99, 14; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='G'; M= -39,-105, 6, 1,-108, 69, 0,-110, -11,-110,-101, 43, -99, -36, -15, 19, -5, -48,-110, -24; /M: SY='L'; M= -51,-102,-115,-109, 41,-115,-101, 45,-107, 57, 40,-109,-111,-104,-106, -63, -92, 24, -96, 17; /M: SY='P'; M= -5,-106, -42, -9, -38, -38, -32, -67, 7, -42, -95, 18, 69, 38, -16, 32, 17, -32,-110, -99; /M: SY='S'; M= 32, -16, -51, 6,-100, -48, -25, -60, -35, -27, 27, -13, 24, -88, -38, 44, 36, 13,-113, -98; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='S'; M= -25, -11, 3, 13,-104, -43, -90, -49, -46, -45, -96, 33, 9, 9, -92, 74, 16, -27,-114, -47; /M: SY='G'; M= -13, 9, -90, -10, -6, 61, -94, -23, -62, -42, -96, 23,-100, 29, -13, 30, 11, -98,-107, -98; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='D'; M= -50,-105, 37, 23, -94, -98, 23, -47, -25, -6, -41, 34, -54, 19, -16, 15, 28, -18, 11, 34; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='F'; M=-102, -19, -42,-110, 99,-114, -95, -3,-107, 26, -76,-107, -34,-110,-105,-104, -96, -10, -79, 53; /M: SY='Q'; M= -5, 21, 19, -3, -56, -97, 43, -41, -44, -35, -31, 11, 5, 49, -5, 31, -28, 1,-108, 19; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='L'; M= -95,-102,-116,-110, -76,-118,-107, 50,-109, 71, -64,-113,-112,-105,-108,-106, -91, 42, 14, -86; /I: I=-25; MD=-63; /M: SY='H'; M= -51, 6, 7, -92, -35, -20, 36, -46, -2, -3, 7, 27, -18, -89, 14, 28, 25, -61,-108, 27; D=-25; /I: I=-25; MD=-63; /M: SY='P'; M= 11, 30, -94, -39, -58, 10, 9, -57, 24, -35, -97, -4, 37, 25, -11, 35, -42, -48,-112,-101; D=-25; /I: I=-25; MD=-63; /M: SY='G'; M= -34, -36, 31, -4,-116, 46, -99,-114, -31, -79, -34, 40, -15, -30, -55, 7, -28, -42,-120, -33; D=-25; /I: I=-25; MI=0; MD=-63; IM=0; DM=-63; /M: SY='D'; M= -34,-110, 43, 26,-108, 1, -38, -26, -40, -72, -17, -87, 40, -90, -65, 41, 11, -17,-116, -24; D=-25; /I: I=-25; DM=-63; /M: SY='P'; M= -50, -2, 22, 20, -22, 3, 18, -99, -17, 4, -11, 15, 33, 17, -27, 10, -8, -51,-113, -97; D=-25; /I: I=-25; DM=-63; /M: SY='P'; M= -95,-113, -96, 10, 7, -36, -22, -21, -16, -25, -12, -97, 89, 4, -36, 0, -2, -41,-104, 13; D=-25; /I: I=-25; DM=-63; /M: SY='I'; M= -32,-105,-110, -46, 27,-113,-107, 65,-105, 32, -17, -33, 25,-104,-108,-100, -7, 26,-104, -86; D=-25; /I: I=-25; DM=-63; /M: SY='S'; M= -30,-104, 55, -23,-108, -6, 28,-106, -89, -46,-100, -29, 46, -23, -54, 67, 12,-102,-117, -99; /I: I=-38; MD=-97; /M: SY='P'; M= -11,-111, -8, 37,-112, 12, -96,-104, -8, -51,-100, -15, 73, -33, -8, 10, -3, -28,-114,-106; D=-38; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='E'; M= -13, -1, 45, 53,-107, -62, -87, -46, -16, -22, -16, 13, -30, 46, -34, 37, -35, -99,-114, -99; /M: SY='L'; M= -13,-101, -41,-105, -21,-113, -98, -30,-106, 84, 37,-110,-113,-100,-105,-103, -53, -38,-100, -2; /M: SY='L'; M= -29,-103,-109, -28, 13,-112,-101, 42,-100, 62, 20,-106, -34, -27, -7, -59, -13, -13, 6, -84; /M: SY='A'; M= 58, -9, -40, 4,-100, 1, 6, -10, -88, -15, -18, -39, -27, -29, 27, -13, -12, -8,-109, -35; /M: SY='F'; M= -53,-104,-115,-110, 117,-112, -97, -83,-106, -49, -83,-106,-114, -8,-104,-101, -11, -87, 44, 22; /M: SY='L'; M= 46, -15, -41, -99, -86,-100, -37, -8,-101, 48, -76,-100, -24, -97,-103, -7, 9, 33,-107, -18; /M: SY='R'; M= -16,-112, -94, -81,-107,-105, -11,-106, 19, -60, -93, -87,-105, 32, 105, -90, -95, -29,-107, -94; /M: SY='V'; M= -55,-102, -32,-109, -83,-117,-113, 72,-107, 9, -11,-108,-108,-106,-109,-101, -87, 75,-112, -90; /M: SY='F'; M= 3,-102, -42,-105, 98,-107, -19, -28,-103, 20, -11, -31,-112, -28,-103, -34, -36, -55, -83, 26; /M: SY='C'; M= 17, 62, -97, -99, -94, -98, -31, -2, -53, -24, -10, 51,-106, -96,-100, 19, -6, 56, 10, -96; /M: SY='M'; M= 15, -16,-109,-102, -14,-101, -15, -40, -98, 15, 125, -99,-103, -91, -98, 12, -38, -78, 22, -83; /M: SY='N'; M= -92,-105, 64, -39,-109, -94, -85,-103, 2, -62, -5, 69, 26, 25, -12, -8, 37, -66,-119,-100; /M: SY='E'; M= -10,-107, 4, 62,-110, -99, -89, -60, 59, -60, -98, -38, 20, 20, -44, 9, 0, -64,-110,-100; /I: I=-8; MD=-20; /M: SY='E'; M= -5,-113, 58, 61,-116, -19, -92,-109, -9, -78,-104, -34, 48, 21, -91, -57, -39, -34,-117,-106; D=-8; /I: I=-8; MD=-20; /M: SY='E'; M= -49,-113, 16, 64, -45, -31, -41,-113, -17,-111,-105, 15,-100, 59, -90, 10, 0, -54,-118,-104; D=-8; /I: I=-8; MD=-20; /M: SY='L'; M= -34,-112, -40, -46, -88,-124,-111, -4,-116, 71, -12,-120, -43,-111,-116,-113, -36, -26,-116, -99; D=-8; /I: I=-8; MD=-20; /M: SY='D'; M= -13,-117, 39, 24,-118, -53,-100, -56, 5, -60, -31, 7,-109, 28, 4, -49, 5, -14,-125,-109; D=-8; /I: I=-8; MD=-20; /M: SY='H'; M= -16,-118, 7, 2, -38,-111, 64, -12, 23, -62,-101, -51, -42, 19, -16, -11, 0, -57,-120, -15; D=-8; /I: I=-8; MD=-20; /M: SY='W'; M= -2, -22,-125, -48, -34,-118, -39, -24, -74, 15, -13,-121,-121,-110, -45,-112, -45, -33, 120, 37; D=-8; /I: I=-8; MD=-20; /M: SY='L'; M= -14,-118,-124, -27, -41,-127,-117, -6,-120, 53, 20, -37,-126,-115,-121, -67, -30, -28,-123,-105; D=-8; /I: I=-8; MI=0; MD=-20; IM=0; DM=-20; /M: SY='D'; M= 2, -5, 17, 5, -54, -64, -9,-130, -19,-130,-123, 1,-125, 15, -11, -31,-113, -57,-139,-122; D=-8; /I: I=-8; DM=-20; /M: SY='H'; M= 8,-119, -39, -60, -45, -26, 23, -13, 3, -28, 1, 18, -34,-102, -3, 7,-102, -37,-126,-109; D=-8; /I: I=-8; DM=-20; /M: SY='T'; M= 14, 5, 20, 18, -6, -55, 24, -53, 5, -16, -19, -3, 23, 13, 5, -18, 28, -96,-111, -94; /M: SY='A'; M= 31, -14, 9, -8, -99, -61, 8, 5, 17, -44, -19, 30,-100, -86, -51, 31, 22, -28,-111, -1; /M: SY='D'; M= 6,-107, 64, 48, -54, -28, -89, -54, -52,-106,-101, -1, -37, 35, -42, 27, -6, -29,-116,-100; /M: SY='N'; M= 16, -41, -13, 29,-105, -13, -19, -28, 9, -26, -93, 35, 8, 29, 25, -42, 3, -32,-111, -44; /M: SY='T'; M= 21, -29, -35, -95, -95, -55,-100, 25, -11, 12, -17, -30, 23, -92, 4, 28, 29, -6, -14, -96; /M: SY='S'; M= 28,-103, -16, 8, -3, -6, 2, -7, 4, -28, 25, -18,-100, 18, -52, 44, -25, -48, -12, -93; /M: SY='D'; M= 25, -32, 59, 19,-110, -37, -29,-105, -1,-105, -16, 15, -98, 14, -7, 22, 21, -54,-117,-100; /I: I=-15; MD=-38; /M: SY='L'; M= -22,-105,-110, 0, -83,-116, -21, 20, -48, 69, 23,-110,-112, -33,-104, -64, -95, 2,-109, -91; D=-15; /I: I=-15; MD=-38; /M: SY='M'; M= -32, -21,-106, -13, -17, -7,-102, -42, 1, 27, 32,-101,-111, -12, 16, -3, 3, -6,-111, -24; D=-15; /I: I=-15; MD=-38; /M: SY='H'; M= -44,-112, 9, -1, -47,-104, 67,-108, -8, -31, -22, 27, -28, 14, 0, 23, 8, -56, -11, -52; D=-15; /I: I=-15; MD=-38; /M: SY='S'; M= -43,-113, -43, 12, -24,-108,-102, 6, -29, -27, -97, -42, 11, -27, -27, 40, 9, -12, 13, 25; D=-15; /I: I=-15; MD=-38; /M: SY='D'; M= -31, -20, 78, 22, -37,-107, -18,-119, 7,-118,-114, -1, -9, -92, -45, -20, -52, -56,-128, -44; D=-15; /I: I=-15; MD=-38; /M: SY='C'; M= -32, 83, -2, 5, 34, -38, -17, -24,-107, -29,-102, 9,-119, -51, -44, -51, -28, -19,-120,-100; D=-15; /I: I=-15; MD=-38; /M: SY='A'; M= 33, -15, -5, -31, -56, -68,-109, -33, 2, -65, -37, 1, 26,-102,-105, -7, 11, -34, 31,-109; D=-15; /I: I=-15; MD=-38; /M: SY='L'; M= -37,-118,-125,-120, -13, -52, -14, 11, -57, 33, -89,-119, -39,-116,-119, -9, -68, 26,-120, -17; D=-15; /I: I=-15; MI=0; MD=-38; IM=0; DM=-38; /M: SY='D'; M= -57,-118, 58, 11,-119, -27, 11,-117, -20,-118, -23, -23, -9, -94, -20, 36, -27, -45,-127, -29; D=-15; /I: I=-15; DM=-38; /M: SY='T'; M= -4, -17, 25, 18, -24,-106,-101, -53, -33, -19,-101, -2, 31, -3,-102, -5, 42, -53, -14,-104; D=-15; /I: I=-15; DM=-38; /M: SY='E'; M= 13,-113, 42, 54, -36, -42, -16,-108, -8, -32,-102, -91, -8, 12, -2, -31, -30, -38,-118,-104; D=-15; /I: I=-15; DM=-38; /M: SY='N'; M= -69, 31, -36, -6, -31, -53, 8, 4,-100, 31, -86, 58,-112, -46,-104, -1, -44, 12, 9, -96; D=-15; /I: I=-15; DM=-38; /M: SY='E'; M= -8, 10, 48, 72,-110,-107, -18, -51, -58, -24, -19, -30,-101, -25, -28, -46, -39, -6,-120,-104; D=-15; /I: I=-15; DM=-38; /M: SY='Q'; M= -7, -20, 11, -27,-104, -21, -93, -31, 34, -15, -42, 15, -55, 37, 12, -9, 33, -19,-112, -39; D=-15; /I: I=-15; DM=-38; /M: SY='K'; M= -7,-108, -89, -16,-109, -49, -11,-105, 90, -76, -96, -47, -98, -2, 37, -9, -89, -20,-107, -97; /M: SY='A'; M= 63, 19,-103, -99, -34, -28,-105, 14, -98, -45, -86, -96,-103, -97, -41, 5, 11, 42,-110, -44; /M: SY='W'; M= -53, -36, -45,-104, 16,-110,-105, -2, -22, 35, -13, -35,-111, -98, 12,-105,-101, -31, 136, 16; /M: SY='Q'; M= 3,-105, 17, 25,-109, -35, -27,-105, 30, -49, -23, 51, -98, 53, -4, 14, -5, -68,-113, -99; /M: SY='F'; M= -57,-107, -46,-111, 108, -53, -96, -84,-107, -13, -84,-108,-117, -28,-105,-104,-100, -89, 56, 55; /M: SY='L'; M= -57,-103,-113, -44, -36,-117, -12, 5,-107, 82, -15,-111,-114, -28,-106,-106, -42, -5,-106, -87; /M: SY='H'; M= 5,-108, -40, 42, -21,-102, 59, -35, 39, -16, 12, -87, -99, 29, 15, 3, -40, -97,-109, -41; /M: SY='T'; M= 28,-101, 41, -89,-101, -51, -96, 15, -25, -31, 7, 35,-100, -92, -42, -39, 65, -39,-117, -99; /M: SY='R'; M= -98,-115, -37, -19,-110, -57, -86,-113, 0,-108, -97, -88,-106, -13, 110, -38, -97, -55,-109, -96; /M: SY='C'; M= -4, 76,-115,-110, 49,-113,-105, 23,-107, 49, -14,-109,-115,-107, -47,-102, -94, 8,-101, -26; /M: SY='Q'; M= -10,-105, -34, -13, -58, -24, -89,-100, 54, -35, 35, 14, -99, 58, -79, 25, 20, -98,-108, -28; /M: SY='L'; M= -47,-103,-114, -49, -77,-117, -37, 17,-109, 81, 0,-113,-114,-102,-107, -53, -94, 2,-106, -88; /M: SY='L'; M= -38,-103,-113, -45, -77,-116,-100, 8,-105, 82, 13,-111,-113, -27, -36,-105, -23, -73,-104, -28; /M: SY='L'; M= -32,-105,-104, -11, -31,-111, -19, 21, 0, 57, 28,-102, -38, 36, -38, -45, -53, -1,-106, -89; /M: SY='R'; M= 21,-106, -92, -19,-107, -39, -91,-104, 42, -27, -31, -30,-101, 7, 66, 29, 1, -99,-110, -98; /M: SY='S'; M= 40,-101, -96, -92, -35, -3, -13, -91, -19, -24, -11, -15, -34, 23, 0, 41, 15, 11,-111, -97; /M: SY='Y'; M= -57, 19,-105,-107, 24, -54, -13, -40,-101, 1, -81,-103,-114, -98, -99, -62, -6, -49, -71, 117; /M: SY='P'; M= -92,-111, 7, -2,-108, 18, -93,-105, 49,-109,-100, -12, 63, 8, -5, -14, 13, -29,-109, -7; /I: I=-45; MD=-115; /M: SY='T'; M= -24,-101, -92, -92,-105, -23, -97, -97, 19, -60, -12, 14, -12, -90, -1, 23, 83, -34,-117,-101; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='T'; M= -88,-101, -49, -26, -40, -37, -12, -4, -25, -1, 9, -17, -48, -3, -19, 41, 72, -53, 13, -94; /M: SY='L'; M= -31,-105, 0, -11, -6, -67,-100, 35, -14, 41, -1, -37, 0, -11, -36, -1, -3, -5,-108, -91; /M: SY='E'; M= 4, -19, 37, 61,-111, -53, -24,-104, 25, -42, -37, -34, -45, 42, -36, -29, -38, -16,-115,-101; /M: SY='E'; M= -10,-109, 22, 69,-113, -35, -91,-104, 7,-107,-101, 19, 4, 22, -88, 8, -27, -3,-116,-104; /M: SY='D'; M= -13, -9, 86, -24, -42, -29, -92, -21, -10, -24,-100, 1, -22, -35, -56, -47, -37, -26,-116, 7; /M: SY='E'; M= -27,-110, -13, 62,-104, -45, -94, -31, 23, -3, -15, -4, 18, -23, -41, -26, 21, -63,-112, -31; /M: SY='E'; M= -5,-108, -9, 39,-104, -30, -41, -99, 26, -4, -94, -16, 2, 19, -7, 15, 4, -16,-112, -24; /M: SY='L'; M= -7,-106, -44, 26, -55, -39, -97, 0, 3, 29, -29, 26,-105, -37, -96, 7, 5, -1,-112, -29; /I: I=-36; MD=-90; /M: SY='L'; M= -23,-110, -9, 6, -93,-113, -4, -55, -35, 49, 21, -40,-112, -29,-104, -10, 7, -10, 2, -27; D=-36; /I: I=-36; MD=-90; /M: SY='N'; M= 1,-113, 16, 17,-116, -52, -96,-109, 40, -67, -21, 46, -43, 14, -52, -16, -8, -28,-122,-108; D=-36; /I: I=-36; MD=-90; /M: SY='N'; M= -46, 2, -18, -7, -55, -19, -13, -1, 19, -70, -36, 26, -40, -5, -1, 0, 13, -33,-123,-107; D=-36; /I: I=-36; MI=-90; MD=-90; IM=-90; DM=-90; /M: SY='N'; M= 4,-112, 4, 19,-109, 5, -99, -29, -27, -11, -15, 26, 1, 23, -99, -19, 13, -54,-118, -38; D=-36; /I: I=-36; DM=-90; /M: SY='D'; M= -13,-109, 25, 16, -11, -25, -2, -99, -51, -12, -44, 14, 4, 4, 7, 12, 14, -13,-115, -46; /M: SY='M'; M= -4,-107, -44, -16, -9, -68, -23, -11, -32, 23, 41, 11, -17, 3, -4, 16, 2, -21,-112, -95; /M: SY='T'; M= -37,-108, -2, 3, -16, -1, -99, -3, -32, -22, -18, -25, 1, 30, -47, 22, 45, -24,-114, -99; /M: SY='H'; M= 10, 25, -24, -1, -37, -3, 30, -17, 2, -21, 2, -12, 10, 25, -5, -60, -10, -53, 1, -19; /M: SY='R'; M= -10,-111, -42, -90, -39, -50, 45, -32, 21, -19, -38, 17, -8, 13, 57, 5, -15,-102,-115, -96; /M: SY='R'; M= -6,-108, -52, 5, -97, -42, -37, -21, 13, 16, -13, 5,-106, 8, 18, -17, 11, -2,-110, 9; /I: I=-16; MD=-40; /M: SY='R'; M= -54, -21, -14, -27, -37, -58,-107, 4, 32, -14, -21, -45,-117, -49, 48, -46, -55, -26,-122,-107; D=-16; /I: I=-16; MD=-40; /M: SY='M'; M= -69, -27, -11, -17, -39,-133, -42,-116, -32, -6, 7, -35,-131, -48, 4, -48, 2, -37,-137, -49; D=-16; /I: I=-16; MI=0; MD=-40; IM=0; DM=-40; /M: SY='Y'; M= -4,-135, -20, -28,-123, -12,-121, -4, -16, -29,-117, -24,-131, -28, -21, -41,-119,-117,-132, -1; D=-16; /I: I=-16; DM=-40; /M: SY='M'; M= -14, -32, -43, -13, -32, -54, -10, -19, -46, 39, 71, 29,-110, -27,-100, 8, -93, -87,-108, 13; /M: SY='A'; M= 43, 29, -47, -14, -21, -75,-107, 19, 3, 9, -86,-102,-109, -26, -54, -33, -92, 30,-113, -98; /M: SY='I'; M= -16, -10,-108, -12, -43,-115, -15, 47, -12, 36, -11, -42,-111, -99, -1, -43, -44, 21,-112, -94; /M: SY='Q'; M= -23,-112, -92, 25, -35,-106, -28, -15, 22, 0, -91, 7,-105, 72, 15, -32, -37, -34,-109, -19; /M: SY='M'; M= -53, -28, -41, -33, -13,-116, -96, 19,-106, 55, 58,-109,-114, -9,-105, -55, -41, -80, -98, 54; /M: SY='R'; M=-101,-114, 0, -28,-103, -54, -15, -43, 18, 16, -91, -30, -36, -27, 83, -98, -48, -29,-114, -98; /M: SY='M'; M= 13, -10, -57, -57, 16,-108, -32, 15, 1, 25, 28, 21,-111, -24, 3, -98, -94, 11,-110, -92; /M: SY='C'; M= -9, 47, -55, -11, -99, -9,-102, -7, -50, 0, -15, -7, -36, 0,-103, 29, 8, 20, -7, -26; /M: SY='E'; M= -14, -13, -76, 94, -49,-107, -93, -50, -46,-109,-106, -38, -96, 2, -25, 0, -95,-108, 41,-103; /M: SY='K'; M= -98, -11, -35, -18,-110,-106, 20, -39, 71, -73, -35, 5, -9, -2, 32, -8, -23, -53,-113, -24; /M: SY='R'; M= -15, -37, 13, 20, -40,-107, -95, -10, 27, -26, -98, -19,-106, 34, 38, -2, -23,-101,-112, -10; /M: SY='I'; M= -52, -16, -61,-114, -19,-121,-115, 77,-111, 5, -79,-111,-114, -28, -40, -33, -28, 11, 11, -11; /M: SY='L'; M= -46,-109, -43, -26, -44,-120,-106, -23, -26, 75, 9,-114,-118,-104, -42, -58,-100, -43,-111, -94; /M: SY='Q'; M= -7,-114, -42, 25, -57,-108, -98, -25, 25, -13, -32, 19,-108, 38, 6, -3, -26, -32,-118,-105; /M: SY='S'; M= -18,-113, 13, 8,-114, -45, -20,-111, 6, -41,-105, 34,-108, -8, 22, 36, -23, -40,-122, -41; /M: SY='A'; M= 41, 6,-107, -42, -20, -52, -16, 0,-104, -21, -15, 7, -51,-103, -47, -35, 15, 1, 6, 3; /M: SY='L'; M= -8,-113, -57,-112, -11,-120, -11, 16, -13, 48, -1,-114, -37,-109,-110, -49, -45, 0,-114, -24; /M: SY='E'; M= -3,-116, 16, 57, -20,-108, -11,-113, -1,-113,-109, -9,-106, -36, -6, 15, -24, -25,-122,-107; /M: SY='Y'; M= -15, 21, 2, -44, 17, -59, 9, -45, -31, -10, -95, -57,-119, -30, -49, -32, -55, 4,-100, 68; /M: SY='C'; M= 36, 55, -48, -60,-104, -53, -21, -19,-111, 12, -38, -13,-117,-108,-114, -14, -97, 27,-124,-107; /M: SY='E'; M= -12, -22, 7, 43,-120, -53, 5,-114, 14, -61,-109, 14, -18, -16, -9, -14, -14, -30,-126,-111; /M: SY='Q'; M= -34, -16, 0, -4, -61, -43, 6,-113, -17, -26, -16, 16,-113, 35, 11, 26, -16, -71,-125,-107; /I: I=-26; MD=-67; /M: SY='Q'; M= -4,-127,-113,-107,-118, -72, -3, -23, 15, -39, 11, 19,-123, 21, 17, -28,-110,-113, 13, -27; D=-26; /I: I=-26; MI=0; MD=-67; IM=0; DM=-67; /M: SY='E'; M= -51,-131, -29, 38,-124,-128,-114, -19, -10, -23,-111,-113,-121, 26, 10, -49, -59, -16,-133,-119; D=-26; /I: I=-26; DM=-67; /M: SY='K'; M= -50, -41, -42, 16, -56,-122,-114,-131, 45, -62,-122, -6, -55, -1, -99, 4, -43,-127,-134,-122; D=-26; /I: I=-26; DM=-67; /M: SY='L'; M= -22, -8, -32, -48,-115, -26, -14, -35, -30, 13, -11, -56, -67,-118,-122, -5, -54, -22,-133, -29; D=-26; /I: I=-26; DM=-67; /M: SY='Q'; M=-131,-146,-129, -33, -43, -54, 2, -22, -51, -28, -36, -29,-140, 42, -45, -75, -58, -76,-142, -52; /M: SY='V'; M= -19,-143, -62, -37,-138, -60,-137, -76, -9, -53,-126,-132, -17, -49, -15, -79, -54, 8,-150,-137; /M: SY='Q'; M= -25,-148, -43, -75, -22, -65,-135, -54, -53, -69, -12, -10,-146, -5,-136, -8, -75,-136,-148, -46; /M: SY='N'; M= 7,-145,-138,-139,-143, -27,-139,-137, -67, -13,-131, 12, -41, -56,-141, -80, -63,-135,-155,-144; /M: SY='M'; M= -10,-150,-143, -16,-145, -51,-146, -66,-142, -50, 0, -66, -63, -51,-147, -81, -53, -15,-159,-146; /M: SY='E'; M= -64,-154,-132, 15,-155, -62,-142,-145,-136, -69,-145, -40,-147, -32,-142, 8,-133, -36,-164,-151; /M: SY='D'; M=-148,-160, 14, -72,-161, -67,-140,-158, -42, -65,-151, 8,-154, -33, -29,-137, -27,-157,-172,-153; /M: SY='Q'; M= -29,-164,-142, -12,-166, -62,-146,-160, -31,-160,-152,-143, -28, -5, -9, -68,-145, -79,-164,-156; /M: SY='S'; M= -50,-158, -43, -31,-157,-152,-148, -56, -30, -70,-147,-141,-154,-137, -27, 1, -70, -60,-167,-152; /M: SY='P'; M= -59,-163,-152, -54,-156,-156,-155, -25, -52, -51,-144,-150, 5,-145, -48, -12, -63,-142,-166,-155; /M: SY='S'; M=-149,-165,-155, -22, -68, -81,-157, -56,-150, -31,-143,-155,-164, -53, -50, -18,-147, -32,-169,-153; /M: SY='P'; M= -21,-166,-162, -48, -11,-163,-163, -56,-159, -51,-146,-164, 9,-158,-164,-153,-152, -61,-162,-148; /M: SY='A'; M= -15,-162, -48,-148,-163,-153,-153,-155, -76, -54,-151, -40,-162, -50, -28, -23, -69, -84,-173,-158; /M: SY='W'; M=-153,-167,-158, -46, -22,-164,-155, -57, -78, -44, -38,-155,-164, -13,-153, -19, -67,-148, 8, -55; /M: SY='R'; M= -63,-169,-145, -4,-165,-164, -18, -76, -54, -74,-152,-149,-159, -49, -1, -61, -71,-157,-172,-155; /M: SY='E'; M=-153,-172, -63, 2,-174, -64, -19,-174, -14,-171,-162, -38, -21, -49,-141, -61,-150,-171,-174,-161; /M: SY='S'; M= -83,-160, -65, -76,-164,-153,-154,-160, -14, -73,-156,-141,-157,-143,-145, 12, -9,-155,-174,-159; /M: SY='N'; M=-154, -9, -15, -13,-165,-160,-149,-159,-144, -56,-155, -5,-163, -50, -50, -53,-148, -79,-179,-161; /M: SY='L'; M=-153,-165, -48, -78,-147, -35,-161,-136,-163, 4,-136,-160, -42,-159,-166, -77,-153, -41,-170,-155; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 14 in 14 different sequences |
| Number of true positive hits | 14 in 14 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
14 sequences
SETD3_CALJA (B0VX69), SETD3_CANLF (E2RBS6), SETD3_CHICK (Q5ZML9), SETD3_DANRE (Q7SXS7), SETD3_DASNO (C1FXW2), SETD3_DROME (Q9W3U1), SETD3_HUMAN (Q86TU7), SETD3_MOUSE (Q91WC0), SETD3_OTOGA (B5FW36), SETD3_PAPAN (A9X1D0), SETD3_PLEMO (B1MTJ4), SETD3_RAT (G3V6U9), SETD3_RHIFE (B2KI88), SETD3_XENTR (B7ZUF3)» more
|
| PDB [Detailed view] |
20 PDB
3SMT; 6ICT; 6ICV; 6JAT; 6MBJ; 6MBK; 6MBL; 6OX0; 6OX1; 6OX2; 6OX3; 6OX4; 6OX5; 6V62; 6V63; 6WK1; 6WK2; 7LMS; 7W28; 7W29 » more |